1,212 research outputs found
Qualidade dos menus infantis em shoppings centers do Brasil
Resumo Objetivos: caracterizar a disponibilidade e a qualidade nutricional dos menus infantis nos restaurantes e estabelecimentos de fast-foods em Shoppings Centers no Brasil. MĂ©todos: trata-se de um estudo observacional e transversal. Os dados foram coletados nos websites de cada estabelecimento e em aplicativos de vendas de alimentos, com questionário composto por duas seções: Caracterização do estabelecimento e caracterização do menu infantil. A coleta dos dados ocorreu em dez capitais distribuĂdas nas cinco regiões do Brasil. Resultados: foram avaliados 116 menus infantis. Maior nĂşmero de estabelecimentos foi classifcado como restaurante do que fast-food. Os mĂ©todos de cocção mais utilizados nos pratos principais foram grelhados (n=236, 64%) e cozidos (n=74, 20%), e nos acompanhamentos foram cozidos (n=204, 53%) e fritos (n=109, 28%). Apenas 40% (n=46) dos menus continham hortaliças. Menos de 10% (n=sete) ofertavam fruta como sobremesa; 31% (n=36) constavam bebida inclusa no menu infantil; 22% (n=25) ofereciam brindes associados ao menu. Apenas 32 (28%) estabelecimentos apresentavam a combinação feijĂŁo e arroz. ConclusĂŁo: a maioria das opções ofertadas Ă s crianças era de baixa qualidade nutricional, com pouca oferta de hortaliças, frutas e do tradicional feijĂŁo e arroz. As bebidas incluĂdas nos menus, a maioria açucaradas, podem contribuir para uma elevada ingestĂŁo energĂ©tica. Constata-se a necessidade de disponibilizar opções saudáveis e incentivar essas escolhas.</jats:p
Impact of splenic artery ligation after major hepatectomy on liver function, regeneration and viability
It was reported that prevention of acute portal overpressure in small-for-size livers by inflow modulation results in a better postoperative outcome. The aim is to investigate the impact of portal blood flow reduction by splenic artery ligation after major hepatectomy in a murine model. Forty-eight rats were subjected to an 85% hepatectomy or 85% hepatectomy and splenic artery ligation. Both groups were evaluated at 24, 48, 72 and 120 post-operative hours: liver function, regeneration and viability. All methods and experiments were carried out in accordance with Coimbra University guidelines. Splenic artery ligation produces viability increase after 24 h, induces a relative decrease in oxidative stress during the first 48 hours, allows antioxidant capacity increment after 24 h, which is reflected in a decrease of half-time normalized liver curve at 48 h and at 72 h and in an increase of mitotic index between 48 h and 72 h. Splenic artery ligation combined with 85% hepatectomy in a murine model, allows portal inflow modulation, promoting an increase in hepatocellular viability and regeneration, without impairing the function, probably by inducing a less marked elevation of oxidative stress at first 48 hours
Strength training to prevent falls in older adults: A systematic review with meta-analysis of randomized controlled trials
We performed a systematic review with meta-analysis of randomized controlled trials (RCTs) to assess the effects of strength training (ST), as compared to alternative multimodal or unimodal exercise programs, on the number of falls in older adults (=60 years). Ten databases were consulted (CINAHL, Cochrane Library, EBSCO, EMBASE, PEDro, PubMed, Scielo, Scopus, SPORTDiscus and Web of Science), without limitations on language or publication date. Eligibility criteria were as follows: RCTs with humans =60 years of age of any gender with one group performing supervised ST and a group performing another type of exercise training, reporting data pertaining falls. Certainty of evidence was assessed with Grading of Recommendations, Assessment, Development and Evaluation (GRADE). Meta-analysis used a random effects model to calculate the risk ratio (RR) for number of falls. Five RCTs with six trials were included (n = 543, 76% women). There was no difference between ST and alternative exercise interventions for falls (RR = 1.00, 95% CI 0.77–1.30, p = 0.99). The certainty of evidence was very low. No dose–response relationship could be established. In sum, ST showed comparable RR based on number of falls in older adults when compared to other multimodal or unimodal exercise modalities, but evidence is scarce and heteroge-neous, and additional research is required for more robust conclusions. Registration: PROSPERO CRD42020222908
Random Walks on Stochastic Temporal Networks
In the study of dynamical processes on networks, there has been intense focus
on network structure -- i.e., the arrangement of edges and their associated
weights -- but the effects of the temporal patterns of edges remains poorly
understood. In this chapter, we develop a mathematical framework for random
walks on temporal networks using an approach that provides a compromise between
abstract but unrealistic models and data-driven but non-mathematical
approaches. To do this, we introduce a stochastic model for temporal networks
in which we summarize the temporal and structural organization of a system
using a matrix of waiting-time distributions. We show that random walks on
stochastic temporal networks can be described exactly by an
integro-differential master equation and derive an analytical expression for
its asymptotic steady state. We also discuss how our work might be useful to
help build centrality measures for temporal networks.Comment: Chapter in Temporal Networks (Petter Holme and Jari Saramaki
editors). Springer. Berlin, Heidelberg 2013. The book chapter contains minor
corrections and modifications. This chapter is based on arXiv:1112.3324,
which contains additional calculations and numerical simulation
High prevalence of Trichomonas gallinae in wild columbids across western and southern Europe
Avian trichomonosis is known as a widespread disease in columbids and passerines, and recent findings have highlighted the pathogenic character of some lineages found in wild birds. Trichomonosis can affect wild bird populations including endangered species, as has been shown for Mauritian pink pigeons Nesoenas mayeri in Mauritius and suggested for European turtle doves Streptopelia turtur in the UK. However, the disease trichomonosis is caused only by pathogenic lineages of the parasite Trichomonas gallinae. Therefore, understanding the prevalence and distribution of both potentially pathogenic and non-pathogenic T. gallinae lineages in turtle doves and other columbids across Europe is relevant to estimate the potential impact of the disease on a continental scale
Interstellar Turbulence II: Implications and Effects
Interstellar turbulence has implications for the dispersal and mixing of the
elements, cloud chemistry, cosmic ray scattering, and radio wave propagation
through the ionized medium. This review discusses the observations and theory
of these effects. Metallicity fluctuations are summarized, and the theory of
turbulent transport of passive tracers is reviewed. Modeling methods, turbulent
concentration of dust grains, and the turbulent washout of radial abundance
gradients are discussed. Interstellar chemistry is affected by turbulent
transport of various species between environments with different physical
properties and by turbulent heating in shocks, vortical dissipation regions,
and local regions of enhanced ambipolar diffusion. Cosmic rays are scattered
and accelerated in turbulent magnetic waves and shocks, and they generate
turbulence on the scale of their gyroradii. Radio wave scintillation is an
important diagnostic for small scale turbulence in the ionized medium, giving
information about the power spectrum and amplitude of fluctuations. The theory
of diffraction and refraction is reviewed, as are the main observations and
scintillation regions.Comment: 46 pages, 2 figures, submitted to Annual Reviews of Astronomy and
Astrophysic
Two chemically similar stellar overdensities on opposite sides of the plane of the Galaxy
Our Galaxy is thought to have undergone an active evolutionary history
dominated by star formation, the accretion of cold gas, and, in particular,
mergers up to 10 gigayear ago. The stellar halo reveals rich fossil evidence of
these interactions in the form of stellar streams, substructures, and
chemically distinct stellar components. The impact of dwarf galaxy mergers on
the content and morphology of the Galactic disk is still being explored. Recent
studies have identified kinematically distinct stellar substructures and moving
groups, which may have extragalactic origin. However, there is mounting
evidence that stellar overdensities at the outer disk/halo interface could have
been caused by the interaction of a dwarf galaxy with the disk. Here we report
detailed spectroscopic analysis of 14 stars drawn from two stellar
overdensities, each lying about 5 kiloparsecs above and below the Galactic
plane - locations suggestive of association with the stellar halo. However, we
find that the chemical compositions of these stars are almost identical, both
within and between these groups, and closely match the abundance patterns of
the Milky Way disk stars. This study hence provides compelling evidence that
these stars originate from the disk and the overdensities they are part of were
created by tidal interactions of the disk with passing or merging dwarf
galaxies.Comment: accepted for publication in Natur
Conditions for the Evolution of Gene Clusters in Bacterial Genomes
Genes encoding proteins in a common pathway are often found near each other along bacterial chromosomes. Several explanations have been proposed to account for the evolution of these structures. For instance, natural selection may directly favour gene clusters through a variety of mechanisms, such as increased efficiency of coregulation. An alternative and controversial hypothesis is the selfish operon model, which asserts that clustered arrangements of genes are more easily transferred to other species, thus improving the prospects for survival of the cluster. According to another hypothesis (the persistence model), genes that are in close proximity are less likely to be disrupted by deletions. Here we develop computational models to study the conditions under which gene clusters can evolve and persist. First, we examine the selfish operon model by re-implementing the simulation and running it under a wide range of conditions. Second, we introduce and study a Moran process in which there is natural selection for gene clustering and rearrangement occurs by genome inversion events. Finally, we develop and study a model that includes selection and inversion, which tracks the occurrence and fixation of rearrangements. Surprisingly, gene clusters fail to evolve under a wide range of conditions. Factors that promote the evolution of gene clusters include a low number of genes in the pathway, a high population size, and in the case of the selfish operon model, a high horizontal transfer rate. The computational analysis here has shown that the evolution of gene clusters can occur under both direct and indirect selection as long as certain conditions hold. Under these conditions the selfish operon model is still viable as an explanation for the evolution of gene clusters
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