Risk profiles and one-year outcomes of patients with newly diagnosed atrial fibrillation in India: Insights from the GARFIELD-AF Registry.

BACKGROUND: The Global Anticoagulant Registry in the FIELD-Atrial Fibrillation (GARFIELD-AF) is an ongoing prospective noninterventional registry, which is providing important information on the baseline characteristics, treatment patterns, and 1-year outcomes in patients with newly diagnosed non-valvular atrial fibrillation (NVAF). This report describes data from Indian patients recruited in this registry. METHODS AND RESULTS: A total of 52,014 patients with newly diagnosed AF were enrolled globally; of these, 1388 patients were recruited from 26 sites within India (2012-2016). In India, the mean age was 65.8 years at diagnosis of NVAF. Hypertension was the most prevalent risk factor for AF, present in 68.5% of patients from India and in 76.3% of patients globally (P < 0.001). Diabetes and coronary artery disease (CAD) were prevalent in 36.2% and 28.1% of patients as compared with global prevalence of 22.2% and 21.6%, respectively (P < 0.001 for both). Antiplatelet therapy was the most common antithrombotic treatment in India. With increasing stroke risk, however, patients were more likely to receive oral anticoagulant therapy [mainly vitamin K antagonist (VKA)], but average international normalized ratio (INR) was lower among Indian patients [median INR value 1.6 (interquartile range {IQR}: 1.3-2.3) versus 2.3 (IQR 1.8-2.8) (P < 0.001)]. Compared with other countries, patients from India had markedly higher rates of all-cause mortality [7.68 per 100 person-years (95% confidence interval 6.32-9.35) vs 4.34 (4.16-4.53), P < 0.0001], while rates of stroke/systemic embolism and major bleeding were lower after 1 year of follow-up. CONCLUSION: Compared to previously published registries from India, the GARFIELD-AF registry describes clinical profiles and outcomes in Indian patients with AF of a different etiology. The registry data show that compared to the rest of the world, Indian AF patients are younger in age and have more diabetes and CAD. Patients with a higher stroke risk are more likely to receive anticoagulation therapy with VKA but are underdosed compared with the global average in the GARFIELD-AF. CLINICAL TRIAL REGISTRATION-URL: http://www.clinicaltrials.gov. Unique identifier: NCT01090362

Body image and eating disorders [Imagen Corporal y Trastornos de la Conducta Alimentaria]

Objective Assessing the association of age and weight with internalisation of the ideal of being thin, bodily dissatisfaction and eating disorder symptoms amongst three groups of females: teenage, young and adult women. Material and Methods 145 females participated, ranging in age from 12 to 46, who answered four self-reporting questionnaires aimed at measuring symptoms of anorexia nervosa, bulimia nervosa, the ideal of being thin and bodily dissatisfaction. The participants' weight and height were also recorded for calculating their body mass index. Data analysis included descriptive and inferential statistics, specifically Spearman correlation and Kruskal-Wallis test. Results Being an older woman was associated with high internalisation of ideally being thin and bodily dissatisfaction; however, it was not correlated with eating disorder symptoms. Comparisons between groups showed that adult females were more dissatisfied with their bodies and their attitudes towards being thin; however, their attitudes and behaviour concerning abnormal eating were just as inappropriate as that amongst teenagers. Conclusions These findings show the need for research into attitudes towards eating amongst adult women because they use extreme methods for controlling weight which may result in higher health risks

Psychometric properties of the Drive for Muscularity Scale in Mexican males

This study refers to the evaluation of the psychometric properties of the Drive for Muscularity Scale among Mexican population. The exploratory factor analysis was carried out with 369 university males (mean age = 20.93 years). A three-factor structure that explains 45.64 % of the variance was found for the scale: 31.10 % by attitudes (α = 0.87), 10.70 % by substance intake (α = 0.72) and 3.84 % by training adherence (α = 0.68). Only the two first sub-scales and total score (α = 0.86) offered acceptable levels of internal consistence. The confirmatory factor analysis, carried out with 200 males (mean age = 20.79 years), verified both the suitability of this factor structure and the two-factor structure proposed by McCreary et al. (Psychol Men Masc 5:49-58, 1). Drive for muscularity is important in comprehending male body image and Drive for Muscularity Scale has demonstrated to be psychometrically suitable to assess this construct in Mexican males. © 2013 Springer International Publishing Switzerland

Body dissatisfaction and socio-cultural factors in women with and without BED: Their relation with eating psychopathology

The goal of the present study was to assess the role of body dissatisfaction and socio-cultural factors on eating psychopathology in women with Binge Eating Disorder (BED) and women without BED. Seventy obese women consecutively evaluated participated: 35 with BED and 35 without BED who attended for the first time in a weight loss program. All participants completed a battery of questionnaires, including: Body Shape Questionnaire, Questionnaire of Influences on the Aesthetic Body Shape Model, Questionnaire on Eating and Weight Patterns, Three Factor Eating Questionnaire, and they were interviewed with the Interview for the Diagnosis of Eating Disorder-IV. The Body Mass Index, Waist-to-Hip Ratio and Body Fat were calculated. The results showed that 21% of obese women who participated in a weight reduction program met BED criteria. The scores of body dissatisfaction, influences of socio-cultural factors and eating psychopathology were higher in women with BED compared with women without BED. In the same way, significantly stronger correlations were found among influences of socio-cultural factors, specifically, influence of advertisement, social relations and eating psychopathology in women with BED than women without BED. It is concluded that the high body dissatisfaction as well as stronger associations among influence of socio-cultural factors and eating psychopathology could play an important role in women with BED. �2012, Editrice Kurtis

Автоматизация бизнес-процессов компании «ВКМ-Сервис» на платформе 1С Предприятие 8.2

Целью работы является автоматизация экономических, бухгалтерских процессов компании «ВКМ-Сервис», представляющая собой собой оптимизацию расходования полезного времени работников, увеличение числа задач, решаемых программным образом, уменьшение влияния человеческого фактора

Introducing the CTA concept

The Cherenkov Telescope Array (CTA) is a new observatory for very high-energy (VHE) gamma rays. CTA has ambitions science goals, for which it is necessary to achieve full-sky coverage, to improve the sensitivity by about an order of magnitude, to span about four decades of energy, from a few tens of GeV to above 100 TeV with enhanced angular and energy resolutions over existing VHE gamma-ray observatories. An international collaboration has formed with more than 1000 members from 27 countries in Europe, Asia, Africa and North and South America. In 2010 the CTA Consortium completed a Design Study and started a three-year Preparatory Phase which leads to production readiness of CTA in 2014. In this paper we introduce the science goals and the concept of CTA, and provide an overview of the project. © 2013 Elsevier B.V. All rights reserved