324 research outputs found

    Seismic retrofitting of RC frames with RC infilling

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    The effectiveness of seismic retrofitting of multi-storey multi-bay RC-frame buildings, by converting selected bays into new walls through infilling with RC, was studied experimentally at the ELSA facility at JRC, Ispra, and the results are reported here. The full-scale model tested with the pseudo-dynamic method consisted of two parallel frames, linked through 0.15m slabs, having three bays each (8.5m long), with the central bay (2.5m) infilled with RC wall, and being four storeys tall (12m). The frames were designed and detailed for gravity loads only and are typical of similar frames built in Cyprus in the 1970's. Different connection details and reinforcement percentages for the two infilled frames were used in order to study the effects of these parameters. The results of the pseudo-dynamic and cyclic testing performed are presented and conclusions are drawn

    Evaluation of seismic demand for substandard reinforced concrete structures

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    Background: Reinforced Concrete (RC) buildings with no seismic design exhibit degrading behaviour under severe seismic loading due to non-ductile brittle failure modes. The seismic performance of such substandard structures can be predicted using existing capacity demand diagram methods through the idealization of the non-linear capacity curve of the degrading system, and its comparison with a reduced earthquake demand spectrum. Objective: Modern non-linear static methods for derivation of capacity curves incorporate idealization assumptions that are too simplistic and do not apply for sub-standard buildings. The conventional idealisation procedures cannot maintain the true strength degradation behaviour of such structures in the post-peak part, and thus may lead to significant errors in seismic performance prediction especially in the cases of brittle failure modes dominating the response. Method: In order to increase the accuracy of the prediction, an alternative idealisation procedure using equivalent elastic perfectly plastic systems is proposed herein that can be used in conjunction with any capacity demand diagram method. Results: Moreover, the performance of this improved equivalent linearization procedure in predicting the response of an RC frame is assessed herein. Conclusion: This improved idealization procedure has been proven to reduce the error in the seismic performance prediction as compared to seismic shaking table test results [1] and will be further investigated probabilistically herein

    The role of thrombospondins in wound healing, ischemia, and the foreign body reaction

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    Thrombospondin (TSP) 1 and TSP2 have been implicated in the regulation of several processes during tissue repair. Due to their matricellular nature, these proteins are thought to modulate cell-matrix interactions through a variety of mechanisms specific to the spatio-temporal context of their expression. Most notably, TSP1 and TSP2 appear to play distinct, non-overlapping roles in the healing of skin wounds. In contrast, both proteins have been implicated as regulators of ischemia-induced angiogenesis. Moreover, TSP2 has been shown to be a critical regulator of angiogenesis in the foreign body response (FBR). In this review, we discuss the role of TSPs in tissue repair and examine the mechanistic data regarding the ability of the thrombospondins to modulate cell-matrix interactions in this context

    Lymphoepithelial Cyst of the Pancreas.

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    The final, published version of this article is available at doi: 10.1159/000445373Lymphoepithelial cyst (LEC) of the pancreas is an extremely rare, benign pancreatic cystic lesion that is difficult to differentiate preoperatively from other cystic pancreatic lesions. LEC may have malignant potential. Here, we describe a case of LEC of the pancreas - initially suspected to be a mucinous cyst neoplasm - in an elderly man presenting with abdominal pain, who went on to have a distal pancreatectomy and splenectomy. We also review the relevant literature and discuss implications for the diagnosis and management of this rare lesion

    GEOMATICS AND CIVIL ENGINEERING INNOVATIVE RESEARCH ON HERITAGE: INTRODUCING THE “ENGINEER” PROJECT

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    This paper aims to introduce the concept and objectives of a recently supported European project entitled “Geomatics and Civil Engineering Innovative Research on Heritage”, in short ENGINEER. The ENGINEER project visions to enhance and extend inter-departmental multidisciplinary research activities of the Department of Civil Engineering & Geomatics of the Cyprus University of Technology through coordination and support actions as well as through targeted research activities with the support of European leading institutions. Project tasks aim to fill research multidisciplinary gaps, push, and extend knowledge into new and innovative fields dealing with the monitoring, digitization, visualization, and preservation of ancient monuments and cultural heritage sites, assisting their protection, promotion, and safeguarding
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