Electronic structure in underdoped cuprates due to the emergence of a pseudogap

The phenomenological Green's function developed in the works of Yang, Rice and Zhang has been very successful in understanding many of the anomalous superconducting properties of the deeply underdoped cuprates. It is based on considerations of the resonating valence bond spin liquid approximation and is designed to describe the underdoped regime of the cuprates. Here we emphasize the region of doping, $x$, just below the quantum critical point at which the pseudogap develops. In addition to Luttinger hole pockets centered around the nodal direction, there are electron pockets near the antinodes which are connected to the hole pockets by gapped bridging contours. We determine the contours of nearest approach as would be measured in angular resolved photoemission experiments and emphasize signatures of the Fermi surface reconstruction from the large Fermi contour of Fermi liquid theory (which contains $1+x$ hole states) to the Luttinger pocket (which contains $x$ hole states). We find that the quasiparticle effective mass renormalization increases strongly towards the edge of the Luttinger pockets beyond which it diverges.Comment: 11 pages, 9 figure

Genome-wide association study identifies 30 Loci Associated with Bipolar Disorder

This paper is dedicated to the memory of Psychiatric Genomics Consortium (PGC) founding member and Bipolar disorder working group co-chair Pamela Sklar. We thank the participants who donated their time, experiences and DNA to this research, and to the clinical and scientific teams that worked with them. We are deeply indebted to the investigators who comprise the PGC. The views expressed are those of the authors and not necessarily those of any funding or regulatory body. Analyses were carried out on the NL Genetic Cluster Computer (http://www.geneticcluster.org ) hosted by SURFsara, and the Mount Sinai high performance computing cluster (http://hpc.mssm.edu).Bipolar disorder is a highly heritable psychiatric disorder. We performed a genome-wide association study including 20,352 cases and 31,358 controls of European descent, with follow-up analysis of 822 variants with P<1x10-4 in an additional 9,412 cases and 137,760 controls. Eight of the 19 variants that were genome-wide significant (GWS, p < 5x10-8) in the discovery GWAS were not GWS in the combined analysis, consistent with small effect sizes and limited power but also with genetic heterogeneity. In the combined analysis 30 loci were GWS including 20 novel loci. The significant loci contain genes encoding ion channels, neurotransmitter transporters and synaptic components. Pathway analysis revealed nine significantly enriched gene-sets including regulation of insulin secretion and endocannabinoid signaling. BDI is strongly genetically correlated with schizophrenia, driven by psychosis, whereas BDII is more strongly correlated with major depressive disorder. These findings address key clinical questions and provide potential new biological mechanisms for BD.This work was funded in part by the Brain and Behavior Research Foundation, Stanley Medical Research Institute, University of Michigan, Pritzker Neuropsychiatric Disorders Research Fund L.L.C., Marriot Foundation and the Mayo Clinic Center for Individualized Medicine, the NIMH Intramural Research Program; Canadian Institutes of Health Research; the UK Maudsley NHS Foundation Trust, NIHR, NRS, MRC, Wellcome Trust; European Research Council; German Ministry for Education and Research, German Research Foundation IZKF of Münster, Deutsche Forschungsgemeinschaft, ImmunoSensation, the Dr. Lisa-Oehler Foundation, University of Bonn; the Swiss National Science Foundation; French Foundation FondaMental and ANR; Spanish Ministerio de Economía, CIBERSAM, Industria y Competitividad, European Regional Development Fund (ERDF), Generalitat de Catalunya, EU Horizon 2020 Research and Innovation Programme; BBMRI-NL; South-East Norway Regional Health Authority and Mrs. Throne-Holst; Swedish Research Council, Stockholm County Council, Söderström Foundation; Lundbeck Foundation, Aarhus University; Australia NHMRC, NSW Ministry of Health, Janette M O'Neil and Betty C Lynch

Validation of ACE-FTS version 3.5 NO<i>y</i> species profiles using correlative satellite measurements

The ACE-FTS (Atmospheric Chemistry Experiment-Fourier Transform Spectrometer) instrument on the Canadian SCISAT satellite, which has been in operation for over 12 years, has the capability of deriving stratospheric profiles of many of the NO (N+NO+NO+NO+2×NO+HNO+HNO+ClONO+BrONO) species. Version 2.2 of ACE-FTS NO, NO, HNO, NO, and ClONO has previously been validated, and this study compares the most recent version (v3.5) of these five ACE-FTS products to spatially and temporally coincident measurements from other satellite instruments-GOMOS, HALOE, MAESTRO, MIPAS, MLS, OSIRIS, POAM III, SAGE III, SCIAMACHY, SMILES, and SMR. For each ACE-FTS measurement, a photochemical box model was used to simulate the diurnal variations of the NOy species and the ACE-FTS measurements were scaled to the local times of the coincident measurements. The comparisons for all five species show good agreement with correlative satellite measurements. For NO in the altitude range of 25-50 km, ACE-FTS typically agrees with correlative data to within .10 %. Instrumentaveraged mean relative differences are approximately.10% at 30-40 km for NO, within-7% at 8-30 km for HNO, better than.7% at 21-34 km for local morning NO, and better than.8% at 21-34 km for ClONO. Where possible, the variations in the mean differences due to changes in the comparison local time and latitude are also discussed.©2016 Author(s).The Atmospheric Chemistry Experiment is a Canadian-led mission mainly supported by the CSA. Odin is a Swedish-led satellite project funded jointly by Sweden (Swedish National Space Board), Canada (CSA), France (Centre National d'Etudes Spatiales), and Finland (Tekes), with support by the third-party mission programme of the European Space Agency (ESA). Coauthor CER was funded by NASA grant NNX14AH54G. The University of Bremen team was funded in parts by the DLR Space Agency (Germany) and by the University and State of Bremen.Peer Reviewe