INTERVENCIÓN DE LA TRABAJADORA SOCIAL Y SU RELACIÓN CON EL NIVEL DE SATISFACCIÓN DE LOS USUARIOS DE CONSULTA EXTERNA DEL CENTRO DE SALUD EDIFICADORES MISTI DEL DISTRITO DE MIRAFLORES - AREQUIPA 2014

El presente estudio pretende conocer y determinar el nivel de satisfacción de los usuarios atendidos en Consulta Externa con elpropósito de precisar y definir los objetivos y actividades a realizar por la Trabajadora Social en este campo de intervención. Se analizaron las variables,satisfacción del usuario e intervención de la Trabajadora Social; así como los indicadores, considerando para el estudio una muestra de 130 usuarios atendidos por Consulta Externa en el Centro de Salud Edificadores Misti del Distrito de Miraflores. Los resultados obtenidos en el presente estudio, permiten conocer la poca satisfacción de los usuarios atendidos por consulta externa, determinando las expectativas del usuario en cuanto a la mejora del trato que brinda el personal de salud y el cumplimiento de los procedimientos (protocolo de atención al usuario) y de esta manera plantear proyectos de mejora continua para el establecimiento de salud desde la intervención de la Trabajadora Social, como es el diseño de propuestas de intervención, considerando dos proyectos: PROYECTO N° 1: Promoviendo una atención con calidad y calidez PROYECTO N° 2: Gestionando la calidad de los servicios de salu

Association Between Preexisting Versus Newly Identified Atrial Fibrillation and Outcomes of Patients With Acute Pulmonary Embolism

Background Atrial fibrillation (AF) may exist before or occur early in the course of pulmonary embolism (PE). We determined the PE outcomes based on the presence and timing of AF. Methods and Results Using the data from a multicenter PE registry, we identified 3 groups: (1) those with preexisting AF, (2) patients with new AF within 2 days from acute PE (incident AF), and (3) patients without AF. We assessed the 90-day and 1-year risk of mortality and stroke in patients with AF, compared with those without AF (reference group). Among 16 497 patients with PE, 792 had preexisting AF. These patients had increased odds of 90-day all-cause (odds ratio [OR], 2.81; 95% CI, 2.33-3.38) and PE-related mortality (OR, 2.38; 95% CI, 1.37-4.14) and increased 1-year hazard for ischemic stroke (hazard ratio, 5.48; 95% CI, 3.10-9.69) compared with those without AF. After multivariable adjustment, preexisting AF was associated with significantly increased odds of all-cause mortality (OR, 1.91; 95% CI, 1.57-2.32) but not PE-related mortality (OR, 1.50; 95% CI, 0.85-2.66). Among 16 497 patients with PE, 445 developed new incident AF within 2 days of acute PE. Incident AF was associated with increased odds of 90-day all-cause (OR, 2.28; 95% CI, 1.75-2.97) and PE-related (OR, 3.64; 95% CI, 2.01-6.59) mortality but not stroke. Findings were similar in multivariable analyses. Conclusions In patients with acute symptomatic PE, both preexisting AF and incident AF predict adverse clinical outcomes. The type of adverse outcomes may differ depending on the timing of AF onset.info:eu-repo/semantics/publishedVersio

MAREJADAS RURALES Y LUCHAS POR LA VIDA, VOL. II: CONFLICTOS SOCIOTERRITORIALES Y POR RECURSOS NATURALES

Volumen 2. Conflictos socioterritoriales y por recursos naturales, coordinado por: Rosalía López Paniagua, Dante Ariel Ayala Ortiz y Armando Contreras Hernández, constituido por 19 trabajos, divididos en tres secciones. La primera titulada Tierra: tenencia y cultivos transgénicos, contiene 6 trabajos, que abordan el persistente conflicto por la tenencia de la tierra y la producción de soya y maíz transgénico y la asociada acumulación del capital por despojo que caracteriza la agricultura transgénica en México, pero también formas de resistencia como la denuncia de contaminación transgénica en la Sierra Juárez de Oaxaca y las instituciones, actores y gestión en la Reserva de la Biósfera El Triunfo en la Sierra Madre de Chiapas. La segunda sección: Territorio: Explotación y envenenamiento, está compuesta por 5 trabajos que hacen referencia a los conflictos socioambientales derivados de la minería en manos de empresas nacionales y extranjeras omisas y gobiernos cómplices de las consecuencias depredadoras que generan en territorios campesinos e indígenas, debido a su asociación con el narcotráfico y por la contaminación del agua y la tierra que provocan, además de las consecuencias perversas en la salud humana y el entorno natural en diversas regiones del país. En la tercera y última sección, Agua: contaminación y escases, los 8 trabajos que la integran, analizan los conflictos socioterritoriales y luchas por la vida, en diversos estados del país. Se trata de investigaciones que estudian movimientos y conflictos sociales actuales en el campo mexicano, como son las luchas por la defensa del territorio y la defensa de la naturaleza, trabajos que abordan especialmente las disputas por el agua, y los problemas asociados del acceso, la escasez y la contaminación, no solo internos sino con empresas y con el Estado mismo que con la aprobación y aplicación de leyes y reglamentos, el despojo a los campesinos de su territorio en el que han trabajado y vivido por generaciones.INSTITUTO DE CIENCIAS AGROPECUARIAS Y RURALES (ICAR), UNIVERSIDAD DE GUADALAJARA, EL COLEGIO DE MICHOACÁN A.C., FACULTAD DE ESTUDIOS SUPERIORES ACATLÁN-UNAM, ECOSUR, CUCOSTA SUR GRANA, ASOCIACIÓN MEXICANA DE ESTUDIOS RURALES A.C

Multidifferential study of identified charged hadron distributions in ZZ-tagged jets in proton-proton collisions at s=\sqrt{s}=13 TeV

Jet fragmentation functions are measured for the first time in proton-proton collisions for charged pions, kaons, and protons within jets recoiling against a $Z$ boson. The charged-hadron distributions are studied longitudinally and transversely to the jet direction for jets with transverse momentum 20 $< p_{\textrm{T}} < 100$ GeV and in the pseudorapidity range $2.5 < \eta < 4$. The data sample was collected with the LHCb experiment at a center-of-mass energy of 13 TeV, corresponding to an integrated luminosity of 1.64 fb$^{-1}$. Triple differential distributions as a function of the hadron longitudinal momentum fraction, hadron transverse momentum, and jet transverse momentum are also measured for the first time. This helps constrain transverse-momentum-dependent fragmentation functions. Differences in the shapes and magnitudes of the measured distributions for the different hadron species provide insights into the hadronization process for jets predominantly initiated by light quarks.Comment: All figures and tables, along with machine-readable versions and any supplementary material and additional information, are available at https://cern.ch/lhcbproject/Publications/p/LHCb-PAPER-2022-013.html (LHCb public pages

Identification of a Cluster of HIV-1 Controllers Infected with Low Replicating Viruses

<div><p>Long term non-progressor patients (LTNPs) are characterized by the natural control of HIV-1 infection. This control is related to host genetic, immunological and virological factors. In this work, phylogenetic analysis of the proviral nucleotide sequences in <i>env</i> gene from a Spanish HIV-1 LTNPs cohort identified a cluster of 6 HIV-1 controllers infected with closely-related viruses. The patients of the cluster showed common clinical and epidemiological features: drug user practices, infection in the same city (Madrid, Spain) and at the same time (late 70’s-early 80’s). All cluster patients displayed distinct host alleles associated with HIV control. Analysis of the virus envelope nucleotide sequences showed ancestral characteristic, lack of evolution and presence of rare amino-acids. Biological characterization of recombinant viruses with the envelope proteins from the cluster viruses showed very low replicative capacity in TZMbl and U87-CD4/CCR5 cells. The lack of clinical progression in the viral cluster patients with distinct combinations of protective host genotypes, but infected by low replicating viruses, indicate the important role of the virus in the non-progressor phenotype in these patients.</p></div

Correlation between sampling time and the genetic distance with reference and viral cluster strains.

<p>MRCA-to-tip distances were extracted from MrBayes phylogenetic tree using TreeStat v.1.2. •, values obtained for the nucleotide sequences collected at the beginning of HIV-1 epidemic (years 1981–1995) were plotted against sampling time and a linear regression analysis was performed. Red Δ, values obtained from the cluster nucleotide sequences. The red dashed line and the arrow permit the extrapolation of the year from cluster nucleotide sequences.</p

C2-V5 nucleotide sequences from patient LTNP_1.

<p>LTNP_1 samples were obtained from PBMC DNA (2005 sample), cell-free supernatant of PBMC co-culture from a 2004 sample and plasma RNA corresponding to a 2010 sample. Shaded boxes indicated amino acid mutations characteristics of the cluster viruses in this C2-V5 region. V3, V4 and V5 regions are indicated by boxes.</p

Biological characterization of the recombinant viruses.

<p>A) Infectivity of <i>env</i> recombinant viruses in TZM-bl cells. Cells were infected with 15 units of HIV-1 p24 antigen (75 pg) of virus-supernatants. Luciferase activity was measured 48 hours post-infection and the results were normalized to the value obtained with the WT virus (89ES061). Results represented the median and SE of two independent assays with thee replicates. B) Replication kinetics of <i>env</i> recombinant viruses in U87-CD4/CCR5 cells. Cells were infected with 100 units of HIV- 1 p24 antigen (500 pg) of virus supernatants. Cultures were followed during 14 days, and HIV-1 production was quantified by the RT-activity in the supernatant with in-house Syber green I based real-time PCR enhanced RT assay (SGPERT). Cluster’s recombinant viruses (red) were compared with recombinant viruses from chronic progressor patients (green), with a recombinant virus obtained from laboratory strain SF-162 (black), and with the laboratory infectious clone 89ES061 (black) where the nucleotide sequences were cloned.</p

Identification of amino acid positions associated with the cluster viruses.

<p>Identification of amino acid positions associated with the cluster viruses.</p