The glucose reducing effects of a physical regimen combining putu sila and tai chi in individuals with type 2 diabetes mellitus in the public health center of bima

Diabetes mellitus hyperglycemia is a chronic disease characterized by the absence of insulin or a relative decrease in cell insensitivity to insulin that requires continuous treatment and ongoing self-management to prevent acute complications and reduce the risk of chronic complications. Type 2 diabetes mellitus is particularly by physical activity. This study aims to understand the difference between two exercise regimens on blood glucose levels reduction in patients with type 2 diabetes mellitus. This was a quasi-experimental study with a pre-test post-test control group design. 60 respondents were selected via random sampling and divided evenly into two groups of 30 individuals: 1) the treatment group; and 2) the control group. A Wilcoxon test performed on the treatment group yielded P-value = 0,005 < ? = 0,05 and a Wilcoxon test performed on the control group yielded P-value = 0,046 < ? = 0,05. The conclusion that can be drawn from this study is that physical activity has an effect of reducing blood glucose levels in patients with type 2 diabetes mellitus, and, when comparing the differences in blood glucose level reduction, a combined regimen of putu sila and Tai Chi is more effective than Tai Chi alone

Automatic translation of non-repetitive OpenMP to MPI

Cluster platforms with distributed-memory architectures are becoming increasingly available low-cost solutions for high performance computing. Delivering a productive programming environment that hides the complexity of clusters and allows writing efficient programs is urgently needed. Despite multiple efforts to provide shared memory abstraction, message-passing (MPI) is still the state-of-the-art programming model for distributed-memory architectures. ^ Writing efficient MPI programs is challenging. In contrast, OpenMP is a shared-memory programming model that is known for its programming productivity. Researchers introduced automatic source-to-source translation schemes from OpenMP to MPI so that programmers can use OpenMP while targeting clusters. Those schemes limited their focus on OpenMP programs with repetitive communication patterns (where the analysis of communication can be simplified). This dissertation reduces this limitation and presents a novel OpenMP-to-MPI translation scheme that covers OpenMP programs with both repetitive and non-repetitive communication patterns. We target laboratory-size clusters of ten to hundred nodes (commonly found in research laboratories and small enterprises). ^ With our translation scheme, six non-repetitive and four repetitive OpenMP benchmarks have been efficiently scaled to a cluster of 64 cores. By contrast, the state-of-the-art translator scaled only the four repetitive benchmarks. In addition, our translation scheme was shown to outperform or perform as well as the state-of-the-art translator. We also compare the translation scheme with available hand-coded MPI and Unified Parallel C (UPC) programs

The Application Model of Political Ethics on the Government Bureaucracy during Covid-19 Pandemicin Ternate City

This research has two objectives; Namely, first, it aims to examine more deeply the model of political ethics and actor bureaucracy and second to examine the application of ethical models of political actors and the Ternate bureaucracy. The research method used is qualitative. The data analysis technique uses content analysis by examining the data collected from semi-structured interviews and relevant documents and articles. The research results reveal that the Ternate City Government always appreciates the moral values that live in the Ternate community. Make it a guideline in issuing policies. As the center of government of Ternate City, Ternate is an inseparable part of the history of the Sultanate of Ternate, which still upholds cultural values in carrying out every social, religious, and political activity. This is symbolized by the noble values of the Ternate people, namely Kie se Gam nagogugumatitirara (six basic traditions that are firmly held) and Jou se NgofaNgare (what is in you is with me and what is in me is also in you). In various policies, especially during the Covid-19 pandemic, the City Government has put forward ethical values rooted in the Jou Se NgofaNgare philosophy, namely understanding what is in me and vice versa, what is inside of me. Also yours. The overall ethical values it contains are limited to the relationship between God and humans and manifest in political life and state administration. Furthermore, it was revealed that the Ternate City Government views that the relationship with the community is a complementary and necessary unit. Therefore, in its policy, the City Government of Ternate is very egalitarian and accommodating to people of different ethnicities and religions. This research shows that the Ternate City Government is required to obey the constitutional rules and accommodate and respect the cultural values that live in the community. The expected implication is that the constitutional constitution and cultural values in Ternate City, which contain ethical values, are applied by every political actor and a government bureaucracy to be fully aware of their people's duties and responsibilities

The Tailored Production of Small Diameter Fibres and Their Applications in Wound Healing

Thinner fibres benefit from a high surface area to volume ratio which is valuable in many biomedical applications ranging from tissue engineering to drug delivery and wound healing. Fibre forming technologies such as electrospinning and pressurised gyration rely on the careful manipulation of solution properties as well as working parameters to obtain the most optimal fibre morphology for their intended applications. In deeply understanding how these fibre manufacturing technologies work, there can be highly optimised and tailored production of polymeric biomaterials. Natural substances represent a class of materials that fail to be forgotten for use in health-related applications. Honey and cinnamon have gained significant interest not only for their physical and chemical properties but also for their antibacterial activity. Manuka Honey UMF 20+ was examined for its antibacterial properties against Escherichia coli and Staphylococcus epidermidis using flow cytometry where the active agent is thought to be the high methylglyoxal content. The inhibitory effect of manuka honey on bacterial growth was evident at concentrations ranging from 10 to 30 v/v%, where higher concentrations benefited from additional honey loading. The incorporation of Manuka honey as an antibacterial agent was explored as a potential route for manufacturing wound dressing components. Using pressurised gyration, scaffolds of sub-micrometre fibres were formed from 10, 20 and 30 v/v% Manuka honey which were incorporated into the polycaprolactone polymer solutions. The composite fibres were analysed for their morphology and topography using scanning electron microscopy. The average fibre diameter of the Manuka honey-polycaprolactone scaffolds was found to be in the range of 437 to 815 nm. The antibacterial activity of the most potent 30 v/v% scaffolds was studied against S. epidermidis. The scaffolds showed strong antibacterial activity with a bacterial reduction rate of over 90%. The results here show that honey composite fibres can be considered a natural therapeutic agent for wound healing applications. Fibrous bandage-like constructs made with incorporated cinnamon extract have been previously shown to have potent antifungal abilities which surpass even the raw material itself. The question remains as to whether these constructs are useful in the prevention of bacterial infections and what the antimicrobial effect means in terms of toxicity to native physiological cells. In this work cinnamon-extracted fibres are tested against Staphylococcus epidermidis to assess their antibacterial capacity; it was found that the fibres were able to successfully kill the bacteria. The constructs were also tested under indirect MTT cytotoxicity tests involving the L929 mouse fibroblast cell line, where they showed no variation from the control groups in terms of toxicity. Additionally, cell viability imaging showed no significant toxicity issues with the fibres, even at their tested highest concentration. Here I present a viable method to produce wound healing products made from non-toxic and abundant naturally occurring materials such as cinnamon. Two fibre forming techniques, pressurised gyration and electrospinning have been combined to create a manufacturing process where advanced wound healing bandages can be created. This new hybrid process leverages the rapid production rate of pressurised gyration to create the bulk portion of the bandages and exploits the precise nature of electrospinning to directly print a bioactive fibrous patch onto the active site of the bandages. Polycaprolactone bandages have thus been created which have a bioactive patch consisting of collagen and chitosan with a poly(ethylene oxide) support. The patches have an average fibre diameter of 173 ± 27 nm and closely resemble the extracellular matrix in its structure, together with the active collagen and chitosan, this will be crucial in their ability to facilitate advanced wound healing. Additionally, synthetic materials such as antimicrobial nanoparticles can be added to the patches which demonstrate that the manufacturing technique is not limited to only using natural materials. Patches with these nanoparticles had an average fibre diameter of 142 ± 31 nm and demonstrated that very uniform and thin fibres could be created with these materials. The process has a great degree of automation and has potential for industrial scalability. The advancement of manufacturing processes needs to be supported by the discovery of novel materials and novel combinations of existing materials. Graphene possesses many properties that have predominately been investigated for commercial applications. For the first time, porous graphene (PG) has been incorporated into polymer matrices produced by a high-output manufacturing process. Graphene and its other derivates such as graphene oxide have been shown to provide an antibacterial surface that can mechanically kill pathogens that encounter it. For this reason, graphene nanopores presents itself as a viable additive for wound healing materials. This overarching work focuses on the production of small diameter fibres via multiple techniques to achieve the most control over the final fibre morphology for uses in advanced wound healing materials

The Cardio-Protective Effects of Substance P in Both Ischemia/Reperfusion and and Short-Term Hypoxia Rat Models

Substance P, a member of the tachykinin family, is found primarily in sensory nerves. In the heart, substance P-containing nerve fibers surround coronary vessels, making them ideally positioned to sense changes in coronary pressure and/or flow. Recent studies have identified substance P as being protective acutely following ischemia-reperfusion due to its ability to induce coronary blood vessel vasodilation. In addition, studies conducted on non-cardiac tissue have reported substance P to be protective against cell death through a mechanism involving activation of anti-apoptotic AKT pathway. However, the possibility of substance P being similarly cardioprotective has not been reported. Accordingly, the purpose of this study was to test the hypothesis that substance P attenuates cardiomyocyte cell death following ischemia/reperfusion. A rat isolated heart preparation was used to study the effect of substance P following global ischemia/reperfusion, while a rat left ventricular tissue slice culture preparation was used to study the effect of substance P in ischemia without reperfusion. Coronary flow was significantly increased during reperfusion and LDH release was less in substance P pretreated ischemia/reperfusion hearts compared with no-treatment ischemia/reperfusion hearts. In the cultured slice preparation, substance P was shown to be effective in decreasing hypoxic-induced LDH release, apoptosis (TUNEL), and necrosis (PAS), as well as increasing AKT activation (phosphorylation) in a dose dependent manner. Inhibition of the substance P receptor (NK1) or p-AKT resulted in an increased release of LDH, apoptosis, and necrosis in hypoxic slices incubated with substance P, thus abolishing the protective effect of substance P. These findings indicate that, in addition to its coronary vasodilatory effect, substance P is cardioprotective via a cardiomyocyte antiapoptotic mechanism

Penerapan Evaluasi Ranah Afektif Siswa dalam Pembelajaran Berbasis Kurikulum 2013 di Madrasah Tsanawiyah Negeri 2 Kotamobagu

Abstrak : Penelitian ini bertujuan untuk menganalisis penerapan, problematika, dan solusi  evaluasi ranah afektif siswa pada pembelajaran berbasis kurikulum 2013 di MTs Negeri 2 Kotamobagu. Metodologi penelitian menggunakan pendekatan kualitatif. Teknik pengumpulan data menggunakan observasi, wawancara dan dokumen. Hasil penelitian yaitu: 1)  Implementasi evaluasi ranah afektif di MTs Negeri 2 Kotamobagu secara umum sudah dilaksanakan namun belum maksimal 2) Problematika evaluasi ranah afektif di MTs Negeri 2 Kotamobagu, guru belum memahami dengan baik tentang pengukuran ranah afektif siswa, sehingga penilaian hanya berdasarkan pengamatan di dalam kelas, tanpa ada catatan tentang sikap siswa selama pembelajaran. 3) Solusi terhadap problematika evaluasi ranah afektif siswa di MTs Negeri 2 Kotamobagu berkaitan dengan teknik evaluasi, maka kepala madrasah menginstruksikan kepada guru untuk membuat laporan  evaluasi sikap. Untuk mengatasi permasalahan berkaitan dengan pelanggaran terhadap ranah afektif siswa, maka guru melakukan bimbingan terhadap siswa di MTs Negeri 2 Kotamobagu. Abstract : Research objectives to analyze the application,  problems, and solutions  to evaluation domain affective on learning based Kurikuum 2013 in MTs Negeri 2 Kotamobagu. Using techniques data collection observation, interviews and documents. The results are:  1) The implantation of the evaluation affective domain in MTS Negeri 2 Kotamobagu in generalization have been implementation, but unoptimized.  2) The problems of evaluation affective domain in MTs Negeri 2 Kotamobagu is teachers understand about measuring affective domain studen, that is implementation of assessment base direct observation in the classroom, without have note a students on the learning process. 3) The Solutions of problems to evaluation affective domain students in MTs Negeri 2 Kotamobagu relating to a technique evaluation, so the head madrasah instructed the teachers to make a report evaluation of attitude. To solve the problem pertaining to a violation of domain affective students, the teacher do guidance of students in MTs Negeri 2 Kotamobagu.Kata Kunci : Evaluasi, Ranah Kognitif, Kurikulum 201

Use Techniques of Remote Sensing Images and Geographic Information Systems to Estimate the Area of Random Housing

The use of technology of remote sensing images and science of geographic information systems are interconnected for the purpose of visual interpretation of satellite and aerial images corrected geometrically, which are frequently a scale large fee for the purpose of conducting engineering measurements it can use this modern technology in the squatter area account within the city of Samawa center is fast and accurate outcome helping to assess and study the situation for this type of housing, which spread after 2003, where are these spaces classified on the basis of the density of housing units that are spread in the area exploited for this purpose based "on the intensity scale designed by the researcher and the results show that he can use this method to produce cadastral map is accurate and inexpensive and a short time afterwards spaces untapped showing housing RAM can be made to repeat the process to search different periods of time for the purpose of assessing the problem and to develop appropriate solutions. Keywords: use of technology of remote sensing, geographic information systems, random Housin