Orientational relaxations in solid (1,1,2,2)tetrachloroethane

We employ dielectricspectroscopy and molecular dynamic simulations to investigate the dipolar dynamics in the orientationally disordered solid phase of (1,1,2,2)tetrachloroethane. Three distinct orientational dynamics are observed as separate dielectric loss features, all characterized by a simply activated temperature dependence. The slower process, associated to a glassytransition at 156 ± 1 K, corresponds to a cooperative motion by which each molecule rotates by 180° around the molecular symmetry axis through an intermediate state in which the symmetry axis is oriented roughly orthogonally to the initial and final states. Of the other two dipolar relaxations, the intermediate one is the Johari-Goldstein precursor relaxation of the cooperative dynamics, while the fastest process corresponds to an orientational fluctuation of single molecules into a higher-energy orientation. The Kirkwood correlation factor of the cooperative relaxation is of the order of one tenth, indicating that the molecular dipoles maintain on average a strong antiparallel alignment during their collective motion. These findings show that the combination of dielectricspectroscopy and molecular simulations allows studying in great detail the orientational dynamics in molecular solids.Peer ReviewedPostprint (author's final draft

Effectiveness of a Wii balance board-based system (eBaViR) for balance rehabilitation: a pilot randomized clinical trial in patients with acquired brain injury

Background: Acquired brain injury (ABI) is the main cause of death and disability among young adults. In most cases, survivors can experience balance instability, resulting in functional impairments that are associated with diminished health-related quality of life. Traditional rehabilitation therapy may be tedious. This can reduce motivation and adherence to the treatment and thus provide a limited benefit to patients with balance disorders. We present eBaViR (easy Balance Virtual Rehabilitation), a system based on the Nintendo¿ Wii Balance Board¿ (WBB), which has been designed by clinical therapists to improve standing balance in patients with ABI through motivational and adaptative exercises. We hypothesize that eBaViR, is feasible, safe and potentially effective in enhancing standing balance. Methods. In this contribution, we present a randomized and controlled single blinded study to assess the influence of a WBB-based virtual rehabilitation system on balance rehabilitation with ABI hemiparetic patients. This study describes the eBaViR system and evaluates its effectiveness considering 20 one-hour-sessions of virtual reality rehabilitation (n = 9) versus standard rehabilitation (n = 8). Effectiveness was evaluated by means of traditional static and dynamic balance scales. Results: The final sample consisted of 11 men and 6 women. Mean ±SD age was 47.3 ± 17.8 and mean SD chronicity was 570.9 ± 313.2 days. Patients using eBaViR had a significant improvement in static balance (p = 0.011 in Berg Balance Scale and p = 0.011 in Anterior Reaches Test) compared to patients who underwent traditional therapy. Regarding dynamic balance, the results showed significant improvement over time in all these measures, but no significant group effect or group-by-time interaction was detected for any of them, which suggests that both groups improved in the same way. There were no serious adverse events during treatment in either group. Conclusions: The results suggest that eBaViR represents a safe and effective alternative to traditional treatment to improve static balance in the ABI population. These results have encouraged us to reinforce the virtual treatment with new exercises, so an evolution of the system is currently being developed. © 2011 Gil-Gómez et al; licensee BioMed Central Ltd.This study was funded in part by Ministerio de Educacion y Ciencia Spain, Projects Consolider-C (SEJ2006-14301/PSIC), "CIBER of Physiopathology of Obesity and Nutrition, an initiative of ISCIII" and the Excellence Research Program PROMETEO (Generalitat Valenciana. Conselleria de Educacion, 2008-157).Gil-Gómez, J.; Llorens Rodríguez, R.; Alcañiz Raya, ML.; Colomer Font, C. (2011). Effectiveness of a Wii balance board-based system (eBaViR) for balance rehabilitation: a pilot randomized clinical trial in patients with acquired brain injury. Journal of NeuroEngineering and Rehabilitation. 8(30):1-9. https://doi.org/10.1186/1743-0003-8-30S19830Nichols-Larsen, D. S., Clark, P. C., Zeringue, A., Greenspan, A., & Blanton, S. (2005). Factors Influencing Stroke Survivors’ Quality of Life During Subacute Recovery. Stroke, 36(7), 1480-1484. doi:10.1161/01.str.0000170706.13595.4fTeasell, R., Meyer, M. J., McClure, A., Pan, C., Murie-Fernandez, M., Foley, N., & Salter, K. (2009). Stroke Rehabilitation: An International Perspective. Topics in Stroke Rehabilitation, 16(1), 44-56. doi:10.1310/tsr1601-44Sveistrup, H. (2004). Journal of NeuroEngineering and Rehabilitation, 1(1), 10. doi:10.1186/1743-0003-1-10Holden, M. K. (2005). Virtual Environments for Motor Rehabilitation: Review. CyberPsychology & Behavior, 8(3), 187-211. doi:10.1089/cpb.2005.8.187Crosbie, J. H., Lennon, S., Basford, J. R., & McDonough, S. M. (2007). Virtual reality in stroke rehabilitation: Still more virtual than real. Disability and Rehabilitation, 29(14), 1139-1146. doi:10.1080/09638280600960909Haas, B. M., & Burden, A. M. (2000). Validity of weight distribution and sway measurements of the Balance Performance Monitor. Physiotherapy Research International, 5(1), 19-32. doi:10.1002/pri.181Srivastava, A., Taly, A. B., Gupta, A., Kumar, S., & Murali, T. (2009). Post-stroke balance training: Role of force platform with visual feedback technique. Journal of the Neurological Sciences, 287(1-2), 89-93. doi:10.1016/j.jns.2009.08.051Deutsch, J. E., Borbely, M., Filler, J., Huhn, K., & Guarrera-Bowlby, P. (2008). Use of a Low-Cost, Commercially Available Gaming Console (Wii) for Rehabilitation of an Adolescent With Cerebral Palsy. Physical Therapy, 88(10), 1196-1207. doi:10.2522/ptj.20080062Yong Joo, L., Soon Yin, T., Xu, D., Thia, E., Pei Fen, C., Kuah, C., & Kong, K. (2010). A feasibility study using interactive commercial off-the-shelf computer gaming in upper limb rehabilitation in patients after stroke. Journal of Rehabilitation Medicine, 42(5), 437-441. doi:10.2340/16501977-0528Clark, R. A., Bryant, A. L., Pua, Y., McCrory, P., Bennell, K., & Hunt, M. (2010). Validity and reliability of the Nintendo Wii Balance Board for assessment of standing balance. Gait & Posture, 31(3), 307-310. doi:10.1016/j.gaitpost.2009.11.012Young, W., Ferguson, S., Brault, S., & Craig, C. (2011). Assessing and training standing balance in older adults: A novel approach using the ‘Nintendo Wii’ Balance Board. Gait & Posture, 33(2), 303-305. doi:10.1016/j.gaitpost.2010.10.089Shih, C.-H., Shih, C.-T., & Chiang, M.-S. (2010). A new standing posture detector to enable people with multiple disabilities to control environmental stimulation by changing their standing posture through a commercial Wii Balance Board. Research in Developmental Disabilities, 31(1), 281-286. doi:10.1016/j.ridd.2009.09.013Shih, C.-H., Shih, C.-T., & Chu, C.-L. (2010). Assisting people with multiple disabilities actively correct abnormal standing posture with a Nintendo Wii Balance Board through controlling environmental stimulation. Research in Developmental Disabilities, 31(4), 936-942. doi:10.1016/j.ridd.2010.03.004Folstein, M. F., Folstein, S. E., & McHugh, P. R. (1975). «Mini-mental state». Journal of Psychiatric Research, 12(3), 189-198. doi:10.1016/0022-3956(75)90026-6Geurts, A. C. H., de Haart, M., van Nes, I. J. W., & Duysens, J. (2005). A review of standing balance recovery from stroke. Gait & Posture, 22(3), 267-281. doi:10.1016/j.gaitpost.2004.10.002Marsden, J. F. (2005). The vestibular control of balance after stroke. Journal of Neurology, Neurosurgery & Psychiatry, 76(5), 670-679. doi:10.1136/jnnp.2004.046565Perron, M., Malouin, F., & Moffet, H. (2003). Assessing advanced locomotor recovery after total hip arthroplasty with the timed stair test. Clinical Rehabilitation, 17(7), 780-786. doi:10.1191/0269215503cr696oaMcDowell, B. C., Kerr, C., Parkes, J., & Cosgrove, A. (2005). Validity of a 1 minute walk test for children with cerebral palsy. Developmental Medicine & Child Neurology, 47(11), 744. doi:10.1017/s0012162205001568O’Shea, S. D., Taylor, N. F., & Paratz, J. D. (2007). Measuring Muscle Strength for People With Chronic Obstructive Pulmonary Disease: Retest Reliability of Hand-Held Dynamometry. Archives of Physical Medicine and Rehabilitation, 88(1), 32-36. doi:10.1016/j.apmr.2006.10.002Tyson, S. F., Hanley, M., Chillala, J., Selley, A. B., & Tallis, R. C. (2007). The Relationship Between Balance, Disability, and Recovery After Stroke: Predictive Validity of the Brunel Balance Assessment. Neurorehabilitation and Neural Repair, 21(4), 341-346. doi:10.1177/1545968306296966Brooks, D., Davis, A. M., & Naglie, G. (2006). Validity of 3 Physical Performance Measures in Inpatient Geriatric Rehabilitation. Archives of Physical Medicine and Rehabilitation, 87(1), 105-110. doi:10.1016/j.apmr.2005.08.109Jørgensen, H. S., Nakayama, H., Raaschou, H. O., Vive-Larsen, J., Støier, M., & Olsen, T. S. (1995). Outcome and time course of recovery in stroke. Part II: Time course of recovery. The copenhagen stroke study. Archives of Physical Medicine and Rehabilitation, 76(5), 406-412. doi:10.1016/s0003-9993(95)80568-0Ferrarello, F., Baccini, M., Rinaldi, L. A., Cavallini, M. C., Mossello, E., Masotti, G., … Di Bari, M. (2010). Efficacy of physiotherapy interventions late after stroke: a meta-analysis. Journal of Neurology, Neurosurgery & Psychiatry, 82(2), 136-143. doi:10.1136/jnnp.2009.19642

Does CEO media exposure affect corporate social responsibility?

[EN] Given the central role played by CEOs in the arena of strategic decision making, thisarticle focuses on their impact on the implementation of socially responsible initia-tives, which try to comply with the stakeholders' demands. Specifically, and drawingupon the relevant influence of media on decision makers, we analysed how CEOs'media exposure affects the development of their companies' corporate social respon-sibility (CSR) practices. Moreover, relying mainly on the agency and stakeholder the-ories, we also considered a potential moderating effect of other CEO characteristics.The results of the hierarchical regression analysis carried out on a sample of 60 pub-licly listed Spanish companies in 2014 suggest that greater CEO media exposure canlead to a greater commitment to CSR. Furthermore, it was observed that this relation-ship may be affected by CEO tenure and prior political experience.SIThe authors acknowledge the financial support by the Ministerio deEconomía y Competitividad del Gobierno de España (research projects ECO2015‐63880‐R and ECO2015‐69058‐R

High-activity mesoporous Pt/Ru catalysts for methanol oxidation

High activity mesoporous Pt/Ru catalysts with 2D-hexagonal structure were synthesized using a triblock poly(ethylene oxide)-b-poly(propylene oxide)-b-poly(ethylene oxide) copolymer (Pluronic F127) template. The normalized mass activities for the methanol oxidation reaction (MOR) of the Pt/Ru catalysts with a regular array of pores is higher than those reported for nanoparticulated Pt/Ru catalysts. Different kinetic parameters, as Tafel slope and activation energy, were obtained for the MOR on the mesoporous catalysts. Results indicated that catalysts performance depends on pore size. Mass activities and the CO2 conversion efficiency for large pore size mesoporous catalysts (10 nm) are greater than those reported for smaller pore size mesoporous catalysts with similar composition. The effect of pore size on catalysts performance is related to the greater accessibility of methanol to the active areas inside large pores. Consequently, the overall residence time of methanol increases as compared with mesoporous catalyst with small pores.Fil: Franceschini, Esteban Andrés. Consejo Nacional de Investigaciones Científicas y Técnicas; Argentina. Comisión Nacional de Energía Atómica. Gerencia del Area de Investigaciones y Aplicaciones No Nucleares. Gerencia de Física (Centro Atómico Constituyentes); ArgentinaFil: Bruno, Mariano Martín. Comisión Nacional de Energía Atómica. Gerencia del Area de Investigaciones y Aplicaciones No Nucleares. Gerencia de Física (Centro Atómico Constituyentes); Argentina. Universidad Nacional de San Martín. Escuela de Ciencia y Tecnología; Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Williams, Federico José. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Química, Física de los Materiales, Medioambiente y Energía. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Instituto de Química, Física de los Materiales, Medioambiente y Energía; Argentina. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Departamento de Química Inorgánica, Analítica y Química Física; ArgentinaFil: Viva, Federico Andrés. Comisión Nacional de Energía Atómica. Gerencia del Area de Investigaciones y Aplicaciones No Nucleares. Gerencia de Física (Centro Atómico Constituyentes); Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas; ArgentinaFil: Corti, Horacio Roberto. Comisión Nacional de Energía Atómica. Gerencia del Area de Investigaciones y Aplicaciones No Nucleares. Gerencia de Física (Centro Atómico Constituyentes); Argentina. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Ciudad Universitaria. Instituto de Química, Física de los Materiales, Medioambiente y Energía. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Instituto de Química, Física de los Materiales, Medioambiente y Energía; Argentina. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales. Departamento de Química Inorgánica, Analítica y Química Física; Argentin

La sequía de mediados del siglo XVII en el valle del Ebro. Características climáticas e impacto social del evento

En este trabajo se analizan las sequías de mediados del siglo XVII en las tierras centrales del valle del Ebro y su impacto en la demografía. Mediante la recopilación de ceremonias de rogativas «ad petendam pluviam» y reconstrucciones dendroclimáticas, se ha elaborado un índice de sequía y precipitación de todo el siglo y se ha relacionado con los datos demográficos de varias localidades del interior del valle. Los resultados muestran la existencia de un acusado y largo periodo seco a mitad del siglo, prácticamente desde 1641 a 1654, interrumpido por algunos intensos temporales causantes de grandes riadas, como la que sufrió el río Ebro en febrero de 1643. La prolongada sequía se corresponde con el descenso de la natalidad y un fuerte incremento de la mortalidad.Droughts of the mid XVII century in the Central lands of the Ebro Valley and its impact on demography are analyzed in this paper. Through the collecting of rogations ceremonies «ad petendam pluviam» and dendroclimatic reconstructions, an index of drought and precipitation has been developed. In addition, it has been linked with demographic data from various locations inside the Valley. The results show the existence of a pronounced and long dry period in the middle of the century, practically from 1641 to 1654, interrupted by some intense tempests causing big floods: For instance, the flood in the Ebro River in February 1643. The prolonged drought corresponds to the decline in the birth rate and a strong increase in mortality.Este estudio se ha realizado en el marco del proyecto de investigación CGL2011-28255, financiado por el Ministerio de Economía y Competitividad del Gobierno de España, y el programa de Grupos de Investigación Consolidados «Clima, Agua y Cambio Global» del Gobierno de Aragón y Fondos FEDER. Además, Ernesto Tejedor disfruta de una beca predoctoral de investigación concedida por el Gobierno de Aragón 2012-2016

The role of virtual motor rehabilitation: a quantitative analysis between acute and chronic patients with acquired brain injury

"(c) 2014 IEEE. Personal use of this material is permitted. Permission from IEEE must be obtained for all other users, including reprinting/ republishing this material for advertising or promotional purposes, creating new collective works for resale or redistribution to servers or lists, or reuse of any copyrighted components of this work in other works."Acquired brain injury (ABI) is one of the main problems of disability and death in the world. Its incidence and survival rate are increasing annually. Thus, the number of chronic ABI patients is gradually growing. Traditionally, rehabilitation programs are applied to postacute and acute patients, but recent publications determine that chronic patients may benefit from rehabilitation. Also, in the last few years, the potential of virtual rehabilitation (VR) systems has been demonstrated. However, until now, no previous studies have been carried out to compare the evolution of chronic patients with acute patients in a VR program. To perform this study, we developed a VR system for ABI patients. The system, vestibular virtual rehabilitation (V2R), was designed with clinical specialists. V2R has been tested with 21 people ranging in age from 18 to 80 years old that were classified in two groups: chronic patients and acute patients. The results demonstrate a similar recovery for chronic and acute patients during the intervention period. Also, the results showed that chronic patients stop their improvement when they finish their training. This conclusion encourages us to direct our developments toward VR systems that can be easily integrated at home, allowing chronic patients to have a permanent VR training program.This work was supported by the Ministerio de Educacion y Ciencia Spain: Projects Consolider-C (SEJ2006-14301/PSIC), "CIBER of Physiopathology of Obesity and Nutrition, an initiative of ISCIII," and the Excellence Research Program PROMETEO (Generalitat Valenciana. Conselleria de Educacion, 2008-157).Albiol Pérez, S.; Gil-Gómez, J.; Llorens Rodríguez, R.; Alcañiz Raya, ML.; Colomer Font, C. (2014). The role of virtual motor rehabilitation: a quantitative analysis between acute and chronic patients with acquired brain injury. IEEE Journal of Biomedical and Health Informatics. 18(1):391-398. https://doi.org/10.1109/JBHI.2013.2272101S39139818

Influence of the CAD-CAM Systems on the Marginal Accuracy and Mechanical Properties of Dental Restorations

The aim of this study was to compare the quality of different computer-assisted-design and computer assisted manufacturing systems (CAD-CAM) generated by only one scanner, focusing on vertical fit discrepancies and the mechanical properties. A master model was obtained from a real clinical situation: the replacement of an absent (pontic) tooth, with the construction of a fixed partial denture on natural abutments with three elements. Nine scans were performed by each tested and 36 copies were designed using a dental CAD-CAM software (Exocad). The frameworks were manufactured using three-axis and five-axis, with the same batch of the chrome-cobalt (CrCo) alloy. The frameworks were not cemented. A focus ion beam-high resolution scanning electron microscope (FIB-HRSEM) allowed us to obtain the vertical gap measurements in five points for each specimen. Roughness parameters were measured using white light interferometry (WLI). The samples were mechanically characterized by means of flexural tests. A servo-hydraulic testing machine was used with a cross-head rate of 1 mm/min. One-way ANOVA statistical analysis was performed to determine whether the vertical discrepancies and mechanical properties were significantly different between each group (significance level p < 0.05). The overall mean marginal gap values ranged: from 92.38 ± 19.24 µm to 19.46 ± 10.20 µm, for the samples produced by three-axis and five-axis machines, respectively. Roughness was lower in the five-axis machine than the three-axis one, and as a consequence, the surface quality was better when the five-axis machine was used. These results revealed a statistically significant difference (p < 0.005) in the mean marginal gap between the CAD-CAM systems studied. The flexural strength for these restorations range from 6500 to 7000 N, and does not present any statistical differences’ significance between two CAD-CAM systems studied. This contribution suggests that the number of axes improves vertical fit and surface quality due to the lower roughness. These claims show some discrepancies with other studies

Aplicación de laboratorios virtuales en la carrera de Ingeniería en Telecomunicaciones, UNED

The application of virtual and remote laboratories in Telecommunications Engineering is essential in its 100% virtual education model, since its inception in 2016. The objective of this work is to evaluate the results obtained and the mechanism of their application. The methodology applied was qualitative under a grounded theory design, where the results are contrasted with the theory and the authors are an active part of the process. The main results are the positive evaluation by the graduates of the course and the generation of significant learning through innovative mediation. The main conclusion is that the laboratories have fulfilled their objective and that the mediation is innovative. It is recommended that the course should be constantly updated and give more flexibility in mediation.La aplicación de laboratorios virtuales y remotos en la Ingeniería en Telecomunicaciones es esencial en su modelo de educación 100 % virtual, desde su inicio en el 2016. El objetivo de este trabajo es valorar los resultados que se han obtenido y el mecanismo de aplicación de estos. La metodología aplicada fue cualitativa bajo un diseño de teoría – fundamentada, donde los resultados se contraponen a la teoría y los autores son parte actora del proceso. Los principales resultados son la valoración positiva por parte de los egresados de la carrera y la generación de aprendizajes significativos por medio de una mediación innovadora. La principal conclusión es que los laboratorios han cumplido con su objetivo y que la mediación es innovadora. Se recomienda a la carrera la actualización constante y dar más flexibilidad en la mediación

Environmental conditions in river segments intercepted by culverts

The conservation and maintenance of the quality of the rheophilic environment are directly related to knowledge of the physical and chemical characteristics and structural patterns of these systems, especially in streams. Long stretches of small water bodies are highly altered by the construction of highways and roads, which tend to modify their natural characteristics, affecting the environmental quality. This study describes vegetation and morphogeometric parameters of streams with culverts along their courses, reporting spatial differences in environmental characteristics (vegetation, morphogeometric, physical, and chemical) between sampling points upstream and downstream of the culvert. Specifically, we evaluated the width, depth, riparian vegetation, substrate background, and physical and chemical properties of the water, to identify possible differences between the sections above and below (upstream and downstream) of the culvert. The rapid assessment protocol (RAP) was applied to stretches of 200 meters upstream and downstream of culverts in two Neotropical streams, between the months of November 2009 and October 2010. The vegetation and morphogeometric attributes differed between the portions upstream and downstream of the culverts, the latter because of the impoundment effect of these structures. The upstream section becomes flooded, is often shallow, and directly influences the movement of sediment. The physical and chemical variables of the water showed no spatial variation.(Condições ambientais de segmentos fluviais interceptados por bueiros). A conservação e a manutenção da qualidade ambiental do ambiente reofílico está diretamente relacionada ao conhecimento de características físicas e químicas e dos padrões estruturais destes sistemas, especialmente em riachos. Longos trechos de pequenos corpos aquáticos são altamente alterados pela construção de rodovias e estradas e tende a modificar as suas características naturais, interferindo na qualidade ambiental. Neste sentido, o objetivo deste estudo foi descrever parâmetros fito-morfogeométricos de riachos com bueiros em seu curso longitudinal, reportando diferenças espaciais nas características ambientais (fito-morfogeométricos e físico-químicas) entre os pontos amostrados (montante e jusante do bueiro). Especificamente, avaliamos a largura, a profundidade, vegetação ripária, substrato de fundo e atributos físicos e químicos da água, verificando as possíveis divergências entre os trechos de acima e abaixo (montante e jusante) do bueiro. Para isso, o protocolo de avaliação rápida (PAR) foi aplicado em trechos de 200 metros a montante, bem como a jusante de bueiros em dois riachos neotropicais entre os meses de novembro de 2009 e outubro de 2010. Verificou-se que os atributos fito-morfogeométricos diferem entre os trechos de montante e jusante, pois o bueiro tem efeito de represamento. Esse fato transforma o trecho a montante em ambiente alagado, muitas vezes rasos e influenciando diretamente o movimento de sedimentos. As variáveis físicas e químicas da água não apresentaram variação espacial

Clinical factors influencing long-term survival in a real-life cohort of early stage non-small-cell lung cancer patients in Spain

Funding Information: This work was supported in part by Centro de Matematica e Aplicaçoes, UID (MAT/00297/2020), Portuguese Foundation of Science and Technology. Acknowledgments Publisher Copyright: Copyright © 2023 Torrente, Sousa, Guerreiro, Franco, Hernández, Parejo, Sousa, Campo-Cañaveral, Pimentão and Provencio.Background: Current prognosis in oncology is reduced to the tumour stage and performance status, leaving out many other factors that may impact the patient´s management. Prognostic stratification of early stage non-small-cell lung cancer (NSCLC) patients with poor prognosis after surgery is of considerable clinical relevance. The objective of this study was to identify clinical factors associated with long-term overall survival in a real-life cohort of patients with stage I-II NSCLC and develop a prognostic model that identifies features associated with poor prognosis and stratifies patients by risk. Methods: This is a cohort study including 505 patients, diagnosed with stage I-II NSCLC, who underwent curative surgical procedures at a tertiary hospital in Madrid, Spain. Results: Median OS (in months) was 63.7 (95% CI, 58.7-68.7) for the whole cohort, 62.4 in patients submitted to surgery and 65 in patients submitted to surgery and adjuvant treatment. The univariate analysis estimated that a female diagnosed with NSCLC has a 0.967 (95% CI 0.936 - 0.999) probability of survival one year after diagnosis and a 0.784 (95% CI 0.712 - 0.863) five years after diagnosis. For males, these probabilities drop to 0.904 (95% CI 0.875 - 0.934) and 0.613 (95% CI 0.566 - 0.665), respectively. Multivariable analysis shows that sex, age at diagnosis, type of treatment, ECOG-PS, and stage are statistically significant variables (p1) while adjuvant chemotherapy is a good prognostic variable (HR<1). The prognostic model identified a high-risk profile defined by males over 71 years old, former smokers, treated with surgery, ECOG-PS 2. Conclusions: The results of the present study found that, overall, adjuvant chemotherapy was associated with the best long-term OS in patients with resected NSCLC. Age, stage and ECOG-PS were also significant factors to take into account when making decisions regarding adjuvant therapy.publishersversionpublishe