2,225 research outputs found

    A review of the use of information and communication technologies for dietary assessment

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    Presently used dietary-assessment methods often present difficulties for researchers and respondents, and misreporting errors are common. Methods using information and communication technologies (ICT) may improve quality and accuracy. The present paper presents a systematic literature review describing studies applying ICT to dietary assessment. Eligible papers published between January 1995 and February 2008 were classified into four assessment categories: computerised assessment; personal digital assistants (PDA); digital photography; smart cards. Computerised assessments comprise frequency questionnaires, 24 h recalls (24HR) and diet history assessments. Self-administered computerised assessments, which can include audio support, may reduce literacy problems, be translated and are useful for younger age groups, but less so for those unfamiliar with computers. Self-administered 24HR utilising computers yielded comparable results as standard methods, but needed supervision if used in children. Computer-assisted interviewer-administered recall results were similar to conventional recalls, and reduced inter-interviewer variability. PDA showed some advantages but did not reduce underreporting. Mobile phone meal photos did not improve PDA accuracy. Digital photography for assessing individual food intake in dining facilities was accurate for adults and children, although validity was slightly higher with direct visual observation. Smart cards in dining facilities were useful for measuring food choice but not total dietary intake. In conclusion, computerised assessments and PDA are promising, and could improve dietary assessment quality in some vulnerable groups and decrease researcher workload. Both still need comprehensive evaluation for micronutrient intake assessment. Further work is necessary for improving ICT tools in established and new methods and for their rigorous evaluatio

    Single-mask thermal displacement sensor in MEMS

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    In this work we describe a one degree-of-freedom microelectromechanical thermal\ud displacement sensor integrated with an actuated stage. The system was fabricated in the device layer of a silicon-on-insulator wafer using a single-mask process. The sensor is based on the temperature dependent electrical resistivity of silicon and the heat transfer by conduction through a thin layer of air. On a measurement range of 50 μm and using a measurement bandwidth of 30 Hz, the 1-sigma noise corresponds to 3.47 nm. The power consumption of the sensor is 209 mW, almost completely independent of stage position. The drift of the sensor over a measurement period of 32 hours was 32 nm

    Phase of beta-frequency tACS over primary motor cortex modulates corticospinal excitability

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    The assessment of corticospinal excitability by means of transcranial magnetic stimulation-induced motor evoked potentials is an established diagnostic tool in neurophysiology and a widely used procedure in fundamental brain research. However, concern about low reliability of these measures has grown recently. One possible cause of high variability of MEPs under identical acquisition conditions could be the influence of oscillatory neuronal activity on corticospinal excitability. Based on research showing that transcranial alternating current stimulation can entrain neuronal oscillations we here test whether alpha or beta frequency tACS can influence corticospinal excitability in a phase-dependent manner. We applied tACS at individually calibrated alpha- and beta-band oscillation frequencies, or we applied sham tACS. Simultaneous single TMS pulses time locked to eight equidistant phases of the ongoing tACS signal evoked MEPs. To evaluate offline effects of stimulation frequency, MEP amplitudes were measured before and after tACS. To evaluate whether tACS influences MEP amplitude, we fitted one-cycle sinusoids to the average MEPs elicited at the different phase conditions of each tACS frequency. We found no frequency-specific offline effects of tACS. However, beta-frequency tACS modulation of MEPs was phase-dependent. Post hoc analyses suggested that this effect was specific to participants with low (<19 Hz) intrinsic beta frequency. In conclusion, by showing that beta tACS influences MEP amplitude in a phase-dependent manner, our results support a potential role attributed to neuronal oscillations in regulating corticospinal excitability. Moreover, our findings may be useful for the development of TMS protocols that improve the reliability of MEPs as a meaningful tool for research applications or for clinical monitoring and diagnosis. (C) 2018 Elsevier Ltd. All rights reserved

    A genome-wide investigation of the worldwide invader Sargassum muticum shows high success albeit (almost) no genetic diversity

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    Twenty years of genetic studies of marine invaders have shown that successful invaders are often characterized by native and introduced populations displaying similar levels of genetic diversity. This pattern is presumably due to high propagule pressure and repeated introductions. The opposite pattern is reported in this study of the brown seaweed, Sargassum muticum, an emblematic species for circumglobal invasions. Albeit demonstrating polymorphism in the native range, microsatellites failed to detect any genetic variation over 1,269 individuals sampled from 46 locations over the Pacific-Atlantic introduction range. Single-nucleotide polymorphisms (SNPs) obtained from ddRAD sequencing revealed some genetic variation, but confirmed severe founder events in both the Pacific and Atlantic introduction ranges. Our study thus exemplifies the need for extreme caution in interpreting neutral genetic diversity as a proxy for invasive potential. Our results confirm a previously hypothesized transoceanic secondary introduction from NE Pacific to Europe. However, the SNP panel unexpectedly revealed two additional distinct genetic origins of introductions. Also, conversely to scenarios based on historical records, southern rather than northern NE Pacific populations could have seeded most of the European populations. Finally, the most recently introduced populations showed the lowest selfing rates, suggesting higher levels of recombination might be beneficial at the early stage of the introduction process (i.e., facilitating evolutionary novelties), whereas uniparental reproduction might be favored later in sustainably established populations (i.e., sustaining local adaptation).Agence Nationale de la Recherche - ANR-10-BTBR-04; European Regional Development Fund; Fundacao para a Ciencia e a Tecnologia - SFRH/BPD/107878/2015, UID/Multi/04326/2016, UID/Multi/04326/2019; Brittany Region;info:eu-repo/semantics/publishedVersio

    High-bandwidth uni-traveling carrier waveguide photodetector on an InP-membrane-on-silicon platform

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    A uni-traveling carrier photodetector (UTC-PD), heterogeneously integrated on silicon, is demonstrated. It is fabricated in an InP-based photonic membrane bonded on a silicon wafer, using a novel double-sided processing scheme. A very high 3 dB bandwidth of beyond 67 GHz is obtained, together with a responsivity of 0.7 A/W at 1.55 μm wavelength. In addition, open eye diagrams at 54 Gb/s are observed. These results promise high speed applications using a novel full-functionality photonic platform on silicon

    A Musical instrument in MEMS

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    In this work we describe a MEMS instrument that resonates at audible frequencies, and with which music can be made. The sounds are generated by mechanical resonators and capacitive displacement sensors. Damping by air scales unfavourably for generating audible frequencies with small devices. Therefore a vacuum of 1.5 mbar is used to increase the quality factor and consequently the duration of the sounds to around 0.25 s. The instrument will be demonstrated during the MME 2010 conference opening, in a musical composition especially made for the occasion

    The Effect of Corporate Support Programs on Employees’ Innovative Behavior: A Cross-Cultural Study

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    This article establishes a theoretical model that sheds light on whether corporate support programs can foster employees’ innovative behavior across nations and which national cultural dimensions moderate this relationship. To validate the arguments empirically, this research consists of two sequential, independent studies. The first study uses secondary data from the 2011 Global Entrepreneurship Monitor special report. Analysis of responses from 11,560 full-time employees in 13 countries shows that the relationship between support and innovative behavior is more positive when the nation's levels of power distance and masculinity are low and individualism is strong. A second experimental study is conducted in Germany and China using employees’ individual behavior as the dependent variable and corporate support programs differentiated into three types of corporate support (providing time, providing budget, and providing advice) as the independent variable. Findings indicate that all three types of corporate support programs positively impact employees’ innovative behavior in the sample from Germany, at least indirectly via feasibility and desirability judgments as mediators, but no significant relationships in the sample from China. This study contributes to the research stream on employees’ innovative behavior and corporate support programs by adding national cultural properties as environmental factors. In addition, this study investigates the mediating effect of feasibility and desirability judgments between three types of corporate support programs and innovative behavior. This study also contributes to innovation research in general and to research on employees’ innovative behavior in particular by building and validating a multilevel model empirically

    PMD5 VALUATION OF NEW DRUG APPLICATIONS OF PHARMACEUTICAL COMPANIES USING COMPOUND OPTION MODELS

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    Eutrophication problems, causes and potential solutions, and exchange of reusable model building components for the integrated simulation of coastal eutrophication. ISECA Final Report D3.2

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    This report summarizes the stages of coastal and offshore eutrophication, followed by a description of the European indicators and institutional framework for marine eutrophication assessment. A summary is given of a number of biogeochemical models available to describe the process of eutrophication in the North Sea, and the model for atmospheric inputs which was developed in the ISECA project (see the Action 3 Report – Atmospheric Modelling for more details on this work). Furthermore, the report compares different solutions aimed at reducing the nitrogen inputs from the Scheldt basin, using the nitrogen apportionment model which was developed in the EU-FP6 project SPICOSA (www.spicosa.eu). The report is concluded with a discussion on the principles of component-based modelling and model libraries, using examples for the Scheldt model, and a general discussion on some challenges of modelling marine eutrophication
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