Depression in College Students: The Influence of Coping Strategies, Optimism, and Daily Hassles

College students (n=250) were given a survey packet containing reliable instruments for the measure of depression, coping strategies, optimism, and daily hassles. Depression in college students was hypothesized to be positively correlated with avoidance and frequent daily hassles; whereas problem-solving, social support coping, and optimism were hypothesized to be negatively correlated with a depressed effect. Hierarchical multiple regression produced empirical support that frequent daily hassles and avoidant coping strategies exacerbates depression in a college population. Data analysis assessed a significant relationship between optimism and decreased depression. The coping strategies of problem-solving and social support did not enter into a significant relationship with depression or buffer the development of depressive symptoms. This study examines and expands upon prior research of depression in college students by reviewing related psychological literature, contributing empirical research, and making suggestions for further research

The Effects of Rumination and Distraction Tasks on Psychophysiological Responses and Self-Reported Mood in Dysphoric and Nondysphoric Individuals

According to the response style theory of depression (Nolen-Hoeksema, 1987), the way in which individuals respond to depressed mood affects the severity and duration of that mood. Prior laboratory studies of response style have not included psychophysiological measures or investigated the relationship between ruminative response style and the conceptually-related constructs of worry and neuroticism. Dysphoric (n = 84) and nondysphoric participants (n = 86) were randomly assigned to either a rumination task (i.e., self-focused attention) or a distraction task (i.e., other-focused attention). In addition to the pre-task and post-task mood ratings used in prior response style studies, the present study included measures of worry, neuroticism and psychophysiological response. Greater psychophysiological response and self-reported depressed mood and worry were anticipated in the dysphoric ruminators as compared to the dysphoric distractors and the nondysphoric ruminators and distractors. Results supported prior findings that distraction and rumination differentially impact depressed mood in dysphoric individuals; dysphoric ruminators reported significantly higher levels of post-task depressed mood than did dysphoric distractors. Of the psychophysiological responses measured, a significant difference in post-rumination systolic blood pressure was found between nondysphoric men and women. Additionally, post-rumination worry ratings were significantly higher than the post-distraction worry ratings, regardless of initial dysphoria status. The implications of these results for future response style research are discussed

Health behaviour counselling in primary care : general practitioner : reported rate and confidence

Aims: The study aimed to identify variables associated with General Practitioners’ (GPs’) self-reported rate of health behaviour change counselling and confidence in counselling abilities. Methodology: This study was a repeat of a similar study carried out at the Mayo Clinic in 2007. The same tool and methodology were used with the permission of the authors. Variables measured by the questionnaire included: participants’ characteristics, physical activity, smoking status, healthy eating behaviour, self-reported rate of counselling behaviour, extent of training in counselling, perceived importance of counselling, confidence for health behaviour change counselling. A comparative analysis of the results was made.peer-reviewe

Feasibility Testing of the Alert for AFib Intervention.

Improving early detection and treatment of atrial fibrillation (AF) is critical because untreated AF is a major contributor to stroke and heart failure. We sought to generate knowledge about the feasibility of conducting a randomized controlled trial to test the effect of the Alert for AFib intervention on knowledge, attitudes, and beliefs about treatment-seeking for signs and symptoms of AF. Adults ≥65 years old (96% White) at risk for developing AF were randomized to receive the Alert for AFib intervention ( n = 40) or an attention control session ( n = 40). Feasibility goals for recruitment, participant retention, adherence, perceived satisfaction and burden, and intervention fidelity were met. From baseline to study completion, knowledge ( p = .005) and attitudes ( p < .001) about treatment-seeking improved more in the intervention group compared with the control group. Results support testing the effectiveness of the Alert for AFib intervention in a large trial

Hubungan Kepercayaan Diri Dengan Komunikasi Interpersonal Pada Mahasiswa Angkatan 2013 Program Studi Ilmu Keperawatan Universitas Sam Ratulagi Manado

: Background In the interpersonal communication, confidence is needed because the recognition and appreciation of communication we will have if we have the confidence..Purpose to know The Relationship Between Interpersonal Communication with Confidence for Student class 2013 at Nursing Department, Sam Ratulangi University Manado. Design is observational analytic with approach cross sectional. Population entire student class of 2013 at Nursing Department, Sam Ratulangi University, with number 109 students and Sample use purposive sampling, with number 57 students. The data collected were processed using SPSS computer assistance (Statistical Programme For Social Science) version 20 using the chi-square test at 95% significance level (á 0.05).Result obtained value of P =0,152 more than á = 0,05 (p 0,05).Conclusion there is not relationship between interpersonal communication with confidence for student class 2013 at Nursing Department, Sam Ratulangi University Manado. Suggestion consideration for the department as teaching materials for courses Psychiatric Nursing, and the student is expected to improve the knowledge about confidence and interpersonal communication

Guidelines for reporting of statistics for clinical research in urology

Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/148242/1/bju14640.pdfhttps://deepblue.lib.umich.edu/bitstream/2027.42/148242/2/bju14640_am.pd

Offspring of Mothers Fed a High Fat Diet Display Hepatic Cell Cycle Inhibition and Associated Changes in Gene Expression and DNA Methylation

The association between an adverse early life environment and increased susceptibility to later-life metabolic disorders such as obesity, type 2 diabetes and cardiovascular disease is described by the developmental origins of health and disease hypothesis. Employing a rat model of maternal high fat (MHF) nutrition, we recently reported that offspring born to MHF mothers are small at birth and develop a postnatal phenotype that closely resembles that of the human metabolic syndrome. Livers of offspring born to MHF mothers also display a fatty phenotype reflecting hepatic steatosis and characteristics of non-alcoholic fatty liver disease. In the present study we hypothesised that a MHF diet leads to altered regulation of liver development in offspring; a derangement that may be detectable during early postnatal life. Livers were collected at postnatal days 2 (P2) and 27 (P27) from male offspring of control and MHF mothers (n = 8 per group). Cell cycle dynamics, measured by flow cytometry, revealed significant G0/G1 arrest in the livers of P2 offspring born to MHF mothers, associated with an increased expression of the hepatic cell cycle inhibitor Cdkn1a. In P2 livers, Cdkn1a was hypomethylated at specific CpG dinucleotides and first exon in offspring of MHF mothers and was shown to correlate with a demonstrable increase in mRNA expression levels. These modifications at P2 preceded observable reductions in liver weight and liver∶brain weight ratio at P27, but there were no persistent changes in cell cycle dynamics or DNA methylation in MHF offspring at this time. Since Cdkn1a up-regulation has been associated with hepatocyte growth in pathologic states, our data may be suggestive of early hepatic dysfunction in neonates born to high fat fed mothers. It is likely that these offspring are predisposed to long-term hepatic dysfunction

The Effects of the Monoamine Stabilizer (-)-OSU6162 on Binge-Like Eating and Cue-Controlled Food-Seeking Behavior in Rats.

Binge-eating disorder (BED) is characterized by recurring episodes of excessive consumption of palatable food and an increased sensitivity to food cues. Patients with BED display an addiction-like symptomatology and the dopamine system might be a potential treatment target. The clinically safe monoamine stabilizer (-)-OSU6162 (OSU6162) restores dopaminergic dysfunction in long-term alcohol-drinking rats and shows promise as a novel treatment for alcohol use disorder. Here, the effects of OSU6162 on consummatory (binge-like eating) and appetitive (cue-controlled seeking) behavior motivated by chocolate-flavored sucrose pellets were evaluated in non-food-restricted male Lister Hooded rats. OSU6162 significantly reduced binge-like intake of chocolate-flavored sucrose pellets without affecting prior chow intake. Furthermore, OSU6162 significantly reduced the cue-controlled seeking of chocolate-flavored sucrose pellets under a second-order schedule of reinforcement before, but not after, the delivery and ingestion of reward, indicating a selective effect on incentive motivational processes. In contrast, the dopamine D2/D3 receptor antagonist raclopride reduced the seeking of chocolate-flavored sucrose pellets both pre- and post reward ingestion and also reduced responding under simpler schedules of seeking behavior. The D1/5 receptor antagonist SCH23390 had no effect on instrumental behavior under any reinforcement schedule tested. Finally, local administration of OSU6162 into the nucleus accumbens core, but not dorsolateral striatum, selectively reduced cue-controlled sucrose seeking. In conclusion, the present results show that OSU6162 reduces binge-like eating behavior and attenuates the impact of cues on seeking of palatable food. This indicates that OSU6162 might serve as a novel BED medication.These studies were financially supported by a grant from the Swedish Society of Medicine (SLS-253061) to PS and JA, and a Medical Research Council Programme Grant (no. G1002231) to BJE. The Behavioural and Clinical Neuroscience Institute is cofunded by the Medical Research Council and the Welcome Trust. JA was supported by the Swedish Pharmaceutical Society and the Swedish Research Council (350-2012-230). A travel grant from the Swedish Society for Medical Research enabled KF to participate in this collaboration. PS was supported by the Swedish Research Council (2015-03525)

Building a transdisciplinary expert consensus on the cognitive drivers of performance under pressure: An international multi-panel Delphi study

IntroductionThe ability to perform optimally under pressure is critical across many occupations, including the military, first responders, and competitive sport. Despite recognition that such performance depends on a range of cognitive factors, how common these factors are across performance domains remains unclear. The current study sought to integrate existing knowledge in the performance field in the form of a transdisciplinary expert consensus on the cognitive mechanisms that underlie performance under pressure.MethodsInternational experts were recruited from four performance domains [(i) Defense; (ii) Competitive Sport; (iii) Civilian High-stakes; and (iv) Performance Neuroscience]. Experts rated constructs from the Research Domain Criteria (RDoC) framework (and several expert-suggested constructs) across successive rounds, until all constructs reached consensus for inclusion or were eliminated. Finally, included constructs were ranked for their relative importance.ResultsSixty-eight experts completed the first Delphi round, with 94% of experts retained by the end of the Delphi process. The following 10 constructs reached consensus across all four panels (in order of overall ranking): (1) Attention; (2) Cognitive Control—Performance Monitoring; (3) Arousal and Regulatory Systems—Arousal; (4) Cognitive Control—Goal Selection, Updating, Representation, and Maintenance; (5) Cognitive Control—Response Selection and Inhibition/Suppression; (6) Working memory—Flexible Updating; (7) Working memory—Active Maintenance; (8) Perception and Understanding of Self—Self-knowledge; (9) Working memory—Interference Control, and (10) Expert-suggested—Shifting.DiscussionOur results identify a set of transdisciplinary neuroscience-informed constructs, validated through expert consensus. This expert consensus is critical to standardizing cognitive assessment and informing mechanism-targeted interventions in the broader field of human performance optimization