MONOCULAR DEPTH PREDICTION IN PHOTOGRAMMETRIC APPLICATIONS

Abstract. Despite the recent success of learning-based monocular depth estimation algorithms and the release of large-scale datasets for training, the methods are limited to depth map prediction and still struggle to yield reliable results in the 3D space without additional scene cues. Indeed, although state-of-the-art approaches produce quality depth maps, they generally fail to recover the 3D structure of the scene robustly. This work explores supervised CNN architectures for monocular depth estimation and evaluates their potential in 3D reconstruction. Since most available datasets for training are not designed toward this goal and are limited to specific indoor scenarios, a new metric, large-scale synthetic benchmark (ArchDepth) is introduced that renders near real-world scenarios of outdoor scenes. A encoder-decoder architecture is used for training, and the generalization of the approach is evaluated via depth inference in unseen views in synthetic and real-world scenarios. The depth map predictions are also projected in the 3D space using a separate module. Results are qualitatively and quantitatively evaluated and compared with state-of-the-art algorithms for single image 3D scene recovery

Favoritism Toward Foreign and Domestic Brands: A Comparison of Different Theoretical Explanations

Five theoretical approaches can predict favoritism toward domestic and foreign brands. This article applies a contrastive perspective to examine social identity, personal identity, cultural identity, system justification, and categorical cognition theories and their attendant constructs. The authors propose a set of main-effects hypotheses as well as hypotheses related to both product and country moderation effects on attitudes toward and loyalty to domestic and foreign brands. They test the hypotheses on a sample of Chinese consumers with respect to salient brands from 12 product categories. The results indicate that three of the theoretical approaches examined can explain only one side of favoritism—most commonly favoritism toward domestic brands—but not favoritism toward both domestic and foreign brands. Consumer xenocentrism, a concept rooted in system justification theory, seems to provide more consistent predictions for both domestic- and foreign-brand bias

Evaluation of the effectiveness of HDR tone-mapping operators for photogrammetric applications

[EN] The ability of High Dynamic Range (HDR) imaging to capture the full range of lighting in a scene has meant that it is being increasingly used for Cultural Heritage (CH) applications. Photogrammetric techniques allow the semi-automatic production of 3D models from a sequence of images. Current photogrammetric methods are not always effective in reconstructing images under harsh lighting conditions, as significant geometric details may not have been captured accurately within under- and over-exposed regions of the image. HDR imaging offers the possibility to overcome this limitation, however the HDR images need to be tone mapped before they can be used within existing photogrammetric algorithms. In this paper we evaluate four different HDR tone-mapping operators (TMOs) that have been used to convert raw HDR images into a format suitable for state-of-the-art algorithms, and in particular keypoint detection techniques. The evaluation criteria used are the number of keypoints, the number of valid matches achieved and the repeatability rate. The comparison considers two local and two global TMOs. HDR data from four CH sites were used: Kaisariani Monastery (Greece), Asinou Church (Cyprus), Château des Baux (France) and Buonconsiglio Castle (Italy).We would like to thank Kurt Debattista, Timothy Bradley, Ratnajit Mukherjee, Diego Bellido Castañeda and TomBashford Rogers for their suggestions, help and encouragement. We would like to thank the hosting institutions: 3D Optical Metrology Group, FBK (Trento, Italy) and UMR 3495 MAP CNRS/MCC (Marseille, France), for their support during the data acquisition campaigns. This project has received funding from the European Union’s 7 th Framework Programme for research, technological development and demonstration under grant agreement No. 608013, titled “ITN-DCH: Initial Training Network for Digital Cultural Heritage: Projecting our Past to the Future”.Suma, R.; Stavropoulou, G.; Stathopoulou, EK.; Van Gool, L.; Georgopoulos, A.; Chalmers, A. (2016). Evaluation of the effectiveness of HDR tone-mapping operators for photogrammetric applications. Virtual Archaeology Review. 7(15):54-66. https://doi.org/10.4995/var.2016.6319SWORD546671

Successful Control of Acute Myelofibrosis with Lenalidomide

Acute panmyelosis with myelofibrosis (APMF) is a rare, fatal hematological neoplasm that is characterized by the acute onset of cytopenias and fibrosis in the bone marrow in the absence of splenomegaly or fibrosis-related morphological changes in the RBCs. We present the case of a 59-year-old female who presented with a two-month history of anemia, leucopenia and a normal platelet count. The marrow was heavily fibrotic, and no aspirate material could be obtained; the biopsy showed extensive infiltration with small to medium size megakaryocytes, dysplastic changes in the erythroid compartment, and left shift in the myeloid cells. The patient was treated for four months with anabolic steroids (Danazol), growth factors and received regular blood transfusions. At 4 months after diagnosis, the patient was started on Lenalidomide, 10 mg/day for a 21-d-course along with growth factor support. At 6 months after treatment, the patient was transfusion-independent, had normalized blood counts, and, at 32 months on continuous lenalidomide treatment, her needs for growth factor support have been minimized. Repeat bone marrow biopsies showed a patchy distribution of fibrosis with areas of normal cellularity and morphology. To our knowledge, this is the first case for a medication that could reverse the fatal outcome of APMF

Spectroscopic Observations of Convective Patterns in the Atmospheres of Metal-Poor Stars

Convective line asymmetries in the optical spectrum of two metal-poor stars, Gmb1830 and HD140283, are compared to those observed for solar metallicity stars. The line bisectors of the most metal-poor star, the subgiant HD140283, show a significantly larger velocity span that the expectations for a solar-metallicity star of the same spectral type and luminosity class. The enhanced line asymmetries are interpreted as the signature of the lower metal content, and therefore opacity, in the convective photospheric patterns. These findings point out the importance of three-dimensional convective velocity fields in the interpretation of the observed line asymmetries in metal-poor stars, and in particular, urge for caution when deriving isotopic ratios from observed line shapes and shifts using one-dimensional model atmospheres. The mean line bisector of the photospheric atomic lines is compared with those measured for the strong Mg I b1 and b2 features. The upper part of the bisectors are similar, and assuming they overlap, the bottom end of the stronger lines, which are formed higher in the atmosphere, goes much further to the red. This is in agreement with the expected decreasing of the convective blue-shifts in upper atmospheric layers, and compatible with the high velocity redshifts observed in the chromosphere, transition region, and corona of late-type stars.Comment: 27 pages, LaTeX; 10 Figures (14 PostScript files); to be published in The Astrophysical Journa

Quantitative RT-PCR luminometric hybridization assay with an RNA-internal standard for cytokeratin-19 mRNA in peripheral blood of patients with breast cancer. Clin Biochem

6 normal PBMC and is highly specific as none of the 26 healthy controls tested had detectable CK-19 mRNA levels, while 10 out of 14 (71.4%) and 9 out of 37 (24.3%) patients with stage IV and stage I/II breast cancer, respectively, were tested positive. Conclusion: The developed quantitative RT-PCR hybridization assay for CK-19 is reproducible, highly sensitive and specific, and can be used for a large-scale prospective evaluation of clinical samples

Electrode fabrication and interface optimization for imaging of evoked peripheral nervous system activity with electrical impedance tomography (EIT)

Objective. Non-invasive imaging techniques are undoubtedly the ideal methods for continuous monitoring of neural activity. One such method, fast neural electrical impedance tomography (EIT) has been developed over the past decade in order to image neural action potentials with non-penetrating electrode arrays. Approach. The goal of this study is two-fold. First, we present a detailed fabrication method for silicone-based multiple electrode arrays which can be used for epicortical or neural cuff applications. Secondly, we optimize electrode material coatings in order to achieve the best accuracy in EIT reconstructions. Main results. The testing of nanostructured electrode interface materials consisting of platinum, iridium oxide, and PEDOT:pTS in saline tank experiments demonstrated that the PEDOT:pTS coating used in this study leads to more accurate reconstruction dimensions along with reduced phase separation between recording channels. The PEDOT:pTS electrodes were then used in vivo to successfully image and localize the evoked activity of the recurrent laryngeal fascicle from within the cervical vagus nerve. Significance. These results alongside the simple fabrication method presented here position EIT as an effective method to image neural activity

Business models and consumers' value proposition for PEDs value generation by PEDs: best practices case study book

Executive Summary: The EU's SET Plan has proposed the development of Positive Energy Districts (PEDs) to achieve the transition towards a more sustainable energy system through the adoption of renewable energy technologies and energy efficiency measures. PEDs are envisioned to be neighbourhoods that utilise such technologies and create an environment that enables citizens to lead environmentally‐friendly lifestyles. At their core, PEDs create value across three sustainability dimensions: environmental, social, and economic. PEDs and PED‐like projects can be developed in a variety of ways and are a product of the physical, social, and economic characteristics of the environment. Innovative business models – the configurations in which value is created, delivered, and captured – are integral to leveraging these contextual characteristics in order to achieve the goals of PEDs. This study aims to identify best practice cases and categorise them into archetypes of business models operating in PEDs in order to summarise the opportunities available in PED creation. The authors synthesise existing literature in the area of sustainable business models to develop a conceptual framework that analyses the extent to which the value dimensions of business models address the economic, social, and environmental dimensions of sustainability, with a focus on PEDs. This allows the building blocks of the original business model canvas to be modified and extended. The authors use a qualitative analytical approach, to a set of selected European cases, through the lens of the conceptual framework to identify business model archetypes of PEDs and PED‐like projects

PHOTOMATCH: AN OPEN-SOURCE MULTI-VIEW and MULTI-MODAL FEATURE MATCHING TOOL for PHOTOGRAMMETRIC APPLICATIONS

Automatic feature matching is a crucial step in Structure-from-Motion (SfM) applications for 3D reconstruction purposes. From an historical perspective we can say now that SIFT was the enabling technology that made SfM a successful and fully automated pipeline. SIFT was the ancestor of a wealth of detector/descriptor methods that are now available. Various research activities have tried to benchmark detector/descriptors operators, but a clear outcome is difficult to be drawn. This paper presents an ISPRS Scientific Initiative aimed at providing the community with an educational open-source tool (called PhotoMatch) for tie point extractions and image matching. Several enhancement and decolorization methods can be initially applied to an image dataset in order to improve the successive feature extraction steps. Then different detector/descriptor combinations are possible, coupled with different matching strategies and quality control metrics. Examples and results show the implemented functionality of PhotoMatch which has also a tutorial for shortly explaining the implemented methods

Gene expression profile of circulating tumor cells in breast cancer by RT-qPCR

<p>Abstract</p> <p>Background</p> <p>Circulating tumor cells (CTCs) have been associated with prognosis especially in breast cancer and have been proposed as a liquid biopsy for repeated follow up examinations. Molecular characterization of CTCs is difficult to address since they are very rare and the amount of available sample is very limited.</p> <p>Methods</p> <p>We quantified by RT-qPCR <it>CK-19, MAGE-A3, HER-2, TWIST1, hTERT α+β+</it>, and <it>mammaglobin </it>gene transcripts in immunomagnetically positively selected CTCs from 92 breast cancer patients, and 28 healthy individuals. We also compared our results with the CellSearch system in 33 of these patients with early breast cancer.</p> <p>Results</p> <p>RT-qPCR is highly sensitive and specific and can detect the expression of each individual gene at the one cell level. None of the genes tested was detected in the group of healthy donors. In 66 operable breast cancer patients, <it>CK-19 </it>was detected in 42.4%, <it>HER-2 </it>in 13.6%, <it>MAGE-A3 </it>in 21.2%, <it>hMAM </it>in 13.6%, <it>TWIST-1 </it>in 42.4%, and <it>hTERT α+β+ </it>in 10.2%. In 26 patients with verified metastasis, <it>CK-19 </it>was detected in 53.8%, <it>HER-2 </it>in 19.2%, <it>MAGE-A3 </it>in 15.4%, <it>hMAM </it>in 30.8%, <it>TWIST-1 </it>in 38.5% and <it>hTERT </it>α⁺β⁺in 19.2%. Our preliminary data on the comparison between RT-qPCR and CellSearch in 33 early breast cancer patients showed that RT-qPCR gives more positive results in respect to CellSearch.</p> <p>Conclusions</p> <p>Molecular characterization of CTCs has revealed a remarkable heterogeneity of gene expression between breast cancer patients. In a small percentage of patients, CTCs were positive for all six genes tested, while in some patients only one of these genes was expressed. The clinical significance of these findings in early breast cancer remains to be elucidated when the clinical outcome for these patients is known.</p