23 research outputs found

    Study of ion emission from a germanium crystal surface under impact of fast Pb ions in channeling conditions

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    International audienceA thin germanium crystal has been irradiated at GANIL by Pb beams of 29 MeV/A (charge state Qin = 56 and 72) and of 5.6 MeV/A (Qin = 28). The induced ion emission from the sample entrance surface was studied, impact per impact, as a function of Qin, velocity vin and energy loss DE in the crystal. The Pb ions transmitted through the crystal were analyzed in charge (Qout) and energy using the SPEG spectrometer. The emitted ionized species were detected and analyzed in mass by a Time of Flight multianode detector (LAG). Channeling was used to select peculiar DE in Ge and hence peculiar Pb ion trajectories close to the emitting surface. The experiment was performed in standard vacuum. No Ge emission was found. The dominating emitted species are H+ and hydrocarbon ions originating from the contamination layer on top of the crystal. The mean value of the number of detected species per incoming Pb ion (multiplicity) varies as (Qin/vin)^p, with p values in agreement with previous results. We have clearly observed an influence of the energy deposition DE in Ge on the emission from the top contamination layer. When selecting increasing values of DE, we observed a rather slow increase of . On the contrary, the probabilities of high multiplicity values, that are essentially connected to fragmentation after emission, strongly increase with DE

    Surveillance study of apparent life-threatening events (ALTE) in the Netherlands

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    SIDS and ALTE are different entities that somehow show some similarities. Both constitute heterogeneous conditions. The Netherlands is a low-incidence country for SIDS. To study whether the same would hold for ALTE, we studied the incidence, etiology, and current treatment of ALTE in The Netherlands. Using the Dutch Pediatric Surveillance Unit, pediatricians working in second- and third-level hospitals in the Netherlands were asked to report any case of ALTE presented in their hospital from January 2002 to January 2003. A questionnaire was subsequently sent to collect personal data, data on pregnancy and birth, condition preceding the incident, the incident itself, condition after the incident, investigations performed, monitoring or treatment initiated during admission, any diagnosis made at discharge, and treatment or parental support offered after discharge. A total of 115 cases of ALTE were reported, of which 110 questionnaires were filled in and returned (response rate 97%). Based on the national birth rate of 200,000, the incidence of ALTE amounted 0.58/1,000 live born infants. No deaths occurred. Clinical diagnoses could be assessed in 58.2%. Most frequent diagnoses were (percentages of the total of 110 cases) gastro-esophageal reflux and respiratory tract infection (37.3% and 8.2%, respectively); main symptoms were change of color and muscle tone, choking, and gagging. The differences in diagnoses are heterogeneous. In 34%, parents shook their infants, which is alarmingly high. Pre- and postmature infants were overrepresented in this survey (29.5% and 8.2%, respectively). Ten percent had recurrent ALTE. In total, 15.5% of the infants were discharged with a home monitor. In conclusion, ALTE has a low incidence in second- and third-level hospitals in the Netherlands. Parents should be systematically informed about the possible devastating effects of shaking an infant. Careful history taking and targeted additional investigations are of utmost importance

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    Background: About 10 to 20% of children in West European countries have atopic dermatitis (AD), often as part of the atopic syndrome. The full atopic syndrome also consists of allergic asthma, allergic rhinitis and food allergy. Treatment approaches for atopic dermatitis and asthma include intermittent anti-inflammatory therapy with corticosteroids, health education and self-management training. However, symptoms persist in a subgroup of patients. Several observational studies have shown significant improvement in clinical symptoms in children and adults with atopic dermatitis or asthma after treatment at high altitude, but evidence on the efficacy when compared to treatment at sea level is still lacking.Methods/Design: This study is a pragmatic randomized controlled trial for children with moderate to severe AD within the atopic syndrome. Patients are eligible for enrolment in

    Ionisation en couche interne et effet biologique des rayonnements

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    Les effets biologiques d’une ionisation K ont Ă©tĂ© largement Ă©tudiĂ©s dans l’espoir de mieux comprendre les mĂ©canismes d’inactivation cellulaire et de rĂ©paration de l’ADN et pour dĂ©velopper d’éventuelles applications thĂ©rapeutiques. Les expĂ©riences faites avec des radionuclĂ©ides incorporĂ©s (125I) ou des Ă©lĂ©ments incorporĂ©s (Br, I, P) excitĂ©s sĂ©lectivement en couche K Ă  l’aide d’un rayonnement synchrotron ont toutes indiquĂ© un accroissement d’efficacitĂ© biologique K + Auger. L’intĂ©rĂȘt de l’ionisation K a resurgi rĂ©cemment lorsque certains travaux ont suggĂ©rĂ© que l’ionisation K des atomes de C, N, O de l’ADN pouvait ĂȘtre l’évĂ©nement physique primaire responsable de l’effet lĂ©tal des ions. Les expĂ©riences de photoabsorption au seuil K du carbone appuient cette hypothĂšse

    Factors associated with early introduction of complementary feeding and consumption of non-recommended foods among Dutch infants: the BeeBOFT study

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    Abstract Background Timing and types of complementary feeding in infancy affect nutritional status and health later in life. The present study aimed to investigate the factors associated with early introduction of complementary feeding (i.e., before age 4 months), and factors associated with infants consumption of non-recommended foods, including sweet beverages and snack foods. Methods This study used cross-sectional data from the BeeBOFT study (n = 2157). Data on complementary feeding practices and potential determinants were obtained by questionnaire at infant’s age of 6 months. Logistic regression models were used to investigate factors associated with early introduction of complementary feeding and infants’ consumption of non-recommended foods. Results 21.4% of infants had received complementary feeding before 4 months of age. At the age of 6 months, 20.2% of all infants were consuming sweet beverages daily and 16.5% were consuming snack foods daily. Younger maternal age, lower maternal educational level, absence or shorter duration of breastfeeding, parental conviction that “my child always wants to eat when he/she sees someone eating” and not attending day-care were independently associated with both early introduction of complementary feeding and the consumption of non-recommended foods. Higher maternal pre-pregnancy BMI and infant postnatal weight gain were associated only with early introduction of complementary feeding. Conclusions We identified several demographical, biological, behavioral, psychosocial, and social factors associated with inappropriate complementary feeding practices. These findings are relevant for designing intervention programs aimed at educating parents. Trial registration The trail is registered at Netherlands Trial Register, trail registration number: NTR1831. Retrospectively registered on May 29, 2009
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