91 research outputs found
Quantum Cosmology of Kantowski-Sachs like Models
The Wheeler-DeWitt equation for a class of Kantowski-Sachs like models is
completely solved. The generalized models include the Kantowski-Sachs model
with cosmological constant and pressureless dust. Likewise contained is a
joined model which consists of a Kantowski-Sachs cylinder inserted between two
FRW half--spheres. The (second order) WKB approximation is exact for the wave
functions of the complete set and this facilitates the product structure of the
wave function for the joined model. In spite of the product structure the wave
function can not be interpreted as admitting no correlations between the
different regions. This problem is due to the joining procedure and may
therefore be present for all joined models. Finally, the {s}ymmetric {i}nitial
{c}ondition (SIC) for the wave function is analyzed and compared with the ``no
bouindary'' condition. The consequences of the different boundary conditions
for the arrow of time are briefly mentioned.Comment: 21 pages, uses LaTeX2e, epsf.sty and float.sty, three figures (50
kb); changes: one figure added, new interpretation of quantizing procedure
for the joined model and many minor change
Problem of Time in Quantum Gravity
The Problem of Time occurs because the `time' of GR and of ordinary Quantum
Theory are mutually incompatible notions. This is problematic in trying to
replace these two branches of physics with a single framework in situations in
which the conditions of both apply, e.g. in black holes or in the very early
universe. Emphasis in this Review is on the Problem of Time being multi-faceted
and on the nature of each of the eight principal facets. Namely, the Frozen
Formalism Problem, Configurational Relationalism Problem (formerly Sandwich
Problem), Foliation Dependence Problem, Constraint Closure Problem (formerly
Functional Evolution Problem), Multiple Choice Problem, Global Problem of Time,
Problem of Beables (alias Problem of Observables) and Spacetime
Reconstruction/Replacement Problem. Strategizing in this Review is not just
centred about the Frozen Formalism Problem facet, but rather about each of the
eight facets. Particular emphasis is placed upon A) relationalism as an
underpinning of the facets and as a selector of particular strategies
(especially a modification of Barbour relationalism, though also with some
consideration of Rovelli relationalism). B) Classifying approaches by the full
ordering in which they embrace constrain, quantize, find time/history and find
observables, rather than only by partial orderings such as "Dirac-quantize". C)
Foliation (in)dependence and Spacetime Reconstruction for a wide range of
physical theories, strategizing centred about the Problem of Beables, the
Patching Approach to the Global Problem of Time, and the role of the
question-types considered in physics. D) The Halliwell- and
Gambini-Porto-Pullin-type combined Strategies in the context of semiclassical
quantum cosmology.Comment: Invited Review: 26 pages including 2 Figures. This v2 has a number of
minor improvements and correction
Dirac's Observables for the Rest-Frame Instant Form of Tetrad Gravity in a Completely Fixed 3-Orthogonal Gauge
We define the {\it rest-frame instant form} of tetrad gravity restricted to
Christodoulou-Klainermann spacetimes. After a study of the Hamiltonian group of
gauge transformations generated by the 14 first class constraints of the
theory, we define and solve the multitemporal equations associated with the
rotation and space diffeomorphism constraints, finding how the cotriads and
their momenta depend on the corresponding gauge variables. This allows to find
quasi-Shanmugadhasan canonical transformation to the class of 3-orthogonal
gauges and to find the Dirac observables for superspace in these gauges.
The construction of the explicit form of the transformation and of the
solution of the rotation and supermomentum constraints is reduced to solve a
system of elliptic linear and quasi-linear partial differential equations. We
then show that the superhamiltonian constraint becomes the Lichnerowicz
equation for the conformal factor of the 3-metric and that the last gauge
variable is the momentum conjugated to the conformal factor. The gauge
transformations generated by the superhamiltonian constraint perform the
transitions among the allowed foliations of spacetime, so that the theory is
independent from its 3+1 splittings. In the special 3-orthogonal gauge defined
by the vanishing of the conformal factor momentum we determine the final Dirac
observables for the gravitational field even if we are not able to solve the
Lichnerowicz equation. The final Hamiltonian is the weak ADM energy restricted
to this completely fixed gauge.Comment: RevTeX file, 141 page
Emerging pharmacotherapy of tinnitus
Tinnitus, the perception of sound in the absence of an auditory stimulus, is perceived by about 1 in 10 adults, and for at least 1 in 100, tinnitus severely affects their quality of life. Because tinnitus is frequently associated with irritability, agitation, stress, insomnia, anxiety and depression, the social and economic burdens of tinnitus can be enormous. No curative treatments are available. However, tinnitus symptoms can be alleviated to some extent. The most widespread management therapies consist of auditory stimulation and cognitive behavioral treatment, aiming at improving habituation and coping strategies. Available clinical trials vary in methodological rigor and have been performed for a considerable number of different drugs. None of the investigated drugs have demonstrated providing replicable long-term reduction of tinnitus impact in the majority of patients in excess of placebo effects. Accordingly, there are no FDA or European Medicines Agency approved drugs for the treatment of tinnitus. However, in spite of the lack of evidence, a large variety of different compounds are prescribed off-label. Therefore, more effective pharmacotherapies for this huge and still growing market are desperately needed and even a drug that produces only a small but significant effect would have an enormous therapeutic impact. This review describes current and emerging pharmacotherapies with current difficulties and limitations. In addition, it provides an estimate of the tinnitus market. Finally, it describes recent advances in the tinnitus field which may help overcome obstacles faced in the pharmacological treatment of tinnitus. These include incomplete knowledge of tinnitus pathophysiology, lack of well-established animal models, heterogeneity of different forms of tinnitus, difficulties in tinnitus assessment and outcome measurement and variability in clinical trial methodology. © 2009 Informa UK Ltd.Fil: Langguth, Berthold. Universitat Regensburg; AlemaniaFil: Salvi, Richard. State University of New York; Estados UnidosFil: Elgoyhen, Ana Belen. Consejo Nacional de Investigaciones Científicas y Técnicas. Instituto de Investigaciones en Ingeniería Genética y Biología Molecular "Dr. Héctor N. Torres"; Argentin
Positive specific heat of the quantum corrected dilaton black hole
Path integral quantization of dilaton gravity in two dimensions is applied to
the CGHS model to the first nontrivial order in matter loops. Our approach is
background independent as geometry is integrated out exactly. The result is an
effective shift of the Killing norm: the apparent horizon becomes smaller. The
Hawking temperature which is constant to leading order receives a quantum
correction. As a consequence, the specific heat becomes positive and
proportional to the square of the black hole mass.Comment: 18 pages, JHEP style, 1 eps figure, v2: extended the discussion,
added new formulas for mass change, added three new references (in particular
[35]
The Bohm Interpretation of Quantum Cosmology
I make a review on the aplications of the Bohm-De Broglie interpretation of
quantum mechanics to quantum cosmology. In the framework of minisuperspaces
models, I show how quantum cosmological effects in Bohm's view can avoid the
initial singularity, isotropize the Universe, and even be a cause for the
present observed acceleration of the Universe. In the general case, we
enumerate the possible structures of quantum space and time.Comment: 28 pages, 1 figure, contribution to the James Cushing festschrift to
appear in Foundations of Physic
Long time black hole evaporation with bounded Hawking flux
The long time behavior of an evaporating Schwarzschild black hole is studied
exploiting that it can be described by an effective theory in 2D, a particular
dilaton gravity model.
A crucial technical ingredient is Izawa's result on consistent deformations
of 2D BF theory, while the most relevant physical assumption is boundedness of
the asymptotic matter flux during the whole evaporation process.
An attractor solution, the endpoint of the evaporation process, is found. Its
metric is flat. However, the behavior of the dilaton field is nontrivial: it is
argued that during the final flicker a first order phase transition occurs from
a linear to a constant dilaton vacuum, thereby emitting a shock wave with a
total energy of a fraction of the Planck mass. Another fraction of the Planck
mass may reside in a cold remnant. [Note: More detailed abstract in the paper]Comment: 34 pages, 6 figures, v2: included new references and 2 new footnotes;
v3: mayor revisions (extended intro, included pedagogical example, rearranged
presentation, extended discussion on information paradox, updated
references); v4: updated refs. (+ new ones), added comments, mostly on
dilaton evaporation, rewrote abstract (short for arXiv, long for journal),
moved pedagogic sec. to ap
Clusters of galaxies : observational properties of the diffuse radio emission
Clusters of galaxies, as the largest virialized systems in the Universe, are
ideal laboratories to study the formation and evolution of cosmic
structures...(abridged)... Most of the detailed knowledge of galaxy clusters
has been obtained in recent years from the study of ICM through X-ray
Astronomy. At the same time, radio observations have proved that the ICM is
mixed with non-thermal components, i.e. highly relativistic particles and
large-scale magnetic fields, detected through their synchrotron emission. The
knowledge of the properties of these non-thermal ICM components has increased
significantly, owing to sensitive radio images and to the development of
theoretical models. Diffuse synchrotron radio emission in the central and
peripheral cluster regions has been found in many clusters. Moreover
large-scale magnetic fields appear to be present in all galaxy clusters, as
derived from Rotation Measure (RM) studies. Non-thermal components are linked
to the cluster X-ray properties, and to the cluster evolutionary stage, and are
crucial for a comprehensive physical description of the intracluster medium.
They play an important role in the cluster formation and evolution. We review
here the observational properties of diffuse non-thermal sources detected in
galaxy clusters: halos, relics and mini-halos. We discuss their classification
and properties. We report published results up to date and obtain and discuss
statistical properties. We present the properties of large-scale magnetic
fields in clusters and in even larger structures: filaments connecting galaxy
clusters. We summarize the current models of the origin of these cluster
components, and outline the improvements that are expected in this area from
future developments thanks to the new generation of radio telescopes.Comment: Accepted for the publication in The Astronomy and Astrophysics
Review. 58 pages, 26 figure
The Science of Sungrazers, Sunskirters, and Other Near-Sun Comets
This review addresses our current understanding of comets that venture close to the Sun, and are hence exposed to much more extreme conditions than comets that are typically studied from Earth. The extreme solar heating and plasma environments that these objects encounter change many aspects of their behaviour, thus yielding valuable information on both the comets themselves that complements other data we have on primitive solar system bodies, as well as on the near-solar environment which they traverse. We propose clear definitions for these comets: We use the term near-Sun comets to encompass all objects that pass sunward of the perihelion distance of planet Mercury (0.307 AU). Sunskirters are defined as objects that pass within 33 solar radii of the Sun’s centre, equal to half of Mercury’s perihelion distance, and the commonly-used phrase sungrazers to be objects that reach perihelion within 3.45 solar radii, i.e. the fluid Roche limit. Finally, comets with orbits that intersect the solar photosphere are termed sundivers. We summarize past studies of these objects, as well as the instruments and facilities used to study them, including space-based platforms that have led to a recent revolution in the quantity and quality of relevant observations. Relevant comet populations are described, including the Kreutz, Marsden, Kracht, and Meyer groups, near-Sun asteroids, and a brief discussion of their origins. The importance of light curves and the clues they provide on cometary composition are emphasized, together with what information has been gleaned about nucleus parameters, including the sizes and masses of objects and their families, and their tensile strengths. The physical processes occurring at these objects are considered in some detail, including the disruption of nuclei, sublimation, and ionisation, and we consider the mass, momentum, and energy loss of comets in the corona and those that venture to lower altitudes. The different components of comae and tails are described, including dust, neutral and ionised gases, their chemical reactions, and their contributions to the near-Sun environment. Comet-solar wind interactions are discussed, including the use of comets as probes of solar wind and coronal conditions in their vicinities. We address the relevance of work on comets near the Sun to similar objects orbiting other stars, and conclude with a discussion of future directions for the field and the planned ground- and space-based facilities that will allow us to address those science topics
Influence of a montmorency cherry juice blend on indices of exercise-induced stress and upper respiratory tract symptoms following marathon running—a pilot investigation
Background: Prolonged exercise, such as marathon running, has been associated with an increase in respiratory mucosal inflammation. The aim of this pilot study was to examine the effects of Montmorency cherry juice on markers of stress, immunity and inflammation following a Marathon.
Methods: Twenty recreational Marathon runners consumed either cherry juice (CJ) or placebo (PL) before and after a Marathon race. Markers of mucosal immunity secretory immunoglobulin A (sIgA), immunoglobulin G (IgG), salivary cortisol, inflammation (CRP) and self-reported incidence and severity of upper respiratory tract symptoms (URTS) were measured before and following the race.
Results: All variables except secretory IgA and IgG concentrations in saliva showed a significant time effect (P < 0.01). Serum CRP showed a significant interaction and treatment effect (P < 0.01). The CRP increase at 24 and 48 h post-Marathon was lower (P < 0.01) in the CJ group compared to PL group. Mucosal immunity and salivary cortisol showed no interaction effect or treatment effect. The incidence and severity of URTS was significantly greater than baseline at 24 h and 48 h following the race in the PL group and was also greater than the CJ group (P < 0.05). No URTS were reported in the CJ group whereas 50 % of runners in the PL group reported URTS at 24 h and 48 h post-Marathon.
Conclusions: This is the first study that provides encouraging evidence of the potential role of Montmorency cherries in reducing the development of URTS post-Marathon possibly caused by exercise-induced hyperventilation trauma, and/or other infectious and non-infectious factors
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