1,593 research outputs found
Turbo EP-based Equalization: a Filter-Type Implementation
This manuscript has been submitted to Transactions on Communications on
September 7, 2017; revised on January 10, 2018 and March 27, 2018; and accepted
on April 25, 2018
We propose a novel filter-type equalizer to improve the solution of the
linear minimum-mean squared-error (LMMSE) turbo equalizer, with computational
complexity constrained to be quadratic in the filter length. When high-order
modulations and/or large memory channels are used the optimal BCJR equalizer is
unavailable, due to its computational complexity. In this scenario, the
filter-type LMMSE turbo equalization exhibits a good performance compared to
other approximations. In this paper, we show that this solution can be
significantly improved by using expectation propagation (EP) in the estimation
of the a posteriori probabilities. First, it yields a more accurate estimation
of the extrinsic distribution to be sent to the channel decoder. Second,
compared to other solutions based on EP the computational complexity of the
proposed solution is constrained to be quadratic in the length of the finite
impulse response (FIR). In addition, we review previous EP-based turbo
equalization implementations. Instead of considering default uniform priors we
exploit the outputs of the decoder. Some simulation results are included to
show that this new EP-based filter remarkably outperforms the turbo approach of
previous versions of the EP algorithm and also improves the LMMSE solution,
with and without turbo equalization
SoNeUCONADM: the administrative model for SoNeUCONABC usage control model
The popularity of Web Based Social Networks (WBSNs) encourages their enhancement. Many WBSN data is considered personal data and access control management plays a key role in this regard. The point is not only to manage access control but to determine how administration should be performed. Based on SoNeUCONABC, an expressive usage control model that allows fine-grained access control management, this paper presents SoNeUCONADM, the complementary administrative model. Based on a pair of related and popular administrative models, the evaluation proves the completeness of SoNeUCONADM
Neuroglial involvement in abnormal glutamate transport in the cochlear nuclei of the Igf1—/— mouse
Insulin-like growth factor 1 (IGF-1) is a powerful regulator of synaptic activity and a
deficit in this protein has a profound impact on neurotransmission, mostly on excitatory
synapses in both the developing and mature auditory system. Adult Igf1—/— mice
are animal models for the study of human syndromic deafness; they show altered
cochlear projection patterns into abnormally developed auditory neurons along with
impaired glutamate uptake in the cochlear nuclei, phenomena that probably reflect
disruptions in neuronal circuits. To determine the cellular mechanisms that might
be involved in regulating excitatory synaptic plasticity in 4-month-old Igf1—/— mice,
modifications to neuroglia, astroglial glutamate transporters (GLTs) and metabotropic
glutamate receptors (mGluRs) were assessed in the cochlear nuclei. The Igf1—/— mice
show significant decreases in IBA1 (an ionized calcium-binding adapter) and glial
fibrillary acidic protein (GFAP) mRNA expression and protein accumulation, as well
as dampened mGluR expression in conjunction with enhanced glutamate transporter
1 (GLT1) expression. By contrast, no differences were observed in the expression
of glutamate aspartate transporter (GLAST) between these Igf1—/— mice and their
heterozygous or wildtype littermates. These observations suggest that congenital IGF-1
deficiency may lead to alterations in microglia and astrocytes, an upregulation of GLT1,
and the downregulation of groups I, II and III mGluRs. Understanding the molecular,
biochemical and morphological mechanisms underlying neuronal plasticity in a mouse
model of hearing deficits will give us insight into new therapeutic strategies that could
help to maintain or even improve residual hearing when human deafness is related to
IGF-1 deficiencyThis work was supported by the Spanish Ministerio de Economía
y Competitividad (MINECO; SAF2016-788898-C2-1R) to JJ and
VF-S; Seventh Framework Programme (FP7)-HEALTH-
2012-INNOVATON (#304925) to JJ; CIBERER/FEDER
ACCI-ER16P5AC7091 and ER17P5AC7612 to LR-R;
and Spanish MINECO/FEDER (SAF2014-53979-R), FP7-
PEOPLE-2013-IAPP TARGEAR, CIBERER/FEDER (ACCIER16P5AC7091
and ER17P5AC7612) to IV-N. LR-R holds a
contract supported by CIBERER (Institute of Health Carlos III)
co-financed with FEDER fund
A study of eosinophilia and helminths in migrant sub-Saharan patients in a primary care center (Madrid, Spain)
We determine the association between eosinophilia and certain parasites diagnosed by serology in patients of subsaharan origin of a Primary Care Center from Madrid region, Spain. It was implemented a complete protocol for migrant patient to study eosinophilia and realized serology tests for parasites detection. All variable and data were evaluated by statistical methods. A total of 184 patients with eosinophilia were included in the study, 115 patients (62.5%) were seronegative for helminths and 69 were seropositive. Strongyloides stercoralis (55.07%), Schistosoma spp (39.13%) and Toxocara canis (20.29%) were the most prevalent helminths immunodetected in the study. So, 49 patients (26.6%) had abdominal pain, 50 patients (27.17%) had problems related with skin conditions and 38 patients (20.65%) had respiratory disorder, symptoms not related with the helminth parasites detected. Regarding number of parasites by patient, one specie was identified in 49 patients (26.63%) and two or more was identified in 20 patients (10.86%). Eosinophilia was resolved in 91.4% of parasite serpositive patients after received one specific adequate antiparasitic treatment, but this was resolved in 98.3% after received two tratments, and 100% after the third. The results obtained allow us to make some reflections on the difficulty of managing these patients in the Primary Care Center and on whether to diagnose and treat individuals from endemic areas, with or without eosinophilia and being asymptomatic or not, given the benefit it has for the individual and public health, as possible to minimize any chance of transmission
Analysis of the Gálvez–Davison Index for the forecasting formation and evolution of convective clouds in the tropics: Western Cuba
The Gálvez–Davison Index (GDI) is an atmospheric stability index recently developed to improve the prediction of thunderstorms and shallower types of moist convection in the tropics. Because of its novelty, its use for tropical regions remains largely unexplored. Cuba is a region that suffers extreme weather events, such as tropical storms and hurricanes, some of them worsened by climate change. This research analyzes the effectiveness of the GDI in detecting the potential for convective cloud development, using forecast data from the Weather Research and Forecasting (WRF) model for Western Cuba. To accomplish this, here, we evaluated the performance of the GDI in ten study cases from the dry and wet seasons. As part of our study, we researched how GDI correlates with brightness temperatures (BTs) measured using GOES-16. In addition, the GDI results with the WRF model are compared with results using the Global Forecast System (GFS). Our results show a high correlation between the GDI and BT, concluding that the GDI is a robust tool for forecasting both synoptic and mesoscale convective phenomena over the region studied. In addition, the GDI is able to adequately forecast stability conditions. Finally, the GDI values computed from the WRF model perform much better than those from the GFS, probably because of the greater horizontal resolution in the WRF model.Xunta de Galicia | Ref. ED431C 2021/44Xunta de Galicia | Ref. ED481A-2020/19
Kinematic characteristics of the long jump approach run in paralympic-level male limb-deficients
The purpose of this study was to define the variables typifying the long jump approach run phase in paralympic-level male amputees. The sample comprised of the eleven (4 transtibial, 5 transfemoral and 2 single below-the-knee amputees). The parameters analysed were: official distance, toe-to-board distance, effective distance, stride contact time, stride flight time, total stride time, stride length, stride frequency, stride velocity, horizontal velocity, vertical velocity, resultant velocity, height of body center of mass, take-off stride angle, relative differences in stride length and relative differences in stride frequency. The findings of the study revealed that 77.8% of the para-athletes perform the take-off with the leg supported by the prosthesis. Horizontal velocity during the last three strides before take-off has been shown to have a high correlation with the official jump distance: 3rd last (r=0.65, p<0.05), 2nd last (r=0.69, p<0.05) and last (r=0.67, p<0.05) strides. Stride length and stride frequency patterns for the 3rd, 2nd and last strides were as follows: medium-long-short and high-low-high. Horizontal velocity at the last stride is higher compared to the preceding two. The findings of the study support the notion that a wide range of similarities exist in the running patterns and factors correlating with jumping distance between Paralympic amputee athletes and able-bodied high-level athletes
Discriminating the short-term action of root and foliar application of humic acids on plant growth: emerging role of jasmonic acid
Humic substances (HS, fulvic and humic acids) are widely used as fertilizers or plant growth stimulants, although their mechanism of action still remains partially unknown. Humic substances may be applied either directly to the soil or as foliar sprays. Despite both kind of application are commonly used in agricultural practices, most of the studies regarding the elicited response in plants induced by HS are based on the root-application of these substances. The present work aimed at discriminating between the mechanisms of action of foliar application versus root application of a sedimentary humic acid (SHA) on plant development. For this purpose, six markers related to plant phenotype, plant morphology, hormonal balance and root-plasma membrane H+-ATPase were selected. Both application strategies improved the shoot and root growth. Foliar applied- and root applied-SHA shared the capacity to increase the concentration of indole-3-acetic acid in roots and cytokinins in shoots. However, foliar application did not lead to short-term increases in either abscisic acid root-concentration or root-plasma membrane H+-ATPase activity which are, however, two crucial effects triggered by SHA root-application. Both application modes increased the root concentrations of jasmonic acid and jasmonoyl-isoleucine. These hormonal changes caused by foliar application could be a stress-related symptom and connected to the loss of leaves trichomes and the diminution of chloroplasts size seen by scanning electron microscopy. These results support the hypothesis that the beneficial effects of SHA applied to roots or leaves may result from plant adaptation to a mild transient stress caused by SHA application
Aerosol characterization at the Saharan AERONET site Tamanrasset
More than 2 years of columnar atmospheric aerosol measurements (2006–2009) at the Tamanrasset site (22.79° N, 5.53° E, 1377 m a.s.l.), in the heart of the Sahara, are analysed. Aerosol Robotic Network (AERONET) level 2.0 data were used. The KCICLO (K is the name of a constant and ciclo means cycle in Spanish) method was applied to a part of the level 1.5 data series to improve the quality of the results. The annual variability of aerosol optical depth (AOD) and Ångström exponent (AE) has been found to be strongly linked to the convective boundary layer (CBL) thermodynamic features. The dry-cool season (autumn and winter) is characterized by a shallow CBL and very low mean turbidity (AOD ~ 0.09 at 440 nm, AE ~ 0.62). The wet-hot season (spring and summer) is dominated by high turbidity of coarse dust particles (AE ~ 0.28, AOD ~ 0.39 at 440 nm) and a deep CBL. The aerosol-type characterization shows desert mineral dust as the prevailing aerosol. Both pure Saharan dust and very clear sky conditions are observed depending on the season. However, several case studies indicate an anthropogenic fine mode contribution from the industrial areas in Libya and Algeria. The concentration weighted trajectory (CWT) source apportionment method was used to identify potential sources of air masses arriving at Tamanrasset at several heights for each season. Microphysical and optical properties and precipitable water vapour were also investigated.The AERONET sun photometer at Tamanrasset has been calibrated within AERONET-EUROPE TNA supported by the PHOTONS and RIMA networks and partially financed by the European Community – Research Infrastructure Action under the Seventh Framework Programme (FP7/2007-2013) “Capacities” specific programme for Integrating Activities, ACTRIS grant agreement no. 262254.
Financial support from the Spanish MINECO (projects CGL2011-23413, CGL2012-33576 and CGL2012-37505) is also gratefully acknowledged.
J. M. Baldasano and S. Basart acknowledge the Supercomputación y eCiencia project (CSD2007-0050) from the Consolider-Ingenio 2010 and Severo Ochoa (SEV-2011-00067) programs of the Spanish Government
Acetylome in Human Fibroblasts From Parkinson's Disease Patients
Parkinson's disease (PD) is a multifactorial neurodegenerative disorder. The pathogenesis of this disease is associated with gene and environmental factors. Mutations in leucine-rich repeat kinase 2 (LRRK2) are the most frequent genetic cause of familial and sporadic PD. Moreover, posttranslational modifications, including protein acetylation, are involved in the molecular mechanism of PD. Acetylation of lysine proteins is a dynamic process that is modulated in PD. In this descriptive study, we characterized the acetylated proteins and peptides in primary fibroblasts from idiopathic PD (IPD) and genetic PD harboring G2019S or R1441G LRRK2 mutations. Identified acetylated peptides are modulated between individuals' groups. Although acetylated nuclear proteins are the most represented in cells, they are hypoacetylated in IPD. Results display that the level of hyperacetylated and hypoacetylated peptides are, respectively, enhanced in genetic PD and in IPD cells
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