Drahtwurmregulierung in Kartoffeln mit dem ‚Attract and Kill‘ Verfahren

Er werden zweijährige Ergebnisse aus acht Feldversuchen zur Regulierung des Drahtwurms in Ökokartoffeln mit Hilfe des Attract & Kill Verfahrens auf Basis von Metarhizium brunneum (Attracap) vorgestellt. Im ersten Versuchsjahr wurde eine signifikant befallsreduzierende Wirkung bei insgesamt vergleichsweise niedrigem Befallsdruck insbesondere nach Punktablage festgestellt. Der maximal ermittelte Wirkungsgrad von Attracap betrug 60%. Ein Zusammenhang ziwschen Ausgangsbefall zur Pflanzung und der Knollenschädigung zur Ernte wurde nicht festgestellt. Die Versuche 2018 werden derzeit ausgewertet und auf dem Poster vorgestellt

26-Gb/s DMT Transmission Using Full C-Band Tunable VCSEL for Converged PONs

Wavelength division multiplex (WDM) passive optical network (PON) is considered for converged fixed mobile broadband access networking. We propose to utilize low-cost tunable lasers at the remote sites, together with a centralized wavelength locker. Practical implementations require a transparently added downstream signaling channel and upstream per-channel pilot tones for channel tagging and remote wavelength control. We demonstrate, for the first time, 26-Gbps discrete multitone transmission modulated on a low-cost wide tunable vertical surface emitting laser over up to 40 km of standard single-mode fiber. The results confirm that converged fixed mobile WDM-PON systems based on low-cost lasers carrying discrete multitone modulation are a technically viable approach

The genomic and transcriptional landscape of primary central nervous system lymphoma

Primary lymphomas of the central nervous system (PCNSL) are mainly diffuse large B-cell lymphomas (DLBCLs) confined to the central nervous system (CNS). Molecular drivers of PCNSL have not been fully elucidated. Here, we profile and compare the whole-genome and transcriptome landscape of 51 CNS lymphomas (CNSL) to 39 follicular lymphoma and 36 DLBCL cases outside the CNS. We find recurrent mutations in JAK-STAT, NFkB, and B-cell receptor signaling pathways, including hallmark mutations in MYD88 L265P (67%) and CD79B (63%), and CDKN2A deletions (83%). PCNSLs exhibit significantly more focal deletions of HLA-D (6p21) locus as a potential mechanism of immune evasion. Mutational signatures correlating with DNA replication and mitosis are significantly enriched in PCNSL. TERT gene expression is significantly higher in PCNSL compared to activated B-cell (ABC)-DLBCL. Transcriptome analysis clearly distinguishes PCNSL and systemic DLBCL into distinct molecular subtypes. Epstein-Barr virus (EBV)+ CNSL cases lack recurrent mutational hotspots apart from IG and HLA-DRB loci. We show that PCNSL can be clearly distinguished from DLBCL, having distinct expression profiles, IG expression and translocation patterns, as well as specific combinations of genetic alterations

Retrospective evaluation of whole exome and genome mutation calls in 746 cancer samples

Funder: NCI U24CA211006Abstract: The Cancer Genome Atlas (TCGA) and International Cancer Genome Consortium (ICGC) curated consensus somatic mutation calls using whole exome sequencing (WES) and whole genome sequencing (WGS), respectively. Here, as part of the ICGC/TCGA Pan-Cancer Analysis of Whole Genomes (PCAWG) Consortium, which aggregated whole genome sequencing data from 2,658 cancers across 38 tumour types, we compare WES and WGS side-by-side from 746 TCGA samples, finding that ~80% of mutations overlap in covered exonic regions. We estimate that low variant allele fraction (VAF < 15%) and clonal heterogeneity contribute up to 68% of private WGS mutations and 71% of private WES mutations. We observe that ~30% of private WGS mutations trace to mutations identified by a single variant caller in WES consensus efforts. WGS captures both ~50% more variation in exonic regions and un-observed mutations in loci with variable GC-content. Together, our analysis highlights technological divergences between two reproducible somatic variant detection efforts

LIGHT ENVIRONMENT AND PHOTOSYNTHESIS OF AN UNDERSTORE AND A PIONNER SPECIES FROM PREMONTANE RAINFOREST OF COSTA RlCA

Light environments of gap and understorey microsites were examined in a premontane wet forest area at the Reserva Biológica Alberto M1. Brenes (RBAB), 40 km NW of San Ramón, Alajuela, Costa Rica. The light conditions varied both, in spatial and temporal pattems. Understorey sites were characterized by a low dimlight background (1 5-1 8 p o l m-2s-' ) occasionally interrupted by short lightfletcks of direct irradiante ( 4 0 0 pmol m-2s-' )

Light environment and photosynthesis of an understore and a pionner species from premontane rainforest of costa rlca

Light environments of gap and understorey microsites were examined in a premontane wet forest area at the Reserva Biológica Alberto M1. Brenes (RBAB), 40 km NW of San Ramón, Alajuela, Costa Rica. The light conditions varied both, in spatial and temporal pattems. Understorey sites were characterized by a low dimlight background (1 5-1 8 p o l m-2s-' ) occasionally interrupted by short lightfletcks of direct irradiante ( 4 0 0 pmol m-2s-' )

Food cue-induced craving in individuals with bulimia nervosa and binge-eating disorder

Individuals with bulimia nervosa (BN) or binge-eating disorder (BED) experience more frequent and intense food cravings than individuals without binge eating. However, it is currently unclear whether they also show larger food cue-induced increases in craving (i.e., food cue reactivity) than those without binge eating, as suggested by conditioning theories of binge eating. Agroupof individuals with BN or BED (binge-eatinggroup, n = 27) and agroupof individuals with low trait food craving scores and without binge eating (controlgroup, n = 19) reported their current food craving before and after a food cue exposure. Although food craving intensity significantly increased in bothgroups, this increase was significantly stronger in the binge-eatinggroupthan in the controlgroup. This result is in line with conditioning models of binge eating that propose that food cues are conditioned stimuli that elicit a conditioned response (e.g., food craving) and that this association is stronger in individuals with binge eating. As food craving increased in individuals with low trait food craving scores as wellalthough to a lesser extentprevious null results might be explained by methodological considerations such as not screening control participantsfortrait food craving.(VLID)282537