982 research outputs found

    Global warming will affect the maximum potential abundance of boreal plant species

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    Forecasting the impact of future global warming on biodiversity requires understanding how temperature limits the distribution of species. Here we rely on Liebig's Law of Minimum to estimate the effect of temperature on the maximum potential abundance that a species can attain at a certain location. We develop 95%‐quantile regressions to model the influence of effective temperature sum on the maximum potential abundance of 25 common understory plant species of Finland, along 868 nationwide plots sampled in 1985. Fifteen of these species showed a significant response to temperature sum that was consistent in temperature‐only models and in all‐predictors models, which also included cumulative precipitation, soil texture, soil fertility, tree species and stand maturity as predictors. For species with significant and consistent responses to temperature, we forecasted potential shifts in abundance for the period 2041–2070 under the IPCC A1B emission scenario using temperature‐only models. We predict major potential changes in abundance and average northward distribution shifts of 6–8 km yr−1. Our results emphasize inter‐specific differences in the impact of global warming on the understory layer of boreal forests. Species in all functional groups from dwarf shrubs, herbs and grasses to bryophytes and lichens showed significant responses to temperature, while temperature did not limit the abundance of 10 species. We discuss the interest of modelling the ‘maximum potential abundance’ to deal with the uncertainty in the predictions of realized abundances associated to the effect of environmental factors not accounted for and to dispersal limitations of species, among others. We believe this concept has a promising and unexplored potential to forecast the impact of specific drivers of global change under future scenarios.202

    Bayesian lasso binary quantile regression

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    In this paper, a Bayesian hierarchical model for variable selection and estimation in the context of binary quantile regression is proposed. Existing approaches to variable selection in a binary classification context are sensitive to outliers, heteroskedasticity or other anomalies of the latent response. The method proposed in this study overcomes these problems in an attractive and straightforward way. A Laplace likelihood and Laplace priors for the regression parameters are proposed and estimated with Bayesian Markov Chain Monte Carlo. The resulting model is equivalent to the frequentist lasso procedure. A conceptional result is that by doing so, the binary regression model is moved from a Gaussian to a full Laplacian framework without sacrificing much computational efficiency. In addition, an efficient Gibbs sampler to estimate the model parameters is proposed that is superior to the Metropolis algorithm that is used in previous studies on Bayesian binary quantile regression. Both the simulation studies and the real data analysis indicate that the proposed method performs well in comparison to the other methods. Moreover, as the base model is binary quantile regression, a much more detailed insight in the effects of the covariates is provided by the approach. An implementation of the lasso procedure for binary quantile regression models is available in the R-package bayesQR

    Changes in extreme sea-levels in the Baltic Sea

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    In a climate change context, changes in extreme sea-levels rather than changes in the mean are of particular interest from the coastal protection point of view. In this work, extreme sea-levels in the Baltic Sea are investigated based on daily tide gauge records for the period 1916–2005 using the annual block maxima approach. Extreme events are analysed based on the generalised extreme value distribution considering both stationary and time-varying models. The likelihood ratio test is applied to select between stationary and non-stationary models for the maxima and return values are estimated from the final model. As an independent and complementary approach, quantile regression is applied for comparison with the results from the extreme value approach. The rates of change in the uppermost quantiles are in general consistent and most pronounced for the northernmost stations

    Incidence and consequences of damage to insecticide-treated mosquito nets in Kenya

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    BACKGROUND: Efforts to improve the impact of long-lasting insecticidal nets (LLINs) should be informed by understanding of the causes of decay in effect. Holes in LLINs have been estimated to account for 7-11% of loss in effect on vectorial capacity for Plasmodium falciparum malaria in an analysis of repeated cross-sectional surveys of LLINs in Kenya. This does not account for the effect of holes as a cause of net attrition or non-use, which cannot be measured using only cross-sectional data. There is a need for estimates of how much these indirect effects of physical damage on use and attrition contribute to decay in effectiveness of LLINs. METHODS: Use, physical integrity, and survival were assessed in a cohort of 4514 LLINs followed for up to 4 years in Kenya. Flow diagrams were used to illustrate how the status of nets, in terms of categories of use, physical integrity, and attrition, changed between surveys carried out at 6-month intervals. A compartment model defined in terms of ordinary differential equations (ODEs) was used to estimate the transition rates between the categories. Effects of physical damage to LLINs on use and attrition were quantified by simulating counterfactuals in which there was no damage. RESULTS: Allowing for the direct effect of holes, the effect on use, and the effect on attrition, 18% of the impact on vectorial capacity was estimated to be lost because of damage. The estimated median lifetime of the LLINs was 2.9 years, but this was extended to 5.7 years in the counterfactual without physical damage. Nets that were in use were more likely to be in a damaged state than unused nets but use made little direct difference to LLIN lifetimes. Damage was reported as the reason for attrition for almost half of attrited nets, but the model estimated that almost all attrited nets had suffered some damage before attrition. CONCLUSIONS: Full quantification of the effects of damage will require measurement of the supply of new nets and of household stocks of unused nets, and also of their impacts on both net use and retention. The timing of mass distribution campaigns is less important than ensuring sufficient supply. In the Kenyan setting, nets acquired damage rapidly once use began and the damage led to rapid attrition. Increasing the robustness of nets could substantially increase their lifetime and impact but the impact of LLIN programmes on malaria transmission is ultimately limited by levels of use. Longitudinal analyses of net integrity data from different settings are needed to determine the importance of physical damage to nets as a driver of attrition and non-use, and the importance of frequent use as a cause of physical damage in different contexts

    A novel application of quantile regression for identification of biomarkers exemplified by equine cartilage microarray data

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    <p>Abstract</p> <p>Background</p> <p>Identification of biomarkers among thousands of genes arrayed for disease classification has been the subject of considerable research in recent years. These studies have focused on disease classification, comparing experimental groups of effected to normal patients. Related experiments can be done to identify tissue-restricted biomarkers, genes with a high level of expression in one tissue compared to other tissue types in the body.</p> <p>Results</p> <p>In this study, cartilage was compared with ten other body tissues using a two color array experimental design. Thirty-seven probe sets were identified as cartilage biomarkers. Of these, 13 (35%) have existing annotation associated with cartilage including several well-established cartilage biomarkers. These genes comprise a useful database from which novel targets for cartilage biology research can be selected. We determined cartilage specific Z-scores based on the observed M to classify genes with Z-scores ≄ 1.96 in all ten cartilage/tissue comparisons as cartilage-specific genes.</p> <p>Conclusion</p> <p>Quantile regression is a promising method for the analysis of two color array experiments that compare multiple samples in the absence of biological replicates, thereby limiting quantifiable error. We used a nonparametric approach to reveal the relationship between percentiles of M and A, where M is log<sub>2</sub>(R/G) and A is 0.5 log<sub>2</sub>(RG) with R representing the gene expression level in cartilage and G representing the gene expression level in one of the other 10 tissues. Then we performed linear quantile regression to identify genes with a cartilage-restricted pattern of expression.</p

    "My Children and I Will no Longer Suffer from Malaria": A Qualitative Study of the Acceptance and Rejection of Indoor Residual Spraying to Prevent Malaria in Tanzania.

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    The objective of this study was to identify attitudes and misconceptions related to acceptance or refusal of indoor residual spraying (IRS) in Tanzania for both the general population and among certain groups (e.g., farmers, fishermen, community leaders, and women). This study was a series of qualitative, semi-structured, in-depth interviews and focus group discussions conducted from October 2010 to March 2011 on Mainland Tanzania and Zanzibar. Three groups of participants were targeted: acceptors of IRS (those who have already had their homes sprayed), refusers (those whose communities have been sprayed, but refused to have their individual home sprayed), and those whose houses were about to be sprayed as part of IRS scale-up. Interviews were also conducted with farmers, fishermen, women, community leaders and members of non-government organizations responsible for community mobilization around IRS. Results showed refusers are a very small percentage of the population. They tend to be more knowledgeable people such as teachers, drivers, extension workers, and other civil servants who do not simply follow the orders of the local government or the sprayers, but are skeptical about the process until they see true results. Refusal took three forms: 1) refusing partially until thorough explanation is provided; 2) accepting spray to be done in a few rooms only; and 3) refusing outright. In most of the refusal interviews, refusers justified why their houses were not sprayed, often without admitting that they had refused. Reasons for refusal included initial ignorance about the reasons for IRS, uncertainty about its effectiveness, increased prevalence of other insects, potential physical side effects, odour, rumours about the chemical affecting fertility, embarrassment about moving poor quality possessions out of the house, and belief that the spray was politically motivated. To increase IRS acceptance, participants recommended more emphasis on providing thorough public education, ensuring the sprayers themselves are more knowledgeable about IRS, and asking that community leaders encourage participation by their constituents rather than threatening punishment for noncompliance. While there are several rumours and misconceptions concerning IRS in Tanzania, acceptance is very high and continues to increase as positive results become apparent

    Global distribution and bioclimatic characterization of alpine biomes

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    Although there is a general consensus on the distribution and ecological features of terrestrial biomes, the allocation of alpine ecosystems in the global biogeographic system is still unclear. Here, we delineate a global map of alpine areas above the treeline by modelling regional treeline elevation at 30 m resolution, using global forest cover data and quantile regression. We then used global datasets to 1) assess the climatic characteristics of alpine ecosystems using principal component analysis, 2) define bioclimatic groups by an optimized cluster analysis and 3) evaluate patterns of primary productivity based on the normalized difference vegetation index. As defined here, alpine biomes cover 3.56 Mkm(2) or 2.64% of land outside Antarctica. Despite temperature differences across latitude, these ecosystems converge below a sharp threshold of 5.9 degrees C and towards the colder end of the global climatic space. Below that temperature threshold, alpine ecosystems are influenced by a latitudinal gradient of mean annual temperature and they are climatically differentiated by seasonality and continentality. This gradient delineates a climatic envelope of global alpine biomes around temperate, boreal and tundra biomes as defined in Whittaker's scheme. Although alpine biomes are similarly dominated by poorly vegetated areas, world ecoregions show strong differences in the productivity of their alpine belt irrespectively of major climate zones. These results suggest that vegetation structure and function of alpine ecosystems are driven by regional and local contingencies in addition to macroclimatic factors
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