Análise de variáveis fisiológicas e perceptuais durante combates de Brazilian Jiu-Jitsu

Objetivo: analisar o comportamento de marcadores fisiológicos e perceptuais de carga interna em combates sucessivos de Jiu-Jitsu e verificar possíveis correlações entre essas variáveis. Método: participaram do estudo cinco lutadores (28,4 ± 5 anos; 175 ± 6 cm; 82,4 ± 7 kg; % gordura 12,7 ± 3). Todos realizaram três combates com duração e intervalos de seis minutos. Foram analisados em cada combate: Frequência Cardíaca (FC), Percepção Subjetiva de Esforço (PSE) e Lactato (LAC). Resultados e considerações finais: o comportamento da FC (combate I: 85%; combate II: 86%; combate III: 90% da máxima predita), PSE (combate I: 5,6±3; combate II: 6,4 ± 2; combate III: 8 ± 3) e LAC (combate I: 4,6 ± 1,5; combate II: 7,3 ± 2,2; combate III: 6,12 ± 2) foram semelhantes ao longo das lutas. Foi observada correlação entre FC e LAC no primeiro combate (r = 0,97 p < 0,01) FC e PSE no último combate (r = 0,89 p < 0,05). Conclui-se que combates sucessivos de jiu-jitsu apresentam alta demanda cardiovascular e perceptual, e as variáveis analisadas tiveram correlação somente em alguns combates, o que reforça a necessidade do uso de marcadores fisiológicos e perceptuais de avaliação para análise da carga interna imposta a esses atletas

Susceptibilidad in vitro a los medicamentos anti-tuberculosos de aislados de cepas del complejo Mycobacterium tuberculosis obtenidos a partir de lobos marinos

Mycobacteria strains belonging to the Mycobacterium tuberculosis complex were isolated from seals found in the South Atlantic. The animals were received in Mundo Marino installations and treated for Mycobacterium tuberculosis complex by conventional therapy of intensive care and enriched food supply; however, in all cases treatment failed. Necropsies of all animals revealed extensive lesions compatible with tuberculosis involving lungs, liver, spleen and lymphatic nodes. Classical biochemical methods as well as molecular techniques using the IS6110 probes were performed for mycobacterial identification. Furthermore, the LCx M. tuberculosis assay (Abbott Laboratories) identified all strains as Mycobacterium tuberculosis complex members. The in vitro susceptibility pattern was examined in mycobacterial strains isolated from seven seals and in 3 reference strains--BCG, H37Rv (M. tuberculosis) and AN5 (Mycobacterium bovis)--to 4 medications--isoniazid, rifampin, streptomycin and ethambutol. Minimal inhibitory drug concentrations were determined by the Mycobacterial Growth Indicator Tube (BD Argentina) method and a microdilution and colorimetric assay using 3-(4-5 dimethyltiazol-2)-2,5 diphenyltetrazolium bromide. All the isolates and the reference strains BCG and AN5 were inhibited by MIC values similar to those of H37Rv with good agreement obtained by both techniques. These findings suggest that a therapeutic regimen aimed to seals diagnosed with tuberculosis play an important role in the prevention of tuberculosis transmission from infected animals to humans that are in routine contact with them.Se han hallado cepas de micobacterias aisladas de lobos marinos del Atlántico sur y pertenecen al complejo de Mycobacterium tuberculosis. Los animales se recibieron en las instalaciones del Oceanario Mundo Marino y fueron tratados apropiadamente para su recuperación con la terapia convencional, cuidados intensivos y suplemento alimentario pero no se observó mejoría en su estado general. Se practicaron necropsias en todos los animales y se observaron lesiones extensas compatibles con tuberculosis en pulmones, hígado, bazo y ganglios linfáticos. Para la identificación de las micobacterias, se realizaron pruebas bioquímicas y técnicas de biología molecular con la sonda IS6110. Además, se identificaron todas las cepas como pertenecientes al complejo M. tuberculosis mediante el equipo LCx M. tuberculosis Assay (Abbott Laboratories). El objetivo de este estudio fue determinar in vitro la sensibilidad de las cepas patrón BCG, H37Rv (M. tuberculosis) y AN5 (Mycobacterium bovis) y la de las siete aisladas de lobos marinos a isoniacida, rifampicina, estreptomicina y etambutol. La concentración inhibitoria mínima (CIM) de las drogas antituberculosas se llevó a cabo con el equipo Mycobacterial Growth Indicator Tube (MGIT, BD, Argentina) y la microdilución con el ensayo colorimétrico con bromuro de 3-(4-5 dimetiltiazol-2)-2,5 difeniltetrazolio. Todos los aislamientos y las cepas de referencia BCG y AN5 se inhibieron con valores CIM de los de H37Rv con buena concordancia entre los resultados obtenidos con ambas técnicas. Los hallazgos permiten sugerir que podrían ser una importante ayuda terapéutica en los lobos marinos con diagnóstico de tuberculosis y evaluar el posible papel sanitario en la prevención y transmisión de la tuberculosis de los animales a los humanos y el trabajo en conjunto

A cor da morte: causas de óbito segundo características de raça no Estado de São Paulo, 1999 a 2001

OBJECTIVE: Assuming that ethnicity might be a basis for social differentiation and that such differences might represent vulnerability to sickness, this study attempts to verify whether race or ethnic origin have an effect on mortality patterns. METHODS: The Sao Paulo State death register was examined from 1999 to 2001 in a contingence table of causes according to the 10th ICD and race or skin-color categories (White, Black, Mulatto and others). Chi-square test was used to check the association between skin-color and cause of death; residual analysis was used to elicit statistically significant excessive occurrences when each category of cause of death and skin color was combined; and correspondence analysis was used to examine overall relations among all categories considered. RESULTS: A total of 647,321 valid death registers were analyzed, among which 77.7% were of Whites, 5.4% of Blacks, 14.3% of Mulattoes and 2.6% of others. A significant association between skin color or race and cause of death was found. It may be observed that, although Blacks and Mulattoes present a similar death profile, on the contrary of Whites and others, which could be aggregated into a single category, the former appear in distinct positions on the multidimensional map presented. Except for mal defined causes, which characterize only the deaths of Blacks, the other causes of death within this group are common to both Blacks and Mulattoes, varying however, in intensity and as to the order in which they appear death. CONCLUSIONS: Analysis of mortality according to race or color revealed that death has a color. There is a White death, which has, among its causes, sicknesses, which, although variable, are nothing more than sicknesses. There's a Black death, which is not caused by sicknesses but by external causes, complications in labor and delivery, mental disorders and ill- defined causes.OBJETIVO: Sob a premissa de que há diferenças sociais segundo a etnia e que essas diferenças se constituem vulnerabilidade para doença, realizou-se estudo para averiguar se a raça/cor condiciona padrões característicos de óbito. MÉTODOS: Pelos registros de óbitos do Estado de São Paulo dos anos de 1999 a 2001, analisou-se a mortalidade proporcional por causa básica, segundo os capítulos da CID-10, entre as categorias de raça ou cor: branca, preta, parda e outras. A tabela de contingência permitiu, além do teste de chi2, a análise de resíduo, que aponta o excesso de óbitos estatisticamente significante, em cada categoria de causa básica e cor. Usou-se a análise de correspondência para a representação gráfica das relações multidimensionais das distâncias chi2 entre as categorias das variáveis estudadas. RESULTADOS: Foram analisados 647.321 registros válidos, sendo 77,7% de brancos, 5,4% de pretos, 14,3% de pardos e 2,6% de outros. Foi encontrada associação significante entre causas de óbito e raça/cor. Observou-se no mapa multidimensional apresentado que pretos e pardos aparecem distantes, ainda que apresentem um perfil de óbito semelhante, ao contrário de brancos e outros que poderiam ser agrupados numa única categoria. À parte as causas mal definidas que caracterizam apenas os óbitos de pretos, as outras causas de óbito desse grupo são comuns a pretos e pardos, variando, no entanto, em ordem de relação e intensidade. CONCLUSÕES: Foi encontrado na análise da mortalidade segundo a raça/cor, que a morte tem cor. Há uma morte branca que tem como causa as doenças, as quais, embora de diferentes tipos, não são mais que doenças. Há uma morte negra que não tem causa em doenças: são as causas externas, complicações da gravidez e parto, os transtornos mentais e as causas mal definidas

Corpos docentes empreendem conjuntamente ou “o corpo ainda é pouco” para tanto?

The aim of the paper is to investigate teachers' perceptions of an undergraduate course at an university in Rio de Janeiro on the possible existence of a joint enterprise. This particular course was chosen because it was highly evaluated in terms of infrastructure, teaching staff and pedagogical organization by the educational authorities in Brazil, and had good results in learning standardized tests at ENADE (Exame Nacional de Desempenho). The first part of the paper presents the contribution of authors working with communities of practice and joint enterprises. The second session describes the methodology employed. The concluding session shows the analysis and the categories that contribute to affirm the existence of the joint enterprise, like knowledge dissemination and academic update. This study expects to contribute to future researchers to confirm existence of communities of practice among teachers.Este artigo teve como objetivo investigar se existe um empreendimento conjunto no seio do corpo docente do curso de Serviço Social da Universidade Alfa que justificasse os seus bons resultados em avaliações padronizadas. Esse curso foi escolhido como amostra em virtude de ter sido avaliado com grau máximo pelos avaliadores ad hoc do Instituto Nacional de Estudos e Pesquisas (INEP) em 2008, com nota 5 nos quesitos infraestrutura, corpo docente e organização didático-pedagógica, bem como ter sido avaliado acima da média no Exame Nacional de Desempenho de Estudantes (ENADE), com nota 4 e Indicador de Diferença dentre os Desempenhos Observado e Esperado (IDD) 3. A primeira parte deste texto apresenta a contribuição de autores que trabalham com comunidades de prática e, consequentemente, empreendimento conjunto. Em seguida, demonstra-se a metodologia empregada neste estudo de caso, com aplicação de entrevistas semiestruturadas. Finalmente, analisam-se as categorias que contribuíram para a confirmação da existência do empreendimento conjunto, como o ato de disseminar conhecimentos e de atualizar-se academicamente de forma constante. Este estudo abre agenda para futuras pesquisas que confirmem a existência de comunidades de prática entre docentes

Estimativa de impacto da amamentação sobre a mortalidade infantil

OBJECTIVE: Infant mortality in the state of São Paulo has decreased in the last years and it seems to be leveling off at a limit beyond which further reductions are challenging. Early neonatal causes account for 50% of these deaths and the remaining are mostly due to pneumonia and diarrhea. This study is to assess the impact of breastfeeding over death reduction. METHODS: Fourteen municipalities of greater São Paulo were studied. Data on breastfeeding was collected through surveys conducted on national immunization campaign days and mortality data was taken from 1999 and 2000 official records. Drawing from literature parameters on risk for death from respiratory infection and diarrhea in non-breastfed infants, fractions of mortality preventable by breastfeeding were calculated. These figures applied to the number of recorded deaths allowed assessing the impact of breastfeeding over mortality for each municipality. RESULTS: Fractions of respiratory infection mortality preventable by breastfeeding varied according to locality and age group between 33% and 72%. As to diarrhea, variation was between 35% and 86%. The impact of breastfeeding over infant mortality was an average reduction of 9.3% with values raging from 3.6% to 13%, depending on the locality considered. CONCLUSIONS: Breastfeeding in the first year of life might be the most feasible strategy to further reduce the current levels of infant mortality in the state of São Paulo.OBJETIVO: A mortalidade infantil no Estado de São Paulo tem mostrado uma redução progressiva nos últimos anos. Atualmente, atinge níveis para além dos quais uma maior redução parece desafiadora. Causas neonatais precoces correspondem a 50% desses óbitos. Entre os óbitos não neonatais precoces, destacam-se a pneumonia e a diarréia como as principais causas. O objetivo da pesquisa é estudar o impacto da amamentação na redução dos óbitos. MÉTODOS: Foram estudados 14 municípios da Grande São Paulo, onde coletaram-se informações relativas à amamentação por entrevistas, em uma amostra por conglomerados em dias nacionais de vacinação (Projeto Amamentação e Municípios). Também foram consultadas informações sobre mortalidade infantil, recolhidas de fontes oficiais, dos anos de 1999 e 2000. Com base em parâmetros da literatura sobre o risco de óbito por infecção respiratória e diarréia para crianças não amamentadas, calculou-se a fração de mortalidade evitável por cada doença. Os valores, aplicados ao número de óbitos registrados em cada município, permitiram o cálculo do impacto da amamentação sobre o Coeficiente de Mortalidade Infantil (CMI). RESULTADOS: A fração de mortalidade evitável por infecção respiratória variou, segundo o município e a faixa etária, entre 33% e 72%. Para diarréia, a variação ficou entre 35% e 86%. A estimativa média de impacto foi de 9,3% no CMI, com variações, segundo o município, entre 3,6% e 13%. CONCLUSÕES: A amamentação no primeiro ano de vida pode ser a estratégia mais exeqüível de redução da mortalidade pós-neonatal para além dos níveis já alcançados em municípios do Estado de São Paulo

Late entry into HIV care: lessons from Brazil, 2003 to 2006

Background: To ascertain the population rates and proportion of late entry into HIV care, as well as to determine whether such late entry correlates with individual and contextual factors. Methods: Data for the 2003-2006 period in Brazil were obtained from public health records. A case of late entry into HIV care was defined as one in which HIV infection was diagnosed at death, one in which HIV infection was diagnosed after the condition of the patient had already been aggravated by AIDS-related diseases, or one in which the CD4(+) T-cell count was &lt;= 200 cells/mm(3) at the time of diagnosis. We also considered extended and stricter sets of criteria (in which the final criterion was &lt;= 350 cells/mm(3) and &lt;= 100 cells/mm(3), respectively). The estimated risk ratio was used in assessing the effects of correlates, and the population rates (per 100,000 population) were calculated on an annual basis. Results: Records of 115,369 HIV-infected adults were retrieved, and 43.6% (50,358) met the standard criteria for late entry into care. Diagnosis at death accounted for 29% (14,457) of these cases. Late entry into HIV care (standard criterion) was associated with certain individual factors (sex, age, and transmission category) and contextual factors (region with less economic development/increasing incidence of AIDS, lower local HIV testing rate, and smaller municipal population). Use of the extended criteria increased the proportion of late entry by 34% but did not substantially alter the correlations analyzed. The overall population rate of late entry was 9.9/100,000 population, specific rates being highest for individuals in the 30-59 year age bracket, for men, and for individuals living in regions with greater economic development/higher HIV testing rates, collectively accounting for more than half of the cases observed. Conclusions: Although the high proportion of late entry might contribute to spreading the AIDS epidemic in less developed regions, most cases occurred in large cities, with broader availability of HIV testing, and in economically developed regions.Brazilian Ministry of HealthBrasilien - Deutsche Gesellschaft fur Technische Zusammenarbeit (GTZ Brazil, German Society for Technical Cooperation in Brazil)Fundacao de Amparo a Pesquisa do Estado de Sao Paulo (FAPESP, Sao Paulo Research Foundation

EVALUACIÓN DE DIVERSIDAD ARBÓREA PARA SELECCIÓN DE ESPECIES SUCEDÁNEAS DE REFORESTACIÓN SUB-CUENCA DEL CARRIZAL

La investigación tuvo como objetivo la evaluación de la diversidad arbórea en el periodo 2011-2016 en la zona alta de la sub-cuenca del Carrizal- Manabí- Ecuador. Una vez identificadas las especies arbóreas se estableció sus atributos como especies sucedáneas considerando los criterios valor ecológico y estratégico para la conservación, elemento cultural o desarrollo de los habitantes y factor de riesgo asociado al taxón de las especies arbóreas identificadas. Para medir la diversidad arbórea se aplicaron transectos, muestreos, claves taxonómicas, que permitieron identificar género, especie y familia, fortalecidos con el conocimiento de investigadores, especialistas y herbarios y fortalecido con la experiencia de los habitantes de esta sub-cuenca, para evaluar la diversidad arbórea se utilizó los índices de biodiversidad Shannon-Weaver, Simpson y el de Equidad de Pielou. Se encontraron un total de 1258 individuos representados en 23 familias arbóreas, 38 géneros y 39 especies. El tipo de especie sucedánea seleccionada fue la “clave” Los atributos enlistados fueron (valor de uso, conservación de otras especies y pérdidas de especies en el periodo de estudio). Se seleccionó como especies arbóreas claves a cuatro especies consideradas de prioridad alta: Castilla elástica, Tabebuia crysantha, Cedrela fissilis y Tabebuia chrysotricha, dos son consideradas de baja prioridad Trema michranta y Baccharis salicifolia, y 33 de las especies identificadas son de prioridad media.PALABRAS CLAVE: Diversidad arbórea; valor de uso; valor ecológico, extinción; microcuenca del río Carrizal.EVALUATION OF ARBOREAL DIVERSITY FOR THE SELECTION OF SUB-BASIN OF THE CARRIZAL SUB-BASIN REFORESTATION SPECIESABSTRACTThe research highlights the attributes of the substitute arboreal species, considering the ecological and strategic value for the conservation of tree species in the high areas of the sub-basin of the Carrizal-Manabí-Ecuador. Its objective was the evaluation of tree diversity, period 2011-2016. To measure its diversity transects, samplings, taxonomic keys were applied, which allowed to identify gender, species and family, with the knowledge of researchers, specialists and herbaria. To assess the site with the greatest diversity of trees, biodiversity indices and equity index were applied using the Shannon-Weaver, Simpson and Equidad de Pielou indices. Obtaining the results of surrogate species was based on the characteristics of the type of "key" surrogate species. A total of 1258 individuals were found represented in 23 families, 38 genera and 39 species. With regard to the selection of substitute species of arboreal biodiversity, it promotes the conservation of ecosystems and specific habitats of other species, importance as an emblematic species, which is endangered (P) of extinction and is phylogenetically unique, or endemic. Key tree species Tabebuia chrysotricha, Tababuia crysantha, Elastic Castilla, Cedrela Fissili were selected as having high attributes in relation to use value, ecological value and conservation, two are considered of low priority Trema michranta and Baccharis salicifolia, and 33 of the species identified are of medium priority.KEYWORDS: Arboreal diversity; use value; ecological value; extinction; micro-basin of the Carrizal River

Adaptations to a semiaquatic lifestyle in the external ear of southern pinnipeds (Otariidae and Phocidae, Carnivora): Morphological evidences

Pinnipeds are semiaquatic carnivorans that spend most of their lives in water and use coastal terrestrial, or ice pack, environments to breed, molt and rest. Certain characteristics of the ear have been linked to ecological aspects. In our contribution we focus on the study of the macroscopic and microscopic morphology of the external ear (with the exception of the osseous outer ear canal) of six species of Southern pinnipeds. In order to recognize the different components of tissues, sections were stained following several routine protocols. In addition, double-staining and enzymatic clearing (Alcian blue-alizarin red) was performed to assess the arrangement of skeletal elements in the OEC. The basic structure of the pinna in the southern otariids studied match those previously analyzed for Northern Hemisphere species. The cartilage macro anatomy of the OEC of Mirounga leonina and Arctocephallus gazella is different from that of the Northern Hemisphere species, with only one plate of cartilage, but markedly different between them. The histology of the otariids OEC is homogeneous along the entire extension, but phocids has three different regions (distal, middle, and proximal). The cartilage histology of most phocids is also different from that of analyzed otariids, with an elastic cartilage that resembles a myxoid-like tissue, but is not present in M. leonina, were the tissue around the OEC is very rich in adipocytes. The southern elephant seal M. leonina OEC has a combination of features similar to both the rest of the phocids and to the otariids. An auditory organ that is functional both over and under water could be essential for social behavior in these species.Fil: Loza, Cleopatra Mara. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional de la Plata. Facultad de Cs.naturales y Museo. Laboratorio de Morfologia Evolutiva y Desarrollo.; Argentina. Universidad Nacional de La Plata. Facultad de Ciencias Naturales y Museo. División Paleontología Vertebrados; ArgentinaFil: Krmpotic, Cecilia Mariana. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional de La Plata. Facultad de Ciencias Naturales y Museo. División Paleontología Vertebrados; Argentina. Universidad Nacional de la Plata. Facultad de Cs.naturales y Museo. Laboratorio de Morfologia Evolutiva y Desarrollo.; ArgentinaFil: Galliari, Fernando Carlos. Universidad Nacional de La Plata. Facultad de Ciencias Naturales y Museo. División Paleontología Vertebrados; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional de la Plata. Facultad de Cs.naturales y Museo. Laboratorio de Morfologia Evolutiva y Desarrollo.; ArgentinaFil: Andrés Laube, Pedro F.. Universidad Nacional de La Plata. Facultad de Ciencias Veterinarias; ArgentinaFil: Negrete, Javier. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Ministerio de Relaciones Exteriores, Comercio Interno y Culto. Dirección Nacional del Antártico. Instituto Antártico Argentino; ArgentinaFil: Scarano, Alejo Carlos. Universidad Nacional de La Plata. Facultad de Ciencias Naturales y Museo. División Paleontología Vertebrados; Argentina. Universidad Nacional de la Plata. Facultad de Cs.naturales y Museo. Laboratorio de Morfologia Evolutiva y Desarrollo.; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional de Avellaneda; ArgentinaFil: Loureiro, Julio. No especifíca;Fil: Carlini, Alfredo Armando. Universidad Nacional de La Plata. Facultad de Ciencias Naturales y Museo. División Paleontología Vertebrados; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Universidad Nacional de la Plata. Facultad de Cs.naturales y Museo. Laboratorio de Morfologia Evolutiva y Desarrollo.; ArgentinaFil: Barbeito, Claudio Gustavo. Universidad Nacional de La Plata; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentin

Evidence of Helicobacter sp. in dental plaque of captive dolphins (Tursiops gephyreus)

Gastrointestinal lesions have been extensively reported in wild and captive marine mammals. However, their etiology remains unclear. In humans and other animals, chronic gastritis and peptic ulcers have been associated with Helicobacter sp. Therefore, the aim of our study was to investigate the presence of Helicobacter sp. in the gastric juice, dental plaque, and saliva of marine mammals living in a controlled environment. Five dolphins (Tursiops gephyreus), one killer whale (Orcinus orca), one false killer whale (Pseudorca crassidens), three sea lions (Otaria flavescens), two elephant seals (Mirounga leonina), and two fur seals (Arctocephalus australis) were studied. Saliva, dental plaque, and gastric juice samples were examined for Helicobacter sp. using polymerase chain reaction. None of the gastric juice or saliva samples were positive for Helicobacter sp. However, Helicobacter sp. DNA was detected in dental plaque from two dolphins, suggesting the oral cavity might be a reservoir of this bacterium.Fil: Goldman, Cinthia Gabriela. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay; Argentina. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica; ArgentinaFil: Loureiro, Julio D.. Fundación Mundo Marino; ArgentinaFil: Quse, Viviana. Fundación Mundo Marino; ArgentinaFil: Corach, Daniel. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay; Argentina. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica; ArgentinaFil: Calderon, Enrique. Fundación Mundo Marino; ArgentinaFil: Caro, Ricardo A.. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica; ArgentinaFil: Boccio, José. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica; ArgentinaFil: Heredia, Sergio Rodríguez. Fundación Mundo Marino; ArgentinaFil: Di Carlo, Maria Beatriz. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica; ArgentinaFil: Zubillaga, Marcela Beatriz. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Houssay; Argentina. Universidad de Buenos Aires. Facultad de Farmacia y Bioquímica; Argentin

Effect of dental bleaching on pulp oxygen saturation in maxillary central incisors - a randomized clinical trial

Objective: To assess pulp oxygen saturation levels (SaO2) in maxillary central incisors after dental bleaching. Materials and Methods: 80 participants (160 teeth) were randomly allocated to four groups: G1 In-office bleaching with two applications of 35% hydrogen peroxide (HP) (20 minutes), followed by at-home bleaching with 10% carbamide peroxide (CP) (2 hours/day for 16 days); G2 - Same protocol as G1, plus desensitizing toothpaste; G3 - Inoffice bleaching with 35% HP and one application of placebo gel (20 minutes), followed by at-home bleaching with 10% CP (2 hours/day for 16 days); and G4 - Same protocol as G3, plus desensitizing toothpaste. Pulp SaO2 levels were measured before (T0) and immediately after (T1) in-office bleaching; on the 5th (T2), 8th (T3), 12th (T4), and 16th days of at-home bleaching (T5); and on the 7th (T6) and 30th (T7) days. Mean (SD) pulp SaO2 levels were compared within groups by generalized estimating equations (GEE) and Student’s t-test (P&lt;0.05). Results: Mean pulp SaO2 at T0 was 84.29% in G1, 84.38% in G2, 84.79% in G3, and 85.83% in G4. At T1, these values decreased to 81.96%, 82.06%, 82.19%, and 81.15% in G1, G2, G3, and G4 respectively, with significant difference in G4 (P&lt;0.05). During home bleaching, pulp SaO2 levels varied in all groups, with 86.55%, 86.60%, 85.71%, and 87.15% means at T7 for G1, G2, G3, and G4, respectively; G2 presented significant difference (P&lt;0.05). Conclusions: Pulp SaO2 level in maxillary central incisors was similar at baseline, reducing immediately after in-office bleaching, regardless of using desensitizing toothpaste and increasing at 30 days after dental bleaching