Evaluation of the profile errors in the drugs Infusion through the use of app with Anesthesiologists: An overwiew / Avaliação dos erros de perfil na infusão de medicamentos através do uso de aplicativo com anestesiologistas: uma visão geral

 Is has been widely discussed hospital safety and strategies that can be taken to minimize risks in hospital care. Anesthesiology is the only medical class that prescribes, dilutes and administers the drugs. Adding to the high frequency of these administrations creates a scenario conducive to avoidable medical failures. Based on this problem, we identify this particular medical class that has a constant risk of dealing directly with complex situations and whose actions have a direct influence on the outcome of health care. The two main errors associated with medication were: Labels of the same color and size but with different concentrations and the color of the letters printed on the ampules. Finally, human error, delegating medication to third parties. These finding provides new insight about aspects that could importantly interfere with patient safe

Photosynthesis, resource acquisition and growth responses of two biomass crops subjected to water stress

This study compares photosynthesis, growth, 13C and 15N labelling patterns of two biomass crops (Arundo donax L. and Panicum virgatum L.) grown under water stress in greenhouse conditions. Plants were exposed to three water stress levels: control (C, 100% Pot Capacity), mild stress (MS, 50% PC) and severe stress (SS, 25% PC). Photosynthesis, fluorescence parameters and relative water content were measured at the beginning (Ti) and the end of the experiment (Tf). Biomass parameters were measured at Tf. Short-term double labelling with 13C and 15N stable isotopes was performed in both species. Isotopic analyses of total organic matter, total soluble sugars and the CO2 respired were undertaken at T0 (prelabelling), T1 (24h after labelling) and T2 (7 days after labelling). Immediately after the 13C and 15N labelling, stems and rhizomes seemed to be the main sinks for labelled carbon and nitrogen in both species. Moreover, not all of the labelled carbon and nitrogen substrate was used by plant metabolism after seven days. Decreases in photosynthesis parameters were observed as a consequence of the increase in water stress (WS) in both species, with a greater magnitude decline in giant reed than in switchgrass. A decrease in height, number of green leaves and total dry weight due to WS was observed in both species. Both species were more 13C-enriched and more 15N-depleted during the increases in WS due to lower stomatal conductance and transpiration. In general, WS accelerated plant phenology and, consequently, the accumulation of storage compounds in the rhizome occurred in response to stress. This effect was more clearly visible in switchgrass than in giant reed

Drought Impact on the Morpho‐Physiological Parameters of Perennial Rhizomatous Grasses in the Mediterranean Environment

The selection of non‐food crops for bioenergy production in limiting environments is a priority for energy security and climate change mitigation. Therefore, more studies are needed on the interactions between species and environmental factors in specific sites which allows their selection for biomass production. The objective of this work is to study the impact of drought on the morpho‐physiological parameters of perennial rhizomatous grasses Panicum virgatum L., Miscanthus × giganteus, and Arundo donax L. in the Mediterranean environment. Plants were grown on field and trials were carried out under support‐irrigation and rainfed conditions during two consecutive years. Morpho‐physiological parameters were measured in May, June and August, and dry biomass at the end of the experiment. Under rainfed conditions, A. donax presented the highest photosynthesis rate (25, 15 and 10 CO2 m−2 s−1), relative water content (85-90%), and dry biomass (~4500 g plant−1) compared with P. virgatum (20, 5 and 5 CO2 m−2 s−1, 65-85% RWC and ~1400 g plant−1) and Miscanthus (18, 4 and 0 CO2 m−2 s−1, 80-10% RWC and ~260 g plant−1). It is concluded that A. donax would be the best perennial rhizomatous grass to be used as bioenergy crop under Mediterranean conditions

A atuação argumentativa do enunciador em dois sermões de Vieira: o contexto histórico revisto numa cosmovisão atual

RESUMO: Neste artigo, considera-se a argumentação como uma atividade linguístico-discursiva realizada  em determinada situação, com finalidade  persuasiva do sujeito enunciador sobre o outro na interação  Objetiva-se demonstrar,  pela análise qualitativa  de dois sermões de Vieira – Sermões XIV e XXVII-, como se dá a mise-en-scène do enunciador perante seu público destinatário, com o fim de levá-lo à aceitação de teses apresentadas.  A fundamentação teórica relaciona-se com os princípios de teorias do discurso, entre elas  a Semiolinguística (CHARAUDEAU, 2008), que defende a relação entre forma  e  sentido subsequente, relacionando-os com  teorias da enunciação. Serão observadas as condições situacionais  à época dos Sermões, comparando-as com a noção  atual de de(s)colonização dos discursos relacionados às populações afrodescendentes. Considerações históricas a respeito do contexto situacional são importantes pois, segundo a Teoria Semiolinguística, há íntima relação entre o uso da língua, o contrato comunicativo, os dados situacionais e a performance argumentativa dos enunciadores no discurso.   Palavras- chave: Discurso argumentativo. Contrato comunicativo. Contexto social. Ação e influênci

Text and Construction of Senses: Proposals for Reading and Interpretation

Discute-se a análise de inferências em textos, com o objetivo de demonstrar que todo sentido, mesmo o literal, inclui implícitos discursivos em diferentes graus. O ato de compreensão/ interpretação desses enunciados envolve vários processos inferenciais, o que significa dizer que o leitor crítico deve estar atento não só às questões lógicas ou linguísticas stricto sensu, como também às discursivas e/ou retórico-argumentativas que ocorrem nos diversos gêneros de textos e que são fundamentais para a construção dos sentidos de uma produção textual. Um dos objetivos deste artigo consiste em apresentar propostas didático-pedagógicas para o ensino de leitura e de interpretação textual.Analysis of inferences in texts, with the objective of demonstrating that the sense, even the literal one, includes implicit informations in the discourse in different degrees. The comprehension/interpretation of these texts indicates operations of inference, what it means that the reader must have attention to the logical questions or to the linguistic sense and to the discursive or argumentative ones in different kinds of texts and that they are important to the construction of the sense of a text. On of the objectives of this paper consists on the presentation of didactic proposals for the teaching of textual reading and interpretation

Acid-sensing ion channels 1a (ASIC1a) inhibit neuromuscular transmission in female mice

Acid-sensing ion channels (ASIC) open in response to extracellular acidosis. ASIC1a, a particular subtype of these channels, has been described to have a postsynaptic distribution in the brain, being involved not only in ischemia and epilepsy, but also in fear and psychiatric pathologies. High-frequency stimulation of skeletal motor nerve terminals (MNTs) can induce presynaptic pH changes in combination with an acidification of the synaptic cleft, known to contribute to muscle fatigue. Here, we studied the role of ASIC1a channels on neuromuscular transmission. We combined a behavioral wire hanging test with electrophysiology, pharmacological, and immunofluorescence techniques to compare wild-type and ASIC1a lacking mice (ASIC1a −/− knockout). Our results showed that 1) ASIC1a −/− female mice were weaker than wild type, presenting shorter times during the wire hanging test; 2) spontaneous neurotransmitter release was reduced by ASIC1a activation, suggesting a presynaptic location of these channels at individual MNTs; 3) ASIC1a-mediated effects were emulated by extracellular local application of acid saline solutions (pH = 6.0; HEPES/MES-based solution); and 4) immunofluorescence techniques revealed the presence of ASIC1a antigens on MNTs. These results suggest that ASIC1a channels might be involved in controlling neuromuscular transmission, muscle contraction and fatigue in female mice.Fil: Urbano Suarez, Francisco Jose. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Fisiología, Biología Molecular y Neurociencias. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Instituto de Fisiología, Biología Molecular y Neurociencias; ArgentinaFil: Lino, Noelia Gisele. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Fisiología, Biología Molecular y Neurociencias. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Instituto de Fisiología, Biología Molecular y Neurociencias; ArgentinaFil: González Inchauspe, Carlota María Fabiola. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Fisiología, Biología Molecular y Neurociencias. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Instituto de Fisiología, Biología Molecular y Neurociencias; ArgentinaFil: Gonzalez, Laura Elisabeth. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Fisiología, Biología Molecular y Neurociencias. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Instituto de Fisiología, Biología Molecular y Neurociencias; ArgentinaFil: Colettis, Natalia Claudia. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Fisiología, Biología Molecular y Neurociencias. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Instituto de Fisiología, Biología Molecular y Neurociencias; ArgentinaFil: Vattino, Lucas Gabriel. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Fisiología, Biología Molecular y Neurociencias. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Instituto de Fisiología, Biología Molecular y Neurociencias; ArgentinaFil: Wunsch, Amanda M.. University of Iowa; Estados UnidosFil: Wemmie, John A.. University of Iowa; Estados UnidosFil: Uchitel, Osvaldo Daniel. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Fisiología, Biología Molecular y Neurociencias. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Instituto de Fisiología, Biología Molecular y Neurociencias; Argentin

Mental Health Problems and Related Factors in Ecuadorian College Students

Although the mental health problems of college students have been the subject of increasing research, there are no studies about its prevalence in Ecuadorian college students. The aim of this study was to determine the mental health problems and their associated factors in Ecuadorian freshmen university students. A sample of 1092 students (53.7% women; mean age = 18.3 years) were recruited from the Technical Particular University of Loja (Ecuador). Socio-demographic, academic, and clinical characteristics were gathered, as well as information on the participants’ mental health through a number of mental health screens. Prevalence of positive screens was 6.2% for prevalence of major depressive episodes, 0.02% for generalized anxiety disorders, 2.2% for panic disorders, 32.0% for eating disorders, 13.1% for suicidal risk. Mental health problems were significantly associated with sex, area of study, self-esteem, social support, personality and histories of mental health problems. The findings offer a starting point for identifying useful factors to target prevention and intervention strategies aimed at university studentsThis study was funded by grant PY250 from the Universidad Técnica Particular de Loja (Ecuador)S

Superior Antibacterial Activity of Integral Lemon Pectin Extracted via Hydrodynamic Cavitation

Pectin extracted via hydrodynamic cavitation in water only from waste lemon peel and further isolated via freeze drying displays significant antibacterial activity against Staphylococcus aureus, a Gram positive pathogen which easily contaminates food. The antibacterial effect of the new IntegroPectin is largely superior to that of commercial citrus pectin, opening the way to advanced applications of a new bioproduct now obtainable in large amounts and at low cost from citrus juice industry's waste