799 research outputs found

    Notes on Factors Affecting Geometrical Arrangement of Tricycle-Type Landing Gear

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    The effects of the geometrical arrangement of tricycle landing gears on various characteristics of an airplane equipped with such landing gear is discussed. The characteristics discussed include directional stability, overturning tendencies, steering and ground handling, shimmy, takeoff, and porpoising. The conclusions are summarized in a table

    Isolation of morphine from toad skin.

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    The need for intra aortic balloon pump support following open heart surgery: risk analysis and outcome

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    <p>Abstract</p> <p>Background</p> <p>The early and intermediate outcome of patients requiring intraaortic balloon pump (IABP) was studied in a cohort of 2697 adult cardiac surgical patients.</p> <p>Methods</p> <p>136 patients requiring IABP (5.04%) support analysed over a 4 year period. Prospective data collection, obtained.</p> <p>Results</p> <p>The overall operative mortality was 35.3%. The "operation specific" mortality was higher on the Valve population.</p> <p>The mortality (%) as per time of balloon insertion was: Preoperative 18.2, Intraopeartive 33.3, postoperative 58.3 (p < 0.05).</p> <p>The incremental risk factors for death were: Female gender (Odds Ratio (OR) = 3.87 with Confidence Intervals (CI) = 1.3-11.6), Smoking (OR = 4.88, CI = 1.23- 19.37), Preoperative Creatinine>120 (OR = 3.3, CI = 1.14-9.7), Cross Clamp time>80 min (OR = 4.16, CI = 1.73-9.98) and IABP insertion postoperatively (OR = 19.19, CI = 3.16-116.47).</p> <p>The incremental risk factors for the development of complications were: Poor EF (OR = 3.16, CI = 0.87-11.52), Euroscore >7 (OR = 2.99, CI = 1.14-7.88), history of PVD (OR = 4.99, CI = 1.32-18.86).</p> <p>The 5 years survival was 79.2% for the CABG population and 71.5% for the valve group. (Hazard ratio = 1.78, CI = 0.92-3.46).</p> <p>Conclusions</p> <p>IABP represents a safe option of supporting the failing heart. The need for IABP especially in a high risk Valve population is associated with early unfavourable outcome, however the positive mid term results further justify its use.</p

    Numerical Study of Magnetoaerodynamic Flow Around a Hemisphere

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    Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/83560/1/AIAA-49278-455.pd

    Transonic small-disturbance theory for lightly loaded cascades

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    Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/76863/1/AIAA-7841-736.pd

    The Role of Parvalbumin-positive Interneurons in Auditory Steady-State Response Deficits in Schizophrenia

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    © The Author(s) 2019. This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.Despite an increasing body of evidence demonstrating subcellular alterations in parvalbumin-positive (PV+) interneurons in schizophrenia, their functional consequences remain elusive. Since PV+ interneurons are involved in the generation of fast cortical rhythms, these changes have been hypothesized to contribute to well-established alterations of beta and gamma range oscillations in patients suffering from schizophrenia. However, the precise role of these alterations and the role of different subtypes of PV+ interneurons is still unclear. Here we used a computational model of auditory steady-state response (ASSR) deficits in schizophrenia. We investigated the differential effects of decelerated synaptic dynamics, caused by subcellular alterations at two subtypes of PV+ interneurons: basket cells and chandelier cells. Our simulations suggest that subcellular alterations at basket cell synapses rather than chandelier cell synapses are the main contributor to these deficits. Particularly, basket cells might serve as target for innovative therapeutic interventions aiming at reversing the oscillatory deficits.Peer reviewe

    Antiepileptic drugs’ tolerability and safety – a systematic review and meta-analysis of adverse effects in dogs

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    <p>Various anti-epileptic drugs (AEDs) are used for the management of idiopathic epilepsy (IE) in dogs. Their safety profile is an important consideration for regulatory bodies, owners and prescribing clinicians. However, information on their adverse effects still remains limited with most of it derived from non-blinded non-randomized uncontrolled trials and case reports.</p><p><span>This poster won third place, which was presented at the Veterinary Evidence Today conference, Edinburgh November 1-3, 2016. </span></p><br /> <img src="https://www.veterinaryevidence.org/rcvskmod/icons/oa-icon.jpg" alt="Open Access" /

    MFA10 (MFA 2010)

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    Catalogue of a culminating student exhibition held at the Mildred Lane Kemper Art Museum in 2010. Content includes Foreword / Buzz Spector -- Thinking as making / Robert Gero -- A new set of conversations / Patricia Olynyk -- MFA 2010 graduates. Clyde Ashby / Aaron Bos-Wahl / Andrew Cozzens / John Early / Ryan James Fabel / Joel Fullerton / Mary Beth Hassan / Wenting Hsu / John Nicholas Hutchings/ Dani Kantrowitz / Larry Keaty / Mamie Korpela / Paola Laterza / Mad Mohre / Emily Moorhead / Jonathan Muehlke / Jessa Richardson / Nicolette Ross / Carlie Trosclair / About the Sam Fox School.https://openscholarship.wustl.edu/books/1007/thumbnail.jp
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