5,917 research outputs found

    Nonlinear optical response of a gold surface in the visible range: A study by two-color sum-frequency generation spectroscopy. III. Simulations of the experimental SFG intensities

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    International audienceWe model the amplitude line shape and absolute phase of the infrared-visible sum-frequency signals produced by a thiolated polycrystalline gold surface as a function of the visible wavelength. We follow two hypotheses: in the interband scenario, the resonant features are attributed to interband transitions, whereas in the effective surface state scenario, they stem mostly from the excitation of surface transitions. We find that both scenarios lead to a satisfactory account of the experimental data and that only free electrons may spill out of the gold bulk, as expected. For the interband scenario, the balance between free and bound electron contributions to sum-frequency generation has to be adjusted to fit the data. The surface transitions are shown to take their origin inside gold and we investigate the surface states involved in such transitions, with a comparison to the silver surfaces. We finally provide a work program dedicated to discriminate between the two scenarios

    Application of Neural Networks for Energy Reconstruction

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    The possibility to use Neural Networks for reconstruction of the energy deposited in the calorimetry system of the CMS detector is investigated. It is shown that using feed - forward neural network, good linearity, Gaussian energy distribution and good energy resolution can be achieved. Significant improvement of the energy resolution and linearity is reached in comparison with other weighting methods for energy reconstruction.Comment: 18 pages, 13 figures, LATEX, submitted to: Nuclear Instruments & Methods

    Nonlinear optical response of a gold surface in the visible range: A study by two-color sum-frequency generation spectroscopy. I. Experimental determination

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    International audienceWe experimentally determine the effective nonlinear second-order susceptibility of gold over the visible spectral range. To reach that goal, we probe by vibrational two-color sum-frequency generation spectroscopy the methyl stretching region of a dodecanethiol self-assembled monolayer adsorbed on a gold film. The sum-frequency generation spectra show a remarkable shape reversal when the visible probe wavelength is tuned from 435 to 705 nm. After correcting from Fresnel effects, the methyl stretching vibrations serve as an internal reference, allowing to extract the dispersion of the absolute phase and relative amplitude of the effective nonlinear optical response of gold in the visible range. Published by AIP Publishing. https://doi

    Quality Enhancement of Highly Degraded Music Using Deep Learning-Based Prediction Models for Lost Frequencies

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    Audio quality degradation can have many causes. For musical applications, this fragmentation may lead to highly unpleasant experiences. Restoration algorithms may be employed to reconstruct missing parts of the audio in a similar way as for image reconstruction-in an approach called audio inpainting. Current state-of-The art methods for audio inpainting cover limited scenarios, with well-defined gap windows and little variety of musical genres. In this work, we propose a Deep-Learning-based (DL-based) method for audio inpainting accompanied by a dataset with random fragmentation conditions that approximate real impairment situations. The dataset was collected using tracks from different music genres to provide a good signal variability. Our best model improved the quality of all musical genres, obtaining an average of 12.9 dB of PSNR, although it worked better for musical genres in which acoustic instruments are predominant

    Idiopathic hypertrophic pachymeningitis presenting with occipital neuralgia

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    Background: Although occipital neuralgia is usually caused by degenerative arthropathy, nearly 20 other aetiologies may lead to this condition.Methods: We present the first case report of hypertrophic pachymeningitis revealed by isolated occipital neuralgia.Results and conclusions: Idiopathic hypertrophic pachymeningitis is a plausible cause of occipital neuralgia and may present without cranial-nerve palsy. There is no consensus on the treatment for idiopathic hypertrophic pachymeningitis, but the usual approach is to start corticotherapy and then to add immunosuppressants. When occipital neuralgia is not clinically isolated or when a first-line treatment fails, another disease diagnosis should be considered. However, the cost effectiveness of extended investigations needs to be considered.Keywords: neuralgia/pathology, meningitis, neck pain/aetiology, revie

    A Cluster-Matching-Based Method for Video Face Recognition

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    Face recognition systems are present in many modern solutions and thousands of applications in our daily lives. However, current solutions are not easily scalable, especially when it comes to the addition of new targeted people. We propose a cluster-matching-based approach for face recognition in video. In our approach, we use unsupervised learning to cluster the faces present in both the dataset and targeted videos selected for face recognition. Moreover, we design a cluster matching heuristic to associate clusters in both sets that is also capable of identifying when a face belongs to a non-registered person. Our method has achieved a recall of 99.435% and a precision of 99.131% in the task of video face recognition. Besides performing face recognition, it can also be used to determine the video segments where each person is present.Comment: 13 page

    Data filtering in the readout of the CMS Electromagnetic Calorimeter

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    For an efficient data taking, the Electromagnetic Calorimeter (ECAL) data of the CMS experiment must be limited to 10\% of the full event size (1MB). Other requirements limit the average data size to 2kB per data acquisition link. These conditions imply a reduction factor of close to twenty on the data collected. The data filtering in the readout of the ECAL detector is discussed. Test beam data are used to study the digital filtering applied in the readout channels and a full detector simulation allows to estimate the energy thresholds to achieve the desired data suppression factor

    Poly(I:C) induces intense expression of c-IAP2 and cooperates with an IAP inhibitor in induction of apoptosis in cancer cells

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    <p>Abstract</p> <p>Background</p> <p>There is increasing evidence that the toll-like receptor 3 (TLR3) is an interesting target for anti-cancer therapy. Unfortunately, most laboratory investigations about the impact of TLR3 stimulation on human malignant cells have been performed with very high concentrations - 5 to 100 Îźg/ml - of the prototype TLR3 ligand, poly(I:C). In a previous study focused on a specific type of human carcinoma - nasopharyngeal carcinoma - we have shown that concentrations of poly(I:C) as low as 100 ng/ml are sufficient to induce apoptosis of malignant cells when combined to a pharmacological antagonist of the IAP family based on Smac mimicry.</p> <p>Methods</p> <p>This observation prompted us to investigate the contribution of the IAP family in cell response to poly(I:C) in a variety of human malignant cell types.</p> <p>Results</p> <p>We report a rapid, intense and selective increase in c-IAP2 protein expression observed under stimulation by poly(I:C)(500 ng/ml) in all types of human malignant cells. In most cell types, this change in protein expression is underlain by an increase in c-IAP2 transcripts and dependent on the TLR3/TRIF pathway. When poly(I:C) is combined to the IAP inhibitor RMT 5265, a cooperative effect in apoptosis induction and/or inhibition of clonogenic growth is obtained in a large fraction of carcinoma and melanoma cell lines.</p> <p>Conclusions</p> <p>Currently, IAP inhibitors like RMT 5265 and poly(I:C) are the subject of separate therapeutic trials. In light of our observations, combined use of both types of compounds should be considered for treatment of human malignancies including carcinomas and melanomas.</p

    Search for the standard model Higgs boson in the H to ZZ to 2l 2nu channel in pp collisions at sqrt(s) = 7 TeV

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    A search for the standard model Higgs boson in the H to ZZ to 2l 2nu decay channel, where l = e or mu, in pp collisions at a center-of-mass energy of 7 TeV is presented. The data were collected at the LHC, with the CMS detector, and correspond to an integrated luminosity of 4.6 inverse femtobarns. No significant excess is observed above the background expectation, and upper limits are set on the Higgs boson production cross section. The presence of the standard model Higgs boson with a mass in the 270-440 GeV range is excluded at 95% confidence level.Comment: Submitted to JHE
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