18,027 research outputs found

    Intensity correlations and entanglement by frequency doubling in a dual ported resonator

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    We show that non-classical intensity correlations and quadrature entanglement can be generated by frequency doubling in a resonator with two output ports. We predict twin-beam intensity correlations 6 dB below the coherent state limit, and that the product of the inference variances of the quadrature fluctuations gives an Einstein-Podolsky-Rosen (EPR) correlation coefficient of V_EPR = 0.6 < 1. Comparison with an entanglement source based on combining two frequency doublers with a beam splitter shows that the dual ported resonator provides stronger entanglement at lower levels of individual beam squeezing. Calculations are performed using a self-consistent propagation method that does not invoke a mean field approximation. Results are given for physically realistic parameters that account for the Gaussian shape of the intracavity beams, as well as intracavity losses.Comment: 12 pages, 9 figures, normalization corrected, fig 3 and fig 7 update

    Sifat Mekanik Berkas Vaskular Batang Kelapa Sawit

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    The objective of the project is to investigate the relationship between the stress-strain characteristics of oil palm trunk vascular bundles and its moisture content. Based on the stress-strain graphs, the mechanical characteristics are then related to the microstructure of the vascular bundles. The results show that for all samples tested, 3 zones of deformation are found i.e an initial zone that is slightly curving, a plateau zone and finally a linear zone. The existence of the plateau zone is then explained in terms of the vascular bundle microstructure. AJ; a result of the presence of the plateau zone, the stress-strain curve is then described by 2 modulus of elasticity i.e the initial modulus and final modulus. The final modulus was found to be higher than the initial modulus thus indicating that the vascular bundles become stiffer after encountering the plateau zone. The maximum stress and final modulus of the vascular bundles were found to increase when the moisture content of the vascular bundles decreased

    Choosing Wavelet Methods, Filters, and Lengths for Functional Brain Network Construction

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    Wavelet methods are widely used to decompose fMRI, EEG, or MEG signals into time series representing neurophysiological activity in fixed frequency bands. Using these time series, one can estimate frequency-band specific functional connectivity between sensors or regions of interest, and thereby construct functional brain networks that can be examined from a graph theoretic perspective. Despite their common use, however, practical guidelines for the choice of wavelet method, filter, and length have remained largely undelineated. Here, we explicitly explore the effects of wavelet method (MODWT vs. DWT), wavelet filter (Daubechies Extremal Phase, Daubechies Least Asymmetric, and Coiflet families), and wavelet length (2 to 24) - each essential parameters in wavelet-based methods - on the estimated values of network diagnostics and in their sensitivity to alterations in psychiatric disease. We observe that the MODWT method produces less variable estimates than the DWT method. We also observe that the length of the wavelet filter chosen has a greater impact on the estimated values of network diagnostics than the type of wavelet chosen. Furthermore, wavelet length impacts the sensitivity of the method to detect differences between health and disease and tunes classification accuracy. Collectively, our results suggest that the choice of wavelet method and length significantly alters the reliability and sensitivity of these methods in estimating values of network diagnostics drawn from graph theory. They furthermore demonstrate the importance of reporting the choices utilized in neuroimaging studies and support the utility of exploring wavelet parameters to maximize classification accuracy in the development of biomarkers of psychiatric disease and neurological disorders.Comment: working pape

    Entanglement and statistics in Hong-Ou-Mandel interferometry

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    Hong-Ou-Mandel interferometry allows one to detect the presence of entanglement in two-photon input states. The same result holds for two-particles input states which obey to Fermionic statistics. In the latter case however anti-bouncing introduces qualitative differences in the interferometer response. This effect is analyzed in a Gedankenexperiment where the particles entering the interferometer are assumed to belong to a one-parameter family of quons which continuously interpolate between the Bosonic and Fermionic statistics.Comment: 7 pages, 3 figures; minor editorial changes and new references adde

    3D freeform surfaces from planar sketches using neural networks

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    A novel intelligent approach into 3D freeform surface reconstruction from planar sketches is proposed. A multilayer perceptron (MLP) neural network is employed to induce 3D freeform surfaces from planar freehand curves. Planar curves were used to represent the boundaries of a freeform surface patch. The curves were varied iteratively and sampled to produce training data to train and test the neural network. The obtained results demonstrate that the network successfully learned the inverse-projection map and correctly inferred the respective surfaces from fresh curves

    Experimental realization of strange nonchaotic attractors in a quasiperiodically forced electronic circuit

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    We have identified the three prominent routes, namely Heagy-Hammel, fractalization and intermittency routes, and their mechanisms for the birth of strange nonchaotic attractors (SNAs) in a quasiperiodically forced electronic system constructed using a negative conductance series LCR circuit with a diode both numerically and experimentally. The birth of SNAs by these three routes is verified from both experimental and their corresponding numerical data by maximal Lyapunov exponents, and their variance, Poincar\'e maps, Fourier amplitude spectrum, spectral distribution function and finite-time Lyapunov exponents. Although these three routes have been identified numerically in different dynamical systems, the experimental observation of all these mechanisms is reported for the first time to our knowledge and that too in a single second order electronic circuit.Comment: 21 figure

    Investigation of the Roles of Toxin-Coregulated Pili and Mannose-Sensitive Hemagglutinin Pili in the Pathogenesis of Vibrio cholerae O139 Infection

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    In this study, adult volunteers were fed tcpA and mshA deletion mutants of V. cholerae O139 strain CVD 112 to determine the role of toxin-coregulated pili (TCP) and mannose-sensitive hemagglutinin (MSHA) in intestinal colonization. Eight of 10 volunteers who received CVD 112 or CVD 112 ΔmshA shed the vaccine strains in their stools; the geometric mean peak excretion for both groups was 1.4 × 105 CFU/g of stool. In contrast, only one of nine recipients of CVD 112 ΔtcpA shed vibrios in his stool (P \u3c 0.01); during the first 24 h after inoculation, 3 × 102 CFU/g was recovered from this volunteer. All recipients of CVD 112 and 8 (80%) of the recipients of CVD 112 ΔmshA developed at least a fourfold rise in vibriocidal titer after immunization. In contrast, only one (11%) of the nine recipients of CVD 112 ΔtcpA developed a fourfold rise in vibriocidal titer (P \u3c 0.01). We conclude that TCP are an important colonization factor of V. cholerae O139 and probably of El Tor V. cholerae O1. In contrast, MSHA does not appear to promote intestinal colonization in humans

    Towards dynamically consistent real-time gait pattern generation for full-size humanoid robots

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    We propose a two-stage gait pattern generation scheme for the full-scale humanoid robots, that considers the dynamics of the system throughout the process. The fist stage is responsible for generating semi-dynamically consistent step position and step time information, while the second stage incorporated with multi-body dynamics system is responsible for generation of gait pattern that is feasible and stable on the full-scale multi-degree-of-freedom humanoid robot. The approach allows for very rapid gait pattern regeneration during the swing phase of motion and includes information about present dynamic state when regenerating the new pattern. The paper contains description of a developed method, as well as experimental results proving its effectiveness

    Clinical translation of [18F]ICMT-11 for measuring chemotherapy-induced caspase 3/7 activation in breast and lung cancer

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    Background: Effective anticancer therapy is thought to involve induction of tumour cell death through apoptosis and/or necrosis. [18F]ICMT-11, an isatin sulfonamide caspase-3/7-specific radiotracer, has been developed for PET imaging and shown to have favourable dosimetry, safety, and biodistribution. We report the translation of [18F]ICMT-11 PET to measure chemotherapy-induced caspase-3/7 activation in breast and lung cancer patients receiving first-line therapy. Results: Breast tumour SUVmax of [18F]ICMT-11 was low at baseline and unchanged following therapy. Measurement of M30/M60 cytokeratin-18 cleavage products showed that therapy was predominantly not apoptosis in nature. While increases in caspase-3 staining on breast histology were seen, post-treatment caspase-3 positivity values were only approximately 1%; this low level of caspase-3 could have limited sensitive detection by [18F]ICMT-11-PET. Fourteen out of 15 breast cancer patients responded to first–line chemotherapy (complete or partial response); one patient had stable disease. Four patients showed increases in regions of high tumour [18F]ICMT-11 intensity on voxel-wise analysis of tumour data (classed as PADS); response was not exclusive to patients with this phenotype. In patients with lung cancer, multi-parametric [18F]ICMT-11 PET and MRI (diffusion-weighted- and dynamic contrast enhanced-MRI) showed that PET changes were concordant with cell death in the absence of significant perfusion changes. Conclusion: This study highlights the potential use of [18F]ICMT-11 PET as a promising candidate for non-invasive imaging of caspase3/7 activation, and the difficulties encountered in assessing early-treatment responses. We summarize that tumour response could occur in the absence of predominant chemotherapy-induced caspase-3/7 activation measured non-invasively across entire tumour lesions in patients with breast and lung cancer
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