The Concept of Neuro-ophthalmology in the Context of Ayurveda

The academic specialization of neuro-ophthalmology combines the sciences of neurology and ophthalmology and frequently deals with complicated systemic disorders that appear in the visual system. Initially completing a residency in either neurology or ophthalmology, neuro-ophthalmologists then pursue a fellowship in a related specialty. A thorough medical history and physical examination are required and neuro-ophthalmologists frequently spend a lot of time with their patients because diagnostic tests can be normal in individuals with substantial neuro-ophthalmic disease1. Common pathology referred to a neuro-ophthalmologist includes afferent visual system disorders (e.g. optic neuritis, optic neuropathy, papilledema, brain tumors or strokes) and efferent visual system disorders (e.g. anisocoria, diplopia, ophthalmoplegia, ptosis, nystagmus, and blepharospas, seizures of the eye or eye muscles, and hemifacial spasm). The North American Neuro-Ophthalmological Society (NANOS) 2, which hosts an annual congress and disseminates the Journal of Neuro-Ophthalmology, is the biggest worldwide organization of neuro-ophthalmologists. Large university-based medical centers frequently employ neuro-ophthalmologists as faculty members. The neuro-ophthalmologist frequently serves as a liaison between the ophthalmology department and other departments at the medical Centre since patients frequently have co-existing disorders in other domains (rheumatology, endocrinology, cancer, cardiology, etc.)3. In Ayurveda concept of patala is very much required to understand the diseases of neuro ophthalmology. When vitiated dosha reaches at particular patala then particular symptom is seen. According to Susruta when vitiated doshas reaches in 1st, 2nd and 3rd patala it is known as Timir, vitiated doshas reaches in 3rd patala and ragata prapti occurs (pigmentation) it is known as Kacha. Vitiated doshas reaches in 4th patala it is known as Linganasha.According to Vagbhata, vitiated doshas reaches in 1st, 2nd patala it is known as Timir. vitiated doshas reaches in 2rd patala and ragata prapti occurs (pigmentation) it is known as Kacha vitiated doshas reaches in 4th patala it is known as Linganasha4. In this Review article we try to find out the co relation between different diseases in neuro ophthalmology and different Dristi gata roga

Geriatric prescription analysis with respect to “STOPP” and “START” criteria: a descriptive study in the Indian scenario

Background: Patients; sixty-five years of age and above, are a special risk group as far as drug prescribing is concerned. Prescription irregularities in such patients may be hazardous. STOPP/START criteria are considered as the most up to-date set of explicit criteria for evaluating geriatric prescriptions. To analyse geriatric prescriptions in a tertiary care centre with respect to STOPP/START criteria and WHO core drug prescribing indicators so as to get an idea of pattern of drug prescription in geriatric patients as well as frequency of potentially inappropriate prescriptions. Descriptive cross-sectional study in a tertiary care hospital.Methods: All inpatients aged 65 years and above who were prescribed at least one allopathic medication and consented to participate in the study were included and patients admitted for medical emergencies were excluded. Demographic data and details of drugs prescribed were collected from prescription chits and indoor case papers.Results: There was a high frequency of polypharmacy, prescription of antimicrobials and injections. Proportion of patients receiving at least one potentially inappropriate medication (PIM) as per STOPP criteria was 21.01%. Proportion of patients subjected to at least one potential prescribing omission (PPO) as per START criteria was 33.33%. Proportion of patients exposed to potentially inappropriate drug prescriptions as a whole (PIPs=PIMs+PPOs) was 46.37%. Statistical analysis used as descriptive statistics like numbers and percentages were used for data analysis.Conclusions: With regards to geriatric prescribing, adherence to WHO core prescribing indicators, prescription of drugs as per STOPP and START guidelines are indicative of scope for improvement

Cybersecurity 4.0: safeguarding trust and production in the digital food industry era

The food industry is vital manufacturing sector globally, with an ever-increasing reliance on digitalisation and technology-driven processes. However, this advancement introduces inherent cyberattack risks, encompassing data breaches and system disruptions, which can severely impact production and disrupt the entire food chain. Consequently, cyber threats can evoke fear and mistrust among consumers, potentially tarnishing a company's brand. This paper presents a comprehensive research methodology, including an extensive literature review and a detailed survey, aimed at assessing the current state of cybersecurity within the food industry. The problem at hand is the industry's apparent lack of robust cybersecurity measures to protect against the growing threat landscape, which this research aims to address. Our findings reveal a clear gap in cybersecurity preparedness within the food industry, with potential vulnerabilities that could be exploited by cyber adversaries. In response, we propose a specialised security framework designed to mitigate these risks. The framework is built upon a thorough analysis of the industry's existing cybersecurity posture and the identification of both current and emerging cyber threats. The contribution of this research relies in the development of a security framework that strengthens the industry's cyber defenses, thereby enhancing its competitive advantage. The framework emphasizes the importance of continuous employee education and training as a cornerstone for improving the security environment. Enhancing the security environment through ongoing employee education and training is crucial for fostering consumer trust and enabling seamless growth within the industry. By adopting a proactive approach to cybersecurity, the food industry can ensure the sustainability and reliability of its operations in the face of evolving cyber threats

Perspective Chapter: Dental Home – A Neglected Primary Oral Health Care Concept

Tooth decay, if left untreated even in the earliest stages of life, can have serious implications for a child’s long-term health and well-being. Early preventive care is a sound health and economic investment. Dental assessments and evaluations for children during their first year of life have been recommended by the American Academy of Pediatric Dentistry (AAPD) and the American Association of Pediatrics (ADA). Establishment of dental home and use of anticipatory guidance is one of the concepts in comprehensive oral health care. AAPD and ADA support the concept of a “dental home,” which is the ongoing relationship between the dentist and the patient. Establishing a dental home means that a child’s oral health care is managed in a comprehensive, continuously accessible, coordinated, and family-centered way by a licensed dentist. The dental professional’s ability to provide optimal oral health care, beginning from when the child is 1-year-old, dental visit leading to preventive care and treatment as part of an overall oral health care foundation for life, is enhanced by dental home. The establishment of the dental home also assures appropriate referral to dental specialists when availability of direct care is not possible within the dental home

Using an abdominal phantom to teach urology residents ultrasound-guided percutaneous needle placement

ABSTRACT Introduction: To assess the effect of a hands-on ultrasound training session to teach urologic trainees ultrasound-guided percutaneous needle placement. Materials and methods: University of California, San Francisco (UCSF) urology residents completed a time trial, placing a needle into a phantom model target under ultrasound guidance. Participants were randomized into three educational exposure groups: Group 1's time trial occurred prior to any teaching intervention, group 2's after experiencing a hands-on training module, and group 3's after exposure to both the training module and one-on-one attending feedback. Needle placement speed and accuracy as well as trainees' perceived confidence in utilizing ultrasound were measured. Results: The study cohort consisted of 15 resident trainees. Seven were randomized to group 1, three to group 2, and five to group 3. All residents reported minimal prior ultrasound experience. Their confidence in using ultrasound improved significantly after completing the training module with the most significant improvement seen among junior residents. Time to needle placement was fastest after receiving attending feedback (46.6sec in group 3 vs. 82.7sec in groups 1 and 2, p<0.01). Accuracy also improved with attending feedback, though the number of repositioning attempts did not differ significantly between groups. Conclusions: A hands-on training module and use of an abdominal phantom trainer increased resident confidence and skill in their use of ultrasound to guide percutaneous needle positioning. Attending feedback is critical for improving accuracy in needle guidance toward a target. Ultrasound-guided needle positioning is a teachable skill and can be applicable to multiple urologic procedures

Isolation and molecular characterization of dengue virus clinical isolates from pediatric patients in New Delhi

Objective: To characterize the in vitro replication fitness, viral diversity, and phylogeny of dengue viruses (DENV) isolated from Indian patients. Methods: DENV was isolated from whole blood collected from patients by passaging in cell culture. Passage 3 viruses were used for growth kinetics in C6/36 mosquito cells. Parallel efforts also focused on the isolation of DENV RNA from plasma samples of the same patients, which were processed for next-generation sequencing. Results: It was possible to isolate 64 clinical isolates of DENV, mostly DENV-2. Twenty-five of these were further used for growth curve analysis in vitro, which showed a wide range of replication kinetics. The highest viral titers were associated with isolates from patients with dengue with warning signs and severe dengue cases. Full genome sequences of 21 DENV isolates were obtained. Genome analysis mapped the circulating DENV-2 strains to the Cosmopolitan genotype. Conclusions: The replication kinetics of isolates from patients with mild or severe infection did not differ significantly, but the viral titers varied by two orders of magnitude between the isolates, suggesting differences in replication fitness among the circulating DENV-2