Design, Characterization and Evaluation of Metallic Nano Biocomposites of Neomycin

Neomycin is formulated into nanoparticles in order to increase the therapeutic efficacy, decrease the dose of drug and to decrease the topical dose related toxic effects. The present study was aimed at the preparation of zinc nanoparticles (ZN), chitosan nanoparticles (CN), zinc neomycin nanoparticles (ZNN) and zinc chitosan neomycin nanoparticles (ZCNN) in order to compare their antibacterial activity. Nanoparticles were prepared by subjecting the nano suspension containing the specified ingredients to stirring at 40oC for 4-5 h. The prepared nanoparticles were evaluated for particle size and surface morphology by Transmission Electron Microscopy (TEM), mean particle size and particle size distribution by DLS, percentage yield, loading efficiency, in vitro drug release by diffusion technique and agar cup plate method. TEM microphotographs and zeta sizer analysis revealed that the prepared nanoparticles were in the nanometric range, the particle size and particle size range of ZCNN was less compared to ZNN indicated more surface area of ZCNN. Among all the nanoparticles prepared, percentage yield, loading efficiency, in vitro drug release and zone of inhibition was found to be more for ZCNN. Thus, the results suggested that ZCNN act as promising drug delivery systems with better in vitro characteristics compared to other nanoparticles with increased therapeutic activity of neomycin

Surgical Management of a Rare Case of Scrotal Lymphangioma in Ongole Bull

An unusual case of scrotal lymphangioma in a ongole bull is described. A 5 years old ongole bull was presented with a eight month history of swelling at the neck of scrotum. On palpation the swelling was hard in consistency. Fine needle aspiration revealed no sign of malignancy. On surgical exploration of scrotal swelling, a hard mass was observed adhering to the outerlayers of spermatic cord. The mass was excised without disturbing the testes and the associated structures. Based on cytological and histopathological examination the mass was diagnosed as lymphangioma. The surgical treatment was successful and the animal had uneventful recovery without any complications

Adenocarcinoma of Nictitans Gland in a Cow- A Case Report

A 7 year old cow was presented to the College of Veterinary Science clinic (Sri Venkateswara Veterinary University, Tirupati, India), with the history of growth appeared on the third eyelid of the left eye. The mass was surgically excised, and subjected to histopathological examination. Histopathological examination revealed lobules of irregular size and shape with proliferated cells, which were arranged as small tubules with or without necrotic centers. Cells were anaphylactic, large and irregular with hyperchromatic nuclei. Acini showed many layers of cells with papillary projections. Mitotic figures were also present

Gastrotomy for Retrieval of Thoracic Oesophageal Foriegn Body Using Long Forceps Technique in Three Dogs

Three dogs age between 3- 6 years old was presented to the Department of Veterinary Surgery and Radiology with the history of anorexia, attempt for vomiting, regurgitation, dysphagia, gagging, mild salivation after taking a piece of bone. Clinical examination revealed heart rate and respiratory were within physiological limits. Lateral plain radiograph of thorax revealed radio opaque foreign body was lodged between heart and diaphragm. Surgical invention was planned to retrieve thoracic oesophageal foreign body through gastrotomy incision. This clinical paper reports the successful surgical management of thoracic oesophageal foreign body through gastrotomy incision using long forceps without complication

Open data from the third observing run of LIGO, Virgo, KAGRA, and GEO

The global network of gravitational-wave observatories now includes five detectors, namely LIGO Hanford, LIGO Livingston, Virgo, KAGRA, and GEO 600. These detectors collected data during their third observing run, O3, composed of three phases: O3a starting in 2019 April and lasting six months, O3b starting in 2019 November and lasting five months, and O3GK starting in 2020 April and lasting two weeks. In this paper we describe these data and various other science products that can be freely accessed through the Gravitational Wave Open Science Center at https://gwosc.org. The main data set, consisting of the gravitational-wave strain time series that contains the astrophysical signals, is released together with supporting data useful for their analysis and documentation, tutorials, as well as analysis software packages

Congenital Absence of Tail with Atresia Ani and Hypospadias in a Kid- A Case Report

One day old kid was presented to the Department of Veterinary Surgery and Radiology, College of Veterinary Science, Sri Venkateswara Veterinary University, Tirupati with the history of not passing feces since birth. Based on the clinical, physical and lateral radiographic examinations, the condition was diagnosed as hypospadias along with penile aplasia and atresia ani without tail. Animal made an uneventful recovery after the seventh post operative day

Synthesis and electromagnetic properties of U-type hexaferrites Ba 4B 2Fe 36O 60 (B: Co, Ni, Cu)

10.1016/j.jmmm.2012.08.019Journal of Magnetism and Magnetic Materials32563-68JMMM