Decision support systems: A growing improvement in a company in the national electricity sector

A função do Sistema de Apoio à Decisão (SAD) é compilar informações de todos os setores e apresentar uma forma organizada, resumida e direta das informações corporativas, com o intuito de auxiliar, agilizar e maximizar a tomada de decisão dos gestores e colaboradores. Esta pesquisa teve como objetivo analisar as evoluções dos SADs ocorridas no período de dez anos na empresa ELETROBRAS. Para alcançar o objetivo proposto foi realizada uma pesquisa de campo, sendo os dados coletados em documentos fornecidos pela empresa, no sítio eletrônico oficial e por meio de entrevistas semiestruturadas. Os resultados da pesquisa demonstram que a ELETROBRAS passou por uma grande transformação ao iniciar um processo de unificação de todos os seus SADs por meio da implementação de um ERP (Enterprise Resource Planning), que passou a ser o maior insumo das informações corporativas ao sistema de apoio à decisão. Essa evolução foi necessária e fundamental para a integração das informações das empresas que fazem parte do grupo ELETROBRAS, melhorar o processo de tomada de decisão e para obter maior confiabilidade dos acionistas. Foi possível ainda verificar que, apesar dos aspectos negativos apontados pelos entrevistados, os benefícios da concretização dessa implantação se sobrepuseram aos desafios.info:eu-repo/semantics/publishedVersio

Flowing Between Fermionic Fixed Points

We study holographic Wilsonian renormalization group flows for bulk spinor fields in AdS. We use this to compute the all-loop beta function for fermionic double trace operators in the dual conformal field theory.Comment: 21 pages. V2: Acknowledgement added; v3: Typo correcte

Virulence and selection of Beauveria bassiana for the control of Thaumastocoris eregrinus.

This work aimed to assess the virulence of Beauveria bassiana isolates in different concentrations on Thaumastocoris peregrinus (Hemiptera, Thaumastocoridae) and select them to control this insect pest. Suspensions of IBCB35, IBCB66, IBCB18, IBCB01 and JAB06 isolates were tested in the concentrations of zero, 1 × 104, 1 × 106, 1 × 108 conidia/ml, applied on the eucalyptus leaves used to feed the insects. Dead insects were disinfested daily and placed in a humid chamber to confirm the death by fungus. Mortality at the end of the experiment ranged from 12% for IBCB66 to 48% for IBCB18 at a concentration of 1 × 104 conidia/ml, between 32% for IBCB66 and 68% for JAB06 at a concentration of 1 × 106 conidia/ml, and between 60% for IBCB01 and 84% for JAB06 at the concentration 1 × 108 conidia/ml. The assessed isolates were efficient in controlling the insect, especially JAB06

Molecular portrait of high alpha-fetoprotein in hepatocellular carcinoma: implications for biomarker-driven clinical trials

The clinical utility of serum alpha-fetoprotein (AFP) in patients with hepatocellular carcinoma (HCC) is widely recognised. However, a clear understanding of the mechanisms of AFP overexpression and the molecular traits of patients with AFP-high tumours are not known. We assessed transcriptome data, whole-exome sequencing data and DNA methylome profiling of 520 HCC patients from two independent cohorts to identify distinct molecular traits of patients with AFP-high tumours (serum concentration?>?400?ng/ml), which represents an accepted prognostic cut-off and a predictor of response to ramucirumab. Those AFP-high tumours (18% of resected cases) were characterised by significantly lower AFP promoter methylation (p?<?0.001), significant enrichment of progenitor-cell features (CK19, EPCAM), higher incidence of BAP1 oncogene mutations (8.5% vs 1.6%) and lower mutational rates of CTNNB1 (14% vs 30%). Specifically, AFP-high tumours displayed significant activation of VEGF signalling (p?<?0.001), which might provide the rationale for the reported benefit of ramucirumab in this subgroup of patients

Socioeconomic inequalities in suicide mortality in European urban areas before and during the economic recession

Few studies have assessed the impact of the financial crisis on inequalities in suicide mortality in European urban areas. The objective of the study was to analyse the trend in area socioeconomic inequalities in suicide mortality in nine European urban areas before and after the beginning of the financial crisis. This ecological study of trends was based on three periods, two before the economic crisis (2000-2003, 2004-2008) and one during the crisis (2009-2014). The units of analysis were the small areas of nine European cities or metropolitan areas, with a median population ranging from 271 (Turin) to 193 630 (Berlin). For each small area and sex, we analysed smoothed standardized mortality ratios of suicide mortality and their relationship with a socioeconomic deprivation index using a hierarchical Bayesian model. Among men, the relative risk (RR) comparing suicide mortality of the 95th percentile value of socioeconomic deprivation (severe deprivation) to its 5th percentile value (low deprivation) were higher than 1 in Stockholm and Lisbon in the three periods. In Barcelona, the RR was 2.06 (95% credible interval: 1.24-3.21) in the first period, decreasing in the other periods. No significant changes were observed across the periods. Among women, a positive significant association was identified only in Stockholm (RR around 2 in the three periods). There were no significant changes across the periods except in London with a RR of 0.49 (95% CI: 0.35-0.68) in the third period. Area socioeconomic inequalities in suicide mortality did not change significantly after the onset of the crisis in the areas studied

Association between canine leishmaniosis and Ehrlichia canis co-infection: a prospective case-control study

Abstract Background In the Mediterranean basin, Leishmania infantum is a major cause of disease in dogs, which are frequently co-infected with other vector-borne pathogens (VBP). However, the associations between dogs with clinical leishmaniosis (ClinL) and VBP co-infections have not been studied. We assessed the risk of VBP infections in dogs with ClinL and healthy controls. Methods We conducted a prospective case-control study of dogs with ClinL (positive qPCR and ELISA antibody for L. infantum on peripheral blood) and clinically healthy, ideally breed-, sex- and age-matched, control dogs (negative qPCR and ELISA antibody for L. infantum on peripheral blood) from Paphos, Cyprus. We obtained demographic data and all dogs underwent PCR on EDTA-blood extracted DNA for haemoplasma species, Ehrlichia/Anaplasma spp., Babesia spp., and Hepatozoon spp., with DNA sequencing to identify infecting species. We used logistic regression analysis and structural equation modelling (SEM) to evaluate the risk of VBP infections between ClinL cases and controls. Results From the 50 enrolled dogs with ClinL, DNA was detected in 24 (48%) for Hepatozoon spp., 14 (28%) for Mycoplasma haemocanis, 6 (12%) for Ehrlichia canis and 2 (4%) for Anaplasma platys. In the 92 enrolled control dogs, DNA was detected in 41 (45%) for Hepatozoon spp., 18 (20%) for M. haemocanis, 1 (1%) for E. canis and 3 (3%) for A. platys. No Babesia spp. or “Candidatus Mycoplasma haematoparvum” DNA was detected in any dog. No statistical differences were found between the ClinL and controls regarding age, sex, breed, lifestyle and use of ectoparasitic prevention. A significant association between ClinL and E. canis infection (OR = 12.4, 95% CI: 1.5–106.0, P = 0.022) was found compared to controls by multivariate logistic regression. This association was confirmed using SEM, which further identified that younger dogs were more likely to be infected with each of Hepatozoon spp. and M. haemocanis, and dogs with Hepatozoon spp. were more likely to be co-infected with M. haemocanis. Conclusions Dogs with ClinL are at a higher risk of co-infection with E. canis than clinically healthy dogs. We recommend that dogs diagnosed with ClinL should be tested for E. canis co-infection using PCR

Dipole Coupling Effect of Holographic Fermion in the Background of Charged Gauss-Bonnet AdS Black Hole

We investigate the holographic fermions in the charged Gauss-Bonnet $AdS_{d}$ black hole background with the dipole coupling between fermion and gauge field in the bulk. We show that in addition to the strength of the dipole coupling, the spacetime dimension and the higher curvature correction in the gravity background also influence the onset of the Fermi gap and the gap distance. We find that the higher curvature effect modifies the fermion spectral density and influences the value of the Fermi momentum for the appearance of the Fermi surface. There are richer physics in the boundary fermion system due to the modification in the bulk gravity.Comment: 16 pages, accepted for publication in JHE

Acute febrile illness is associated with Rickettsia spp infection in dogs

BACKGROUND: Rickettsia conorii is transmitted by Rhipicephalus sanguineus ticks and causes Mediterranean Spotted Fever (MSF) in humans. Although dogs are considered the natural host of the vector, the clinical and epidemiological significance of R. conorii infection in dogs remains unclear. The aim of this prospective study was to investigate whether Rickettsia infection causes febrile illness in dogs living in areas endemic for human MSF. METHODS: Dogs from southern Italy with acute fever (n = 99) were compared with case–control dogs with normal body temperatures (n = 72). Serology and real-time PCR were performed for Rickettsia spp., Ehrlichia canis, Anaplasma phagocytophilum/A. platys and Leishmania infantum. Conventional PCR was performed for Babesia spp. and Hepatozoon spp. Acute and convalescent antibodies to R. conorii, E. canis and A. phagocytophilum were determined. RESULTS: The seroprevalence rates at first visit for R. conorii, E. canis, A. phagocytophilum and L. infantum were 44.8%, 48.5%, 37.8% and 17.6%, respectively. The seroconversion rates for R. conorii, E. canis and A. phagocytophilum were 20.7%, 14.3% and 8.8%, respectively. The molecular positive rates at first visit for Rickettsia spp., E. canis, A. phagocytophilum, A. platys, L. infantum, Babesia spp. and Hepatozoon spp. were 1.8%, 4.1%, 0%, 2.3%, 11.1%, 2.3% and 0.6%, respectively. Positive PCR for E. canis (7%), Rickettsia spp. (3%), Babesia spp. (4.0%) and Hepatozoon spp. (1.0%) were found only in febrile dogs. The DNA sequences obtained from Rickettsia and Babesia PCRs positive samples were 100% identical to the R. conorii and Babesia vogeli sequences in GenBank®, respectively. Febrile illness was statistically associated with acute and convalescent positive R. conorii antibodies, seroconversion to R. conorii, E. canis positive PCR, and positivity to any tick pathogen PCRs. Fourteen febrile dogs (31.8%) were diagnosed with Rickettsia spp. infection based on seroconversion and/or PCR while only six afebrile dogs (12.5%) seroconverted (P = 0.0248). The most common clinical findings of dogs with Rickettsia infection diagnosed by seroconversion and/or PCR were fever, myalgia, lameness, elevation of C-reactive protein, thrombocytopenia and hypoalbuminemia. CONCLUSIONS: This study demonstrates acute febrile illness associated with Rickettsia infection in dogs living in endemic areas of human MSF based on seroconversion alone or in combination with PCR

TOIMINNANOHJAUSJÄRJESTELMÄN KÄYTTÖÖNOTON VAIKUTUS

Tässä tutkielmassa tutkitaan kuinka toiminnanohjausjärjestelmän käyttöönotto on vaikuttanut yrityksen tulokseen ja suorituskykyyn suomalaisissa yrityksissä 1999-2015. Tavoitteena on testata empiirisesti aiheuttaako toiminnanohjausjärjestelmän käyttöönotto merkittäviä säästöjä, yrityk-sen toiminnan tehokkuuden parannuksia ja muutoksia yrityksen kannattavuudessa. Toiminnanohjaus- eli ERP-järjestelmät integroivat yrityksen eri toimintoja esimerkiksi logistiikkaa, tuotantoa, kirjanpitoa, varastointia ja laskutusta yhteen järjestelmään ja näin ollen tehostavat yrityksen toimintaa useiden eri järjestelmien käytön sijaan. Onkin tärkeää selvittää kuinka toiminnanohjausjärjestelmien käyttöönotto on vaikuttanut yritysten kannattavuuteen ja voidaanko investointi nähdä tuottavana. Aikaisempien tutkimusten perusteella tulokset ovat ristiriitaisia; tutkimukset osoittavat, että vaikka ERP- järjestelmien käyttöönotto tutkitusti vaikuttaa ei-rahamääräisiin mittareihin, vaikutusta rahamääräisiin mittareihin ei aina pystytä todistamaan. Yritysten kannalta mielenkiintoista onkin ovatko kalliit ERP-järjestelmät, sekä niiden implementointiprosessit todella kannattavia investointeja. Tutkimuksen empiirisessä osiossa selvitettiin toiminnanohjausjärjestelmien käyttöönoton vaiku-tuksia suorituskykyyn suomalaisissa yhtiöissä, jotka ovat implementoineet toiminnanohjausjärjestelmän vuosina 1999-2015. Aineistona on käytetty julkisuudessa ilmoitettuja järjestelmähank-keita sekä tilinpäätöstietoja implementointiprosessin jälkeisiltä sekä edeltäviltä vuosilta. Suorituskyvyn muutosta on seurattu vertailemalla suorituskyvyn ja kannattavuuden muutosta implementoinnin jälkeen. Tutkimus on suoritettu määrällisenä tutkimuksena ja tilastollisina menetelminä on käytetty toistomittausten varianssianalyysiä sekä t-testiä parivertailulle. Tutkimuksessa havaittiin, että näyttäisi siltä, ettei toiminnanohjausjärjestelmien käyttöönotolla ei ole ollut vaikutusta kohdeyhtiöiden rahamääräiseen suorituskykyyn.fi=Opinnäytetyö kokotekstinä PDF-muodossa.|en=Thesis fulltext in PDF format.|sv=Lärdomsprov tillgängligt som fulltext i PDF-format