Estimated surgical requirements in England after COVID-19: a modelling study using hospital episode statistics

A statistical analysis plan using aggregated, publicly available data from NHS Digital and NHS England to model disruption to, and resources associated with re-establishing, surgical care during the COVID-19 pandemic

Twelve Tips for Medical Students starting Clinical Placements in the United Kingdom

Transitioning from the pre-clinical to clinical years at medical school can be challenging and overwhelming. This paper aims to utilise the experience of healthcare professionals to provide tips for medical students to consider in order to maximise their learning opportunities. Before starting a placement, it is highly encouraged that you familiarise yourself with the curriculum, remember to bring your essentials and dress appropriately. During your placement, ensure good attendance keeping, introduce yourself to the team, manage your time well, engage in self-directed learning, ask questions to other doctors, interact with allied health care professionals and follow the patient’s journey from admission to discharge. It is also key to be wary of university requirements, regularly practice history-taking and clinical examination and examination style questions. Prioritise a suitable work-life balance by enjoying hobbies and extra-curricular activities in order to avoid burn-out. These tips should ensure medical students make the most of their clinical placements as well as making it a memorable and enjoyable experience

Imaging assessment of children presenting with suspected or known juvenile idiopathic arthritis : ESSR-ESPR points to consider

Juvenile idiopathic arthritis (JIA) is the most common paediatric rheumatic disease. It represents a group of heterogenous inflammatory disorders with unknown origin and is a diagnosis of exclusion in which imaging plays an important role. JIA is defined as arthritis of one or more joints that begins before the age of 16 years, persists for more than 6 weeks and is of unknown aetiology and pathophysiology. The clinical goal is early suppression of inflammation to prevent irreversible joint damage which has shifted the emphasis from detecting established joint damage to proactively detecting inflammatory change. This drives the need for imaging techniques that are more sensitive than conventional radiography in the evaluation of inflammatory processes as well as early osteochondral change. Physical examination has limited reliability, even if performed by an experienced clinician, emphasising the importance of imaging to aid in clinical decision-making. On behalf of the European Society of Musculoskeletal Radiology (ESSR) arthritis subcommittee and the European Society of Paediatric Radiology (ESPR) musculoskeletal imaging taskforce, based on literature review and/or expert opinion, we discuss paediatric-specific imaging characteristics of the most commonly involved, in literature best documented and clinically important joints in JIA, namely the temporomandibular joints (TMJs), spine, sacroiliac (SI) joints, wrists, hips and knees, followed by a clinically applicable point to consider for each joint. We will also touch upon controversies in the current literature that remain to be resolved with ongoing research

Multifunctional tribometer development and performance study of CuCrZr-316L material pair for ITER application

Radio-Frequency (RF) contacts are key components on the International Thermonuclear Experimental Reactor (ITER) Ion Cyclotron Resonance Heating (ICRH) antenna, and these components are facing big challenges such as 2 kA operation current load and intensive sliding under up to 250 °C in high vacuum. Stainless steel (SS) 316L and CuCrZr are most likely to be applied as base materials for the conductor and the RF contacts louvers. To evaluate the performance of the selected materials, their electrical and tribological behaviors have to be studied. A multifunctional tribometer which can mimic the ITER ICRH RF contacts' relevant working conditions was designed and built in CEA. The contact resistance (Rc) and coefficient of friction (CoF) of CuCrZr-316L pair were researched on this tribometer

The HOG Pathway Dictates the Short-Term Translational Response after Hyperosmotic Shock

In the global osmoshock translational response in yeast, some gene products were translationally mobilized without transcriptional up-regulation. Conversely, other transcriptionally up-regulated mRNAs were translationally inhibited. Analogous changes occurred on the protein level. These translational responses were strongly dependent on Hog1 and Rck2

Recent advances in ankylosing spondylitis: understanding the disease and management

The term spondyloarthritis refers to a group of immune-mediated diseases characterised by inflammation of the axial skeleton, peripheral joints, and entheses. Ankylosing spondylitis (AS) is the most common and characteristic of these entities and even though it was first described over two centuries ago, the understanding of the underlying disease mechanism remains incomplete. It is known that around 40% of patients with AS have subclinical bowel inflammation, suggesting that the origin of the disease could be in the gut. Also, more genes and new molecules have demonstrated a role in the pathogenesis of AS. In this review, we analyse the latest therapies for spondyloarthritis and the most relevant discoveries over the last three years, together with their implications for different aspects of the disease

The impact of leadership on the psychosocial safety climate of organizations: A scoping review

Growing evidence suggests that work-related psychological injuries are a concern worldwide. While previous efforts to address psychological injuries mainly focused on the individual level of analysis, the psychosocial safety climate (PSC) theory emphasizes the analysis and prevention of psychological injuries at the organizational level. While there is abundant evidence of the impact of leadership on other climate constructs, scant attention has been paid to the impact of leadership on PSC. This study is a scoping review of the extant literature to determine the state of the discipline in relation to the impact of leadership on the psychosocial safety climate of organizations. Three databases were searched, supplemented by a pearling exercise and Google Scholar searches, which yielded 14 studies that met the selection criteria. Our study shows that while much work has been done about the behavior of managers and organizational infrastructure to yield high levels of PSC, there is a dearth of studies on the impact of specific leadership styles on the PSC of organizations. We recommend further studies of leadership, especially the impact of post-heroic leadership styles, on the psychosocial safety climate of workplaces