Designing an Artifact to Empower Chronic Patients for Monitoring Health During a Pandemic: A COVID-19 Screening App

Chronic diseases have been declared an invisible epidemic by the World Health Organization (WHO, 2005). Over the past fifty years, the prevalence of chronic conditions has increased, leading to the disease burden caused by cancer, cardiovascular diseases, diabetes, and mental and substance use disorders (DOH, 2021). Chronic patients need to reimagine how they will empower themselves to effectively manage and monitor their health and wellbeing in a COVID-19 era when frequent in-person health care visits will no longer be feasible. In this study, we propose the dimensions for the design of a mobile-based application that will aid chronic patients and end-users in self-managing and monitoring their health during the pandemic era. Based on an empirical investigation involving pharmacists and researchers, we designed and developed a prototype capable of empowering chronic patients. This study particularly focuses on how technological interventions can help chronic patients self-manage and monitor their health and well-being related to COVID-19 where the user expectations are met with less attrition rates

Analysis of urban greening scenarios for improving outdoor thermal comfort in neighbourhoods of Lecce (Southern Italy)

This study analyses the interactions and impacts between multiple factors i.e., urban greening, building layout, and meteorological conditions that characterise the urban microclimate and thermal comfort in the urban environment. The focus was on two neighbourhoods of Lecce city (southern Italy) characterised through field campaigns and modelling simulations on a typical hot summer day. Field campaigns were performed to collect greening, building geometry, and microclimate data, which were employed in numerical simulations of several greening scenarios using the Computational Fluid Dynamics-based and microclimate model ENVI-met. Results show that, on a typical summer day, trees may lead to an average daily decrease of air temperature by up to 1.00 °C and an improvement of thermal comfort in terms of Mean Radiant Temperature (MRT) by up to 5.53 °C and Predicted Mean Vote (PMV) by up to 0.53. This decrease is more evident when the urban greening (in terms of green surfaces and trees) is increased by 1266 m2 in the first neighbourhood and 1988 m2 in the second one, with respect to the current scenario, proving that shading effect mainly contributes to improving the urban microclimate during daytime. On the contrary, the trapping effect of heat, stored by the surfaces during the day and released during the evening, induces an increase of the spatially averaged MRT by up to 2 °C during the evenings and a slight deterioration of thermal comfort, but only locally where the concentration of high LAD trees is higher. This study contributes to a better understanding of the ecosystem services provided by greening with regard to microclimate and thermal comfort within an urban environment for several hours of the day. It adds knowledge about the role of green areas in a Mediterranean city, an important hot spot of climate change, and thus it can be a guide for important urban regeneration plans

Costs and benefits of bevacizumab vial sharing for the treatment of retinal diseases

Antiangiogenic therapy has proved to be an important therapeutic tool for many retinal vascular diseases; however, its availability is limited in developing countries. This study sought to describe the bevacizumab vial sharing process and to evaluate the impact of this repackaging system on the costs incurred in a Brazilian public hospital. Method This retrospective study compared the number and costs of intravitreal antiangiogenic injections approved via court order in the first year of the study (2015) to the number and costs of the bevacizumab injections provided through the use of vial sharing in the second year of the study (2016). Vial sharing consists of the traditional process used to repackage bevacizumab; in this case, however, the drug samples used were the residual volume from the preparation of bevacizumab for oncology patients. The hospital adhered to the guidelines established by the Brazilian Health Surveillance Agency (ANVISA). Results In the first year of the study and using medication obtained through court orders, 550 intravitreal injections were performed in the ophthalmology ambulatory care center. Based on local pricing tables, the total cost of the medication was BRL$1,036,056.25 (USD$267,546.58), and the average cost of each application was BRL$1883.74 (USD$486.45). In the second year of the study, 1081 intravitreal applications were performed at the same hospital using doses obtained through bevacizumab vial sharing. The total cost was BRL$21,942.49 (USD$5663.30) and the per-unit cost was BRL$20.30, or USD$5.23 (a savings of 97.88%). Conclusion This study found that bevacizumab vial sharing led to a significant reduction in public health care costs associated with antiangiogenic treatment and increased the availability of the drug to public health care patients. These results can be extrapolated to other types of drugs and health care systems1

Experimental investigation on camera calibration for 3D photogrammetric scanning of micro-features for micrometric resolution

[EN] Recently, it has been demonstrated that photogrammetry can be used for the measurement of small objects with micro-features, with good results and lower cost, compared to other established techniques such as interferometry, conoscopic holography, and 3D microscopy. Calibration is a critical step in photogrammetry and the classical pinhole camera model has been tested for magnifications lower than 2×. At higher magnification levels, because of the reduction of the depth of field (DOF), images can lead to calibration data with low reprojection errors. However, this could lead to bad results in the 3D reconstruction. With the aim of verifying the possibility of applying the camera model to magnifications higher than 2×, experiments have been conducted using reflex cameras with 60 mm macro lens, equipped with the combination of three extension tubes, corresponding to 2.06, 2.23, and 2.4 magnification levels, respectively. Experiments consisted of repeating calibration five times for each configuration and testing each calibration model, measuring two artifacts with different geometrical complexity. The calibration results have shown good repeatability of a subset of the internal calibration parameters. Despite the differences in the calibration reprojection error (RE), the quality of the photogrammetric 3D models retrieved was stable and satisfying. The experiment demonstrated the possibilities of the photogrammetric system presented, equipped to very high magnification levels, to retrieve accurate 3D reconstruction of micro-features with uncertainties of few micrometers, comparable with industry s expensive state-of-the-art technologies.Percoco, G.; Guerra, MG.; Sánchez Salmerón, AJ.; Galantucci, LM. (2017). Experimental investigation on camera calibration for 3D photogrammetric scanning of micro-features for micrometric resolution. 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Morphology and topography of the liver and pancreas of Rhea americana

As emas são aves ratitas nativas do continente sul americano, são consideradas aves primitivas do ponto de vista filogenético que constituem um grupo altamente especializado. Este estudo buscou caracterizar macro e microscopicamente o fígado e pâncreas de emas. O material foi coletado no Centro de Multiplicação de Animais Silvestres (CEMAS), na cidade de Mossoró-RN, Brasil, (Registro IBAMA n° 14.78912). Utilizaram-se 20 animais jovens com idade entre dois e seis meses independente do sexo. Em emas, o fígado se relacionava cranialmente com o ápice do coração, dorsalmente com os pulmões, esôfago e o proventrículo gástrico, caudalmente, com o ventrículo gástrico, o baço, o duodeno e parte do jejuno. Apresentava coloração vermelha escura e possuía apenas dois lobos, sendo o direito ligeiramente menor que o esquerdo. Histologicamente, era revestido por uma cápsula de tecido conjuntivo delgada e cada lóbulo hepático pôde ser identificado pela presença evidente de veias centrais, com muitos sinusoides comunicando-se com elas. O pâncreas, ventralmente, apresentava-se como uma fita fina, formado por um lobo dorsal e um lobo ventral. Longitudinalmente o pâncreas em emas localiza-se no mesentério dorsal desde o fígado até a flexura cranial do duodeno, mantendo-se preso às alças duodenais por ligamentos. Histologicamente, era composto por uma cápsula delgada de tecido conjuntivo denso, com discretos lóbulos separados por tecido conjuntivo capsular, compostos por estruturas tubuloalveolares e ductos. O fígado e pâncreas de emas apresentam padrão morfológico similar ao descrito para aves domésticas.The rhea are ratites birds native of the South American continent, which are considered primitive birds from the standpoint of the phylogenetic group that is highly specialized. This study aimed to characterize gross and microscopically the liver and rhea pancreas. The material was collected in a Wild Animals Multiplication Center, Mossoro-RN, Brazil, (Registration no 14.78912 IBAMA). It was used 20 young animals aged between two and six months independent of sex. In the rhea the liver is related to the cranial apex of the heart, dorsally with the lungs, esophagus and gastric proventriculus, caudally with the gastric ventricle, the spleen, the duodenum and part of the jejunum. It was dark red color and had only two lobes, being the right lobe slightly smaller than the left. Histologically was lined by a thin connective tissue capsule and each lobe liver could be clearly identified by the presence of central veins, with sinusoids communicating with the veins. The pancreas, ventrally, showed a thin tape formed by a dorsal lobe and a ventral lobe. Longitudinally the pancreas in rhea is located in the dorsal mesentery since the liver until the cranial duodenal flexure, remaining connected the duodenal handles by ligaments. Histologically was composed of a thin capsule of dense connective tissue, with discrete lobules separated by capsular connective tissue, composed of tubuloalveolares structures and pipelines. The liver and pancreas of rhea have morphology similar to that described for domestic poultry

Estimation methods of non-additive effects for characteristics of weight and scrotal circumference in crossbred beef cattle

The objective of this study was to investigate, in a population of crossbred cattle, the obtainment of the non-additive genetic effects for the characteristics weight at 205 and 390 days and scrotal circumference, and to evaluate the consideration of these effects in the prediction of breeding values of sires using different estimation methodologies. In method 1, the data were pre-adjusted for the non-additive effects obtained by least squares means method in a model that considered the direct additive, maternal and non-additive fixed genetic effects, the direct and total maternal heterozygosities, and epistasis. In method 2, the non-additive effects were considered covariates in genetic model. Genetic values for adjusted and non-adjusted data were predicted considering additive direct and maternal effects, and for weight at 205 days, also the permanent environmental effect, as random effects in the model. The breeding values of the categories of sires considered for the weight characteristic at 205 days were organized in files, in order to verify alterations in the magnitude of the predictions and ranking of animals in the two methods of correction data for the non-additives effects. The non-additive effects were not similar in magnitude and direction in the two estimation methods used, nor for the characteristics evaluated. Pearson and Spearman correlations between breeding values were higher than 0.94, and the use of different methods does not imply changes in the selection of animals

Efeitos do isolamento social nos índices de violência à mulher: um estudo comparativo durante a pandemia de COVID-19 em Minas Gerais / Effects of social isolation on violence indices of women: a comparative study during the COVID-19 pandemic in Minas Gerais

A pandemia de COVID-19 que se alastrou pelo mundo todo no ano de 2020 criou tempos atípicos e situações delicadas, em que as pessoas tiveram que se recolher em suas casas, na intenção de diminuir o impacto causado pelo vírus SARS-CoV-2. Tendo em vista a violência contra à mulher, uma problemática que assola a população brasileira há décadas - não distante o estado de Minas Gerais - vem apresentado neste estudo em que  foram analisados os índices dos anos de 2018, 2019 e principalmente durante o período de isolamento social no ano de 2020, em que foi percebido uma diminuição no número de casos durante a pandemia, em relação ao mesmo período nos dois anos anteriores. Ainda, diante dessas informações, foram discutidas as possíveis razões que fundamentam esses resultados. Nesse sentido, atribui-se às hipóteses da diminuição das denúncias e, consequentemente, das notificações ou, então, da real diminuição no número de casos, devido à eficácia das campanhas contra a violência à mulher

Estudo sobre a influência da inserção do Massará em argamassas de assentamento de blocos cerâmicos / Study on the influence of insertion of Massará in ceramic blocks laying mortars

O massará é conhecido apenas na região de Teresina-PI. De acordo com Correia Filho (1997), é um material ligante, de pouca consistência, facilmente desagregável (friável), contendo seixos brancos de sílica. Este trabalho tem o objetivo de verificar a influência do massará, enquanto componente das argamassas de assentamento de blocos cerâmicos, que associado ao cimento portland e parcialmente ao agregado miúdo pode vir a formar a argamassa de assentamento. Tendo em vista que a areia utilizada em argamassas na cidade de Teresina é toda advinda dos rios, e o massará é extraído da lavagem do material que dá origem ao seixo encontrado em jazidas. Esse estudo visa à obtenção de um traço de argamassa obtido com a utilização do massará, onde serão feitos ensaios mecânicos e de caracterização do material em laboratório. Diversos traços serão experimentados e em seguida serão moldados corpos de prova e amostras para obtenção dos resultados da resistência e trabalhabilidade dos mesmos. Após a realização dos ensaios, será estudada a possibilidade de usá-lo como componentes das argamassas de assentamento utilizadas em construtoras de Teresina - PI

Maquina Verde - El Arca Solar Decathlon Latin America & Caribbean 2019

The current supply of social housing in Latin American countries is often not adequate for the real needs of the population, generating situations of social conflict and permanent contraposition between the “formal” and the “informal” cities. The Pontificia Universidad Javeriana of Bogotá and the Politecnico di Torino participated together in the Solar Decathlon Latin America and Caribbean 2019 competition with the project Máquina Ver-de - El Arca, a vivienda social thought for the informal neighborhood of El Pozón, located in the periphery of the Colombian city of Cartagena de Indias. The project is based on the reinterpretation of the Caribbean house, starting from a study of the user needs, integrating industrial technologies - like the steel frame- and artisanal technologies -such as the tejidos in the façade-, with a strategy to reduce the environmental impact of the building in its life cycle. In December 2019 Máquina Verde - El Arca was built and tested by the students and professors of the two universities during the final phase of the Solar Decathlon in Cali, Colombia. The collaboration in the international competition was born as an innovative training activity based on PBL (Problem Based Learning) and “learning by doing” methodologies and has evolved into a shared research about the issues of environmental, social and economic sustainability for the architecture of social interest of the Latin American cities