When art education meets environmental issues: the interconnectedness of art and science

In recent years, we have come to understand that the environmental crisis is no longer what we see in books or screens but it is what we are facing now. Along with the public\u27s increasing interest in the environment post-COVID, this thesis explores the role of art in enhancing awareness of critical environmental issues. Through a literature review, the author examines theoretical concepts at the core of the history of art and science in search of ideas about the interconnectedness of science and art. The review explores why an interdisciplinary approach to education is vital to learning about environmental issues and the unique and non-subsidiary role art can play in understanding science. The author reviews current pedagogical models in settings such as schools, galleries, and museums, where there is an integration of art and science. And through an analysis of these models, the author identifies promising practices and areas they argue are in need of greater consideration. In this thesis, the author focuses on various new approaches to environmental issues through art education that move beyond traditional concepts of environmental arts education and emphasizes the role of the media as art teacher. The thesis presents the author\u27s interdisciplinary experiences while in graduate school at the Rhode Island School of Design (RISD), where writing and research are incorporated into art practice as a possible conceptual foundation for integrated teaching and learning pedagogy. The author argues that environmental issues do not exist apart from us but are closely linked to us in various ways. However, they further claim there is still a significant gap in educational contexts between learners’ awareness and a deeper understanding of environmental issues. The author concludes that art education has considerable potential in regard to creativity development and empowerment which they argue can bridge this gap and lead to change

Engaging Ethical Issues Associated with Research and Public Health Interventions During Humanitarian Crises: Review of a Dialogic Workshop

Compte-rendu / ReviewLe 7 novembre 2014, l’atelier intitulé Humanitarian Health Ethics Workshop a été tenu à l’Université McGill, à Montréal. Hébergé conjointement par le Consortium de recherche sur l’équité en santé de Montréal et le Humanitarian Health Ethics Network, l’événement comprenait six présentations et une discussion extensive entre les participants, incluant des chercheurs du Canada, de Haïti, de l’Inde, de la Suisse et des États-Unis. Les participants étaient de diverses disciplines, soit l’anthropologie, la bioéthique, la médecine, l’ergothérapie, la philosophie, la physiothérapie, les sciences politiques, l’administration et la santé publique. L’objectif de l’atelier était de créer un forum de discussion entre experts et praticiens qui s’intéressent à l’éthique dans la prestation de soins de santé, en recherche et dans les interventions de santé publique en cours de crise humanitaire. Ce compte rendu résume les présentations, les thèmes clés qui ont émergé des discussions de la journée et identifie des pistes de recherches futures.On November 7th, 2014 the Humanitarian Health Ethics Workshop was held at McGill University, in Montreal. Co-hosted by the Montreal Health Equity Research Consortium and the Humanitarian Health Ethics Network, the event included six presentations and extensive discussion amongst participants, including researchers from Canada, Haiti, India, Switzerland and the US. Participants had training in disciplines including anthropology, bioethics, medicine, occupational therapy, philosophy, physical therapy, political science, public administration and public health. The objective of the workshop was to create a forum for discussion amongst scholars and practitioners interested in the ethics of healthcare delivery, research and public health interventions during humanitarian crises. This review is a summary of the presentations given, key themes that emerged during the day’s discussions, and avenues for future research that were identified

On Lundh's percolation difussion

A collection of spherical obstacles in the ball in Euclidean space is said to be avoidable for Brownian motion if there is a positive probability that Brownian motion diffusing from some point in the ball will avoid all the obstacles and reach the boundary of the ball. The centres of the spherical obstacles are generated according to a Poisson point process while the radius of an obstacle is a deterministic function depending only on the distance from the obstacle's centre to the centre of the ball. Lundh has given the name percolation diffusion to this process if avoidable configurations are generated with positive probability. An integral condition for percolation diffusion is derived in terms of the intensity of the Poisson point process and the function that determines the radii of the obstacles

Approach to exploring interstellar objects and long-period comets

This paper aims to identify the best approaches for exploring planetary bodies with very long orbital periods, i.e., bodies that approach Earth only once in a lifetime. This includes long-period comets (LPCs), and the newly discovered classes of Manx comets and interstellar objects (ISOs). Long-period comets are high scientific value targets, as indicated in the current Planetary Science Decadal Survey. Interstellar objects open the fascinating possibility to sample exoplanetary systems. Manxes hold the key to resolving long-time questions about the early history of our solar system. Specific strategies need to be implemented in order to approach bodies whose orbital properties are at the same time extreme and unpredictable. As ground-based telescope capabilities are greatly improving, it will soon become possible to detect LPCs more than ten years before they reach perihelion. On the other hand, the non- or weakly active Manx comets and ISOs require reactive exploration strategies. All of these bodies offer many challenges for close proximity observations that can be addressed by the deployment of multi-spacecraft architectures. We describe several concepts that leverage the many advantages offered by distributed sensors, fractionated payload, and various mother-daughter configurations to achieve high impact science within the reach of low-cost missions

Cost effective, experimentally robust differential-expression analysis for human/mammalian, pathogen and dual-species transcriptomics.

As sequencing read length has increased, researchers have quickly adopted longer reads for their experiments. Here, we examine 14 pathogen or host-pathogen differential gene expression data sets to assess whether using longer reads is warranted. A variety of data sets was used to assess what genomic attributes might affect the outcome of differential gene expression analysis including: gene density, operons, gene length, number of introns/exons and intron length. No genome attribute was found to influence the data in principal components analysis, hierarchical clustering with bootstrap support, or regression analyses of pairwise comparisons that were undertaken on the same reads, looking at all combinations of paired and unpaired reads trimmed to 36, 54, 72 and 101 bp. Read pairing had the greatest effect when there was little variation in the samples from different conditions or in their replicates (e.g. little differential gene expression). But overall, 54 and 72 bp reads were typically most similar. Given differences in costs and mapping percentages, we recommend 54 bp reads for organisms with no or few introns and 72 bp reads for all others. In a third of the data sets, read pairing had absolutely no effect, despite paired reads having twice as much data. Therefore, single-end reads seem robust for differential-expression analyses, but in eukaryotes paired-end reads are likely desired to analyse splice variants and should be preferred for data sets that are acquired with the intent to be community resources that might be used in secondary data analyses

The Effect of High-Impact Exercise on Stress Urinary Incontinence in Physically Active Women

Stress urinary incontinence (SUI) is a condition in which increased abdominal pressure with coughing, laughing, sneezing, or exercise can cause unintentional leakage of urine in the female population. CrossFit and other high impact aerobic exercises, are popular forms of exercise amongst women all age groups. The purpose of this study was to examine specific high impact exercises that can affect SUI in women

Insomnia as an Independent Predictor of Incident Cardiovascular Disease in HIV: Data from the Veterans Aging Cohort Study

Background: Insomnia is associated with increased cardiovascular disease (CVD) risk in the general population and is highly prevalent in people with HIV. The CVD risk conferred by insomnia in the HIV population is unknown. Methods: Using the Veterans Aging Cohort Study-Survey Cohort, insomnia symptoms were measured and dummy coded with the item, “Difficulty falling or staying asleep?” (5-point scale from no difficulty to bothers a lot). Incident CVD event ICD-9 codes (acute myocardial infarction, stroke, or coronary artery revascularization) were identified with VA and Medicare administrative data and VA fee-for-service data. Those with baseline CVD were excluded. Results: HIV-infected (N=3,108) veterans had a median follow-up time of 10.8 years, during which 267 CVD events occurred. Compared to HIV-infected veterans with no difficulty falling or staying asleep, HIV-infected veterans bothered a lot by insomnia symptoms had an increased risk of incident CVD after adjusting for demographics (HR=1.64, 95%CI=1.16-2.31, p=.005), CVD risk factors (HR=1.62, 95%CI=1.14-2.30, p=.007), additional potential confounders (hepatitis C infection, renal disease, anemia, alcohol use, cocaine use; HR=1.70, 95%CI=1.19-2.43, p=.003), and HIV-specific factors (HIV-1 RNA, CD4+ T-cell count, ART; HR=1.66, 95%CI=1.16-2.37, p=.005). Additional adjustment for non-benzodiazepine sleep medication (HR=1.62, 95%CI=1.13-2.32, p=.009) did not attenuate the association; however, it fell short of significance at p < .01 after adjustment for depressive symptoms (HR=1.51, 95%CI=0.98-2.32, p=.060) or antidepressant medication (HR=1.51, 95%CI=1.04-2.19, p=.031). Conclusion: Highly bothersome insomnia symptoms were significantly associated with incident CVD in HIV-infected veterans, suggesting that insomnia may be a novel, modifiable risk factor for CVD in HIV

Diversifying selection and functional analysis of interleukin-4 suggests antagonism-driven evolution at receptor-binding interfaces

<p>Abstract</p> <p>Background</p> <p>Interleukin-4 (IL4) is a secreted immunoregulatory cytokine critically involved in host protection from parasitic helminths <abbrgrp><abbr bid="B1">1</abbr></abbrgrp>. Reasoning that helminths may have evolved mechanisms to antagonize IL4 to maximize their dispersal, we explored mammalian IL4 evolution.</p> <p>Results</p> <p>This analysis revealed evidence of diversifying selection at 15 residues, clustered in epitopes responsible for IL4 binding to its Type I and Type II receptors. Such a striking signature of selective pressure suggested either recurrent episodes of pathogen antagonism or ligand/receptor co-evolution. To test the latter possibility, we performed detailed functional analysis of IL4 allotypes expressed by <it>Mus musculus musculus </it>and <it>Mus musculus castaneus</it>, which happen to differ at 5 residues (including three at positively selected sites) in and adjacent to the site 1 epitope that binds the IL4Rα subunit shared by the Type I and Type II IL4 receptors. We show that this intra-species variation affects the ability of IL4 neither to bind IL4 receptor alpha (IL4Rα) nor to signal biological responses through its Type I receptor.</p> <p>Conclusions</p> <p>Our results -- reminiscent of clustered positively selected sites revealing functionally important residues at host-virus interaction interfaces -- are consistent with IL4 having evolved to avoid recurrent pathogen antagonism, while maintaining the capacity to bind and signal through its cognate receptor. This work exposes what may be a general feature of evolutionary conflicts fought by pathogen antagonists at host protein-protein interaction interfaces involved in immune signaling: the emergence of receptor-binding ligand epitopes capable of buffering amino acid variation.</p