Desarrollo, seguimiento y evaluación de la formación especializada en el modelo troncal.

La implantación de la troncalidad en la formación sanitaria especializada en España es el cambio más profundo y complejo que se introduce en la regulación del sistema de formación especializada desde el año 1978. Este hecho hace imprescindible la puesta en marcha de un conjunto de elementos estructurales, organizativos y de acción dirigidos específicamente a garantizar que el proceso se implante siguiendo las premisas y calendarios previstos en las disposiciones legales que le dan soporte y de acuerdo con conceptos y evidencias científicamente fundados y que traduzcan también la experiencia acumulada en España y otros países en relación con estos temas

Tratamiento asistido por artroscopia de las fracturas de radio distal

ResumenLa artroscopia proporciona una valoración directa de la superficie articular y permite detectar lesiones asociadas en las fracturas de la extremidad distal del radio. Su incorporación al tratamiento de estas fracturas ha supuesto un mejor control de la reducción de los trazos articulares, pero se trata de una técnica compleja que aún no está generalizada entre la mayoría de los cirujanos ortopédicos y/o de la mano y la muñeca.Se realiza una revisión y actualización de las ventajas, las indicaciones, las claves técnicas, los resultados y los datos científicos de su utilidad para el tratamiento de las fracturas del radio distal.AbstractArthroscopy provides a direct evaluation of the joint surface and enables associated injuries to be detected in fractures of the distal end of the radius. Although its incorporation into the treatment of these fractures has led to a better control in the reduction of joint traces, it is a complicated technique that is still not in general use by the majority of orthopaedic and/or hand and wrist surgeons.A review is presented here, as well as an update of the advantages, indications, the key techniques, results, and scientific data of its use in the treatment of distal radius fractures

Assessment of Tremor Severity in Patients with Essential Tremor Using Smartwatches

[Abstract] This paper presents a classification model for the automatic quantification of tremor severity in patients with essential tremor (ET). The system is based on the signals measured by two commercial smartwatches that the patients wear on their wrist and ankle. The smartwatches register acceleration and angular velocity in these body segments. A set of nine tremor features were used to train the classification algorithm. The proposed algorithm is based on a C4.5 decision tree classifier. It is able to assess rest and kinetic (postural or action) tremor. The method was evaluated using data collected from thirty-four patients with ET. The algorithm classifies the severity of tremor in five levels 0-4 corresponding to those in the Fahn-Tolosa-Marin tremor rating scale with a 94% accuracy. The method can be implemented in a networked platform for the remote monitoring and assessment of movement disorders such as ET or Parkinson’s disease.Ministerio de Economía, Industria u Competitividad; RTC-2015-3967-1Ministerio de Economía, Industria u Competitividad; DPI2015-68664-C4-1-RMinisterio de Economía, Industria u Competitividad; RTC-2015-4327-

Actions for the Restoration of the Biodiversity of Forest Ecosystems in Cuba

The Earth is threatened daily by the degradation of its ecosystems due to fragmentation. One of the main consequences is biodiversity loss. Despite the economic progress and conservation actions carried out in many countries, the planet is losing genuine tropical forest due to diverse reasons. This chapter presents the results obtained during the restoration of three tropical forests in Cuba: 1) the mesophyll semi-deciduous forest in the western sector of the Biosphere Reserve 'Sierra del Rosario' (BRSR); 2) the riverside forest of the Cuyaguateje River in western Cuba; and 3) the exploited native rainforests of the sector Quibiján-Naranjal of the River Toa in eastern Cuba

Association of Human Leukocyte Antigens Class II Variants with Susceptibility to Hidradenitis Suppurativa in a Caucasian Spanish Population

Hidradenitis suppurativa (HS) is a chronic inflammatory cutaneous disease of the hair follicle typically presenting recurrent, painful, and inflamed lesions on the inverse areas of the body. Although its pathogenesis remains unknown, the immune system appears to play a potential role. To date, two previous studies have not found any association between the Human Leukocyte Antigen system (HLA) and HS. In this study we analyzed the HLA-A, -B, -C; and DRB1, -DQA1, and ?DQB1 allele distribution in 106 HS patients and 262 healthy controls from a Caucasian population in Cantabria (northern Spain). HLA-A*29 and B*50 were significantly more common in HS patients and A*30 and B*37 in controls, but these associations disappeared after statistical correction. DRB1*07, DQA1*02, and DQB1*02 were significantly more common in controls (p 0.026, p 0.0012, and p 0.0005, respectively) and the HLA allele DQB1*03:01 was significantly more common in HS patients (p 0.00007) after the Bonferroni correction. The DRB1*07~DQA1*02~DQB1*02 haplotype was significantly more common in controls (p < 0.0005). This is the first study showing an association between HLA-class II and HS. Our results suggest that HLA-II alleles (DRB1*07, DQA1*02, DQB1*02, and DQB1*03:01) and the DRB1*07~DQA1*02~DQB1*02 haplotype could influence resistance or susceptibility to HS

Interaction with touchscreen smartphones in patientswith essential tremor and healthy individuals.

tremorAbstractIntroduction: Smartphone use in biomedical research is becoming more prevalent in differ-ent clinical settings. We performed a pilot study to obtain information on smartphone use bypatients with essential tremor (ET) and healthy controls, with a view to determining whetherperformance of touchscreen tasks is different between these groups and describing touchscreeninteraction factors.Method: A total of 31 patients with ET and 40 sex- and age-matched healthy controls com-pleted a descriptive questionnaire about the use of smartphones. Participants subsequentlyinteracted with an under-development Android application, and performed 4 tests evaluatingtypical touchscreen interaction gestures; each test was performed 5 times.Result: The type of smartphone use and touchscreen interaction were not significantly differ-ent between patients and controls. Age and frequency of smartphone use are key factors intouchscreen interaction.Conclusion: Our results support the use of smartphone touchscreens for research into ET,although further studies are required.pre-print1030 K

Development of a thermosensitive hydrogel based on Polaxamer 407 and gellan gum with inclusion complexes (Sulfobutylated-β-cyclodextrin-Farnesol) as a local drug delivery system

This work proposes the development of a thermosensitive local drug release system based on Polaxamer 407, also known as Pluronic® F-127 (PF-127), Gellan Gum (GG) and the inclusion complex Sulfobutylated-β-cyclodextrin (CD) with Farnesol (FOH). Rheological properties of the hydrogels and their degradation were studied. According to the rheological results, a solution of 20% w/v of PF-127 forms a strong gel with a gelling temperature of about 25 °C (storage modulus of 15,000 Pa). The addition of the GG increased the storage modulus (optimal concentration of 0.5 % w/v) twofold without modifying the gelling temperature. Moreover, including 0.5% w/v of GG also increased 6 times the degradation time of the hydrogel. Regarding the inclusion complex, the addition of free CD decreased the viscosity and the gel strength since polymer chains were included in CD cavity without affecting the gelling temperature. Contrarily, the inclusion complex CD-FOH did not significantly modify any property of the formulation because the FOH was hosted in the CD. Furthermore, a mathematical model was developed to adjust the degradation time. This model highlights that the addition of the GG decreases the number of released chains from the polymeric network (which coincides with an increase in the storage modulus) and that the free CD reduces the degradation rate, protecting the polymeric chains. Finally, FOH release was quantified with a specific device, that was designed and printed for this type of system, observing a sustainable drug release (similar to FOH aqueous solubility, 8 μM) dependent on polymer degradation