3,348 research outputs found

    Effects of patch-size on populations of intertidal limpets, Siphonaria spp., in a linear landscape

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    Organisms with different life-histories and abilities to disperse often utilise habitat patches in different ways. We investigated the influence of the size of patches of rock (separated by stretches of sand) on the density of pulmonate limpets (Siphonaria spp.) along 1500 km of the linear landscape of the South African coastline. We compared the influence of patch-size on two congeneric species with different modes of development, S. serrata a direct developer, and S. concinna a planktonic developer. We tested the spatial and temporal consistency of the effects of patch-size by sampling 7 independent regions spanning the distributional range of both species of limpets, and by sampling one region at monthly intervals for 1 year. Within each region or month, 4 small patches (60 m in length) were sampled. Across the entire geographic range and throughout the year, there were more of both species of limpets in large patches than in small patches. In most regions, there was greater variability in large patches than small patches. Variability within patches in a single region was similar throughout the year, with greater variability of both species in large than in small patches. We found little influence of the mode of development on the response of limpets to patch-size. Our findings highlight the importance of understanding patterns of distribution of species with respect to habitat heterogeneity in linear landscapes, and contradict the idea that organism mobility at an early ontogenetic stage directly affects habitat use

    Approaches to Studying: A Cross-Sectional Comparison of Occupational Therapy Students in Six Education Programs in Norway

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    Students’ approaches to studying have been associated with their academic performance. Although previous research suggests that the cultural and educational context may influence approaches to studying, few studies have investigated differences in study approaches across education programs. The aim of this study was to examine whether approaches to studying differed among occupational therapy students enrolled in six different educational programs in Norway. From a population of 308 students, 187 first-year occupational therapy students in six educational programs in Norway were recruited. The students provided their sociodemographic information and completed the Approaches and Study Skills Inventory for Students (ASSIST), and group differences were analyzed with Chi-square tests and one-way analyses of variance. Scores on the deep and surface approach scales did not differ significantly among the students in the six educational programs, while there was an overall difference in scores on the strategic approach scale. Group differences regarding the subscales were minor, and only a few of the pairwise differences reached statistical significance. Differences at the education program level appear not to be important for the interpretation of differences in study approaches among students

    Love in education: West Australian early childhood pre-service teachers\u27 perspectives on children\u27s right to be loved and its actualisation within their future practice

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    Children\u27s right to love is a recognised fundamental human need set down within the 1992 United Nations Convention on the Rights of the Child. This recognition stems from an acknowledgement that the Early Years of Development are emotionally driven (Degotardi, S., & Sweller, N. (2012). Mind-mindedness in infant child-care: Associations with early childhood practitioner sensitivity and stimulation. Early Childhood Research Quarterly, 27(2), 253–265. doi:10.1016/j.ecresq.2011.09.002.). Young children respond best to those with whom they experience love and acceptance (Carter, M. A., & Fewster, C. (2013). Diversifying early years’ professional learning: One size no longer fits all. Australasian Journal of Early Childhood, 38(1), 73–⁠80.). As such, love in the classroom is important as an empowering agent of children\u27s well-being and achievement. Children’s need and right to be surrounded by love poses a challenge for many early childhood teachers as they strive to meet the emotional needs of children within a professional care-based relationship (Goldstein, J. (2012). Children’s development, health and well-being. Waterloo, Brussels: Toy Industries of Europe (TIE); Walsh, K., & Brandon, L. (2012). Their children’s first educators: Parents’ views about child sexual abuse prevention education. Journal of Child and Family Studies, 21(5), 734–746. doi:10.1007/s10826-011-9526-4.). This research presents pre-service teachers’ perspectives on love in early childhood education; their definitions, their understanding of its role within the development, and their visions of how it can be actualised within their practice

    Digital Repository, Institutional Repository, DigitalCommons

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    The University of Texas School of Nursing at Houston and HAM-TMC Library discuss the benefits of an institutional repository, DigitalCommons, and cover initial steps to create accounts and publish to the institutions DigitalCommons

    Early Life Risk Factors for Incident Atrial Fibrillation in the Helsinki Birth Cohort Study

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    Background-Early life risk factors are associated with cardiometabolic disease, but have not been fully studied in atrial fibrillation (AF). There are discordant results from existing studies of birth weight and AF, and the impact of maternal body size, gestational age, placental size, and birth length is unknown. Methods and Results-The Helsinki Birth Cohort Study includes 13 345 people born as singletons in Helsinki in the years 1934-1944. Follow-up was through national registries, and ended on December 31, 2013, with 907 incident cases. Cox regression analyses stratified on year of birth were constructed for perinatal variables and incident AF, adjusting for offspring sex, gestational age, and socioeconomic status at birth. There was a significant U-shaped association between birth weight and AF (P for quadratic term = 0.01). The lowest risk of AF was found among those with a birth weight of 3.4 kg (3.8 kg for women [85th percentile] and 3.0 kg for men [17th percentile]). High maternal body mass index (>= 30 kg/m(2)) predicted offspring AF; hazard ratio 1.36 (95% CI 1.07-1.74, P = 0.01) compared with normal body mass index ( Conclusions-High maternal body mass index during pregnancy and maternal height are previously undescribed predictors of offspring AF. Efforts to prevent maternal obesity might reduce later AF in offspring. Birth weight has a U-shaped relation to incident AF independent of other perinatal variables.Peer reviewe

    Putting It All Together

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    Putting it all together: technology design drivers to move your classroom from your campus to the world This workshop will introduce methodologies available for moving the current “classroom” mindset to a learning environment without boundaries. Participants will explore the design drivers necessary to create the technology supports for transcendent learning environments

    Hierarchical Star Formation in Nearby LEGUS Galaxies

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    Hierarchical structure in ultraviolet images of 12 late-type LEGUS galaxies is studied by determining the numbers and fluxes of nested regions as a function of size from ~1 to ~200 pc, and the number as a function of flux. Two starburst dwarfs, NGC 1705 and NGC 5253, have steeper number-size and flux-size distributions than the others, indicating high fractions of the projected areas filled with star formation. Nine subregions in 7 galaxies have similarly steep number-size slopes, even when the whole galaxies have shallower slopes. The results suggest that hierarchically structured star-forming regions several hundred parsecs or larger represent common unit structures. Small galaxies dominated by only a few of these units tend to be starbursts. The self-similarity of young stellar structures down to parsec scales suggests that star clusters form in the densest parts of a turbulent medium that also forms loose stellar groupings on larger scales. The presence of super star clusters in two of our starburst dwarfs would follow from the observed structure if cloud and stellar subregions more readily coalesce when self-gravity in the unit cell contributes more to the total gravitational potential.Comment: 9 pages, 4 figures, accepted for ApJ

    Joint analysis of stressors and ecosystem services to enhance restoration effectiveness

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    With increasing pressure placed on natural systems by growing human populations, both scientists and resource managers need a better understanding of the relationships between cumulative stress from human activities and valued ecosystem services. Societies often seek to mitigate threats to these services through large-scale, costly restoration projects, such as the over one billion dollar Great Lakes Restoration Initiative currently underway. To help inform these efforts, we merged high-resolution spatial analyses of environmental stressors with mapping of ecosystem services for all five Great Lakes. Cumulative ecosystem stress is highest in near-shore habitats, but also extends offshore in Lakes Erie, Ontario, and Michigan. Variation in cumulative stress is driven largely by spatial concordance among multiple stressors, indicating the importance of considering all stressors when planning restoration activities. In addition, highly stressed areas reflect numerous different combinations of stressors rather than a single suite of problems, suggesting that a detailed understanding of the stressors needing alleviation could improve restoration planning. We also find that many important areas for fisheries and recreation are subject to high stress, indicating that ecosystem degradation could be threatening key services. Current restoration efforts have targeted high-stress sites almost exclusively, but generally without knowledge of the full range of stressors affecting these locations or differences among sites in service provisioning. Our results demonstrate that joint spatial analysis of stressors and ecosystem services can provide a critical foundation for maximizing social and ecological benefits from restoration investments. www.pnas.org/lookup/suppl/doi:10.1073/pnas.1213841110/-/DCSupplementa

    Conversion of the LIMA1 tumour suppressor into an oncogenic LMO-like protein by API2-MALT1 in MALT lymphoma.

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    MALT1 is the only known paracaspase and is a critical mediator of B- and T-cell receptor signalling. The function of the MALT1 gene is subverted by oncogenic chimeric fusions arising from the recurrent t(11;18)(q21;q21) aberration, which is the most frequent translocation in mucosa-associated lymphoid tissue (MALT) lymphoma. API2-MALT1-positive MALT lymphomas manifest antibiotic resistance and aggressive clinical behaviour with poor clinical outcome. However, the mechanisms underlying API2-MALT1-induced MALT lymphomagenesis are not fully understood. Here we show that API2-MALT1 induces paracaspase-mediated cleavage of the tumour suppressor protein LIMA1. LIMA1 binding by API2-MALT1 is API2 dependent and proteolytic cleavage is dependent on MALT1 paracaspase activity. Intriguingly, API2-MALT1-mediated proteolysis generates a LIM domain-only (LMO)-containing fragment with oncogenic properties in vitro and in vivo. Importantly, primary MALT lymphomas harbouring the API2-MALT1 fusion uniquely demonstrate LIMA1 cleavage fragments. Our studies reveal a novel paracaspase-mediated oncogenic gain-of-function mechanism in the pathogenesis of MALT lymphoma.This work was supported in part by NIH grants R01 DE119249 and R01 CA136905 (K.S.J.E-J.), R01 CA140806 (M.S.L.) and the Department of Pathology at the University of Michigan.This is the accepted manuscript. The final version is available from Nature at http://www.nature.com/ncomms/2015/150108/ncomms6908/full/ncomms6908.html

    Climate-Smart \u3cem\u3eBrachiaria\u3c/em\u3e Grasses for Improving Livestock Production in East Africa

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    Climate change is a global phenomenon with negative impacts severely felt by poor people in developing countries (Morton 2007). Across many parts of Africa, rural poor communities rely greatly for their survival on agriculture and livestock that are amongst the most climate-sensitive economic sectors. Climate-smart agriculture helps farmers to increase food production, become more resilient to climate change and reduce greenhouse gas (GHG) emissions. The main anthro-pogenic GHGs are carbon dioxide (CO2), methane (CH4) and nitrous oxide (N2O); they are critically important for regulating the Earth’s surface temperature. Inadequate quantity and quality of feed is a major constraint to livestock production, particularly during the dry seasons across Africa. The overall objective of this inter-institutional program is to increase feed availability in action areas of the target countries in East Africa (e.g. Kenya, Rwanda) by use of climate-smart Brachiaria forage grasses (Rao et al. 2011) for increased animal productivity and for generation of extra income to smallholder famers. An innovative programmatic approach will be used to reintroduce high quality, persistent and productive Brachiaria genotypes that were selected and improved in Latin America (Miles et al. 2004) back to Africa. These forage grasses will contribute to alleviate feed shortages, increase income to resource poor farmers, improve soil fertility, adapt to and mitigate climate change, increase milk and beef production, and as a result improve livelihoods and protect the environment
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