Mapping Geographic Areas of High and Low Drug Adherence in Patients Prescribed Continuing Treatment for Acute Coronary Syndrome After Discharge

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/90283/1/phco.31.10.927.pd

VLSP SHARED TASK: SENTIMENT ANALYSIS

Sentiment analysis is a natural language processing (NLP) task of identifying orextracting the sentiment content of a text unit. This task has become an active research topic since the early 2000s. During the two last editions of the VLSP workshop series, the shared task on Sentiment Analysis (SA) for Vietnamese has been organized in order to provide an objective evaluation measurement about the performance (quality) of sentiment analysis tools, and encouragethe development of Vietnamese sentiment analysis systems, as well as to provide benchmark datasets for this task. The rst campaign in 2016 only focused on the sentiment polarity classication, with a dataset containing reviews of electronic products. The second campaign in 2018 addressed the problem of Aspect Based Sentiment Analysis (ABSA) for Vietnamese, by providing two datasets containing reviews in restaurant and hotel domains. These data are accessible for research purpose via the VLSP website vlsp.org.vn/resources. This paper describes the built datasets as well as the evaluation results of the systems participating to these campaigns

Mobile colistin resistance: Prevalence, mechanisms, and current detection methods

Colistin is considered the last-line antibiotic against multidrug-resistant Gram-negative bacterial infections. The global dissemination of Mobile colistin resistance mcr-harboring bacteria is threatening public health. Such isolates have been detected in various reservoirs including animals, food products, the environment, and humans. From these reservoirs, the isolates are approximate: 53% from animals; 39% from humans; 5% from the environment; and 3% from food. Bacterial distributions were: E.coli 91%; Salmonella 7%; and Klebsiella 2%. Among the 10 mcr variants, mcr-1 and mcr-9 are the most prevalent (up to 95% and 64.53%, respectively, in different studies) while other variants account for 5%. The coexistence of mcr and other antibiotic resistance genes in single isolates is a significant concern; mcr variants carried by different plasmid types increase antibiotic resistance and transfer of mcr genes to other bacteria. The hypothesis that the food chain is intimately involved in mcr gene transfer is supported by the presence of mcr-harboring isolates in animals and foods relative to humans. Cheaper, quicker, and more effective diagnostic tools for detecting colistin-resistant bacterial phenotypes and genotypes are essential and urgent. Currently, high quality tests include RPNP (99.3% specificity, 96.7% sensitivity) and MRPNP (95.4% specificity, ~100% sensitivity). LBJMR, CHROM agar, COL-APSE, and Super Polymyxin are now the best media to screen the bacteria, with near 100% selectivity. Multiplex PCR is a suitable method to quickly and accurately detect mcr genes in E. coli and Salmonella . Multi-drug resistant Gram-negative bacteria remain a global burden and need to have continuous and effective surveillance

Novel biogenic silver and gold nanoparticles for multifunctional applications: Green synthesis, catalytic and antibacterial activity, and colorimetric detection of Fe(III) ions

In this study, novel biogenic silver (AgNPs) and gold nanoparticles (AuNPs) were developed using a green approach with Ganoderma lucidum (GL) extract. The optimization of synthesis conditions for the best outcomes was conducted. The prepared materials were characterized and their applicability in catalysis, antibacterial and chemical sensing was comprehensively evaluated. The GL-AgNPs crystals were formed in a spherical shape with an average diameter of 50 nm, while GL-AuNPs exhibited multi-shaped structures with sizes ranging from 15 to 40 n

Prevalence and Risk Factors for Tuberculosis Infection among Hospital Workers in Hanoi, Viet Nam

BACKGROUND: Transmission of tuberculosis (TB) to health care workers (HCWs) is a global issue. Although effective infection control measures are expected to reduce nosocomial TB, HCWs' infection has not been assessed enough in TB high burden countries. We conducted a cross-sectional study to determine the prevalence of TB infection and its risk factors among HCWs in Hanoi, Viet Nam. METHODOLOGY/PRINCIPAL FINDINGS: A total of 300 HCWs including all staff members in a municipal TB referral hospital received an interferon-gamma release assay (IGRA), QuantiFERON-TB Gold In-Tube(TM), followed by one- and two-step tuberculin skin test (TST) and a questionnaire-based interview. Agreement between the tests was evaluated by kappa statistics. Risk factors for TB infection were analyzed using a logistic regression model. Among the participants aged from 20 to 58 years (median = 40), prevalence of TB infection estimated by IGRA, one- and two-step TST was 47.3%, 61.1% and 66.3% respectively. Although the levels of overall agreement between IGRA and TST were moderate, the degree of agreement was low in the group with BCG history (kappa = 0.29). Working in TB hospital was associated with twofold increase in odds of TB infection estimated by IGRA. Increased age, low educational level and the high body mass index also demonstrated high odds ratios of IGRA positivity. CONCLUSIONS/SIGNIFICANCE: Prevalence of TB infection estimated by either IGRA or TST is high among HCWs in the hospital environment for TB care in Viet Nam and an infection control program should be reinforced. In communities with heterogeneous history of BCG vaccination, IGRA seems to estimate TB infection more accurately than any other criteria using TST

The Ninth Data Release of the Sloan Digital Sky Survey: First Spectroscopic Data from the SDSS-III Baryon Oscillation Spectroscopic Survey

The Sloan Digital Sky Survey III (SDSS-III) presents the first spectroscopic data from the Baryon Oscillation Spectroscopic Survey (BOSS). This ninth data release (DR9) of the SDSS project includes 535,995 new galaxy spectra (median z=0.52), 102,100 new quasar spectra (median z=2.32), and 90,897 new stellar spectra, along with the data presented in previous data releases. These spectra were obtained with the new BOSS spectrograph and were taken between 2009 December and 2011 July. In addition, the stellar parameters pipeline, which determines radial velocities, surface temperatures, surface gravities, and metallicities of stars, has been updated and refined with improvements in temperature estimates for stars with T_eff<5000 K and in metallicity estimates for stars with [Fe/H]>-0.5. DR9 includes new stellar parameters for all stars presented in DR8, including stars from SDSS-I and II, as well as those observed as part of the SDSS-III Sloan Extension for Galactic Understanding and Exploration-2 (SEGUE-2). The astrometry error introduced in the DR8 imaging catalogs has been corrected in the DR9 data products. The next data release for SDSS-III will be in Summer 2013, which will present the first data from the Apache Point Observatory Galactic Evolution Experiment (APOGEE) along with another year of data from BOSS, followed by the final SDSS-III data release in December 2014.Comment: 9 figures; 2 tables. Submitted to ApJS. DR9 is available at http://www.sdss3.org/dr

The Eighth Data Release of the Sloan Digital Sky Survey: First Data from SDSS-III

The Sloan Digital Sky Survey (SDSS) started a new phase in August 2008, with new instrumentation and new surveys focused on Galactic structure and chemical evolution, measurements of the baryon oscillation feature in the clustering of galaxies and the quasar Ly alpha forest, and a radial velocity search for planets around ~8000 stars. This paper describes the first data release of SDSS-III (and the eighth counting from the beginning of the SDSS). The release includes five-band imaging of roughly 5200 deg^2 in the Southern Galactic Cap, bringing the total footprint of the SDSS imaging to 14,555 deg^2, or over a third of the Celestial Sphere. All the imaging data have been reprocessed with an improved sky-subtraction algorithm and a final, self-consistent photometric recalibration and flat-field determination. This release also includes all data from the second phase of the Sloan Extension for Galactic Understanding and Evolution (SEGUE-2), consisting of spectroscopy of approximately 118,000 stars at both high and low Galactic latitudes. All the more than half a million stellar spectra obtained with the SDSS spectrograph have been reprocessed through an improved stellar parameters pipeline, which has better determination of metallicity for high metallicity stars.Comment: Astrophysical Journal Supplements, in press (minor updates from submitted version

A Clinical and Epidemiological Investigation of the First Reported Human Infection With the Zoonotic Parasite Trypanosoma evansi in Southeast Asia.

BACKGROUND: Trypanosomais a genus of unicellular parasitic flagellate protozoa.Trypanosoma bruceispecies and Trypanosoma cruziare the major agents of human trypanosomiasis; other Trypanosomaspecies can cause human disease, but are rare. In March 2015, a 38-year-old woman presented to a healthcare facility in southern Vietnam with fever, headache, and arthralgia. Microscopic examination of blood revealed infection with Trypanosoma METHODS: Microscopic observation, polymerase chain reaction (PCR) amplification of blood samples, and serological testing were performed to identify the infecting species. The patient's blood was screened for the trypanocidal protein apolipoprotein L1 (APOL1), and a field investigation was performed to identify the zoonotic source. RESULTS: PCR amplification and serological testing identified the infecting species as Trypanosoma evansi.Despite relapsing 6 weeks after completing amphotericin B therapy, the patient made a complete recovery after 5 weeks of suramin. The patient was found to have 2 wild-type APOL1 alleles and a normal serum APOL1 concentration. After responsive animal sampling in the presumed location of exposure, cattle and/or buffalo were determined to be the most likely source of the infection, with 14 of 30 (47%) animal blood samples testing PCR positive forT. evansi. CONCLUSIONS: We report the first laboratory-confirmed case ofT. evansiin a previously healthy individual without APOL1 deficiency, potentially contracted via a wound while butchering raw beef, and successfully treated with suramin. A linked epidemiological investigation revealed widespread and previously unidentified burden ofT. evansiin local cattle, highlighting the need for surveillance of this infection in animals and the possibility of further human cases