1,501 research outputs found

    Optimizing condition numbers

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    In this paper we study the problem of minimizing condition numbers over a compact convex subset of the cone of symmetric positive semidefinite n×nn\times n matrices. We show that the condition number is a Clarke regular strongly pseudoconvex function. We prove that a global solution of the problem can be approximated by an exact or an inexact solution of a nonsmooth convex program. This asymptotic analysis provides a valuable tool for designing an implementable algorithm for solving the problem of minimizing condition numbers

    Reliability of measuring thoracic kyphosis angle, lumbar lordosis angle and straight leg raise with an inclinometer

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    Licensed under the terms of the Creative Commons Attribution non-commercial License (http://creativecommons.org/licenses/by-nc/3.0/) which permits unrestricted, non-commercial use, distribution and reproduction in any medium, providing that the work is properly citedPurpose: Several non-invasive measurement methods have been described in the literature for recording thoracic kyphosis, lumbar lordosis and straight leg raise (SLR). However, attempts to quantify the reliability of the inclinometer in these measurements are scarce. In addition, existing reliability studies within the literature were found to use small sample sizes. The aim of this investigation was to examine the intra-rater reliability of the chief investigator (SM), in order to provide clinicians with data that will allow them to better measure sagittal spinal posture and SLR. A blinded test-retest design was performed to determine the intra-rater reliability of thoracic kyphosis, lumbar lordosis and SLR when assessed using an Isomed inclinometer in normals. Methods. Thirty asymptomatic subjects were assessed on two occasions separated by a time interval of 1 hour to reduce investigator memory bias. Thoracic and lumbar measurements were recorded in a relaxed standing position using an inclinometer; SLR of the dominant leg was assessed with subjects in the supine position. Intraclass correlation coefficients (ICC), 95% confidence intervals (CI), and standard errors of measurement (SEM) were analysed to determine measurement reliability. Results. The chief investigator demonstrated excellent intra-rater reliability in the measurements of thoracic kyphosis, lumbar lordosis and SLR. ICC (2,3) values for all three variables exceeded the 0.90 threshold suggesting that the reliability of these measures are acceptable for clinical application. Conclusions. The inclinometer technique employed in this study to record thoracic kyphosis, lumbar lordosis and SLR is a reliable measurement method.Peer reviewe

    The electric field response to the growth phase and expansion phase onset of a small isolated substorm

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    International audienceWe capitalise on the very large field of view of the Halley HF radar to provide a comprehensive description of the electric field response to the substorm growth phase and expansion phase onset of a relatively simple isolated substorm ( |AL| 12 h) of magnetic quiescence, such that prior to the start of the growth phase, the apparent latitudinal motion of the radar backscatter returns is consistent with the variation in latitude of the quiet-time auroral oval with magnetic local time. The growth phase is characterised by an increasing, superimposed equatorward motion of the equatorward edge of the radar backscatter as the auroral oval expands. Within this backscatter region, there is a poleward gradient in the Doppler spectral width, which we believe to correspond to latitudinal structure in auroral emissions and magnetospheric precipitation. During the growth phase the ionospheric convection is dominated by a relatively smooth large-scale flow pattern consistent with the expanding DP2 (convection) auroral electrojets. Immediately prior to substorm onset the ionospheric convection observed by the radar in the midnight sector has a predominantly equatorward flow component. At substorm onset a dramatic change occurs and a poleward flow component prevails. The timing and location are quite remarkable. The timing of the flow change is within one minute of the dispersionless injection observed at geostationary orbit and the Pi2 magnetic signature on the ground. The location shows that this sudden change in flow is due to the effect of the upward field aligned current of the substorm current wedge imposed directly within the Halley radar field of view

    Prox-regularity of rank constraint sets and implications for algorithms

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    We present an analysis of sets of matrices with rank less than or equal to a specified number ss. We provide a simple formula for the normal cone to such sets, and use this to show that these sets are prox-regular at all points with rank exactly equal to ss. The normal cone formula appears to be new. This allows for easy application of prior results guaranteeing local linear convergence of the fundamental alternating projection algorithm between sets, one of which is a rank constraint set. We apply this to show local linear convergence of another fundamental algorithm, approximate steepest descent. Our results apply not only to linear systems with rank constraints, as has been treated extensively in the literature, but also nonconvex systems with rank constraints.Comment: 12 pages, 24 references. Revised manuscript to appear in the Journal of Mathematical Imaging and Visio

    Acebutolol in cardiac arrhythmiaa

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    Acebutolol (Sectral), a new beta-adrenoceptor antagonist, was used in 44 patients with cardiac arrhythmias (53 episodes). It was used intravenously (12,5 and 25 mg), orally (100 mg every 8 hours) or in combination with quinidine. Acebutolol was most effective in supraventricular tachyarrhythmias, to control the ventricular response when digital's was ineffective, as a synergist with quinidine to convert patients to sinus rhythm, or prophylactically to prevent relapse to atrial fibrillation. It also terminated ventricular tachycardia in two patients. Side-effects occurred in three ill patients.S. Afr. Med. J., 48, 821 (1974

    Motives of some Fano varieties

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    We study the Fano varieties of projective k-planes lying in hypersurfaces and investigate the associated motives. © 2008 Springer-Verlag

    Semidefinite Representation of the kk-Ellipse

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    The kk-ellipse is the plane algebraic curve consisting of all points whose sum of distances from kk given points is a fixed number. The polynomial equation defining the kk-ellipse has degree 2k2^k if kk is odd and degree 2k(kk/2)2^k{-}\binom{k}{k/2} if kk is even. We express this polynomial equation as the determinant of a symmetric matrix of linear polynomials. Our representation extends to weighted kk-ellipses and kk-ellipsoids in arbitrary dimensions, and it leads to new geometric applications of semidefinite programming.Comment: 16 pages, 5 figure

    The effects of respiratory muscle strength training on individuals with Parkinson\u27s disease

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    The purpose of this study was to determine if respiratory muscle strength training (RMST) results in increased measures of respiratory function, improved vocal quality, and improved quality of life as perceived by the participants. Data obtained by this study adds to the body of knowledge regarding clinical use of RMST for SLPs working with patients with Parkinson\u27s disease (PD). The study was comprised of a 13-week ABAB within-subject design with a baseline period, five weeks of respiratory training (Phase 1), three weeks without training (Detraining Phase), and five weeks with training (Phase 2). Three individuals with moderate PD (1M, 2F) participated. They were taught to use the PowerLung® respiratory training device and completed twice daily sessions of expiratory and inspiratory muscle training, five days per week. Outcome measures included maximum inspiratory and expiratory pressures (MIP and MEP, respectively); forced vital capacity (FVC), percent predicted forced vital capacity (FVC%), and forced expiratory volume in 1 second (FEV1); and sustained vowel phonation. Measurements were taken at baseline, before and after detraining (where applicable), and at the end of the study. Results indicated improved maximum respiratory pressures for all participants from baseline to end of study. No participant showed significant changes in FVC, FVC%, and FEV 1, and results of sustained vowel phonation varied. Participants\u27 vocal quality was evaluated by three independent raters as well as the subjects themselves and two conversation partners. Two CSD graduate students and one certified SLP rated subjects\u27 voices at baseline and at the end of treatment using recorded conversation samples and the GRBAS Voice Rating Scale (Hirano, 1981). Improvement in vocal quality was perceived in two participants, and no change was seen in the other. Participants and two conversation partners completed the Perceptual Rating Form to report on vocal quality. Participants noted improvement in vocal quality; conversation partners reported both improvement and decline in various aspects of two participants\u27 vocal quality. Participants completed two surveys regarding the impact of their voice on overall communication and quality of life. These surveys, completed at the start of the study and at completion of each phase, were the Voice Handicap Index (VHI) (Jacobson, et al., 1997) and The Communicative Participation Item Bank General Short Form (Baylor et al. [under review]). Responses from participants revealed inconsistent effects of RMST on quality of life. Results of this study demonstrate that the combination of inspiratory and expiratory muscle strength training in individuals with moderate Parkinson\u27s disease may be a beneficial treatment to improve respiratory function and positively impact vocal quality and overall quality of life as it relates to communicative participation. Results from this study revealed the potential for additional research on the effects of RMST on pulmonary functions such as vital capacity (VC) and total lung capacity (TLC), which are not dependent on maximum speed and effort. Additionally, further investigation of RMST on quality of life is warranted in areas related to voice and communication, as well as overall physical and emotional wellbeing

    Psychotic experiences, working memory, and the developing brain: a multimodal neuroimaging study

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    Psychotic experiences (PEs) occur in the general population, especially in children and adolescents, and are associated with poor psychosocial outcomes, impaired cognition, and increased risk of transition to psychosis. It is unknown how the presence and persistence of PEs during early adulthood affects cognition and brain function. The current study assessed working memory as well as brain function and structure in 149 individuals, with and without PEs, drawn from a population cohort. Observer-rated PEs were classified as persistent or transient on the basis of longitudinal assessments. Working memory was assessed using the n-back task during fMRI. Dynamic causal modeling (DCM) was used to characterize frontoparietal network configuration and voxel-based morphometry was utilized to examine gray matter. Those with persistent, but not transient, PEs performed worse on the n-back task, compared with controls, yet showed no significant differences in regional brain activation or brain structure. DCM analyses revealed greater emphasis on frontal connectivity within a frontoparietal network in those with PEs compared with controls. We propose that these findings portray an altered configuration of working memory function in the brain, potentially indicative of an adaptive response to atypical development associated with the manifestation of PEs
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