Teaching ethics:intersectionality, care failure and moral courage

Highlights• Provides a critical discussion of ethics teaching arguing that it must recognise begin to recognise frameworks from outside the Anglo-European tradition.• Drawing on examples of care failure, racism and sexism, argues that there is evidence that some nurses struggle to practice in accordance with ethical guidance.• Identifies intersectionality, the culture of practice and moral courage as fundamental to enabling nurses to practice in accordance with ethical guidance• Presents a case for an approach to applied approach ethics education, which recognises the complexity and diversity of practice

De-Centering “The” Survey: The Value of Multiple Introductory Surveys to Art History

This essay stems from our concern that art historians still conceive of “The” Survey in terms that privilege Western artistic traditions. In this article, we offer an alternative that we designate as the multi-survey model (MSM) or approach. “The survey” becomes “the surveys” that introduce students to Western arts and the art forms of often underrepresented regions. Twenty-one percent of the schools surveyed in our peer review employ similar models, and yet the MSM has yet to attract critical scholarly attention. This essay addresses a void in present scholarship and elaborates upon three main goals of the MSM, all of which help to de-center the survey from Western origins and to challenge the discourse that positions Western art as normative. First, the MSM creates opportunities for students to delve into the particularities of a specific region and its narratives of art, which often exist outside Western art historical discourse. Second, the MSM produces a productive dialogue between the Western survey and the regional surveys of Africa, the Americas, Asia, the Middle East, Pacific Cultures, and other regions. Last, students investigate agency of representation, and in particular how the arts of Asia and the Americas are presented in the Western world. The MSM deliberately concedes global coverage in favor of capitalizing upon the strengths of faculty members in small art history departments. The MSM ensures that students engage with a variety of cultural perspectives early in their art history careers and bolsters our efforts to create a more globally aware citizenry at the college level

Plastination Procedure @ PCOM: Current Practice and Future Uses

Introduction: Since its invention by German anatomist Gunther von Hagens, the process of forced-impregnation plastination of organic specimens has become the standard for the preservation of biological tissue specimens. This practice serves as the most practical method to preserve these specimens for study and is utilized at PCOM regularly for this purpose. During the steps of plastination, aqueous and lipid tissues are replaced by a curable polymer to produce plastinates that do not decompose, can be handled without gloves, and retain most characteristics of the original specimens. For decades, PCOM used this method to prepare a permanent teaching collection in support of medical education. In the last five years, the lab has been reactivated and prepares specimens for allied health professional education, enrichment of the Doctor of Osteopathy curriculum, and outreach at regional institutions (e.g., The Franklin Institute, The Nebinger School, etc.). Objectives: The purpose of this poster is to inform the PCOM community of current plastination practices and suggest future uses. Methods: To prepare specimens for plastination, they must be preserved in fixative. We currently dissect and stage all tissues after the fixative process. Dissections are prepared by work-study students at PCOM who have completed the relevant anatomy course (interested students please contact Dr. Claeson). After fixation, tissues are dehydrated in progressively more concentrated washes of cold-temperature acetone (-20ºC) until concentration is between 98-100%. After dehydration, they are placed into a silicone polymer bath and brought to room temperature. The room temperature bath technique is the primary deviation from von Hagen (1977). Once at room temperature in the bath, vacuum pressure is used to replace the acetone that fills each cell with silicone. A hardening agent is then administered to finish the process. Results & Conclusions: Current initiatives have included building a collection of heart specimens to support a cardiac workshop which pairs anatomy and physiology. Most recently, a brain anatomy collection is being built. Brain specimens include axial cross sections, whole and half brains, and pathological specimens. These specimens are currently used at many outreach events and will be incorporated into a featured anatomy series as part of the medical school curriculum. Future research initiatives may also begin via current practices

Restoration of Sp4 in Forebrain GABAergic Neurons Rescues Hypersensitivity to Ketamine in Sp4 Hypomorphic Mice.

BackgroundKetamine produces schizophrenia-like behavioral phenotypes in healthy people. Prolonged ketamine effects and exacerbation of symptoms after the administration of ketamine have been observed in patients with schizophrenia. More recently, ketamine has been used as a potent antidepressant to treat patients with major depression. The genes and neurons that regulate behavioral responses to ketamine, however, remain poorly understood. Sp4 is a transcription factor for which gene expression is restricted to neuronal cells in the brain. Our previous studies demonstrated that Sp4 hypomorphic mice display several behavioral phenotypes relevant to psychiatric disorders, consistent with human SP4 gene associations with schizophrenia, bipolar disorder, and major depression. Among those behavioral phenotypes, hypersensitivity to ketamine-induced hyperlocomotion has been observed in Sp4 hypomorphic mice.MethodsIn the present study, we used the Cre-LoxP system to restore Sp4 gene expression, specifically in either forebrain excitatory or GABAergic inhibitory neurons in Sp4 hypomorphic mice. Mouse behavioral phenotypes related to psychiatric disorders were examined in these distinct rescue mice.ResultsRestoration of Sp4 in forebrain excitatory neurons did not rescue deficient sensorimotor gating nor ketamine-induced hyperlocomotion. Restoration of Sp4 in forebrain GABAergic neurons, however, rescued ketamine-induced hyperlocomotion, but did not rescue deficient sensorimotor gating.ConclusionsOur studies suggest that the Sp4 gene in forebrain GABAergic neurons regulates ketamine-induced hyperlocomotion

The effect of social media communication on consumer perceptions of brands

Researchers and brand managers have limited understanding of the effects social media communication has on how consumers perceive brands. We investigated 504 Facebook users in order to observe the impact of firm-created and user-generated social media communication on brand equity, brand attitude and purchase intention by using a standardized online survey throughout Poland. To test the conceptual model, we analyzed 60 brands across three different industries: non-alcoholic beverages, clothing and mobile network operators. When analyzing the data, we applied the structural equation modeling technique to both investigate the interplay of firm-created and user-generated social media communication and examine industry-specific differences. The results of the empirical studies showed that user-generated social media communication had a positive influence on both brand equity and brand attitude, whereas firm-created social media communication affected only brand attitude. Both brand equity and brand attitude were shown to have a positive influence on purchase intention. In addition, we assessed measurement invariance using a multi-group structural modeling equation. The findings revealed that the proposed measurement model was invariant across the researched industries. However, structural path differences were detected across the models

Maternal effects on anogenital distance in a wild marmot population

Peer reviewedPublisher PD

SmartEx: a case study on user profiling and adaptation in exhibition booths

An investigation into user profiling and adaptation with exhibition booth as a case study is reported. First a review of the field of exhibitions and trade fairs and a summary introduction to adaptation and profiling are given. We then introduce three criteria for the evaluation of exhibition booth: effectiveness, efficiency and affect. Effectiveness is related the amount of information collected, efficiency is a measurement of the time taken to collect the information, and affect is the perception of the experience and the mood booth visitors have during and after their visit. We have selected these criteria to assess adaptive and profiled exhibition booths, we call smart exhibition (SmartEx). The assessment is performed with an experiment with three test conditions (non-profiled/non adaptive, profiled/non-adaptive and profiled adaptive presentations). Results of the experiment are presented along discussion. While there is significant improvements of effectiveness and efficiency between the two-first test conditions, the improvement is not significant for the last test condition, for reasons explained. As for the affect, the results show that it has an under-estimated importance in people minds and that it should be addressed more carefully

Vascular endothelial growth factor in premenopausal women--indicator of the best time for breast cancer surgery?

Timing of surgery in premenopausal patients with breast cancer remains controversial. Angiogenesis is essential for tumour growth and vascular endothelial growth factor (VEGF) is one of the most potent angiogenic cytokines. We aimed to determine whether the study of VEGF in relation to the menstrual cycle could help further the understanding of this issue of surgical intervention. Fourteen premenopausal women were recruited, along with three post-menopausal women, a woman on an oral contraceptive pill and a single male subject. Between eight and 11 samples were taken per person, over one menstrual cycle (over 1 month in the five controls) and analysed for sex hormones and VEGF165. Serum VEGF was significantly lower in the luteal phase and showed a significant negative correlation with progesterone in all 14 premenopausal women. No inter-sample variations of VEGF were noted in the controls. Serum from both phases of the cycle from one subject was added to MCF-7 breast cancer cells; VEGF expression in the supernatant was lower in the cells to which the luteal phase serum was added. The lowering of a potent angiogenic cytokine in the luteal phase suggests a possible decreased potential for micrometastasis establishment in that phase. This fall in VEGF may be an effect of progesterone and should be the focus of future studies