On the parameterization of eddy transfer, Part II: Tests with a channel model

In Part I of this paper (Killworth, 1997), a new eddy parameterization scheme was presented. Here, the scheme is tested by comparing its predictions with those of multi-year averages from an eddy-resolving channel model. Its accuracy is similar to that of a tuned version of previous schemes. However, a tuned version of the new parameterization can reproduce both the long-term average of the eddy-resolving solution as well as the initial slumping of a narrow front. Both tuned schemes reproduced the bolus transport well. The new parameterization reproduces the observed feature that the diffusivity is maximal at mid-depth and minimal at surface and floor

On the parameterization of eddy transfer Part I. Theory

This is the first of three linked papers which develop an eddy parameterization scheme for mean flows which are wide compared with a deformation radius. The scheme is partly based on the behavior of potential vorticity and thickness fluxes in linear instability, where the former are downgradient (apart from a turning matrix, not present in channel models) and the latter are not precisely downgradient, except on an f-plane. The scheme leads to a diffusivity which varies quite strongly with depth and is smallest at surface and floor. Intrinsic delta-function fluxes also occur at surface and floor, and these are worked out in detail. It is shown that all such parameterization schemes (whether linked to linear instability or not) must satisfy a necessary consistency condition, in the form of a vertical integral. A uniform diffusivity does not satisfy this requirement unless it is defined to vanish at surface and floor. Two methods to compute approximate diffusivities efficiently are given, and their results compare well with exact results from instability theory

Wave propagation and growth on a surface front in a two-layer geostrophic current

We study analytically and numerically small amplitude perturbations of a geostrophically balanced semi-infinite layer of light water having a surface front and lying above a heavier layer of finite vertical thickness which is at rest in the mean. In contrast with previous studies where the latter layer was infinitely deep we find that the equilibrium is always unstable regardless of the distribution of potential vorticity, and the maximum growth rates are generally much larger than in the one-layer case. The amplifying ageostrophic wave transfers kinetic energy from the basic shear flow as well as potential energy. Good quantitative agreement is found with the laboratory experiments of Griffiths and Linden (1982), and our model seems to be the simplest one for future investigations of cross frontal mixing processes by finite amplitude waves. The propagation speed of very low frequency and nondispersive frontal waves is also computed and is shown to decrease with increasing bottom layer depth

Energetics of linear geostrophic adjustment in stratified rotating fluids

The energy conversion ratio, γ, is shown to be bounded below by 0 and above by 1/2 in the two-dimensional linear geostrophic adjustment of a continuously stably stratified, incompressible, inviscid non-Boussinesq fluid. \u27\u27Two-dimensional\u27\u27 refers to problems in which the initial isopycnal displacement field is an arbitrary function of the vertical (parallel to the rotation axis) and a single horizontal coordinate. By using Fourier analysis techniques, the paper also identified classes of initial isopycnal displacement profiles for which the adjustment process leads to γ \u3e 1/3. Finally, an expression for γ is derived when the initial isopycnal displacement profile is three dimensional

Comparando dos métodos de estimación del tamaño de las redes personales

En este artículo comparamos dos métodos para la estimación del tamaño de las redes personales utilizando una muestra representativa de Estados Unidos a nivel nacional. Ambos métodos se basan en la habilidad de las personas encuestadas para estimar el número de personas que conocen en subpoblaciones específicas de EE.UU. (ej.: diabéticos, nativo-americanos) y gente en categorías específicas de relación (ej.: familia inmediata, compañeros de trabajo). Los resultados muestran una remarcable similitud entre el tamaño medio de la red obtenido por ambos métodos (aproximadamente 291). Se obtuvieron resultados similares con una muestra nacional distinta. La tentativa de corroboración de nuestras estimaciones mediante una reproducción exacta de la encuesta entre un segmento de población propenso a tener redes más amplias (el clero), dio como resultado un tamaño medio de la red superior. Una investigación extensiva sobre la existencia de efectos de respuesta mostró algunas preferencias por usar ciertos números a la hora de realizar estimaciones, pero nada que afectase de forma significativa a la estimación de tamaño de la red más allá del 6 por ciento. Nuestra conclusión es que ambos métodos utilizados para la estimación del tamaño de las redes personales proporcionan resultados válidos y fiables del tamaño de la red real, pero quedan algunas cuestiones pendientes sobre la exactitud.In this paper we compare two methods for estimating the size of personal networks using a nationally representative sample of the United States. Both methods rely on the ability of respondents to estimate the number of people they know in specific subpopulations of the U.S. (e.g., diabetics, Native Americans) and people in particular relation categories (e.g., immediate family, coworkers). The results demonstrate a remarkable similarity between the average network size generated by both methods (approximately 291). Similar results were obtained with a separate national sample. An attempt to corroborate our estimates by replicati among a population we suspect has large networks (clergy), yielded a larger average network size. Extensive investigation into the existence of response effects showed some preference for using certain numbers when making estimates, but nothing that would significantly affect the estimate of network size beyond about 6 percent. We conclude that both methods for estimating personal network size yield valid and reliable proxies for actual network size, but questions about accuracy remain

Activation of Insulin-Like Growth Factor II Receptor Induces Mitochondrial-Dependent Apoptosis through G alpha q and Downstream Calcineurin Signaling in Myocardial Cells

[[abstract]]In previous studies, we have found that IGF-II and IGF-II receptor (IGF-IIR) dose dependently correlated with the progression of pathological hypertrophy after complete abdominal aorta ligation, which may play a critical role in angiotensin II-induced cardiomyocyte apoptosis. However, the detail mechanisms of IGF-IIR in the regulation of cell apoptosis in response to IGF-II remain unclear. By using IGF-IR short hairpin RNA to inhibit IGF-IR expression and using Leu27 IGF-II analog to activate specifically the IGF-IIR, we investigated the role of IGF-II/IGF-IIR activation and its downstream signaling. Our results revealed that IGF-II synergistically increased the cell apoptosis induced by suppressing of IGF-IR in neonatal rat ventricular myocytes. After binding of Leu27IGF-II, IGF-IIR became associated with alpha-q polypeptide, acted like a protein-coupled receptor to activate calcineurin, led to the translocation of Bad into mitochondria and release of cytochrome c into cytoplasm, and contributed to mitochondrial-dependent apoptosis in neonatal rat ventricular myocytes. Furthermore, inhibition of IGF-IIR, alpha-q polypeptide, or calcineurin by RNA interference could block the Leu27IGF-II-induced cell apoptosis. Together, this study provides a new insight into the effects of the IGF-IIR and its downstream signaling in myocardial apoptosis. Suppression of IGF-IIR signaling pathways may be a good strategy for both the protection against myocardial cell apoptosis and the prevention of heart failure progression. (Endocrinology 150: 2723-2731, 2009

The Speed of Observed and Theoretical Long Extratropical Planetary Waves

Planetary or Rossby waves are the predominant way in which the ocean adjusts on long (year to decade) timescales. The motion of long planetary waves is westward, at speeds ≥1 cm s⁻¹ . Until recently, very few experimental investigations of such waves were possible because of scarce data. The advent of satellite altimetry has changed the situation considerably. Curiously, the speeds of planetary waves observed by TOPEX/Poseidon are mainly faster than those given by standard linear theory. This paper examines why this should be. It is argued that the major changes to the unperturbed wave speed will be caused by the presence of baroclinic east–west mean flows, which modify the potential vorticity gradient. Long linear perturbations to such flow satisfy a simple eigenvalue problem (related directly to standard quasigeostrophic theory). Solutions are mostly real, though a few are complex. In simple situations approximate solutions can be obtained analytically. Using archive data, the global problem is treated. Phase speeds similar to those observed are found in most areas, although in the Southern Hemisphere an underestimate of speed by the theory remains. Thus, the presence of baroclinic mean flow is sufficient to account for the majority of the observed speeds. It is shown that phase speed changes are produced mainly by (vertical) mode-2 east–west velocities, with mode-1 having little or no effect. Inclusion of the mean barotropic flow from a global eddy-admitting model makes only a small modification to the fit with observations; whether the fit is improved is equivocal

Circulation characteristics in three eddy-permitting models of the North Atlantic

A systematic intercomparison of three realistic eddy-permitting models of the North Atlantic circulation has been performed. The models use different concepts for the discretization of the vertical coordinate, namely geopotential levels, isopycnal layers, terrain-following (sigma) coordinates, respectively. Although these models were integrated under nearly identical conditions, the resulting large-scale model circulations show substantial differences. The results demonstrate that the large-scale thermohaline circulation is very sensitive to the model representation of certain localised processes, in particular to the amount and water mass properties of the overflow across the Greenland-Scotland region, to the amount of mixing within a few hundred kilometers south of the sills, and to several other processes at small or sub-grid scales. The different behaviour of the three models can to a large extent be explained as a consequence of the different model representation of these processes