1,467 research outputs found
Statistical relationship between date of sowing and the sorghum shootfly (Atherigona Soccata, Rondani L)
The present study was based on the available data of eleven years for shoot fly from 2000-2010 for kharif season. Different models viz., linear and non linear were tried to fit, Amongst, the linear, quadratic and cubic models produced better coefficient of determination and the models viz., EGG(Shoot fly Egg) =3.760+0.196(DOS) (R2 =0.892) and EGG(Shoot fly Egg) =1.077+1.195(DOS)-0.087(DOS^2), which produced highest R2 (0.896 at p=0.05) with less standard error (0.419) and quadratic model was also the best fit model in determining the oviposition of shoot fly, which explained 89.6 per cent variation in the oviposition of shoot fly for the 7 days after emergence of the sorghum crop. For the dead heart development (14 DAE), the model %DH (% Dead Heart) =3.535+3.104(DOS) found best fit with highest coefficient of determination of 0. 856 and exhibited significant positive relationship with the date of sowing and during 21 DAE the cubic model %DH (% Dead Heart) =10.619+10.115(DOS)-3.466(DOS^2)+0 .321(DOS ^3) had significant coefficient of determination value of 0.988 with least standard error 0.885. The quadratic model during the 28 days after emergence of the crop %DH (% Dead Heart) =-6.234+22.858(DOS) -1.399 (DOS^2) found best fit and produced significant R2 (0.929 at 5 per cent level) and showed better relationship with the date of sowing. It was found that, both linear and non linear relationship exists between dates of sowing and shoot fly of sorghum during kharif season
Apparent age of deposition of meta-carbonate rocks from Sør Rondane Mountains, East Antarctica
第2回極域科学シンポジウム/第31回極域地学シンポジウム 11月17日(木) 国立極地研究所 2階大会議
Rendezvous of Two Robots with Constant Memory
We study the impact that persistent memory has on the classical rendezvous
problem of two mobile computational entities, called robots, in the plane. It
is well known that, without additional assumptions, rendezvous is impossible if
the entities are oblivious (i.e., have no persistent memory) even if the system
is semi-synchronous (SSynch). It has been recently shown that rendezvous is
possible even if the system is asynchronous (ASynch) if each robot is endowed
with O(1) bits of persistent memory, can transmit O(1) bits in each cycle, and
can remember (i.e., can persistently store) the last received transmission.
This setting is overly powerful.
In this paper we weaken that setting in two different ways: (1) by
maintaining the O(1) bits of persistent memory but removing the communication
capabilities; and (2) by maintaining the O(1) transmission capability and the
ability to remember the last received transmission, but removing the ability of
an agent to remember its previous activities. We call the former setting
finite-state (FState) and the latter finite-communication (FComm). Note that,
even though its use is very different, in both settings, the amount of
persistent memory of a robot is constant.
We investigate the rendezvous problem in these two weaker settings. We model
both settings as a system of robots endowed with visible lights: in FState, a
robot can only see its own light, while in FComm a robot can only see the other
robot's light. We prove, among other things, that finite-state robots can
rendezvous in SSynch, and that finite-communication robots are able to
rendezvous even in ASynch. All proofs are constructive: in each setting, we
present a protocol that allows the two robots to rendezvous in finite time.Comment: 18 pages, 3 figure
Self-stabilizing algorithms for Connected Vertex Cover and Clique decomposition problems
In many wireless networks, there is no fixed physical backbone nor
centralized network management. The nodes of such a network have to
self-organize in order to maintain a virtual backbone used to route messages.
Moreover, any node of the network can be a priori at the origin of a malicious
attack. Thus, in one hand the backbone must be fault-tolerant and in other hand
it can be useful to monitor all network communications to identify an attack as
soon as possible. We are interested in the minimum \emph{Connected Vertex
Cover} problem, a generalization of the classical minimum Vertex Cover problem,
which allows to obtain a connected backbone. Recently, Delbot et
al.~\cite{DelbotLP13} proposed a new centralized algorithm with a constant
approximation ratio of for this problem. In this paper, we propose a
distributed and self-stabilizing version of their algorithm with the same
approximation guarantee. To the best knowledge of the authors, it is the first
distributed and fault-tolerant algorithm for this problem. The approach
followed to solve the considered problem is based on the construction of a
connected minimal clique partition. Therefore, we also design the first
distributed self-stabilizing algorithm for this problem, which is of
independent interest
Comparison of chemically estimated depositional ages with zircon SHRIMP ages from metacarbonate rocks in the Sør Rondane Mountains, East Antarctica
第3回極域科学シンポジウム/第32回極域地学シンポジウム 11月30日(金) 国立極地研究所 3階ラウン
EGFR is required for Wnt9a-Fzd9b signalling specificity in haematopoietic stem cells.
Wnt signalling drives many processes in development, homeostasis and disease; however, the role and mechanism of individual ligand-receptor (Wnt-Frizzled (Fzd)) interactions in specific biological processes remain poorly understood. Wnt9a is specifically required for the amplification of blood progenitor cells during development. Using genetic studies in zebrafish and human embryonic stem cells, paired with in vitro cell biology and biochemistry, we determined that Wnt9a signals specifically through Fzd9b to elicit β-catenin-dependent Wnt signalling that regulates haematopoietic stem and progenitor cell emergence. We demonstrate that the epidermal growth factor receptor (EGFR) is required as a cofactor for Wnt9a-Fzd9b signalling. EGFR-mediated phosphorylation of one tyrosine residue on the Fzd9b intracellular tail in response to Wnt9a promotes internalization of the Wnt9a-Fzd9b-LRP signalosome and subsequent signal transduction. These findings provide mechanistic insights for specific Wnt-Fzd signals, which will be crucial for specific therapeutic targeting and regenerative medicine
Eukaryotic-like Ser/Thr Protein Kinases SpkC/F/K Are Involved in Phosphorylation of GroES in the Cyanobacterium Synechocystis
Serine/threonine protein kinases (STPKs) are the major participants in intracellular signal transduction in eukaryotes, such as yeasts, fungi, plants, and animals. Genome sequences indicate that these kinases are also present in prokaryotes, such as cyanobacteria. However, their roles in signal transduction in prokaryotes remain poorly understood. We have attempted to identify the roles of STPKs in response to heat stress in the prokaryotic cyanobacterium Synechocystis sp. PCC 6803, which has 12 genes for STPKs. Each gene was individually inactivated to generate a gene-knockout library of STPKs. We applied in vitro Ser/Thr protein phosphorylation and phosphoproteomics and identified the methionyl-tRNA synthetase, large subunit of RuBisCO, 6-phosphogluconate dehydrogenase, translation elongation factor Tu, heat-shock protein GrpE, and small chaperonin GroES as the putative targets for Ser/Thr phosphorylation. The expressed and purified GroES was used as an external substrate to screen the protein extracts of the individual mutants for their Ser/Thr kinase activities. The mutants that lack one of the three protein kinases, SpkC, SpkF, and SpkK, were unable to phosphorylate GroES in vitro, suggesting possible interactions between them towards their substrate. Complementation of the mutated SpkC, SpkF, and SpkK leads to the restoration of the ability of cells to phosphorylate the GroES. This suggests that these three STPKs are organized in a sequential order or a cascade and they work one after another to finally phosphorylate the GroES
Toll-like receptor 7 is overexpressed in the bladder of Hunner type interstitial cystitis and its activation in the mouse bladder can induce cystitis and bladder pain
自然免疫応答に関する受容体TLR7はHICの膀胱粘膜組織で過剰発現し,マウス膀胱でのTLR7活性化は膀胱痛をともなう炎症を惹起した。よってTLR7を介した反応はHICの病態生理に関与している可能性が示唆された
Role of Esrrg in the Fibrate-Mediated Regulation of Lipid Metabolism Genes in Human ApoA-I Transgenic Mice
We have used a new ApoA-I transgenic mouse model to identify by global gene expression profiling, candidate genes that affect lipid and lipoprotein metabolism in response to fenofibrate treatment. Multilevel bioinformatical analysis and stringent selection criteria (2-fold change, 0% false discovery rate) identified 267 significantly changed genes involved in several molecular pathways. The fenofibrate-treated group did not have significantly altered levels of hepatic human APOA-I mRNA and plasma ApoA-I compared with the control group. However, the treatment increased cholesterol levels to 1.95-fold mainly due to the increase in high-density lipoprotein (HDL) cholesterol. The observed changes in HDL are associated with the upregulation of genes involved in phospholipid biosynthesis and lipid hydrolysis, as well as phospholipid transfer protein. Significant upregulation was observed in genes involved in fatty acid transport and β-oxidation, but not in those of fatty acid and cholesterol biosynthesis, Krebs cycle and gluconeogenesis. Fenofibrate changed significantly the expression of seven transcription factors. The estrogen receptor-related gamma gene was upregulated 2.36-fold and had a significant positive correlation with genes of lipid and lipoprotein metabolism and mitochondrial functions, indicating an important role of this orphan receptor in mediating the fenofibrate-induced activation of a specific subset of its target genes.National Institutes of Health (HL48739 and HL68216); European Union (LSHM-CT-2006-0376331, LSHG-CT-2006-037277); the Biomedical Research Foundation of the Academy of Athens; the Hellenic Cardiological Society; the John F Kostopoulos Foundatio
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