1968: Caminhando e cantando e protestando e apanhando

Comme son titre l’indique, cet essai étudie 1968 en établissant des rapports entre la viepolitique et la vie culturelle. Il est organisé en deux parties. La première met en évidence les sentimentsde révolte et de protestation qui animent toute cette époque et mobilisent les peuples (en particulier lajeunesse, surtout les lycéens et les étudiants, mais pas uniquement) ; elle signale aussi que, d’une part, lavolonté de contestation n’était pas seulement politique et sociale, mas concernait également lescomportements et la vie sexuelle et que, d’autre part, la gauche qui en donnait une expression politiqueétait diverse et hétérogène. La deuxième partie se penche sur le Brésil, montrant que la culture y fut unearme de résistance et que le terrain culturel y fut l’enjeu d’un combat opposant une culture progressiste àune culture aliénée

Marcadores de disfunção endotelial em pacientes com doença vascular cerebral isquêmica aguda

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Avaliação da correção cirúrgica de hérnia inguinal pela técnica Lichtenstein : estudo retrospectivo de quatro anos no HCPA

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COPING E PADRÕES BIOLÓGICOS DE SONO EM EXPEDICIONÁRIOS ANTÁRTICOS

The objective of this study was to evaluate the variation of coping strategies and sleep patterns in 13 male naval aviation expeditioners at the beginning and end of a summer expedition to Antarctica. To investigate the coping and sleep variables, the BriefCOPE scale was used, a biological rhythm questionnaire and a sociodemographic form to control variables. Emotion-focused coping strategies of the dysfunctional type increased significantly throughout the exposure and there was no relationship between changes in sleep patterns and coping strategies between the onset and end of exposure to the environment. Attention to psychological factors in polar environments can prevent accidents in context.O objetivo deste estudo foi avaliar a variação das estratégias de coping e padrões de sono em 13 expedicionários do sexo masculino da aviação naval no início e ao final de uma expedição de verão à Antártica. Para investigar as variáveis de coping e de sono foram utilizadas a escala BriefCOPE, um questionário de ritmos biológicos e um formulário sociodemográfico para controle de variáveis. As estratégias de coping focadas na emoção do tipo disfuncional aumentaram de forma significativa ao longo da exposição e não houve relação entre as alterações nos padrões de sono e as estratégias de coping entre o início e final da exposição ao ambiente. A atenção a fatores psicológicos em ambientes polares pode prevenir acidentes no contexto

Effect of aliskiren on post-discharge outcomes among diabetic and non-diabetic patients hospitalized for heart failure: insights from the ASTRONAUT trial

Aims The objective of the Aliskiren Trial on Acute Heart Failure Outcomes (ASTRONAUT) was to determine whether aliskiren, a direct renin inhibitor, would improve post-discharge outcomes in patients with hospitalization for heart failure (HHF) with reduced ejection fraction. Pre-specified subgroup analyses suggested potential heterogeneity in post-discharge outcomes with aliskiren in patients with and without baseline diabetes mellitus (DM). Methods and results ASTRONAUT included 953 patients without DM (aliskiren 489; placebo 464) and 662 patients with DM (aliskiren 319; placebo 343) (as reported by study investigators). Study endpoints included the first occurrence of cardiovascular death or HHF within 6 and 12 months, all-cause death within 6 and 12 months, and change from baseline in N-terminal pro-B-type natriuretic peptide (NT-proBNP) at 1, 6, and 12 months. Data regarding risk of hyperkalaemia, renal impairment, and hypotension, and changes in additional serum biomarkers were collected. The effect of aliskiren on cardiovascular death or HHF within 6 months (primary endpoint) did not significantly differ by baseline DM status (P = 0.08 for interaction), but reached statistical significance at 12 months (non-DM: HR: 0.80, 95% CI: 0.64-0.99; DM: HR: 1.16, 95% CI: 0.91-1.47; P = 0.03 for interaction). Risk of 12-month all-cause death with aliskiren significantly differed by the presence of baseline DM (non-DM: HR: 0.69, 95% CI: 0.50-0.94; DM: HR: 1.64, 95% CI: 1.15-2.33; P < 0.01 for interaction). Among non-diabetics, aliskiren significantly reduced NT-proBNP through 6 months and plasma troponin I and aldosterone through 12 months, as compared to placebo. Among diabetic patients, aliskiren reduced plasma troponin I and aldosterone relative to placebo through 1 month only. There was a trend towards differing risk of post-baseline potassium ≥6 mmol/L with aliskiren by underlying DM status (non-DM: HR: 1.17, 95% CI: 0.71-1.93; DM: HR: 2.39, 95% CI: 1.30-4.42; P = 0.07 for interaction). Conclusion This pre-specified subgroup analysis from the ASTRONAUT trial generates the hypothesis that the addition of aliskiren to standard HHF therapy in non-diabetic patients is generally well-tolerated and improves post-discharge outcomes and biomarker profiles. In contrast, diabetic patients receiving aliskiren appear to have worse post-discharge outcomes. Future prospective investigations are needed to confirm potential benefits of renin inhibition in a large cohort of HHF patients without D

Penilaian Kinerja Keuangan Koperasi di Kabupaten Pelalawan

This paper describe development and financial performance of cooperative in District Pelalawan among 2007 - 2008. Studies on primary and secondary cooperative in 12 sub-districts. Method in this stady use performance measuring of productivity, efficiency, growth, liquidity, and solvability of cooperative. Productivity of cooperative in Pelalawan was highly but efficiency still low. Profit and income were highly, even liquidity of cooperative very high, and solvability was good