284 research outputs found
Near-threshold boson pair production in the model of smeared-mass unstable particles
Near-threshold production of boson pairs is considered within the framework
of the model of unstable particles with smeared mass. We describe the principal
aspects of the model and consider the strategy of calculations including the
radiative corrections. The results of calculations are in good agreement with
LEP II data and Monte-Carlo simulations. Suggested approach significantly
simplifies calculations with respect to the standard perturbative one.Comment: 15 pages, 6 figures, minor corrections, references adde
Impact of an interatrial shunt device on survival and heart failure hospitalization in patients with preserved ejection fraction
Aims:
Impaired left ventricular diastolic function leading to elevated left atrial pressures, particularly during exertion, is a key driver of symptoms and outcomes in heart failure with preserved ejection fraction (HFpEF). Insertion of an interatrial shunt device (IASD) to reduce left atrial pressure in HFpEF has been shown to be associated with short‐term haemodynamic and symptomatic benefit. We aimed to investigate the potential effects of IASD placement on HFpEF survival and heart failure hospitalization (HFH).
Methods and results:
Heart failure with preserved ejection fraction patients participating in the Reduce Elevated Left Atrial Pressure in Patients with Heart Failure study (Corvia Medical) of an IASD were followed for a median duration of 739 days. The theoretical impact of IASD implantation on HFpEF mortality was investigated by comparing the observed survival of the study cohort with the survival predicted from baseline data using the Meta‐analysis Global Group in Chronic Heart Failure heart failure risk survival score. Baseline and post‐IASD implant parameters associated with HFH were also investigated. Based upon the individual baseline demographic and cardiovascular profile of the study cohort, the Meta‐analysis Global Group in Chronic Heart Failure score‐predicted mortality was 10.2/100 pt years. The observed mortality rate of the IASD‐treated cohort was 3.4/100 pt years, representing a 33% lower rate (P = 0.02). By Kaplan–Meier analysis, the observed survival in IASD patients was greater than predicted (P = 0.014). Baseline parameters were not predictive of future HFH events; however, poorer exercise tolerance and a higher workload‐corrected exercise pulmonary capillary wedge pressure at the 6 months post‐IASD study were associated with HFH.
Conclusions:
The current study suggests IASD implantation may be associated with a reduction in mortality in HFpEF. Large‐scale ongoing randomized studies are required to confirm the potential benefit of this therapy
Scientific Opportunities with an X-ray Free-Electron Laser Oscillator
An X-ray free-electron laser oscillator (XFELO) is a new type of hard X-ray
source that would produce fully coherent pulses with meV bandwidth and stable
intensity. The XFELO complements existing sources based on self-amplified
spontaneous emission (SASE) from high-gain X-ray free-electron lasers (XFEL)
that produce ultra-short pulses with broad-band chaotic spectra. This report is
based on discussions of scientific opportunities enabled by an XFELO during a
workshop held at SLAC on June 29 - July 1, 2016Comment: 21 pages, 12 figure
Active wetting of epithelial tissues
Development, regeneration and cancer involve drastic transitions in tissue
morphology. In analogy with the behavior of inert fluids, some of these
transitions have been interpreted as wetting transitions. The validity and
scope of this analogy are unclear, however, because the active cellular forces
that drive tissue wetting have been neither measured nor theoretically
accounted for. Here we show that the transition between 2D epithelial
monolayers and 3D spheroidal aggregates can be understood as an active wetting
transition whose physics differs fundamentally from that of passive wetting
phenomena. By combining an active polar fluid model with measurements of
physical forces as a function of tissue size, contractility, cell-cell and
cell-substrate adhesion, and substrate stiffness, we show that the wetting
transition results from the competition between traction forces and contractile
intercellular stresses. This competition defines a new intrinsic lengthscale
that gives rise to a critical size for the wetting transition in tissues, a
striking feature that has no counterpart in classical wetting. Finally, we show
that active shape fluctuations are dynamically amplified during tissue
dewetting. Overall, we conclude that tissue spreading constitutes a prominent
example of active wetting --- a novel physical scenario that may explain
morphological transitions during tissue morphogenesis and tumor progression
Synchrotron x ray scattering study of charge density wave order in HgBa2CuO4 delta
We present a detailed synchrotron x-ray scattering study of the
charge-density-wave (CDW) order in simple tetragonal HgBaCuO
(Hg1201). Resonant soft x-ray scattering measurements reveal that short-range
order appears at a temperature that is distinctly lower than the pseudogap
temperature and in excellent agreement with a prior transient reflectivity
result. Despite considerable structural differences between Hg1201 and
YBaCuO, the CDW correlations exhibit similar doping
dependencies, and we demonstrate a universal relationship between the CDW wave
vector and the size of the reconstructed Fermi pocket observed in quantum
oscillation experiments. The CDW correlations in Hg1201 vanish already below
optimal doping, once the correlation length is comparable to the CDW modulation
period, and they appear to be limited by the disorder potential from unit cells
hosting two interstitial oxygen atoms. A complementary hard x-ray diffraction
measurement, performed on an underdoped Hg1201 sample in magnetic fields along
the crystallographic axis of up to 16 T, provides information about the
form factor of the CDW order. As expected from the single-CuO-layer
structure of Hg1201, the CDW correlations vanish at half-integer values of
and appear to be peaked at integer . We conclude that the atomic
displacements associated with the short-range CDW order are mainly planar,
within the CuO layers
The Decays to -wave Charmonium by Improved Bethe-Salpeter Approach
We re-calculate the exclusive semileptonic and nonleptonic decays of
meson to a -wave charmonium in terms of the improved Bethe-Salpeter (B-S)
approach, which is developed recently. Here the widths for the exclusive
semileptonic and nonleptonic decays, the form factors, and the charged lepton
spectrums for the semileptonic decays are precisely calculated. To test the
concerned approach by comparing with experimental measurements when the
experimental data are available, and to have comparisons with the other
approaches the results obtained by the approach and those by some approaches
else as well as the original B-S approach, which appeared in literature, are
comparatively presented and discussed.Comment: 33 pages, 5 figures, 3 table
Top A_FB at the Tevatron vs. charge asymmetry at the LHC in chiral U(1) flavor models with flavored Higgs doublets
We consider the top forward-backward (FB) asymmetry at the Tevatron and top
charge asymmetry at the LHC within chiral U(1)^\prime models with
flavor-dependent U(1)^\prime charges and flavored Higgs fields, which were
introduced in the ref. [65]. The models could enhance not only the top
forward-backward asymmetry at Tevatron, but also the top charge asymmetry at
LHC, without too large same-sign top pair production rates. We identify
parameter spaces for the U(1)^\prime gauge boson and (pseudo)scalar Higgs
bosons where all the experimental data could be accommodated, including the
case with about 125 GeV Higgs boson, as suggested recently by ATLAS and CMS.Comment: 11 pages, 6 figures, figures and discussion adde
Last Call for RHIC Predictions
This paper contains the individual contributions of all speakers of the
session on 'Last Call for RHIC Predictions' at Quark Matter 99, and a summary
by the convenor.Comment: 56 pages, psfig, epsf, epsfig, graphicx style files required,
Proceedings of the XIV Int. Conf. on Nucleus-Nucleus Collisions, Quark Matter
99, Torino, Italy, May 10 - 15, 1999. Typographical mistakes corrected and
figure numbers change
TESLA Technical Design Report Part III: Physics at an e+e- Linear Collider
The TESLA Technical Design Report Part III: Physics at an e+e- Linear
ColliderComment: 192 pages, 131 figures. Some figures have reduced quality. Full
quality figures can be obtained from http://tesla.desy.de/tdr. Editors -
R.-D. Heuer, D.J. Miller, F. Richard, P.M. Zerwa
- …