72 Multicenter clinical evaluation of the HeartMate II axial flow left ventricular assist device in patients with severe heart failure: hemodynamic effects, pump performance and quality of life

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/106728/1/ehfs80038-x.pd

Bulk flows in Virasoro minimal models with boundaries

The behaviour of boundary conditions under relevant bulk perturbations is studied for the Virasoro minimal models. In particular, we consider the bulk deformation by the least relevant bulk field which interpolates between the mth and (m-1)st unitary minimal model. In the presence of a boundary this bulk flow induces an RG flow on the boundary, which ensures that the resulting boundary condition is conformal in the (m-1)st model. By combining perturbative RG techniques with insights from defects and results about non-perturbative boundary flows, we determine the endpoint of the flow, i.e. the boundary condition to which an arbitrary boundary condition of the mth theory flows to.Comment: 34 pages, 6 figures. v4: Typo in fig. 2 correcte

Density and distribution of western chimpanzees around a bauxite deposit in the Boé Sector, Guinea-Bissau

Funding: partial support by CEAUL (funded by FCT - Fundação para a Ciência e a Tecnologia, Portugal, through the project UID/MAT/00006/2019) (TAM).The Boé sector in southeast Guinea‐Bissau harbors a population of western chimpanzees (Pan troglodytes verus) that inhabits a mosaic of forest and savanna. The Boé sector contains a substantial bauxite deposit in a region called Ronde Hill, and there are plans for the construction of a mine, which may endanger the chimpanzee population. In 1‐week survey in May 2013, we used the standing crop nest counts method to obtain the number of chimpanzee nests and from that estimate the density and abundance of chimpanzees. We carried out five 1‐km line transects that covered the bauxite deposit and surrounding valleys. We used density surface modeling to analyze habitat preferences, then predicted chimpanzee nest density and distribution based on environmental variables. We found the projected location of the mine partially coincides with an area of high predicted abundances of chimpanzee nests and is surrounded by highly suitable areas for chimpanzees (northeast and southwest). We conclude the mine could have significant direct and indirect effects on this population of chimpanzees whose impacts must be carefully considered and properly mitigated if the mine is built.PostprintPeer reviewe

One-point functions in massive integrable QFT with boundaries

We consider the expectation value of a local operator on a strip with non-trivial boundaries in 1+1 dimensional massive integrable QFT. Using finite volume regularisation in the crossed channel and extending the boundary state formalism to the finite volume case we give a series expansion for the one-point function in terms of the exact form factors of the theory. The truncated series is compared with the numerical results of the truncated conformal space approach in the scaling Lee-Yang model. We discuss the relevance of our results to quantum quench problems.Comment: 43 pages, 20 figures, v2: typos correcte

Form factor expansion for thermal correlators

We consider finite temperature correlation functions in massive integrable Quantum Field Theory. Using a regularization by putting the system in finite volume, we develop a novel approach (based on multi-dimensional residues) to the form factor expansion for thermal correlators. The first few terms are obtained explicitly in theories with diagonal scattering. We also discuss the validity of the LeClair-Mussardo proposal.Comment: 41 pages; v2: minor corrections, v3: minor correction

Variability Across Implanting Centers in Short and Long-Term Mortality and Adverse Events in Patients on HeartMate 3 Support: A Momentum 3 Secondary Analysis

Purpose: We aimed to characterize center-specific variability in HeartMate 3 (HM3) patient survival within the MOMENTUM 3 studies and to examine the correlation between implanting center survival and major adverse events (AEs). Methods: Center HM3 implant volume during the MOMENTUM 3 pivotal (n=515) and continued access protocol (n=1685) trials were tallied. Centers implanting ≤16 HM3 patients (25th percentile) were excluded. De-identified center variability in mortality was assessed at 90 days and 2 years using direct adjusted survival while accounting for key baseline risk factors. The 90-day frequency and 2-year rates of stroke, bleeding, and infection were compared across centers and correlations between survival and event rate variability were assessed. Results: Among 48 centers, 1957 HM3 patients were included in this analysis with site implants ranging between 17 to 103 patients. Patient cohorts differed across the sites by age (average 52-68 years), sex (60-95% male), destination therapy intent (25-100%), and %INTERMACS profile 1-2 (2-81%). At 90 days, center adjusted median mortality was 6.5%, nadiring at ≤3.2% (25th percentile) and peaking at ≥10.5% (75th percentile). Median 2-year center adjusted mortality was 18.6%, nadiring at ≤14.0% and peaking at ≥25.2% (figure A). AEs were also highly variable across centers; centers with low mortality tended to have lower AE rates at 2 years (figure B). Conclusion: Patient characteristics and outcomes were highly variable across MOMENTUM 3 centers despite trial preoperative inclusion/exclusion criteria. Many centers had exemplary risk-adjusted HM3 patient outcomes. Studies are needed to improve our understanding of top performing centers’ best practices as they relate to HM3 care in the pre, interoperative, and chronic support stages in an effort to further improve HM3 LVAD-associated clinical outcomes

A Search for Neutrinos from the Solar hep Reaction and the Diffuse Supernova Neutrino Background with the Sudbury Neutrino Observatory

A search has been made for neutrinos from the hep reaction in the Sun and from the diffus

Combined Analysis of all Three Phases of Solar Neutrino Data from the Sudbury Neutrino Observatory

We report results from a combined analysis of solar neutrino data from all phases of the Sudbury Neutrino Observatory. By exploiting particle identification information obtained from the proportional counters installed during the third phase, this analysis improved background rejection in that phase of the experiment. The combined analysis resulted in a total flux of active neutrino flavors from 8B decays in the Sun of (5.25 \pm 0.16(stat.)+0.11-0.13(syst.))\times10^6 cm^{-2}s^{-1}. A two-flavor neutrino oscillation analysis yielded \Deltam^2_{21} = (5.6^{+1.9}_{-1.4})\times10^{-5} eV^2 and tan^2{\theta}_{12}= 0.427^{+0.033}_{-0.029}. A three-flavor neutrino oscillation analysis combining this result with results of all other solar neutrino experiments and the KamLAND experiment yielded \Deltam^2_{21} = (7.41^{+0.21}_{-0.19})\times10^{-5} eV^2, tan^2{\theta}_{12} = 0.446^{+0.030}_{-0.029}, and sin^2{\theta}_{13} = (2.5^{+1.8}_{-1.5})\times10^{-2}. This implied an upper bound of sin^2{\theta}_{13} < 0.053 at the 95% confidence level (C.L.)