High-precision measurement of the half-life of 62^{62}Ga

The beta-decay half-life of 62Ga has been studied with high precision using on-line mass separated samples. The decay of 62Ga which is dominated by a 0+ to 0+ transition to the ground state of 62Zn yields a half-life of T_{1/2} = 116.19(4) ms. This result is more precise than any previous measurement by about a factor of four or more. The present value is in agreement with older literature values, but slightly disagrees with a recent measurement. We determine an error weighted average value of all experimental half-lives of 116.18(4) ms.Comment: 9 pages, 5 figures, accepted for publication in PR

Topological features in the ferromagnetic Weyl semimetal CeAlSi: Role of domain walls

In the ferromagnetic (FM) Weyl semimetal CeAlSi both space-inversion and time-reversal symmetries are broken. Our quantum oscillation (QO) data indicate that the FM ordering modifies the Fermi surface topology and also leads to an unusual drop in the QO amplitude. In the FM phase, we find a pressure-induced suppression of the anomalous and the loop Hall effects. This cannot be explained based on the electronic band structure or magnetic structure, both of which are nearly pressure independent. Instead, we show that a simplified model describing the scattering of Weyl fermions off FM domain walls can potentially explain the observed topological features. Our study highlights the importance of domain walls for understanding transport in FM Weyl semimetals

The rp-process and new measurements of beta-delayed proton decay of light Ag and Cd isotopes

Recent network calculations suggest that a high temperature rp-process could explain the abundances of light Mo and Ru isotopes, which have long challenged models of p-process nuclide production. Important ingredients to network calculations involving unstable nuclei near and at the proton drip line are $\beta$-halflives and decay modes, i.e., whether or not $\beta$-delayed proton decay takes place. Of particular importance to these network calculation are the proton-rich isotopes $^{96}$Ag, $^{98}$Ag, $^{96}$Cd and $^{98}$Cd. We report on recent measurements of $\beta$-delayed proton branching ratios for $^{96}$Ag, $^{98}$Ag, and $^{98}$Cd at the on-line mass separator at GSI.Comment: 4 pages, uses espcrc1.sty. Proceedings of the 4th International Symposium Nuclei in the Cosmos, June 1996, Notre Dame/IN, USA, Ed. M. Wiescher, to be published in Nucl.Phys.A. Also available at ftp://ftp.physics.ohio-state.edu/pub/nucex/nic96-gs

Effectiveness of pulsed radio frequency in seed quality improvement of vegetable plant species

The biggest problem, in ecological vegetable seed production, is low germination mostly caused by high seed infection with fungi and a shortage of effective biological agents eliminating pathogens. Therefore, pro-ecological methods of seed quality enhancement are being searched, increasing the profitability of seed production by improving the seed sowing value. The aim of the work was to evaluate the effectiveness of pulsed radio frequency (PRF) on seed quality of selected vegetable cultivars. The obtained results from conducted research in laboratory, greenhouse and field conditions indicate a protective effect of PRF treatment by reduction of beetroot, lettuce and garden dill seed-borne fungi, and the improvement of their health status and seed germination. Pre-sowing application of PRF resulted in 60-80% reduction of seed infestation with fungi, depending on the plant species. This treatment improved the dynamics of seed germination, plant emergence, growth, and increased chlorophyll content and gas exchange in leaves. The most beneficial results were obtained in beetroot, in which the problem of seed production is associated with high seed infestation with mycoflora and the presence of germination inhibitors in the seed coat. The results indicate the high efficiency of the applied PRF and its usefulness in ecological and integrated seed production.Plant science

DOK2 inhibits EGFR-mutated lung adenocarcinoma

Somatic mutations in the EGFR proto-oncogene occur in ~15% of human lung adenocarcinomas and the importance of EGFR mutations for the initiation and maintenance of lung cancer is well established from mouse models and cancer therapy trials in human lung cancer patients. Recently, we identified DOK2 as a lung adenocarcinoma tumor suppressor gene. Here we show that genomic loss of DOK2 is associated with EGFR mutations in human lung adenocarcinoma, and we hypothesized that loss of DOK2 might therefore cooperate with EGFR mutations to promote lung tumorigenesis. We tested this hypothesis using genetically engineered mouse models and find that loss of Dok2 in the mouse accelerates lung tumorigenesis initiated by oncogenic EGFR, but not that initiated by mutated Kras. Moreover, we find that DOK2 participates in a negative feedback loop that opposes mutated EGFR; EGFR mutation leads to recruitment of DOK2 to EGFR and DOK2-mediated inhibition of downstream activation of RAS. These data identify DOK2 as a tumor suppressor in EGFR-mutant lung adenocarcinoma

\b{eta}-delayed three-proton decay of 31Ar

The beta decay of 31Ar, produced by fragmentation of a 36Ar beam at 880 MeV/nucleon, was investigated. Identified ions of 31Ar were stopped in a gaseous time projection chamber with optical readout allowing to record decay events with emission of protons. In addition to \b{eta}-delayed emission of one and two protons we have clearly observed the beta-delayed three-proton branch. The branching ratio for this channel in 31Ar is found to be 0.07(2)%.Comment: 5 pages, 3 figures, submitted to Physical Rev.

Proton Drip-Line Calculations and the Rp-process

One-proton and two-proton separation energies are calculated for proton-rich nuclei in the region $A=41-75$. The method is based on Skyrme Hartree-Fock calculations of Coulomb displacement energies of mirror nuclei in combination with the experimental masses of the neutron-rich nuclei. The implications for the proton drip line and the astrophysical rp-process are discussed. This is done within the framework of a detailed analysis of the sensitivity of rp process calculations in type I X-ray burst models on nuclear masses. We find that the remaining mass uncertainties, in particular for some nuclei with $N=Z$, still lead to large uncertainties in calculations of X-ray burst light curves. Further experimental or theoretical improvements of nuclear mass data are necessary before observed X-ray burst light curves can be used to obtain quantitative constraints on ignition conditions and neutron star properties. We identify a list of nuclei for which improved mass data would be most important.Comment: 20 pages, 9 figures, 2 table

Establishment and validation of cyberknife irradiation in a syngeneic glioblastoma mouse model

CyberKnife stereotactic radiosurgery (CK-SRS) precisely delivers radiation to intracranial tumors. However, the underlying radiobiological mechanisms at high single doses are not yet fully understood. Here, we established and evaluated the early radiobiological effects of CK-SRS treatment at a single dose of 20 Gy after 15 days of tumor growth in a syngeneic glioblastoma-mouse model. Exact positioning was ensured using a custom-made, non-invasive, and trackable frame. One superimposed target volume for the CK-SRS planning was created from the fused tumor volumes obtained from MRIs prior to irradiation. Dose calculation and delivery were planned using a single-reference CT scan. Six days after irradiation, tumor volumes were measured using MRI scans, and radiobiological effects were assessed using immunofluorescence staining. We found that CK-SRS treatment reduced tumor volume by approximately 75%, impaired cell proliferation, diminished tumor vasculature, and increased immune response. The accuracy of the delivered dose was demonstrated by staining of DNA double-strand breaks in accordance with the planned dose distribution. Overall, we confirmed that our proposed setup enables the precise irradiation of intracranial tumors in mice using only one reference CT and superimposed MRI volumes. Thus, our proposed mouse model for reproducible CK-SRS can be used to investigate radiobiological effects and develop novel therapeutic approaches