Results of a 0.03- scale aerodynamic characteristics investigation of Boeing 747 carrier (model no. AX 1319 I-1) mated with a space shuttle orbiter (model 45-0) conducted in the Boeing transonic wind tunnel (CA5), volume 1

The performance, stability, and control characteristics of various carrier aircraft configurations are presented. Aerodynamic characteristics of the carrier mated with the Orbiter, carrier alone, and Orbiter alone were investigated. Carrier support system tare and interference effects were determined. Six-component force and moment data were recorded for the carrier and Orbiter. Buffet onset characteristics of the carrier vertical tail and horizontal tail were recorded. Angles of attack from -3 deg through 26 deg and angles of slideslip between +12 deg and -12 deg were investigated at Mach numbers from 0.15 through 0.70. Photographs are included

Metastability of life

The physical idea of the natural origin of diseases and deaths has been presented. The fundamental microscopical reason is the destruction of any metastable state by thermal activation of a nucleus of a nonreversable change. On the basis of this idea the quantitative theory of age dependence of death probability has been constructed. The obtained simple Death Laws are very accurately fulfilled almost for all known diseases.Comment: 3 pages, 4 figure

Detection of Asynchronous Message Passing Errors Using Static Analysis

Concurrent programming is hard and prone to subtle errors. In this paper we present a static analysis that is able to detect some commonly occurring kinds of message passing errors in languages with dynamic process creation and communication based on asynchronous message passing. Our analysis is completely automatic, fast, and strikes a proper balance between soundness and completeness: it is effective in detecting errors and avoids false alarms by computing a close approximation of the interprocess communication topology of programs. We have integrated our analysis in dialyzer, a widely used tool for detecting software defects in Erlang programs, and demonstrate its effectiveness on libraries and applications of considerable size. Despite the fact that these applications have been developed over a long period of time and are reasonably well-tested, our analysis has managed to detect a significant number of previously unknown message passing errors in their code

Angiographic embolization in the treatment of arterial pelvic hemorrhage: evaluation of prognostic mortality-related factors

PURPOSE: The control of arterial bleeding associated with pelvic ring and acetabular fractures (PRAF) remains a challenge for emergency trauma care. The aim of the present study was to uncover early prognostic mortality-related factors in PRAF-related arterial bleedings treated with transcatheter angiographic embolization (TAE). METHODS: Forty-nine PRAF patients (46 pelvic ring and three acetabular fractures) with arterial pelvic bleeding controlled with TAE (within 24 h) were evaluated. RESULTS: All large arterial disruptions (n = 7) were seen in type C pelvic ring injuries. The 30-day mortality in large vessel (iliac artery) bleeding was higher (57 %) than in medium- or small-size artery bleeding (24 %). Overall 30-day mortality was 29 %. No statistically significant difference in the first laboratory values between the survivors and nonsurvivors was found. However, after excluding patients dying of head injuries (n = 5), a reasonable cut-off value was identified for the base excess (BE; lower than −10 mmol/l) obtained on admission. CONCLUSIONS: PRAF patients with exsanguinating bleeding from the large pelvic artery have the worst prognosis. Very low BE values (<−10.0 mmol/l) on admission for exsanguinating patients have a negative predictive value for survival, thus anticipating a poor outcome in bleeding controlled with TAE only and an increased risk of death. In critical cases, an aggressive bleeding control protocol prompts extraperitoneal pelvic packing prior to TAE. PRAF-related rupture of the external iliac artery is rare and indicates surgical techniques in controlling and restoring blood supply to the lower leg

Results of a 0.03-scale aerodynamic characteristics investigation of a Boeing 747 carrier (model no. AX 1319 I-1) mated with a space shuttle orbiter (model 45-0) conducted in the Boeing transonic wind tunnel (CA5), volume 2

For abstract, see N75-33162

Results of a 0.03-scale aerodynamic characteristics investigation of a Boeing 747 carrier (model no. AX 1319 I-1) mated with a space shuttle orbiter (model 45-0) conducted in the Boeing transonic wind tunnel (CA5)

For abstract, see N75-33162

A fully integrated microfluidic device for point of care monitoring of antithrombotics

© 2016 The Royal Society of Chemistry. The simplicity and efficiency of point of care diagnostics have revolutionised patient care. Current methods for measuring hypercoagulability often require trained technicians, large blood volumes, and result in long turnaround times. Standard testing for hypercoagulable disorders is performed in the central laboratory using automated coagulation analysers. However the trend is moving towards the development and implementation of point of care testing, as a result of the ever increasing number of patients on antithrombotic therapy. We present a novel microfluidic device and assay for monitoring the effect of two anticoagulants, unfractionated heparin (UFH) and low molecular weight heparin (LMWH). The assay is based on the anti-Xa assay principle but uses fluorescence detection. Our device is a disposable laminate microfluidic strip, fabricated from the cyclic polyolefin (COP), Zeonor®, which is extremely suitable for application to fluorescent device platforms. We present data on the execution of the anti-Xa assay in this microfluidic format, demonstrating that the assay can be used to measure both UFH and LMWH in human plasma samples from 0 to 1 U mL-1, with a rapid result obtained within 30-60 seconds