Avaliação comparativa de modelos de equações diferenciais com e sem delay para estudo do HLB em citros.

O objetivo deste trabalho é apresentar um modelo matemático compartimental determinístico para representar a dinâmica da doença HLB em plantações de citros, considerando a existência de período de delay (retardo) na fase de incubação da doença na planta. Esse modelo é baseado no trabalho de Braga et al (2011), que analisa a dinâmica da infecção sem considerar a existência de delay na fase citada. Uma comparação entre os resultados obtidos pelos dois modelos é realizada.CIIC 2012. No 12602

Avaliação comparativa de modelos de equações diferenciais com e sem delay para estudo do HLB em citros.

O objetivo deste trabalho é apresentar um modelo matemático compartimental determinístico para representar a dinâmica da doença HLB em plantações de citros, considerando a existência de período de delay (retardo) na fase de incubação da doença na planta. Esse modelo é baseado no trabalho de Braga et al (2011), que analisa a dinâmica da infecção sem considerar a existência de delay na fase citada. Uma comparação entre os resultados obtidos pelos dois modelos é realizada.CIIC 2012. No 12602

Lipoxidation and cancer immunity

Lipoxidation is a well-known reaction between electrophilic carbonyl species, formed during oxidation of lipids, and specific proteins that, in most cases, causes an alteration in proteins function. This can occur under physiological conditions but, in many cases, it has been associated to pathological process, including cancer. Lipoxidation may have an effect in cancer development through their effects in tumour cells, as well as through the alteration of immune components and the consequent modulation of the immune response. The formation of protein adducts affects different proteins in cancer, triggering different mechanism, such as proliferation, cell differentiation and apoptosis, among others, altering cancer progression. The divergent results obtained documented that the formation of lipoxidation adducts can have either anti-carcinogenic or pro-carcinogenic effects, depending on the cell type affected and the specific adduct formed. Moreover, lipoxidation adducts may alter the immune response, consequently causing either positive or negative alterations in cancer progression. Therefore, in this review, we summarize the effects of lipoxidation adducts in cancer cells and immune components and their consequences in the evolution of different types of cancer.publishe

Agrio et Emulsio – development of new products with vinegar and sweetpotatoes

Agrio et Emulsio project (POCI-01-0145-FEDER-023583) develops in vinegar and food emulsions areas. In line Agrio, vinegar technological ability enables the development of multiple products, by fermentative and non-fermentative prototyping. Articulating technological, laboratory and sensory tests and inspired both by the marinades in wine or vinegar of the Mediterranean gastronomy and in the traditional Portuguese recipe of “drunk” pear in red wine, two prototypes are undergoing final development, using sweet potato cultivars (Ipomoea batatas) as main ingredient. A sweet and sour “drunk” pickle has been developed by fresh pack pickling technology (without fermentation), using a spicy red wine vinegar with cinnamon and black pepper, sweetened with brown sugar and added Gin. The marinade was designed to be a ready-to-eat vegan product, with tofu and sweet potato previously salted in brine and then submerged in the marinade liquid. The marinade matrix is a diluted blend of red wine vinegar and regional liqueur wine from Ribatejo, flavored with red pepper, herbs and spices. Pre-salting in brine, maturation and the final heat treatment are fundamental for the quality and safety of both prototypes that were designed to provide innovation and convenience: new products with long shelf life, aims the preservation of seasonal/surplus raw materials.info:eu-repo/semantics/publishedVersio

Imprensa Periódica da Associação Académica da Universidade do Minho (1977-1997)

Cumprindo-se neste ano de 1997 o vigésimo aniversário da Associação Académica da Universidade do Minho, pareceu-nos oportuno assinalar esta data com a publicação do inventário da sua imprensa periódica, com base na colecção existente na Biblioteca Pública de Braga, cujo primeiro título remonta à data de fundação da AAUM

Imprensa Periódica Minhota: Subsídios para um Bibliografia

Ao publicarmos a presente bibliografia não pretendemos apresentar uma recolha exaustiva de tudo o que se tem escrito sobre a imprensa periódica dos distritos de Braga e Viana, mas tão só proporcionar um primeiro tnstrumento de trabalho a quem se propuser estudar a imprensa periódica minhota. De facto, a importância que a imprensa tem assumido para os estudos históricos parece-nos justiticsr a divulgação de trabalhos que a procurem sistematizar, por mais modestos que sejam.Incluimos na nossa recolha não só obras de maior alcance, algumas ainda no prelo, mas também pequenos contributos que por vezes se encontram perdidos em breves capítulos de monografias e neste ou naquele periódico

Prenatal tobacco exposure is related to neurobehavioral modifications in infants of adolescent mothers

INTRODUCTION: Prenatal tobacco exposure interferes with neonatal outcomes. OBJECTIVE: To determine the neonatal neurobehavioral effects of in utero tobacco exposure. METHODS: This prospective cross-sectional study included healthy, term, with birth weight appropriate for gestacional age neonates without exposure to alcohol, drugs, or infections, born to adolescent mothers without psychiatric disorders or post-traumatic stress. Infants were classified according to in utero tobacco exposure, as identified by the Composite International Diagnostic Interview administered to mothers. Neurobehavior was assessed by the Neonatal Intensive Care Unit Network Neurobehavioral Scale. Both tools were administered between 24 and 72 hours after birth. Neurobehavioral outcomes were compared between exposed and nonexposed infants by ANOVA. The associations between neurobehavioral scores and number of cigarettes smoked were studied by linear correlation. RESULTS: During the study, 928 newborns of adolescent mothers were born, and 388 were included in the study. Of these, 23 were exposed to tobacco, and 365 neonates were not exposed. There were no differences between the groups in gestational age, birth weight, post-natal age at the exam, or time between last feeding and exam. Exposed neonates showed higher scores on arousal (p = 0.004), excitability (p = 0.003), and stress/abstinence signals (p = 0.019) and a lower score on regulation (p = 0.025). After adjusting for the type of anesthesia, mode of delivery, gender, age at neurologic exam, exam duration and time between last feeding and exam, differences in arousal and excitability remained significant. The mean number of cigarettes consumed daily was positively correlated with lethargy (p = 0.013) and inversely with attention (p = 0.043). CONCLUSIONS: Neonates exposed in utero to tobacco showed worse neurobehavioral performance between 24 and 48 hours of life

Characterising cellular and molecular features of human peripheral nerve degeneration

Nerve regeneration is a key biological process in those recovering from neural trauma. From animal models it is known that the regenerative capacity of the peripheral nervous system (PNS) relies heavily on the remarkable ability of Schwann cells to undergo a phenotypic shift from a myelinating phenotype to one that is supportive of neural regeneration. In rodents, a great deal is known about the molecules that control this process, such as the transcription factors c-Jun and early growth response protein 2 (EGR2/KROX20), or mark the cells and cellular changes involved, including SOX10 and P75 neurotrophin receptor (p75NTR). However, ethical and practical challenges associated with studying human nerve injury have meant that little is known about human nerve regeneration. The present study addresses this issue, analysing 34 denervated and five healthy nerve samples from 27 patients retrieved during reconstructive nerve procedures. Using immunohistochemistry and Real-Time quantitative Polymerase Chain Reaction (RT-qPCR), the expression of SOX10, c-Jun, p75NTR and EGR2 was assessed in denervated samples and compared to healthy nerve. Nonparametric smoothing linear regression was implemented to better visualise trends in the expression of these markers across denervated samples. It was found, first, that two major genes associated with repair Schwann cells in rodents, c-Jun and p75NTR, are also up-regulated in acutely injured human nerves, while the myelin associated transcription factor EGR2 is down-regulated, observations that encourage the view that rodent models are relevant for learning about human nerve injury. Second, as in rodents, the expression of c-Jun and p75NTR declines during long-term denervation. In rodents, diminishing c-Jun and p75NTR levels mark the general deterioration of repair cells during chronic denervation, a process thought to be a major obstacle to effective nerve repair. The down-regulation of c-Jun and p75NTR reported here provides the first molecular evidence that also in humans, repair cells deteriorate during chronic denervation

Alberto Sampaio: subsídios para uma bibliografia

No ciclo Pensar os Pensadores, levado a cabo em 1991 pela Sociedade Martins Sarmento para comemorar o centenário da morte de Antero de Quental e o sesquicentenário do nascimento de Alberto Sampaio, esteve integrada uma Exposição Bibliográfica sobre essas duas grandes figuras da cultura portuguesa. Organizada pela Biblioteca Pública de Braga, essa exposição, além das obras cedidas por esta biblioteca, contou com algumas preciosas espécies pertença da própria Sociedade