The burden of disease in Spain: results from the global burden of disease study 2010

BackgroundWe herein evaluate the Spanish population¿s trends in health burden by comparing results of two Global Burden of Diseases, Injuries, and Risk Factors Studies (the GBD studies) performed 20 years apart.MethodsData is part of the GBD study for 1990 and 2010. We present results for mortality, years of life lost (YLLs), years lived with disability, and disability-adjusted life years (DALYs) for the Spanish population. Uncertainty intervals for all measures have been estimated.ResultsNon-communicable diseases accounted for 3,703,400 (95% CI 3,648,270¿3,766,720) (91.3%) of 4,057,400 total deaths, in the Spanish population. Cardiovascular and circulatory diseases were the main cause of mortality among non-communicable diseases (34.7% of total deaths), followed by neoplasms (27.1% of total deaths). Neoplasms, cardiovascular and circulatory diseases, and chronic respiratory diseases were the top three leading causes for YLLs. The most important causes of DALYs in 2010 were neoplasms, cardiovascular and circulatory diseases, musculoskeletal disorders, and mental and behavioral disorders.ConclusionsMortality and disability in Spain have become even more linked to non-communicable diseases over the last years, following the worldwide trends. Cardiovascular and circulatory diseases, neoplasms, mental and behavioral disorders, and neurological disorders are the leading causes of mortality and disability. Specific focus is needed from health care providers and policy makers to develop health promotion and health education programs directed towards non-communicable disorders

Rings and spirals in barred galaxies. III. Further comparisons and links to observations

In a series of papers, we propose a theory to explain the formation and properties of rings and spirals in barred galaxies. The building blocks of these structures are orbits guided by the manifolds emanating from the unstable Lagrangian points located near the ends of the bar. In this paper, the last of the series, we present more comparisons of our theoretical results to observations and also give new predictions for further comparisons. Our theory provides the right building blocks for the rectangular-like bar outline and for ansae. We consider how our results can be used to give estimates for the pattern speed values, as well as their effect on abundance gradients in barred galaxies. We present the kinematics along the manifold loci, to allow comparisons with the observed kinematics along the ring and spiral loci. We consider gaseous arms and their relations to stellar ones. We discuss several theoretical aspects and stress that the orbits that constitute the building blocks of the spirals and rings are chaotic. They are, nevertheless, spatially well confined by the manifolds and are thus able to outline the relevant structures. Such chaos can be termed `confined chaos' and can play a very important role in understanding the formation and evolution of galaxy structures and in galactic dynamics in general. This work, in agreement with several others, argues convincingly that galactic dynamic studies should not be limited to the study of regular motions and orbits.Comment: 17 pages, 12 figures; accepted in MNRA

Body piercing and tattoos: a survey on young adults' knowledge of the risks and practices in body art

<p>Abstract</p> <p>Background</p> <p>The practice of tattooing and piercing has expanded in western society. In order to verify young adults' knowledge of the risk and practices related to body art, an investigation was conducted among freshmen of the University of Bari in the region of Apulia, Italy.</p> <p>Methods</p> <p>The study was carried out in the Academic Year 2009-2010 through an anonymous self-administered written questionnaire distributed to 1.656 freshmen enrolled in 17 Degree Courses.</p> <p>Results</p> <p>Of the 1.598 students included in the analysis, 78.3% believe it is risky to undergo piercing/tattoo practices. AIDS was indicated as a possible infection by 60.3% of freshmen, hepatitis C by 38.2%, tetanus by 34.3% and hepatitis B by 33.7% of the sample. 28.1% of freshmen were not aware that there are also non-infectious complications. 29% of the sample had at least one piercing or tattoo (this percentage does not include earlobe piercing in women). Of those with body art, the decision to undergo body art was made autonomously in 57.9% of the participants. 56.3% of freshmen undergoing body art had taken less than a month to decide. With regard to the reasons that led the sample to undergo body art, 28.4% were unable to explain it, 23.8% answered to improve their aesthetic aspect, 18.4% to distinguish themselves from others, 12.3% for fashion; 17.1% for other reasons. 25.4% of the sample declared that they had a piercing (79.8% female vs 20.2% male; ratio M/F 1:4.0). The average age for a first piercing was 15.3 years (range 10-27; SD ± 2.9). 9.6% of the sample declared that they have a tattoo (69.9% female vs 30.1% male; ratio M/F 1:2.3). The average age for a first tattoo was 17.5 years (range 10-26, SD ± 2.4).</p> <p>Conclusions</p> <p>Most of the freshmen knew about AIDS-related risks but not other potential risks. Body art is fairly common among young adults (especially women). The decision is often not shared with the family and is undertaken mostly without a specific reason or for the improvement of aesthetic aspect. Information about freshmen's knowledge, attitudes and practices could help in effective planning of health promotion strategies.</p

Joint stakeholder decision-making on the management of the Silao-Romita aquifer using AHP

Over-exploitation and pollution have been identified as the main problems facing the Silao-Romita aquifer in Guanajuato, Mexico. The objective of this paper is to analyze the current situation, characterized by a clear lack of legislative enforcement, dispersion of competences, and scarcity of economic resources, in order to establish a new prioritization of action plans, and choose from among three specific management options. One of the main challenges when addressing these problems in a holistic manner is the conflicting viewpoints of the sectors involved. As each stakeholder has a different perception, there is a clear need for appropriate mechanisms to reach a consensus in decision-making. To achieve the objective, we use the Analytic Hierarchy Process (AHP), because of its flexibility and the availability of mathematical axiomatic principles and techniques to obtain group preferences and priorities. In addition, we use several tools developed by the authors to obtain consistency, streamline the trade-off between stakeholder know-how and synthetic consistency, and consistently complete partial judgments given by some of the stakeholders. The problem of obtaining a consensus among the actors involved regarding criteria and alternatives is also considered. The obtained results are intended to serve as guidelines for conducting priority actions to help solve the general problem of the study area, and to identify the management model that best meets the needs of the aquifer, according to the actors involved. (C) 2013 Elsevier Ltd. All rights reserved.This work has been supported by project IDAWAS, DPI2009-11591 of the Spanish Ministry of Science and Innovation; with supplementary support from ACOMP/2011/188 of the education department of the Generalitat Valenciana. The first author wishes to thank CONACYT for the 10007-2011-01 scholarship program. The use of English in this paper was revised by John Rawlins.Delgado Galván, XV.; Izquierdo Sebastián, J.; Benítez López, J.; Pérez García, R. (2014). Joint stakeholder decision-making on the management of the Silao-Romita aquifer using AHP. Environmental Modelling & Software. 51:310-322. https://doi.org/10.1016/j.envsoft.2013.10.008S3103225

Growth and water relations of field-grown Valencia orange trees under long-term partial rootzone drying

Climate, soil water potential (SWP), leaf relative water content (RWC), stem water potential (WPstem), stomatal conductance (gs), trunk, shoot and fruit growth of 'Valencia' orange trees were monitored during five consecutive seasons (2007â2012) to study water status and growth responses to irrigation placement or volume. 48 adult trees were exposed to conventional irrigation (CI, 100% of crop evapotranspiration on both sides of the rootzone), partial rootzone drying (PRD, 50% of CI water only on one alternated side of the rootzone) and continuous deficit irrigation (DI, 50% of CI water on both sides of the rootzone). Reducing irrigation volumes by 55% (DI) over CI increased leaf water deficit by 27% and reduced 'Valencia' fruit growth by 15% but not shoot or trunk growth. Similar water savings by PRD did not induce significant growth reductions. Differences in fruit growth rates determined 17% yield reduction in DI but not PRD trees. If we consider integrals of data across each season, PRD induced milder soil and leaf water deficit than DI but similar stomatal conductance. Tree daily water consumption (Etree) estimated from daily leaf transpiration was significantly lower in PRD and DI than in CI. Fruit growth efficiency (growth rate per unit Etree) was similar in all irrigation treatments, while shoot growth efficiency was higher in PRD than in CI. In PRD, an increased shoot growth efficiency rather than fruit growth efficiency is most likely due to water and assimilates being diverted from fruit to shoot growth under high VPD conditions. Although these results show good evidence of an irrigation placement effect inducing an advantage of the PRD strategy in 'Valencia' orange in terms of milder soil and leaf water deficit and more sustainable fruit growth compared to DI, PRD did not induce any significant advantage in terms of final yield over a simple reduction of irrigation volumes

Anti-CA15.3 and anti-CA125 antibodies and ovarian cancer risk: Results from the EPIC cohort

BACKGROUND: Neoplastic and non-neoplastic events may raise levels of mucins, CA15.3 and CA125, and generate antibodies against them; but their impact on epithelial ovarian cancer (EOC) risk has not been fully defined. METHODS: CA15.3, CA125, and IgG1 antibodies against them were measured in 806 women who developed EOC and 1,927 matched controls from the European Prospective Investigation of Nutrition and Cancer. Associations between epidemiologic factors and anti-mucin antibodies were evaluated using generalized linear models; EOC risks associated with anti-mucin antibodies, by themselves or in combination with respective antigens, were evaluated using conditional logistic regression. RESULTS: In controls, lower antibodies against both mucins were associated with current smoking; and, in postmenopausal women, higher levels with longer oral contraceptive use and later-age-at and shorter-interval-since last birth. Lower anti-CA15.3 antibodies were associated with higher body mass and, in premenopausal women, more ovulatory cycles. Higher anti-CA15.3 and anti-CA125 antibodies were associated with higher risk for mucinous EOC occurring ≥ 3 years from enrollment. Long-term risk for serous EOC was reduced in women with low CA125 and high anti-CA125 antibodies relative to women with low concentrations of both. CONCLUSIONS: We found general support for the hypothesis that anti-mucin antibody levels correlate with risk factors for EOC. Antibodies alone or in combinations with their antigen may predict longer term risk of specific EOC types. IMPACT: Anti-CA125 and anti- CA15.3 antibodies alone or in perspective of antigens may be informative in the pathogenesis of EOC subtypes, but less useful for informing risk for all EOC

Guia de pràctica clínica sobre el maneig i tractament d’úlceres d’extremitats inferiors

Úlceres; Extremitats inferiors; Cures; EpidemiologiaÚlceras; Extremidades inferiores; Curas; EpidemiologíaUlcers; Lower extremities; Cures; EpidemiologyLes úlceres cròniques en les extremitats inferiors són un problema de salut amb importants repercussions socioeconòmiques a causa de la seva llarga evolució. Pot minvar la qualitat de vida del pacient i propiciar l’absentisme laboral, i constitueix un gran repte per als professionals sanitaris. L'objectiu d'aquest document és oferir al professional un coneixement actualitzat sobre les millors actuacions preventives i curatives en el maneig i tractament de les úlceres d’extremitat inferior. També facilitar informació sobre mesures diagnòstiques i terapèutiques per a cada situació clínica, per poder millorar la qualitat i eficiència de les cures proporcionades des d'una perspectiva holística i individualitzada

Anti-CA15.3 and anti-CA125 antibodies and ovarian cancer risk : Results from the EPIC cohort

BACKGROUND: Neoplastic and non-neoplastic events may raise levels of mucins, CA15.3 and CA125, and generate antibodies against them; but their impact on epithelial ovarian cancer (EOC) risk has not been fully defined. METHODS: CA15.3, CA125, and IgG1 antibodies against them were measured in 806 women who developed EOC and 1,927 matched controls from the European Prospective Investigation of Nutrition and Cancer. Associations between epidemiologic factors and anti-mucin antibodies were evaluated using generalized linear models; EOC risks associated with anti-mucin antibodies, by themselves or in combination with respective antigens, were evaluated using conditional logistic regression. RESULTS: In controls, lower antibodies against both mucins were associated with current smoking; and, in postmenopausal women, higher levels with longer oral contraceptive use and later-age-at and shorter-interval-since last birth. Lower anti-CA15.3 antibodies were associated with higher body mass and, in premenopausal women, more ovulatory cycles. Higher anti-CA15.3 and anti-CA125 antibodies were associated with higher risk for mucinous EOC occurring ≥ 3 years from enrollment. Long-term risk for serous EOC was reduced in women with low CA125 and high anti-CA125 antibodies relative to women with low concentrations of both. CONCLUSIONS: We found general support for the hypothesis that anti-mucin antibody levels correlate with risk factors for EOC. Antibodies alone or in combinations with their antigen may predict longer term risk of specific EOC types. IMPACT: Anti-CA125 and anti- CA15.3 antibodies alone or in perspective of antigens may be informative in the pathogenesis of EOC subtypes, but less useful for informing risk for all EOC

Guia de pràctica clínica sobre el maneig i tractament d’úlceres d’extremitats inferiors

Úlceres; Extremitats inferiors; Cures; EpidemiologiaÚlceras; Extremidades inferiores; Curas; EpidemiologíaUlcers; Lower extremities; Cures; EpidemiologyLes úlceres cròniques en les extremitats inferiors són un problema de salut amb importants repercussions socioeconòmiques a causa de la seva llarga evolució. Pot minvar la qualitat de vida del pacient i propiciar l’absentisme laboral, i constitueix un gran repte per als professionals sanitaris. L'objectiu d'aquest document és oferir al professional un coneixement actualitzat sobre les millors actuacions preventives i curatives en el maneig i tractament de les úlceres d’extremitat inferior. També facilitar informació sobre mesures diagnòstiques i terapèutiques per a cada situació clínica, per poder millorar la qualitat i eficiència de les cures proporcionades des d'una perspectiva holística i individualitzada