526 research outputs found
Polynomial growth of volume of balls for zero-entropy geodesic systems
The aim of this paper is to state and prove polynomial analogues of the
classical Manning inequality relating the topological entropy of a geodesic
flow with the growth rate of the volume of balls in the universal covering. To
this aim we use two numerical conjugacy invariants, the {\em strong polynomial
entropy } and the {\em weak polynomial entropy }. Both are
infinite when the topological entropy is positive and they satisfy
. We first prove that the growth rate of the volume of
balls is bounded above by means of the strong polynomial entropy and we show
that for the flat torus this inequality becomes an equality. We then study the
explicit example of the torus of revolution for which we can give an exact
asymptotic equivalent of the growth rate of volume of balls, which we relate to
the weak polynomial entropy.Comment: 22 page
Quaternary coastal uplift along the Talara Arc (Ecuador, Northern Peru) from new marine terrace data
Marine Geology, v. 228, n. 1-4, p. 73-91, 2006. http://dx.doi.org/10.1016/j.margeo.2006.01.004International audienceMarine terrace sequences have been investigated along the Talara Arc, a 1000-km-long stretch of the coast of Ecuador and northern Peru, characterized by subduction with a concave plan-view. Seven areas were investigated, evidencing flights of up to seven marine terraces with elevations reaching up to 360 m above mean sea level (amsl). Dating of the terraces was made using the Infra Red Stimulated Luminescence (IRSL) technique on sands as old as MIS 9 (∼330 ka). 14 C and U-series dates were obtained from fossil shells for geochronological cross control. Mean uplift rates along the Talara Arc range from about 0.10 up to 0.50 mm/ yr. The strongest uplift is observed in the Manta Peninsula of Ecuador in front of the subduction of the Carnegie Ridge. The uplift rate tends to slow down towards the northern and southern ends of the Talara Arc and then the transition toward the stable or subsiding coasts of central Peru and northern Ecuador and Colombia is sharp. The uplift appears to be homogeneous and related to 1) the map view curvature of the Arc, 2) the concave subduction pattern and 3) the Carnegie Ridge subduction
Ice-sheet melt drove methane emissions in the Arctic during the last two interglacials
Circum-Arctic glacial ice is melting in an unprecedented mode, and release of currently trapped geological methane may act as a positive feedback on ice-sheet retreat during global warming. Evidence for methane release during the penultimate (Eemian, ca. 125 ka) interglacial, a period with less glacial sea ice and higher temperatures than today, is currently absent. Here, we argue that based on foraminiferal isotope studies on drill holes from offshore Svalbard, Norway, methane leakage occurred upon the abrupt Eurasian ice-sheet wastage during terminations of the last (Weichselian) and penultimate (Saalian) glaciations. Progressive increase of methane emissions seems to be first recorded by depleted benthic foraminiferal δ13C. This is quickly followed by the precipitation of methane-derived authigenic carbonate as overgrowth inside and outside foraminiferal shells, characterized by heavy δ18O and depleted δ13C of both benthic and planktonic foraminifera. The similarities between the events observed over both terminations advocate for a common driver for the episodic release of geological methane stocks. Our favored model is recurrent leakage of shallow gas reservoirs below the gas hydrate stability zone along the margin of western Svalbard that can be reactivated upon initial instability of the grounded, marine-based ice sheets. Analogous to this model, with the current acceleration of the Greenland ice melt, instabilities of existing methane reservoirs below and nearby the ice sheet are likely
Declining water resources in response to global warming and changes in atmospheric circulation patterns over southern Mediterranean France
Warming trends are responsible for an observed decrease
of water discharge in southern France (northwestern Mediterranean). Ongoing
climate change and the likely increase of water demand threaten the
availability of water resources over the coming decades. Drought indices
like the Reconnaissance Drought Index (RDI) are increasingly used in climate
characterization studies, but little is known about the relationships
between these indices, water resources, and the overall atmospheric
circulation patterns. In this study, we investigate the relationships
between the RDI, water discharge, and four atmospheric
teleconnection patterns (TPs) for six coastal river basins in southern
France, both for the historical period of the last 60 years and for a
worst-case climatic scenario (RCP8.5) reaching the year 2100. We combine
global and regional climate model (CGM and RCM, respectively) outputs with a
set of observed climatic and hydrological data in order to investigate the
past relationships between the RDI, water discharge, and TPs and to project their
potential evolution in space and time. Results indicate that annual water
discharge can be reduced by −49 % to −88 % by the end of the century under the
extreme climate scenario conditions. Due to unequal links with TPs, the
hydroclimatic evolution is unevenly distributed within the study area.
Indeed a clustering analysis performed with the RDI time series detects two
major climate clusters, separating the eastern and western part of the study
region. The former indicates stronger relationships with the Atlantic TPs
(e.g. the North Atlantic Oscillation (NAO) and the
Scandinavian Oscillation (Scand) patterns), whereas the latter is more closely
related to the Mediterranean TPs (Mediterranean Oscillation (MO) and Western Mediterranean Oscillation (WeMO)). The future climate
simulations predict an antagonistic evolution in both clusters which are
likely driven by decreasing trends of Scand and WeMO. The former provokes a
general tendency of lower P in both clusters during spring, summer, and
autumn, whereas the latter might partly compensate for this evolution by
enhanced precipitation in the eastern cluster during autumn and winter.
However, compared to observations, representation of the Mediterranean TPs
WeMO and MO in the considered climate models is less satisfactory compared
to the Atlantic TPs NAO and Scand, and further improvement of the model
simulations therefore requires better representations of the Mediterranean
TPs.</p
Frustrated Phagocytosis on Micro-Patterned Immune Complexes to Characterize Lysosome Movements in Live Macrophages
Lysosome mobilization is a key cellular process in phagocytes for bactericidal activities and trans-matrix migration. The molecular mechanisms that regulate lysosome mobilization are still poorly known. Lysosomes are hard to track as they move toward phagosomes throughout the cell volume. In order to anticipate cell regions where lysosomes are recruited to, human and RAW264.7 macrophages were seeded on surfaces that were micro-patterned with immune complexes (ICs) as 4 μm-side squares. Distances between IC patterns were adapted to optimize cell spreading in order to constrain lysosome movements mostly in two dimensions. FcΓ receptors triggered local frustrated phagocytosis, frustrated phagosomes appeared as rings of F-actin dots around the IC patterns as early as 5 min after cells made contact with the substratum. Frustrated phagosomes recruited actin-associated proteins (vinculin, paxillin, and gelsolin). The fusion of lysosomes with frustrated phagosomes was shown by the release of beta-hexosaminidase and the recruitment of Lamp1 to frustrated phagosomes. Lysosomes of RAW264.7 macrophages were labeled with cathepsin-D-mCherry to visualize their movements toward frustrated phagosomes. Lysosomes saltatory movements were markedly slowed down compared to cells layered on non-opsonized patterns. In addition, the linearity of the trajectories and the frequency and duration of contacts of lysosomes with frustrated phagosomes were measured. Our experimental set-up is the first step toward deciphering molecular mechanisms which are involved in lysosome movements in the cytoplasm (speed, directionality, and interaction with phagosomes), and opens the door to approaches such as RNA interference, pharmacological inhibition, or mutant expression
Widening of Hydrous Shear Zones During Incipient Eclogitization of Metastable Dry and Rigid Lower Crust— Holsnøy, Western Norway
The partially eclogitized crustal rocks on Holsnøy in the Bergen Arcs, Norway, indicate
that eclogitization is caused by the interplay of brittle and ductile deformation promoted by fluid
infiltration and fluid-rock interaction. Eclogitization generated an interconnected network of millimeterto-
kilometer-wide hydrous eclogite-facies shear zones, which presumably caused transient weakening
of the mechanically strong lower crust. To decipher the development of those networks, we combine
detailed lithological and structural mapping of two key outcrops with numerical modeling. Both outcrops
are largely composed of preserved granulite with minor eclogite-facies shear zones, thus representing the
beginning phases of eclogitization and ductile deformation. We suggest that deformation promoted fluidrock
interaction and eclogitization, which gradually consumed the granulite until fluid-induced reactions
were no longer significant. The shear zones widen during progressive deformation. To identify the key
parameters that impact shear zone widening, we generated scale-independent numerical models, which
focus on different processes affecting the shear zone evolution: (i) rotation of the shear zones caused
by finite deformation, (ii) mechanical weakening due to a limited amount of available fluid, and (iii)
weakening and further hydration of the shear zones as a result of continuous and unlimited fluid supply.
A continuous diffusion-type fluid infiltration, with an effective diffusion coefficient around
2
10 16 m
s
D ,
coupled with deformation is prone to develop structures similar to the ones mapped in field. Our results
suggest that the shear zones formed under a continuous fluid supply, causing shear zone widening, rather
than localization, during progressive deformation
Student use of Brühl Boulevard Chemnitz
Diese Bachelor Arbeit, soll durch die genaue Betrachtung des Standortumfeldes (insbesondere des Brühl Boulevards), die Auseinandersetzung mit der Zielgruppe Studenten und der Identifikation möglicher Investoren Anregungen, den Verkauf des Gebäudes August-Bebel Str. 11 -13 betreffend, geben
Phenotypic covariance of longevity, immunity and stress resistance in the Caenorhabditis nematodes
Background \ud
Ageing, immunity and stresstolerance are inherent characteristics of all organisms. In animals, these traits are regulated, at least in part, by forkhead transcription factors in response to upstream signals from the Insulin/Insulin– like growth factor signalling (IIS) pathway. In the nematode Caenorhabditis elegans, these phenotypes are molecularly linked such that activation of the forkhead transcription factor DAF-16 both extends lifespan and simultaneously increases immunity and stress resistance. It is known that lifespan varies significantly among the Caenorhabditis species but, although DAF-16 signalling is highly conserved, it is unclear whether this phenotypic linkage occurs in other species. Here we investigate this phenotypic covariance by comparing longevity, stress resistance and immunity in four \ud
Caenorhabditis species. \ud
\ud
Methodology/Principal Findings \ud
We show using phenotypic analysis of DAF-16 influenced phenotypes that among four closely related Caenorhabditis nematodes, the gonochoristic species (Caenorhabditis remanei and Caenorhabditis brenneri) have diverged \ud
significantly with a longer lifespan, improved stress resistance and higher immunity than the hermaphroditic species (C. elegans and Caenorhabditis briggsae). Interestingly, we also observe significant differences in expression levels between the daf-16 homologues in these species using Real-Time PCR, which positively correlate with the observed phenotypes. Finally, we provide additional evidence in support of a role for DAF-16 in regulating phenotypic coupling by using a combination of wildtype isolates, constitutively active daf-16 mutants and bioinformatic analysis. \ud
\ud
Conclusions \ud
The gonochoristic species display a significantly longer lifespan (p < 0.0001)and more robust immune and stress response (p<0.0001, thermal stress; p<0.01, heavy metal stress; p<0.0001, pathogenic stress) than the hermaphroditic species. Our data suggests that divergence in DAF-16 mediated phenotypes may underlie many of the differences observed between these four species of Caenorhabditis nematodes. These findings are further supported by the correlative higher daf-16 expression levels among the gonochoristic species and significantly higher lifespan, immunity and stress tolerance in the constitutively active daf-16 hermaphroditic mutants
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