The Discovery of Sgr A*

The compact radio source Sgr A* is associated with a 3.6 million black hole at the center of the Milky Way. The radio source was discovered in February 1974 by Bruce Balick and Robert L.Brown. The National Radio Astronomy Observatory's Green Bank 35 km radio link interferometer was used. We discuss other observations in the years 1965-1985 as well as early VLBI observations. The name Sgr A* was used for the first time in 1982 by Robert L.Brown and has become the accepted name in the intervening years.Comment: 8 pages,2 figures. Conference proceedings: "The central 300 parsecs of the Milky Way", editors A.Cotera, H.Falcke, T.R.Geballe, S.Markof

An unexpected twist to the activation of IKKβ:TAK1 primes IKKβ for activation by autophosphorylation

IKKβ {IκB [inhibitor of NF-κB (nuclear factor κB)] kinase β} is required to activate the transcription factor NF-κB, but how IKKβ itself is activated in vivo is still unclear. It was found to require phosphorylation by one or more ‘upstream’ protein kinases in some reports, but by autophosphorylation in others. In the present study, we resolve this contro-versy by demonstrating that the activation of IKKβ induced by IL-1 (interleukin-1) or TNF (tumour necrosis factor) in embryonic fibroblasts, or by ligands that activate Toll-like receptors in macrophages, requires two distinct phosphorylation events: first, the TAK1 [TGFβ (transforming growth factor β)-activated kinase-1]-catalysed phosphorylation of Ser(177) and, secondly, the IKKβ-catalysed autophosphorylation of Ser(181). The phosphorylation of Ser(177) by TAK1 is a priming event required for the subsequent autophosphorylation of Ser(181), which enables IKKβ to phosphorylate exogenous substrates. We also provide genetic evidence which indicates that the IL-1-stimulated, LUBAC (linear ubiquitin chain assembly complex)-catalysed formation of linear ubiquitin chains and their interaction with the NEMO (NF-κB essential modulator) component of the canonical IKK complex permits the TAK1-catalysed priming phosphorylation of IKKβ at Ser(177) and IKKα at Ser(176). These findings may be of general significance for the activation of other protein kinases

Supersonic laminar flow control research

The objective of this research is to understand supersonic laminar flow stability, transition and active control. Some prediction techniques will be developed or modified to analyze laminar flow stability. The effects of distributed heating and cooling as an active boundary layer control technique will be studied. The primary tasks of the research apply to the NASA/Ames PoC and LFSWT's nozzle design with laminar flow control and are listed as follows: (1) predictions of supersonic laminar boundary layer stability and transition; (2) effects of wall heating and cooling on supersonic laminar flow control; (3) performance evaluation of the PoC and LFSWT nozzle designs with wall heating and cooling applied at different locations and various lengths; and (4) effects of a conducted -vs- pulse wall temperature distribution for the LFSWT

Modelling network travel time reliability under stochastic demand

A technique is proposed for estimating the probability distribution of total network travel time, in the light of normal day-to-day variations in the travel demand matrix over a road traffic network. A solution method is proposed, based on a single run of a standard traffic assignment model, which operates in two stages. In stage one, moments of the total travel time distribution are computed by an analytic method, based on the multivariate moments of the link flow vector. In stage two, a flexible family of density functions is fitted to these moments. It is discussed how the resulting distribution may in practice be used to characterise unreliability. Illustrative numerical tests are reported on a simple network, where the method is seen to provide a means for identifying sensitive or vulnerable links, and for examining the impact on network reliability of changes to link capacities. Computational considerations for large networks, and directions for further research, are discussed

Risk and risk management in the credit card industry

Using account-level credit card data from six major commercial banks from January 2009 to December 2013, we apply machine-learning techniques to combined consumer tradeline, credit bureau, and macroeconomic variables to predict delinquency. In addition to providing accurate measures of loss probabilities and credit risk, our models can also be used to analyze and compare risk management practices and the drivers of delinquency across banks. We find substantial heterogeneity in risk factors, sensitivities, and predictability of delinquency across banks, implying that no single model applies to all six institutions. We measure the efficacy of a bank's risk management process by the percentage of delinquent accounts that a bank manages effectively, and find that efficacy also varies widely across institutions. These results suggest the need for a more customized approached to the supervision and regulation of financial institutions, in which capital ratios, loss reserves, and other parameters are specified individually for each institution according to its credit risk model exposures and forecasts

The groupoid approach to Leavitt path algebras

When the theory of Leavitt path algebras was already quite advanced, it was discovered that some of the more difficult questions were susceptible to a new approach using topological groupoids. The main result that makes this possible is that the Leavitt path algebra of a graph is graded isomorphic to the Steinberg algebra of the graph’s boundary path groupoid. This expository paper has three parts: Part 1 is on the Steinberg algebra of a groupoid, Part 2 is on the path space and boundary path groupoid of a graph, and Part 3 is on the Leavitt path algebra of a graph. It is a self-contained reference on these topics, intended to be useful to beginners and experts alike. While revisiting the fundamentals, we prove some results in greater generality than can be found elsewhere, including the uniqueness theorems for Leavitt path algebras

Superconducting Analogues of Quantum Optical Phenomena: Macroscopic Quantum Superpositions and Squeezing in a SQUID Ring

In this paper we explore the quantum behaviour of a SQUID ring which has a significant Josephson coupling energy. We show that that the eigenfunctions of the Hamiltonian for the ring can be used to create macroscopic quantum superposition states of the ring. We also show that the ring potential may be utilised to squeeze coherent states. With the SQUID ring as a strong contender as a device for manipulating quantum information, such properties may be of great utility in the future. However, as with all candidate systems for quantum technologies, decoherence is a fundamental problem. In this paper we apply an open systems approach to model the effect of coupling a quantum mechanical SQUID ring to a thermal bath. We use this model to demonstrate the manner in which decoherence affects the quantum states of the ring.Comment: 9 pages, 10 figures, To be submitted to Phys. Rev. A. (changes for referee's and editior's comments - replaced to try to get PDF working

Waiting times between orders and trades in double-auction markets

In this paper, the survival function of waiting times between orders and the corresponding trades in a double-auction market is studied both by means of experiments and of empirical data. It turns out that, already at the level of order durations, the survival function cannot be represented by a single exponential, thus ruling out the hypothesis of constant activity during trading. This fact has direct consequences for market microstructural models. They must include such a non-exponential behaviour to be realistic.Comment: 19 pages, 3 figures, paper presented at the WEHIA 2005, Colchester, U

\'Etale groupoids and Steinberg algebras, a concise introduction

We give a concise introduction to (discrete) algebras arising from \'etale groupoids, (aka Steinberg algebras) and describe their close relationship with groupoid C*-algebras. Their connection to partial group rings via inverse semigroups also explored

Energy Down Conversion between Classical Electromagnetic Fields via a Quantum Mechanical SQUID Ring

We consider the interaction of a quantum mechanical SQUID ring with a classical resonator (a parallel $LC$ tank circuit). In our model we assume that the evolution of the ring maintains its quantum mechanical nature, even though the circuit to which it is coupled is treated classically. We show that when the SQUID ring is driven by a classical monochromatic microwave source, energy can be transferred between this input and the tank circuit, even when the frequency ratio between them is very large. Essentially, these calculations deal with the coupling between a single macroscopic quantum object (the SQUID ring) and a classical circuit measurement device where due account is taken of the non-perturbative behaviour of the ring and the concomitant non-linear interaction of the ring with this device.Comment: 7 pages, 6 figure