Unidade Técnico Funcional – Prestação de serviços : Formação Profissional de 2011 a junho de 2015.

Unidade Técnico Funcional – Prestação de serviços : Formação Profissional de 2011 a junho de 2015.info:eu-repo/semantics/publishedVersio

Universal moduli-dependent thresholds in Z(2)xZ(2) orbifolds

In the context of a recently proposed method for computing exactly string loop corrections regularized in the infra-red, we determine and calculate the universal moduli-dependent part of the threshold corrections to the gauge couplings for the symmetric $Z_2\times Z_2$ orbifold model. We show that these corrections decrease the unification scale of the underlying effective field theory. We also comment on the relation between this infra-red regularization scheme and other proposed methods.Comment: 12 pages, Latex, contains two figures, final version, typos correcte

Experimental and numerical simulations of oblique extreme wave conditions in front of a breakwater's trunk and round head

ABSTARCT: Climate change studies already reported sea level rise as an accepted scenario, which induces changes in nearshore wave conditions. A large range of new experiences including water level, run-up, overtopping, hydrodynamic data for different wave steepnesses and directions was performed in the Leibniz Universität Hannover (LUH) wave basin for a rubble mound breakwater with a slope of 1(V):2(H). This work presents, focusing on oblique extreme wave conditions, numerical simulations of the hydrodynamics in that experiment using OpenFOAM®. Results of the wave generation boundary conditions and their propagation, namely elevation of the water level free-surface and velocity data at specific locations are compared and discussed with data from experimental measurements acquired by acoustic wave gauges and acoustic doppler velocimeter (ADV) / Vectrino equipment. Although an exact match between numerical and laboratory values was not reached, an appropriate incident wave angle and a reasonable amplitude of velocities and water depths was achieved and the same happened to the statistics of those values

COMPILATION OF ACTIVE FAULT DATA IN PORTUGAL FOR USE IN SEISMIC HAZARD ANALYSIS

To estimate where future earthquakes are likely to occur, it is essential to combine information about past earthquakes with knowledge about the location and seismogenic properties of active faults. For this reason, robust probabilistic seismic hazard analysis (PSHA) integrates seismicity and active fault data. Existing seismic hazard assessments for Portugal rely exclusively on seismicity data and do not incorporate data on active faults. Project SHARE (Seismic Hazard Harmonization in Europe) is an EC-funded initiative (FP7) that aims to evaluate European seismic hazards using an integrated, standardized approach. In the context of SHARE, we are developing a fully-parameterized active fault database for Portugal that incorporates existing compilations, updated according to the most recent publications. The seismogenic source model derived for SHARE will be the first model for Portugal to include fault data and follow an internationally standardized approach. This model can be used to improve both seismic hazard and risk analyses and will be combined with the Spanish database for use in Iberian- and European-scale assessments

Abnormal hedgehog pathway in myelodysplastic syndrome and its impact on patients' outcome

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Caracterização e desempenho de filtros com nanofibras e HEPA utilizando nanopartículas

We compare the performance of a traditional HEPA filter medium with other types of filter media containing nano-fibers paying special attention to the nano-particle size range below 100 nm. We characterized all media both at micro-scale to study their fiber size distribution and at macro-scale to measure their airflow resistance and removal efficiency resolved by particle size down to a few nano-meters

Overexpression of adenosine A2A receptors in rats: effects on depression, locomotion, and anxiety

Adenosine A2A receptors (A2AR) are a sub-type of receptors enriched in basal ganglia, activated by the neuromodulator adenosine, which interact with dopamine D2 receptors. Although this reciprocal antagonistic interaction is well-established in motor function, the outcome in dopamine-related behaviors remains uncertain, in particular in depression and anxiety. We have demonstrated an upsurge of A2AR associated to aging and chronic stress. Furthermore, Alzheimer's disease patients present A2AR accumulation in cortical areas together with depressive signs. We now tested the impact of overexpressing A2AR in forebrain neurons on dopamine-related behavior, namely depression. Adult male rats overexpressing human A2AR under the control of CaMKII promoter [Tg(CaMKII-hA2AR)] and aged-matched wild-types (WT) of the same strain (Sprague-Dawley) were studied. The forced swimming test (FST), sucrose preference test (SPT), and the open-field test (OFT) were performed to evaluate behavioral despair, anhedonia, locomotion, and anxiety. Tg(CaMKII-hA2AR) animals spent more time floating and less time swimming in the FST and presented a decreased sucrose preference at 48 h in the SPT. They also covered higher distances in the OFT and spent more time in the central zone than the WT. The results indicate that Tg(CaMKII-hA2AR) rats exhibit depressive-like behavior, hyperlocomotion, and altered exploratory behavior. This A2AR overexpression may explain the depressive signs found in aging, chronic stress, and Alzheimer's disease

Double-Scaling Limit of Heterotic Bundles and Dynamical Deformation in CFT

We consider heterotic string theory on Eguchi-Hanson space, as a local model of a resolved A_1 singularity in a six-dimensional flux compactification, with an Abelian gauge bundle turned on and non-zero torsion. We show that in a suitable double scaling limit, that isolates the physics near the non-vanishing two-cycle, a worldsheet conformal field theory description can be found. It contains a heterotic coset whose target space is conformal to Eguchi-Hanson. Starting from the blow-down limit of the singularity, it can be viewed as a dynamical deformation of the near-horizon fivebrane background. We analyze in detail the spectrum of the theory in particular examples, as well as the important role of worldsheet non-perturbative effects.Comment: 45 pages, no figures; ver2: typos corrected, references added, an extra tadpole-free model covere

Effect of sequential medium on in vitro culture of goat ovarian cortical tissue

A sequential medium was evaluated on the survival, activation and growth rates of caprine preantral follicles submitted to a long-term culture period, aiming to establish an ideal in vitro culture system. Ovarian fragments were cultured for 16 days in α-MEM+ alone or supplemented with hormones (GH and/or FSH) added sequentially on different days of culture. Ovarian fragments were cultured in the first (days 0–8) and second (days 8–16) halves of the culture period, generating 10 treatments: α-MEM+/α-MEM+, FSH/FSH, FSH/GH, FSH/FSH + GH, GH/GH, GH/FSH, GH/FSH + GH, FSH + GH/FSH + GH, FSH + GH/FSH and FSH + GH/GH. Follicle morphology, viability and ultrastructure were analyzed. After day 1 of culture, FSH treatments maintained the percentage of normal follicles similar to the fresh control. At day 16 of culture, the treatment FSH/GH showed the highest (P < 0.05) percentage of normal follicles. The ultrastructure of follicles was preserved in the fresh control and FSH/GH treatment. Follicles cultured with FSH/GH had a higher (P < 0.05) viability than α-MEM+; however the viability was lower (P < 0.05) when compared to the fresh control. The FSH/GH treatment showed the highest (P < 0.05) percentage of follicular activation and secondary follicle formation and produced the largest (P < 0.05) mean follicular diameter after 16 days of culture. In conclusion, a sequential medium supplemented with FSH followed by GH during a long-term culture maintains the survival, viability and ultrastructure of goat preantral follicles, and promotes activation and secondary follicles

Moduli and (un)attractor black hole thermodynamics

We investigate four-dimensional spherically symmetric black hole solutions in gravity theories with massless, neutral scalars non-minimally coupled to gauge fields. In the non-extremal case, we explicitly show that, under the variation of the moduli, the scalar charges appear in the first law of black hole thermodynamics. In the extremal limit, the near horizon geometry is $AdS_2\times S^2$ and the entropy does not depend on the values of moduli at infinity. We discuss the attractor behaviour by using Sen's entropy function formalism as well as the effective potential approach and their relation with the results previously obtained through special geometry method. We also argue that the attractor mechanism is at the basis of the matching between the microscopic and macroscopic entropies for the extremal non-BPS Kaluza-Klein black hole.Comment: 36 pages, no figures, V2: minor changes, misprints corrected, expanded references; V3: sections 4.3 and 4.5 added; V4: minor changes, matches the published versio