113 research outputs found

    FPGA Based Massage Display System Improvement Using Scanning Technique To Minimize Power Consumption

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    This paper presents a field programmable gate array (FPGA) based embedded system for low power message display. Scanning technique is used to minimize the power consumption. The experiment is conducted on 30 seven segments where an field programmable gate array based intelligent controller scans all the display elements continuously at a certain speed to ensure only one display unit is on and other are off at a given time but human eyes cannot detect it. The test result shows the significant reduction of power consumption over static display system. That is very essential of power efficient solution for the portable electronic system

    A Retrospective Cohort Analysis of Pediatric Tuberculosis in North Carolina, 1994-2002

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    Background: The incidence of pediatric tuberculosis (TB) in North Carolina decreased from the mid 1990s to 200l. In 2002, the number of pediatric TB cases increased from 9 in 2001 to 32 in 2002, representing more than a 250% increase. Objective: To describe the epidemiology and clinical characteristics of pediatric TB in North Carolina and identify factors contributing to the rise in tuberculosis cases among children less than 15 years of age. Methods: Retrospective review of TB surveillance data and local health department records of all reported pediatric TB cases and their source case between the years 1994 and 2002. Results: 180 cases of pediatric TB were reported from 1994-2002. The incidence of pediatric TB increased from 0.53 to 1.85 per 100,000 from 2001 to 2002. TB case rates in 2002 were higher in children less than 5 years of age (3.05 per 100,000) compared to children 5-14 years of age (1.28 per 100,000). TB case rates were 10- to 44-fold higher among minority children compared to non-Hispanic white children. Although there was no significant increase in the incidence of TB in the Hispanic pediatric population, there was a significant increase in the proportion of Hispanic children with tuberculosis (p-value =.04). Children with a foreign association accounted for an increasing proportion of pediatric TB cases over time, however, the increase was not statistically significant (p-value = 0.09). Transmission of TB to children could have been prevented in 6.75% of cases had a source case identified the child as a contact, and in 11.7% of cases had the source case completed prophylaxis for latent TB infection. TB disease may have been prevented in 7.2% of cases had the contact investigation not been delayed, 2.2% of cases had children with latent TB infection completed prophylaxis, and in 4.4% of cases had child contacts <5 years of age with a negative PPD taken or received prophylaxis. Overall, 51/180 cases (28.3%) might have been prevented had appropriate measures been taken. Conclusion: The incidence of pediatric TB increased significantly from 2001 to 2002. TB in the minority population continues to be a problem. TB in children with a foreign-association is increasing. Improvements in contact investigations and completion of prophylaxis for LTBI may reduce the incidence of pediatric TB.Master of Public Healt

    EFFECT OF FEEDING MILK REPLACER ON GROWTH PERFORMANCE OF YAK CALVES

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    ABSTRACT An investigation was carried out on 18 numbers of new bor

    Bio-medical waste management in different hospitals of Guwahati and its effect on environment

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    Biomedical waste may be defined as the waste which is produced during the diagnosis, research activities, treatment of patients, treatment of animals, production and testing of biological product and including articles as mentioned in schedule I of the Biomedical Waste (Management and handling) (second amendment) Rules 2000, as per Ministry of&nbsp; Environment and Forests notification. Proper treatment, handling, and disposal of biomedical wastes is essential for healthcare infection control program. There may be a high risk of infections in patients due to the poor management of biomedical waste which can lead to antibiotic resistance. It is not only the health of the patient, but also the health of persons who are associated with health care industry equally important. This article speaks about how the hospitals present in Guwahati treat their waste material and the effect of the waste in the environmen

    Delta excitation in K^+-nucleus collisions

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    We present calculations for \Delta excitation in the (K^+,K^+) reaction in nuclei. The background from quasielastic K^+ scattering in the \Delta region is also evaluated and shown to be quite small in some kinematical regions, so as to allow for a clean identification of the \Delta excitation strength. Nuclear effects tied to the \Delta renormalization in the nucleus are considered and the reaction is shown to provide new elements to enrich our knowledge of the \Delta properties in a nuclear medium.Comment: 11 pages, 6 figures, LaTe

    ERP systems introduction and internal auditing legitimacy: An institutional analysis

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    In this paper, the authors examine how the internal audit function (IAF) maintains its legitimacy when enterprise resource planning (ERP) systems are introduced. This work centers on an in-depth case study of a multinational bank and finds that ERP systems impose an institutional logic of control based on interlinked assumptions. These assumptions motivate changes in the practice and structure of the IAF to become an integrated and comprehensive function to maintain its legitimacy

    Isolated hypercholesterolemia leads to steatosis in the liver without affecting the pancreas

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    Abstract Background Lipid accumulation in the liver and pancreas is primarily caused by combined hyperlipidemia. However, the effect of isolated hypercholesterolemia without hypertriglyceridemia is not fully described. Therefore, our aim was to investigate whether hypercholesterolemia alone leads to alterations both in hepatic and pancreatic lipid panel and histology in rats. Methods Male Wistar rats were fed with 2% cholesterol +0.25% cholate-supplemented diet or standard chow for 12 weeks. Blood was collected at weeks 0, 4, 8 and 12 to measure serum cholesterol and triglyceride levels. At week 12, both the pancreas and the liver were isolated for further histological and biochemical analysis. Hepatic and plasma fatty acid composition was assessed by gas chromatography. Expression of mRNA of major enzymes involved in saturated/unsaturated fatty acid synthesis was analyzed by qPCR. In separate experiments serum enzyme activities and insulin levels were measured at week 9. Results At week 12, rats fed with 2% cholesterol +0.25% cholate-supplemented diet were characterized by elevated serum cholesterol (4.09 ± 0.20 vs. 2.89 ± 0.22 mmol/L, *p < 0.05) while triglyceride (2.27 ± 0.05 vs. 2.03 ± 0.03 mmol/L) and glucose levels (5.32 ± 0.14 vs. 5.23 ± 0.10 mmol/L) remained unchanged. Isolated hypercholesterolemia increased hepatic lipid accumulation, hepatic cholesterol (5.86 ± 0.22 vs. 1.60 ± 0.15 ng/g tissue, *p < 0.05) and triglyceride contents (19.28 ± 1.42 vs. 6.78 ± 0.71 ng/g tissue, *p < 0.05), and hepatic nitrotyrosine level (4.07 ± 0.52 vs. 2.59 ± 0.31 ng/mg protein, *p < 0.05). The histology and tissue lipid content of the pancreas was not affected. Serum total protein level, alanine aminotransferase (ALT) and aspartate aminotransferase (AST) activities remained unchanged in response to isolated hypercholesterolemia while serum alkaline phosphatase activity (ALP) significantly increased. Plasma insulin levels did not change in response to isolated hypercholesterolemia suggesting an intact endocrine function of the pancreas. Isolated hypercholesterolemia caused a significantly increased hepatic and serum fatty acid level associated with a marked alteration of fatty acid composition. Hepatic expression of Δ9-desaturase (SCD1) was increased 4.92×, while expression of Δ5-desaturase and Δ6-desaturase were decreased (0.447× and 0.577×, respectively) due to isolated hypercholesterolemia. Conclusions Isolated hypercholesterolemia leads to hepatic steatosis and marked alterations in the hepatic lipid profile without affecting the pancreas. Altered fatty acid profile might mediate harmful effects of cholesterol in the liver

    The Protein Network Surrounding the Human Telomere Repeat Binding Factors TRF1, TRF2, and POT1

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    Telomere integrity (including telomere length and capping) is critical in overall genomic stability. Telomere repeat binding factors and their associated proteins play vital roles in telomere length regulation and end protection. In this study, we explore the protein network surrounding telomere repeat binding factors, TRF1, TRF2, and POT1 using dual-tag affinity purification in combination with multidimensional protein identification technology liquid chromatography - tandem mass spectrometry (MudPIT LC-MS/MS). After control subtraction and data filtering, we found that TRF2 and POT1 co-purified all six members of the telomere protein complex, while TRF1 identified five of six components at frequencies that lend evidence towards the currently accepted telomere architecture. Many of the known TRF1 or TRF2 interacting proteins were also identified. Moreover, putative associating partners identified for each of the three core components fell into functional categories such as DNA damage repair, ubiquitination, chromosome cohesion, chromatin modification/remodeling, DNA replication, cell cycle and transcription regulation, nucleotide metabolism, RNA processing, and nuclear transport. These putative protein-protein associations may participate in different biological processes at telomeres or, intriguingly, outside telomeres
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