El efecto de la intervención estatal en el mercado de carne vacuna: período 2004-2014

El presente trabajo describe los efectos que tuvo la intervención estatal en el mercado de carne vacuna durante el período 2004-2014. Luego de abordar una base teórica sobre los mecanismos de regulación, el trabajo pone en evidencia la falta de acciones coordinadas entre los actores de la cadena y el gobierno. La problemática se pone de manifiesto con la caída del stock ganadero, la pérdida en el ingreso de divisas y la caída en la competitividad del sector, entre otros. La ausencia de un plan ganadero de largo plazo, el impacto que tienen las regulaciones en el mercado local, el fanatismo por controlar los precios locales en detrimento de las exportaciones, la ausencia de políticas claras, y las propuestas concretas para salir de la actual problemática, son los temas tratados en este trabajo. El objetivo del mismo es generar un análisis que sirva de base para formular políticas concretas que ayuden a salir equilibradamente del exceso de intervención estatal, y encontrar el equilibrio esperado entre el Estado, su regulación, el mercado y los actores privados de la caden

detecting beam offsets in laser welding of closed square butt joints by wavelet analysis of an optical process signal

Abstract Robotized laser beam welding of closed-square-butt joints is sensitive to the positioning of the laser beam with respect to the joint since even a small offset may result in a detrimental lack of sidewall fusion. An evaluation of a system using a photodiode aligned coaxial to the processing laser beam confirms the ability to detect variations of the process conditions, such as when there is an evolution of an offset between the laser beam and the joint. Welding with different robot trajectories and with the processing laser operating in both continuous and pulsed mode provided data for this evaluation. The detection method uses wavelet analysis of the photodetector signal that carries information of the process condition revealed by the plasma plume optical emissions during welding. This experimental data have been evaluated offline. The results show the potential of this detection method that is clearly beneficial for the development of a system for welding joint tracking

COPD Action Plan

Problem/Impact Statements: COPD is a significant driver of patient morbidity and mortality, as well as being associated with increased cost utilization. Acute exacerbations of COPD are a common cause for ED utilization

Targeting HOX/PBX dimers in cancer

The HOX and PBX gene families encode transcription factors that have key roles in establishing the identity of cells and tissues in early development. Over the last 20 years it has become apparent that they are also dysregulated in a wide range of solid and haematological malignancies and have a predominantly pro-oncogenic function. A key mode of transcriptional regulation by HOX and PBX proteins is through their interaction as a heterodimer or larger complex that enhances their binding affinity and specificity for DNA, and there is growing evidence that this interaction is a potential therapeutic target in malignancies that include prostate, breast, renal, ovarian and lung cancer, melanoma, myeloma, and acute myeloid leukaemia. This review summarizes the roles of HOX and PBX genes in cancer and assesses the therapeutic potential of HOX/PBX dimer inhibition, including the availability of biomarkers for its application in precision medicine

Seasonal lipid storage and dietary preferences of native European versus invasive Asian shore crabs

The invasive Asian shore crab Hemigrapsus sanguineus and the native European green crab Carcinus maenas share intertidal habitats along European North Atlantic shores and may compete for food. We evaluated the energy-storing capacities of the 2 species and determined their dietary preferences by means of lipid analysis and fatty acid trophic marker indices. Specimens of both sexes and various sizes were sampled in the rocky intertidal of the island of Helgoland (North Sea) in April, June, August, and October 2015. Total lipids of the midgut glands were significantly higher in H. sanguineus than in C. maenas and followed a distinct seasonal cycle in both sexes (ca. 20−50% of dry mass, DM). The lower lipid contents of C. maenas (ca. 20% of DM) remained at a similar level throughout the seasons. The seasonal differences in the females of H. sanguineus may be due to higher reproductive output and, consequently, lipid turnover, but remain unexplained in males. Trophic indices for Bacillariophyceae, Chlorophyta, and especially Phaeophyceae were higher in H. sanguineus than in C. maenas, suggesting a higher degree of herbivory of the invader. In contrast, the Rhodophyta index was higher in C. maenas. Thus, competition for food between the 2 species will probably be low in habitats rich in macroalgae. The ability of H. sanguineus to utilize mainly energy-poor algae but accumulate high-energy reserves may be an advantage for successfully establishing persistent populations in new habitats