Customer application protocol for data transfer between embedded processor and microcontroller systems

This paper develops a new customer application protocol (CAP) to improve the efficiency of transferring data between embedded processor and microcontroller systems. The established protocol is characterized by its fidelity and simplicity for using a small header to control and monitor the data flow between the two systems. This is achieved by constructing an embedded processor system with an Ethernet intellectual property (IP) core featured by lightweight IP (lwIP) to settle a connection with a microcontroller device. The embedded system is configured on spartan6E FPGAs slice. The system performance is tested by transferring audio samples and displaying them on chipscope media. The performance test of the designed embedded system with the developed customer application protocol showed fast, efficient and high precision data exchange between the processor and microcontroller systems

On the application of proper orthogonal decomposition (POD) for in-cylinder flow analysis

Proper orthogonal decomposition (POD) is a coherent structure identification technique based on either measured or computed data sets. Recently, POD has been adopted for the analysis of the in-cylinder flows inside internal combustion engines. In this study, stereoscopic particle image velocimetry (Stereo-PIV) measurements were carried out at the central vertical tumble plane inside an engine cylinder to acquire the velocity vector fields for the in-cylinder flow under different experimental conditions. Afterwards, the POD analysis were performed firstly on synthetic velocity vector fields with known characteristics in order to extract some fundamental properties of the POD technique. These data were used to reveal how the physical properties of coherent structures were captured and distributed among the POD modes, in addition to illustrate the difference between subtracting and non-subtracting the ensemble average prior to conducting POD on datasets. Moreover, two case studies for the in-cylinder flow at different valve lifts and different pressure differences across the air intake valves were presented and discussed as the effect of both valve lifts and pressure difference have not been investigated before using phase-invariant POD analysis. The results demonstrated that for repeatable flow pattern, only the first mode was sufficient to reconstruct the physical properties of the flow. Furthermore, POD analysis confirmed the negligible effect of pressure difference and subsequently the effect of engine speed on flow structures

Nonlinear dynamics of non-equilibrium holes in p-type modulation-doped GaInNAs/GaAs quantum wells

Nonlinear charge transport parallel to the layers of p-modulation-doped GaInNAs/GaAs quantum wells (QWs) is studied both theoretically and experimentally. Experimental results show that at low temperature, T = 13 K, the presence of an applied electric field of about 6 kV/cm leads to the heating of the high mobility holes in the GaInNAs QWs, and their real-space transfer (RST) into the low-mobility GaAs barriers. This results in a negative differential mobility and self-generated oscillatory instabilities in the RST regime. We developed an analytical model based upon the coupled nonlinear dynamics of the real-space hole transfer and of the interface potential barrier controlled by space-charge in the doped GaAs layer. Our simulation results predict dc bias-dependent self-generated current oscillations with frequencies in the high microwave range

Surgical Approaches to Congenital Anomalies of Esophagus

With prevalence of about 1 in 3000 live births, pediatric surgeons commonly deal with esophageal abnormalities, which may provide substantial clinical complications. Surprisingly, the embryologic processes underlying esophageal atresia (EA) with or without tracheoesophageal fistula (TEF), one of the hallmark disease entities of pediatric surgery, have only lately been largely uncovered. When it comes to the treatment of congenital esophageal abnormalities, notably esophageal atresia and tracheoesophageal fistula, surgical methods are essential. In order to address the anatomical abnormalities and restore normal function, surgical correction is often necessary in the care of congenital esophageal anomalies, including esophageal atresia and tracheoesophageal fistula. In this review we are going to cover surgical approaches to repair those malformations, long-term outcomes, and latest developments in esophageal surgical approaches

Expanding the Y Dwarf Census with Spitzer Follow-up of the Coldest CatWISE Solar Neighborhood Discoveries

We present Spitzer 3.6 and 4.5 μm follow-up of 170 candidate extremely cool brown dwarfs newly discovered via the combination of Wide-field Infrared Survey Explorer (WISE) and NEOWISE imaging at 3–5 μm. CatWISE, a joint analysis of archival WISE and NEOWISE data, has improved upon the motion measurements of AllWISE by leveraging a >10× time baseline enhancement, from 0.5 yr (AllWISE) to 6.5 yr (CatWISE). As a result, CatWISE motion selection has yielded a large sample of previously unrecognized brown dwarf candidates, many of which have archival detections exclusively in the WISE 4.6 μm (W2) channel, suggesting that they could be both exceptionally cold and nearby. Where these objects go undetected in WISE W1 (3.4 μm), Spitzer can provide critically informative detections at 3.6 μm. Of our motion-confirmed discoveries, 17 have a best-fit Spitzer [3.6]–[4.5] color most consistent with spectral type Y. It is likely that CWISEP J144606.62–231717.8 (μ ≈ 1.”3 yr⁻¹) is the reddest, and therefore potentially coldest, member of our sample with a very uncertain [3.6]–[4.5] color of 3.71 ± 0.44 mag. We also highlight our highest proper-motion discovery, WISEA J153429.75–104303.3, with μ ≈ 2.”7 yr⁻¹. Given that the prior list of confirmed and presumed Y dwarfs consists of just 27 objects, the Spitzer follow-up presented in this work has substantially expanded the sample of identified Y dwarfs. Our new discoveries thus represent significant progress toward understanding the bottom of the substellar mass function, investigating the diversity of the Y dwarf population, and selecting optimal brown dwarf targets for James Webb Space Telescope spectroscopy

Technical and economic feasibility of solar powered air conditioners in Brunei Darussalam

On daily basis, a huge amount of fossil fuel is being burnt which results in a substantial amount of greenhouse gasses being released into the atmosphere. Air conditioners are becoming more common and are a major strain on energy demands especially in tropical climate countries like Brunei Darussalam. The photovoltaic electricity is a clean and sustainable. In this paper, we present a techno-economic feasibility study for solar powered air conditioning system in Brunei Darussalam. Four alternatives are investigated, 1) the PV system supplies 50% of the loads, 2) the PV system supplies 75% of the loads, 3) the PV system supplies 100% of the loads, and finally 4) the PV system supplies 125% of the loads. Where in the last two case the excess electricity is sold to the grid. With 0.3$ feed-in tariff. The best alternative is the grid-connected PV system with 125% capacity factor which was chosen due to its short payback time period as well as high profit rate over the lifetime of the project

Modelling and simulation of 1.2 MWpTenaga suria brunei photovoltaic power plant

The energy demand in Brunei Darussalam will increase in near future. The renewable energy is one of the alternative energy sources that could satisfy the increasing energy demands. Brunei Darussalam depends heavily on fossil fuel to generate its electricity needs. Fossil fuels are depleted and the main source of pollution. Photovoltaic (PV) systems generate electricity directly from the sunlight without any emission of global warming gases, and the fuel is free. In order to optimize the performance of PV systems their operation should be well understood. In this paper, we present the modelling of a real 1.2 MWp photovoltaic system. The PV power plant is tied to the grid. The PV array, the DC/DC converter and the DC/AC inverter are modelled and implemented in Matlab/Simulink. The controller of the grid-connected inverter is modelled to achieve constant voltage, constant frequency and to be synchronized with the grid. The system is simulated under Brunei weather conditions and the results are acceptable. © 2019 Mattingley Publishing. All rights reserved

High catechin concentrations detected in Withania somnifera (ashwagandha) by high performance liquid chromatography analysis

<p>Abstract</p> <p>Background</p> <p><it>Withania somnifera </it>is an important medicinal plant traditionally used in the treatment of many diseases. The present study was carried out to characterize the phenolic acids, flavonoids and 1,1-diphenyl-2-picrylhydrazyl radical (DPPH) scavenging activities in methanolic extracts of <it>W. somnifera </it>fruits, roots and leaves (WSFEt, WSREt and WSLEt).</p> <p>Methods</p> <p>WSFEt, WSREt and WSLEt was prepared by using 80% aqueous methanol and total polyphenols, flavonoids as well as DPPH radical scavenging activities were determined by spectrophotometric methods and phenolic acid profiles were determined by HPLC methods.</p> <p>Results</p> <p>High concentrations of both phenolics and flavonoids were detected in all parts of the plant with the former ranging between 17.80 ± 5.80 and 32.58 ± 3.16 mg/g (dry weight) and the latter ranging between 15.49 ± 1.02 and 31.58 ± 5.07 mg/g. All of the three different plant parts showed strong DPPH radical scavenging activities (59.16 ± 1.20 to 91.84 ± 0.38%). Eight polyphenols (gallic, syringic, benzoic, p-coumaric and vanillic acids as well as catechin, kaempferol and naringenin) have been identified by HPLC in parts of the plant as well. Among all the polyphenols, catechin was detected in the highest concentration (13.01 ± 8.93 to 30.61 ± 11.41 mg/g).</p> <p>Conclusion</p> <p>The results indicating that <it>W. somnifera </it>is a plant with strong therapeutic properties thus further supporting its traditional claims. All major parts of <it>W. somnifera </it>such as the roots, fruits and leaves provide potential benefits for human health because of its high content of polyphenols and antioxidant activities with the leaves containing the highest amounts of polyphenols specially catechin with strong antioxidant properties.</p

Efficacy and Safety of AmBisome in Combination with Sodium Stibogluconate or Miltefosine and Miltefosine Monotherapy for African Visceral Leishmaniasis: Phase II Randomized Trial.

BACKGROUND: SSG&PM over 17 days is recommended as first line treatment for visceral leishmaniasis in eastern Africa, but is painful and requires hospitalization. Combination regimens including AmBisome and miltefosine are safe and effective in India, but there are no published data from trials of combination therapies including these drugs from Africa. METHODS: A phase II open-label, non-comparative randomized trial was conducted in Sudan and Kenya to evaluate the efficacy and safety of three treatment regimens: 10 mg/kg single dose AmBisome plus 10 days of SSG (20 mg/kg/day), 10 mg/kg single dose AmBisome plus 10 days of miltefosine (2.5mg/kg/day) and miltefosine alone (2.5 mg/kg/day for 28 days). The primary endpoint was initial parasitological cure at Day 28, and secondary endpoints included definitive cure at Day 210, and pharmacokinetic (miltefosine) and pharmacodynamic assessments. RESULTS: In sequential analyses with 49-51 patients per arm, initial cure was 85% (95% CI: 73-92) in all arms. At D210, definitive cure was 87% (95% CI: 77-97) for AmBisome + SSG, 77% (95% CI 64-90) for AmBisome + miltefosine and 72% (95% CI 60-85) for miltefosine alone, with lower efficacy in younger patients, who weigh less. Miltefosine pharmacokinetic data indicated under-exposure in children compared to adults. CONCLUSION: No major safety concerns were identified, but point estimates of definitive cure were less than 90% for each regimen so none will be evaluated in Phase III trials in their current form. Allometric dosing of miltefosine in children needs to be evaluated. TRIAL REGISTRATION: The study was registered with ClinicalTrials.gov, number NCT01067443