A Non-Probabilistic Model of Relativised Predictability in Physics

Little effort has been devoted to studying generalised notions or models of (un)predictability, yet is an important concept throughout physics and plays a central role in quantum information theory, where key results rely on the supposed inherent unpredictability of measurement outcomes. In this paper we continue the programme started in [1] developing a general, non-probabilistic model of (un)predictability in physics. We present a more refined model that is capable of studying different degrees of "relativised" unpredictability. This model is based on the ability for an agent, acting via uniform, effective means, to predict correctly and reproducibly the outcome of an experiment using finite information extracted from the environment. We use this model to study further the degree of unpredictability certified by different quantum phenomena, showing that quantum complementarity guarantees a form of relativised unpredictability that is weaker than that guaranteed by Kochen-Specker-type value indefiniteness. We exemplify further the difference between certification by complementarity and value indefiniteness by showing that, unlike value indefiniteness, complementarity is compatible with the production of computable sequences of bits.Comment: 10 page

Variation in relapse frequency and the transmission potential of Plasmodium vivax malaria

There is substantial variation in the relapse frequency of Plasmodium vivax malaria, with fast-relapsing strains in tropical areas, and slow-relapsing strains in temperate areas with seasonal transmission. We hypothesize that much of the phenotypic diversity in P. vivax relapses arises from selection of relapse frequency to optimize transmission potential in a given environment, in a process similar to the virulence trade-off hypothesis. We develop mathematical models of P. vivax transmission and calculate the basic reproduction number R0 to investigate how transmission potential varies with relapse frequency and seasonality. In tropical zones with year-round transmission, transmission potential is optimized at intermediate relapse frequencies of two to three months: slower-relapsing strains increase the opportunity for onward transmission to mosquitoes, but also increase the risk of being outcompeted by faster-relapsing strains. Seasonality is an important driver of relapse frequency for temperate strains, with the time to first relapse predicted to be six to nine months, coinciding with the duration between seasonal transmission peaks. We predict that there is a threshold degree of seasonality, below which fast-relapsing tropical strains are selected for, and above which slow-relapsing temperate strains dominate, providing an explanation for the observed global distribution of relapse phenotypes

Electron-phonon coupling in crystalline organic semiconductors: Microscopic evidence for nonpolaronic charge carriers

We consider electron(hole)-phonon coupling in crystalline organic semiconductors, using naphthalene for our case study. Employing a first-principles approach, we compute the changes in the self-consistent Kohn-Sham potential corresponding to different phonon modes and go on to obtain the carrier-phonon coupling matrix elements (vertex functions). We then evaluate perturbatively the quasiparticle spectral residues for electrons at the bottom of the lowest-unoccupied- (LUMO) and holes at the top of the highest-occupied (HOMO) band, respectively obtaining $Z_e\approx 0.74$ and $Z_h\approx 0.78$. Along with the widely accepted notion that the carrier-phonon coupling strengths in polyacenes decrease with increasing molecular size, our results provide a strong microscopic evidence for the previously conjectured nonpolaronic nature of band-like carriers in these systems.Comment: final, published versio

Detection of CO (2-1) and Radio Continuum Emission from the z = 4.4 QSO BRI 1335-0417

We have detected redshifted CO (2-1) emission at 43 GHz and radio continuum emission at 1.47 and 4.86 GHz from the z = 4.4 QSO BRI 1335-0417 using the Very Large Array. The CO data imply optically thick emission from warm (>30 K) molecular gas with a total mass, M(H_2), of 1.5+/-0.3 x10^{11} M_solar, using the Galactic gas mass-to-CO luminosity conversion factor. We set an upper limit to the CO source size of 1.1", and a lower limit of 0.23"x(T_ex/50K)^{-1/2}, where T_ex is the gas excitation temperature. We derive an upper limit to the dynamical mass of 2x10^{10} x sin^{-2} i M_solar, where i is the disk inclination angle. To reconcile the gas mass with the dynamical mass requires either a nearly face-on disk (i < 25deg), or a gas mass-to-CO luminosity conversion factor significantly lower than the Galactic value. The spectral energy distribution from the radio to the rest-frame infrared of BRI 1335-0417 is consistent with that expected from a nuclear starburst galaxy, with an implied massive star formation rate of 2300+/-600 M_solar yr^{-1}.Comment: standard AAS LATEX forma

Limited migration of soluble ionic species in a Siple Dome, Antarctica, ice core

High-resolution (\u3e10 samples a−1) glaciochemical analyses covering the last 110 years from a Siplc Dome, Antarctica, ire core reveal limited migration of certain soluble ionic species (methane sulfonic acid, NO3 − and Mg2+). The observed chemical migration may be due in part to seasonal alternation between less acidic winter (from high sea-salt concentrations) and more acidic summer (from high marine biogenic acid concentrations) layers, common at coastal siles such as Siplc Dome. Exact mechanisms to expla in the migration are unclear, although simple diffusion and gravitational movement are unlikely since new peaks are formed where none previously existed in each case. Initial migration of each species is both shallower and earlier at Siple Dome than at other sites in Antarctica where similar phenomena have been observed, which may be related to the relatively low accumulation rate at Siple Dome (~13.3 cm ice a−1). Migration appears to be limited to either the preceding or following seasonal layer for each species, suggesting that paleoclimatic interpretations based on dala with lower than annual resolution are not likely to be affected

Oscillatory Flows Induced by Microorganisms Swimming in Two-dimensions

We present the first time-resolved measurements of the oscillatory velocity field induced by swimming unicellular microorganisms. Confinement of the green alga C. reinhardtii in stabilized thin liquid films allows simultaneous tracking of cells and tracer particles. The measured velocity field reveals complex time-dependent flow structures, and scales inversely with distance. The instantaneous mechanical power generated by the cells is measured from the velocity fields and peaks at 15 fW. The dissipation per cycle is more than four times what steady swimming would require.Comment: 4 pages, 4 figure

Unravelling the Mysteries of the Leo Ring: An Absorption Line Study of an Unusual Gas Cloud

Since the 1980's discovery of the large (2x10^9 Msun) intergalactic cloud known as the Leo Ring, this object has been the center of a lively debate about its origin. Determining the origin of this object is still important as we develop a deeper understanding of the accretion and feedback processes that shape galaxy evolution. We present HST/COS observations of three sightlines near the Ring, two of which penetrate the high column density neutral hydrogen gas visible in 21 cm observations of the object. These observations provide the first direct measurement of the metallicity of the gas in the Ring, an important clue to its origins. Our best estimate of the metallicity of the ring is ~10% Zsun, higher than expected for primordial gas but lower than expected from an interaction. We discuss possible modifications to the interaction and primordial gas scenarios that would be consistent with this metallicity measurement.Comment: 11 pages, 7 figures, accepted Ap

Systemic mastocytosis with associated myeloproliferative disease and precursor B lymphoblastic leukaemia with t(13;13)(q12;q22) involving FLT3.

Systemic mastocytoses represent neoplastic proliferations of mast cells. In about 20% of cases systemic mastocytoses are accompanied by clonal haematopoietic non-mast cell-lineage disorders, most commonly myeloid neoplasms. A case of systemic mastocytosis carrying the characteristic mutation at codon 816 (D816V) in the KIT gene of mast cells, with two concurrent accompanying clonal haematopoietic non-mast cell-lineage disorders, chronic myeloproliferative disease, unclassifiable and precursor B lymphoblastic leukaemia is documented. Both accompanying clonal haematopoietic non-mast cell-lineage disorders carried the wild-type KIT gene, but had a novel t(13;13)(q12;q22) involving the FLT3 locus at 13q12. The chronic myeloproliferative disease, unclassifiable and the precursor B lymphoblastic leukaemia were cured by syngenous stem cell transplantation, but the systemic mastocytosis persisted for more than 10 years. The additional impact of molecular techniques on the correct diagnosis in haematological malignancies is highlighted, and evidence is provided that, apart from internal tandem duplications and mutations, FLT3 can be activated by translocations