Seismological support for the metastable superplume model, sharp features, and phase changes within the lower mantle

Recently, a metastable thermal-chemical convection model was proposed to explain the African Superplume. Its bulk tabular shape remains relatively stable while its interior undergoes significant stirring with low-velocity conduits along its edges and down-welling near the middle. Here, we perform a mapping of chemistry and temperature into P and S velocity variations and replace a seismically derived structure with this hybrid model. Synthetic seismogram sections generated for this 2D model are then compared directly with corresponding seismic observations of P (P, PCP, and PKP) and S (S, SCS, and SKS) phases. These results explain the anticorrelation between the bulk velocity and shear velocity and the sharpness and level of SKS travel time delays. In addition, we present evidence for the existence of a D" triplication (a putative phase change) beneath the down-welling structure

Innovative Service-Based Business Concepts for the Machine Tool Building Industry

Organised by: Cranfield UniversityDuring the last decade, machine tool building companies have been forced to put innovative offers on the market. Due to the technical features of their products and the prevailing organizational structures in this sector, especially product-service systems are a promising way of creating a unique selling point. In this paper, potential new business concepts for machine tool builders will be presented which aim at fulfilling basic customer needs like the increase in quality, flexibility, productivity and the reduction of lead times, costs and risks. For the implementation of these product-service systems, practical examples are given.Mori Seiki – The Machine Tool Compan

Interplay between valence and core excitation mechanisms in the breakup of halo nuclei

The phenomenon of core excitation in the breakup of a two-body halo nucleus is investigated. We show that this effect plays a significant role in the reaction dynamics and, furthermore, its interference with the valence excitation mechanism has sizable and measurable effects on the breakup angular distributions. These effects have been studied in the resonant breakup of 11Be on a carbon target, populating the resonances at 1.78 MeV (5/2+) and 3.41 MeV (3/2+). The calculations have been performed using a recently extension of the DWBA method, which takes into account the effect of core excitation in both the structure of the halo nucleus and in the reaction mechanism. The calculated angular distributions have been compared with the available data [Fukuda et al., Phys. Rev. C70,054606]. Although each of these resonances is dominated by one of the two considered mechanisms, the angular patterns of these resonances depend in a very delicate way on the interference between them. This is the first clear evidence of this effect but the phenomenon is likely to occur in other similar reactions.Comment: 5 pages, 2 figures, (Version to appear in Physical Review Letters

Modulation of Host Immunity by Human Respiratory Syncytial Virus Virulence Factors: A Synergic Inhibition of Both Innate and Adaptive Immunity

Indexación: Web of Science; Scopus.The Human Respiratory Syncytial Virus (hRSV) is a major cause of acute lower respiratory tract infections (ARTIs) and high rates of hospitalizations in children and in the elderly worldwide. Symptoms of hRSV infection include bronchiolitis and pneumonia. The lung pathology observed during hRSV infection is due in part to an exacerbated host immune response, characterized by immune cell infiltration to the lungs. HRSV is an enveloped virus, a member of the Pneumoviridae family, with a non-segmented genome and negative polarity-single RNA that contains 10 genes encoding for 11 proteins. These include the Fusion protein (F), the Glycoprotein (G), and the Small Hydrophobic (SH) protein, which are located on the virus surface. In addition, the Nucleoprotein (N), Phosphoprotein (P) large polymerase protein (L) part of the RNA-dependent RNA polymerase complex, the M2-1 protein as a transcription elongation factor, the M2-2 protein as a regulator of viral transcription and (M) protein all of which locate inside the virion. Apart from the structural proteins, the hRSV genome encodes for the non-structural 1 and 2 proteins (NS1 and NS2). HRSV has developed different strategies to evade the host immunity by means of the function of some of these proteins that work as virulence factors to improve the infection in the lung tissue. Also, hRSV NS-1 and NS-2 proteins have been shown to inhibit the activation of the type I interferon response. Furthermore, the hRSV nucleoprotein has been shown to inhibit the immunological synapsis between the dendritic cells and T cells during infection, resulting in an inefficient T cell activation. Here, we discuss the hRSV virulence factors and the host immunological features raised during infection with this virus.https://www.frontiersin.org/articles/10.3389/fcimb.2017.00367/ful

Automatic identification of gait events using an instrumented sock

Background: textile-based transducers are an emerging technology in which piezo-resistive properties of materials are used to measure an applied strain. By incorporating these sensors into a sock, this technology offers the potential to detect critical events during the stance phase of the gait cycle. This could prove useful in several applications, such as functional electrical stimulation (FES) systems to assist gait. Methods: we investigated the output of a knitted resistive strain sensor during walking and sought to determine the degree of similarity between the sensor output and the ankle angle in the sagittal plane. In addition, we investigated whether it would be possible to predict three key gait events, heel strike, heel lift and toe off, with a relatively straight-forward algorithm. This worked by predicting gait events to occur at fixed time offsets from specific peaks in the sensor signal. Results: our results showed that, for all subjects, the sensor output exhibited the same general characteristics as the ankle joint angle. However, there were large between-subjects differences in the degree of similarity between the two curves. Despite this variability, it was possible to accurately predict gait events using a simple algorithm. This algorithm displayed high levels of trial-to-trial repeatability. Conclusions: this study demonstrates the potential of using textile-based transducers in future devices that provide active gait assistance

Germanene: a novel two-dimensional Germanium allotrope akin to Graphene and Silicene

Using a gold (111) surface as a substrate we have grown in situ by molecular beam epitaxy an atom-thin, ordered, two-dimensional multi-phase film. Its growth bears strong similarity with the formation of silicene layers on silver (111) templates. One of the phases, forming large domains, as observed in Scanning Tunneling Microscopy, shows a clear, nearly flat, honeycomb structure. Thanks to thorough synchrotron radiation core-level spectroscopy measurements and advanced Density Functional Theory calculations we can identify it to a $\sqrt{3}$x$\sqrt{3}$R(30{\deg}) germanene layer in coincidence with a $\sqrt{7}$x$\sqrt{7}$R(19.1{\deg}) Au(111) supercell, thence, presenting the first compelling evidence of the birth of a novel synthetic germanium-based cousin of graphene.Comment: 16 pages, 4 figures, 1 tabl

Determining B(E1)B(E1) distributions of weakly bound nuclei from breakup cross sections using Continuum Discretized Coupled Channels calculations. Application to 11^{11}Be

A novel method to extract the $B(E1)$ strength of a weakly bound nucleus from experimental Coulomb dissociation data is proposed. The method makes use of continuum discretized coupled channels (CDCC) calculations, in which both nuclear and Coulomb forces are taken into account to all orders. This is a crucial advantage with respect to the standard procedure based on the Equivalent Photon Method (EPM) which does not properly take into account nuclear distortion, higher order coupling effects, or Coulomb-nuclear interference terms. The procedure is applied to the $^{11}$Be nucleus using two sets of available experimental data at different energies, for which seemingly incompatible $B(E1)$ have been reported using the EPM. We show that the present procedure gives consistent $B(E1)$ strengths, thus solving the aforementioned long-standing discrepancy between the two measurements.Comment: Submitted for publicatio

Deep mantle structure and the postperovskite phase transition

Seismologists have known for many years that the lowermost mantle of the Earth is complex. Models based on observed seismic phases sampling this region include relatively sharp horizontal discontinuities with strong zones of anisotropy, nearly vertical contrasts in structure, and small pockets of ultralow velocity zones (ULVZs). This diversity of structures is beginning to be understood in terms of geodynamics and mineral physics, with dense partial melts causing the ULVZs and a postperovskite solid–solid phase transition producing regional layering, with the possibility of large-scale variations in chemistry. This strong heterogeneity has significant implications on heat transport out of core, the evolution of the magnetic field, and magnetic field polarity reversals

Ag on Ge(111): 2D X-ray structure analysis of the (Wurzel)3 x (Wurzel)3 superstructure

We have studied the Ag/Ge(111)(Wurzel)3 x (Wurzel)3 superstructure by grazing-incidence X-ray diffraction. In our structural analysis we find striking similarities to the geometry of Au on Si(111). The Ag atoms form trimer clusters with an Ag-Ag distance of 2.94+-0.04°A with the centers of the trimers being located at the origins of the (Wurzel)3 x (Wurzel)3 lattice. The Ag layer is incomplete and at least one substrate layer is distorted