Gypsy moths and American dog ticks: Space partners

An experiment intended for the space shuttle and designed to investigate the effects of weightlessness and total darkness on gypsy moth eggs and engorged American dog ticks is described. The objectives are: (1) to reevaluate the effects of zero gravity on the termination of diapause/hibernation of embryonated gypsy moth eggs, (2) to determine the effect of zero gravity on the ovipositions and subsequent hatch from engorged female American dog ticks that have been induced to diapause in the laboratory, and (3) to determine whether morphological or biochemical changes occur in the insects under examination. Results will be compared with those from a similar experiment conducted on Skylab 4

Sequential primed kinases create a damage-responsive phosphodegron on Eco1.

Sister-chromatid cohesion is established during S phase when Eco1 acetylates cohesin. In budding yeast, Eco1 activity falls after S phase due to Cdk1-dependent phosphorylation, which triggers ubiquitination by SCF(Cdc4). We show here that Eco1 degradation requires the sequential actions of Cdk1 and two additional kinases, Cdc7-Dbf4 and the GSK-3 homolog Mck1. These kinases recognize motifs primed by previous phosphorylation, resulting in an ordered sequence of three phosphorylation events on Eco1. Only the latter two phosphorylation sites are spaced correctly to bind Cdc4, resulting in strict discrimination between phosphates added by Cdk1 and by Cdc7. Inhibition of Cdc7 by the DNA damage response prevents Eco1 destruction, allowing establishment of cohesion after S phase. This elaborate regulatory system, involving three independent kinases and stringent substrate selection by a ubiquitin ligase, enables robust control of cohesion establishment during normal growth and after stress

Spray drag effect of fluidized sand for a supersonic vehicle

This paper deals with fluidized sand simulation in order to estimate the impact of sand particle motion on the BLOODHOUND SuperSonic Car (SSC) drag forces, such phenomenon is known as a spray drag effect. A gas-particle model is used to simulate the sand particles that rise from the ground because of the strong shockwave-desert surface interaction. A finite volume scheme is used to discretise the continuous model with a special treatment of the solid phase equations. An indefinitely differentiable and anisotropic limiter to reinforce the method stability and reduce any excessive smearing is applied. To estimate the area where sand particles are detached from the ground, a criterion based on pressure change is proposed. The model is first validated on a curved 90 bend test case with comparison to experimental results and then applied to the supersonic car

An investigation of neural networks for aerodynamic predictions

This work proposes a novel multi-output neural network for the prediction of the lift coefficient of aerofoils using inviscid compressible flow data. Contrary to existing neural networks that are designed to predict aerodynamic quantities of interest, the proposed network considers as output the pressure at a number of selected points on the aerofoil surface. The proposed approach is compared against the more traditional network where the lift coefficient is directly the only output of the network. Furthermore, a detailed comparison of the proposed neural network against the popular proper orthogonal decomposition method is presented. The numerical results, involving high dimensional problems with flow and geometric parameters, show the benefits of the proposed approach

The experimental observation of Beliaev damping in a Bose condensed gas

We report the first experimental observation of Beliaev damping of a collective excitation in a Bose-condensed gas. Beliaev damping is not predicted by the Gross-Pitaevskii equation and so this is one of the few experiments that tests BEC theory beyond the mean field approximation. Measurements of the amplitude of a high frequency scissors mode, show that the Beliaev process transfers energy to a lower lying mode and then back and forth between these modes. These characteristics are quite distinct from those of Landau damping, which leads to a monotonic decrease in amplitude. To enhance the Beliaev process we adjusted the geometry of the magnetic trapping potential to give a frequency ratio of 2 to 1 between two of the scissors modes of the condensate. The ratios of the trap oscillation frequencies $\omega_y / \omega_x$ and $\omega_z / \omega_x$ were changed independently, so that we could investigate the resonant coupling over a range of conditions.Comment: 4 pages including 5 fig

A hierarchical mesh refinement technique for global 3-D spherical mantle convection modelling

A method for incorporating multi-resolution capabilities within pre-existing global 3-D spherical mantle convection codes is presented. The method, which we term "geometric multigrid refinement", is based upon the application of a multigrid solver on non

A Reanalysis of theUltraviolet Extinction from Interstellar Dust in the Large Magellanic Cloud

We have reanalyzed the Large Magellanic Cloud's (LMC) ultraviolet (UV) extinction using data from the IUE final archive. Our new analysis takes advantage of the improved signal--to--noise of the IUE NEWSIPS reduction, the exclusion of stars with very low reddening, the careful selection of well matched comparison stars, and an analysis of the effects of Galactic foreground dust. Differences between the average extinction curves of the 30 Dor region and the rest of the LMC are reduced compared to previous studies. We find that there is a group of stars with very weak 2175 Ang. bumps that lie in or near the region occupied by the supergiant shell, LMC 2, on the southeast side of 30 Dor. The average extinction curves inside and outside LMC 2 show a very significant difference in 2175 Ang. bump strength, but their far--UV extinctions are similar. While it is unclear whether or not the extinction outside the LMC 2 region can be fit with the relation of Cardelli, Clayton and Mathis (CCM), sightlines near LMC 2 cannot be fit with CCM due to their weak 2175 Ang. bumps. While the extinction properties seen in the LMC lie within the range of properties seen in the Galaxy, the correlations of UV extinction properties with environment seen in the Galaxy do not appear to hold in the LMC.Comment: 29 pages, 10 figures, to be published in Ap

Using schedulers to test probabilistic distributed systems

This is the author's accepted manuscript. The final publication is available at Springer via http://dx.doi.org/10.1007/s00165-012-0244-5. Copyright © 2012, British Computer Society.Formal methods are one of the most important approaches to increasing the confidence in the correctness of software systems. A formal specification can be used as an oracle in testing since one can determine whether an observed behaviour is allowed by the specification. This is an important feature of formal testing: behaviours of the system observed in testing are compared with the specification and ideally this comparison is automated. In this paper we study a formal testing framework to deal with systems that interact with their environment at physically distributed interfaces, called ports, and where choices between different possibilities are probabilistically quantified. Building on previous work, we introduce two families of schedulers to resolve nondeterministic choices among different actions of the system. The first type of schedulers, which we call global schedulers, resolves nondeterministic choices by representing the environment as a single global scheduler. The second type, which we call localised schedulers, models the environment as a set of schedulers with there being one scheduler for each port. We formally define the application of schedulers to systems and provide and study different implementation relations in this setting

Is there a correlation between infection control performance and other hospital quality measures?

Quality measures are increasingly reported by hospitals to the Centers for Medicare and Medicaid Services (CMS), yet there may be tradeoffs in performance between infection control (IC) and other quality measures. Hospitals that performed best on IC measures did not perform well on most CMS non–IC quality measures

Simulations of thermal Bose fields in the classical limit

We demonstrate that the time-dependent projected Gross-Pitaevskii equation derived earlier [Davis, et al., J. Phys. B 34, 4487 (2001)] can represent the highly occupied modes of a homogeneous, partially-condensed Bose gas. We find that this equation will evolve randomised initial wave functions to equilibrium, and compare our numerical data to the predictions of a gapless, second-order theory of Bose-Einstein condensation [S. A. Morgan, J. Phys. B 33, 3847 (2000)]. We find that we can determine the temperature of the equilibrium state when this theory is valid. Outside the range of perturbation theory we describe how to measure the temperature of our simulations. We also determine the dependence of the condensate fraction and specific heat on temperature for several interaction strengths, and observe the appearance of vortex networks. As the Gross-Pitaevskii equation is non-perturbative, we expect that it can describe the correct thermal behaviour of a Bose gas as long as all relevant modes are highly occupied.Comment: 15 pages, 12 figures, revtex4, follow up to Phys. Rev. Lett. 87 160402 (2001). v2: Modified after referee comments. Extra data added to two figures, section on temperature determination expande