Simulation of many-qubit quantum computation with matrix product states

Matrix product states provide a natural entanglement basis to represent a quantum register and operate quantum gates on it. This scheme can be materialized to simulate a quantum adiabatic algorithm solving hard instances of a NP-Complete problem. Errors inherent to truncations of the exact action of interacting gates are controlled by the size of the matrices in the representation. The property of finding the right solution for an instance and the expected value of the energy are found to be remarkably robust against these errors. As a symbolic example, we simulate the algorithm solving a 100-qubit hard instance, that is, finding the correct product state out of ~ 10^30 possibilities. Accumulated statistics for up to 60 qubits point at a slow growth of the average minimum time to solve hard instances with highly-truncated simulations of adiabatic quantum evolution.Comment: 5 pages, 4 figures, final versio

Anti-Angiogenic Treatment (Sunitinib) for Disseminated Malignant Haemangiopericytoma: A Case Study and Review of the Literature

Introduction: A meningeal haemangiopericytoma (HP) is a mesenchymal tumour that makes up less than 1% of all CNS tumours. HPs arise from pericytes and present high rates of recurrence and distant metastasis. The primary treatment option is surgery. When the disease is disseminated, chemotherapy produces a weak and short-lived response; therefore, new drugs are needed. Case Presentation: We describe the case of a 65-year-old woman with a 13-year history of recurrent HP. After local treatment with radiotherapy, she developed metastases that required systemic treatment, and treatment with sunitinib, an oral inhibitor of the vascular endothelial growth factor receptor and the platelet-derived growth factor receptor, was initiated. As a result, radiological stabilisation of the systemic disease was maintained for over 12 months. Conclusions: Anti-angiogenic agents can be useful for treating disseminated HP, but further studies are needed to confirm their possible role in controlling metastatic disease

Infecciones orofaciales de origen odontogénico

La naturaleza polimicrobiana de las infecciones odontógenas así como la heterogeneidad de los cuadros clínicos asociados son consecuencia de la diversidad de la microbiota bucal y de la complejidad anatómica y funcional de la cavidad oral. Así mismo, estos procesos pueden dar lugar a múltiples complicaciones que pueden limitarse a afecciones locales o derivar hasta compromisos sistémicos. En el tratamiento farmacológico de estas infecciones es crucial la elección del antibiótico y la pauta posológica más eficaces. La farmacodinamia proporciona los parámetros que hacen posible valorar como varía la actividad de los antibióticos en función del tiempo. Como norma general, en el manejo inicial de las infecciones orofaciales en el adulto, incluidas las infecciones odontógenas, se utilizará amoxicilina/ac. Clavulánico en dosis de 875 mg de amoxicilina y 125 mg de ac. clavulánico pautado cada 8 horas. El cumplimiento terapéutico es clave para evitar la aparición de resistencias, por lo que se ha de maximizar la aceptación por parte de los pacientes. En este sentido se ha demostrado que la nueva presentación de 2000/125 mg de Augmentine Plus pautado cada 12 horas tanto en profilaxis como tratamiento disminuye significativamente la tasa de complicaciones infecciosas derivada de la extracción del tercer molar.The polymicrobial nature of the odontogenic infections as well as the variety of associated conditions are a consequence of the diversity of the buccal microbiota and the anatomical and functional complexity of the oral cavity. In addition to this, all these processes can give way to multiple complications which range from the local to the systemic level. The appropriate choice of antibiotic and posology is crucial in the successful management of these infections. Pharmacodynamics provides those parameters that make it possible to assess how antibiotics activity varies in time. As a general rule, the first step in the initial management of orofacial infections in adults, included odontogenic infections, will be the administration of 875 mg of amoxicillin and 125 mg of clavulanic every 8 hours. Therapeutic compliance is paramount to avoid resistance, therefore patient's acceptance must be sought. In this sense, it has been proved that Augmentine Plus (2000/125) every twelve hours both as profylaxis and as treatment significantly decreases the rate of infective complications associated to extraction of the third molar

Study of the phase transition in the 3d Ising spin glass from out of equilibrium numerical simulations

Using the decay of the out equilibrium spin-spin correlation function we compute the equilibrium Edward-Anderson order parameter in the three dimensional binary Ising spin glass in the spin glass phase. We have checked that the Edward-Anderson order parameter computed from out of equilibrium numerical simulations follows with good precision the critical law as determined in experiments and in numerical studies at equilibrium. We have also studied the dependence of the order parameter with the lattice size. Finally we present a large time study of the scaling of the off-equilibrium fluctuation-dissipation relations.Comment: 14 pages, 7 Postscript figure

Ac magnetic susceptibility of a molecular magnet submonolayer directly patterned onto a microSQUID sensor

We report the controlled integration, via Dip Pen Nanolithography, of monolayer dots of ferritin-based CoO nanoparticles (12 Bohr magnetons) into the most sensitive areas of a microSQUID sensor. The nearly optimum flux coupling between these nanomagnets and the microSQUID improves the achievable sensitivity by a factor 100, enabling us to measure the linear susceptibility of the molecular array down to very low temperatures (13 mK). This method opens the possibility of applying ac susceptibility experiments to characterize two-dimensional arrays of single molecule magnets within a wide range of temperatures and frequencies.Comment: 4 pages 3 figure

Use of a new ocular insert versus conventional mydriasis in cataract surgery

Background. To compare the efficacy and safety of a new ocular insert versus conventional mydriasis in cataract surgery. Methods. We selected 70 patients undergoing cataract surgery. Thirty five patients (Group 1) received instillation of mydriatic drops (tropicamide 1%, phenylephrine 10%, and cyclopentolate 1%) prior to surgery, and 35 patients (Group 2) had a Mydriasert insert (Théa Pharma) (0.28¿mg of tropicamide and 5.4¿mg of phenylephrine hydrochloride) placed in the inferior fornix. Pupil size before and after surgery, blood pressure, and heart rate were measured. Results. Before surgery, pupil diameter was ¿mm in Group 1 and in Group 2 ( ). Twenty four hours after surgery, pupil diameter was ¿mm in Group 1 and in Group 2 ( ). There were no statistically significant differences in blood pressure or heart rate between groups. Conclusions. The effect of the Mydriasert insert was similar to conventional mydriatic agents. Pupil size was restored to normal faster when using the Mydriasert insert compared with conventional mydriatic agents for pupil dilation

Granada é uma cidade onde a actividade física é incentivada no ensino primário?

Resumen: Introducción: Tras la diferenciación entre actividad física y ejercicio físico. Contenido: Veremos todos los beneficios que aporta la primera. Resaltaremos la importancia que tiene la actividad física dentro del horario escolar y si el tiempo dedicada a la misma es suficiente para el correcto desarrollo del alumno o alumna. Proseguiremos con las opciones que pueden ofre-cerse en cuanto a actividad física en el centro y fuera del mismo, y nos centraremos en la oferta que da la provincia de Gra-nada en actividades físico-deportivas en el medio natural; tanto agua, como nieve y montaña. Hablaremos de los factores que influyen en la participación o abandono de las actividades físicas; como el sexo, la edad o las características familiares. Conclusión: Para terminar, hemos concluido que Granada es una provincia rica en actividades físico deportivas.Abstract: Introduction: After differentiating between physical activity and physical exercise. Contens: We will see all the benefits of the first. We will emphasize the importance of physical activity within the school schedule and if the time dedicated to it is suffi-cient for the correct development of the student. We will continue with the options that can be offered in terms of physical activity in the school and outside it, and we will focus on the offer of the province of Granada in physical-sports activities in the natural environment; both water, snow and mountain. Finally, we will talk about the factors that influence in the partici-pation or abandonment of physical activities; such as sex, age or family characteristics. Conclusion: To conclude, we have concluded that Granada is a province rich in physical sports activities.Resumo: Introdução: Após a diferenciação entre a actividade física e o exercício físico. Conteúdo: Veremos todos benefícios do primeiro. Destacaremos a importância da actividade e se o tempo que lhe for dedicado for suficiente para que o aluno seja capaz de desenvolvimento correcto do aluno. Vamos continuar com as opções que podem oferta em termos de actividade física no centro e no exterior, e vamos concentrar na oferta apresentada pela província de Granada em actividades físico-desportivas na zona água, neve e montanhas. Para concluir, vamos falar sobre os factores que influenciam a participação em actividades físicas ou o abandono das mesmas, tais como sexo, género, etc. idade ou características familia-res.Conclusão: Para concluir, concluímos que Granada é uma província rica em actividades físicas desportivas

Epidemiology of injuries in professional and amateur spanish paddle players

Se realizó un estudio epidemiológico descriptivo, observacional y retrospectivo, analizando la incidencia y las características de las lesiones sufridas por jugadores de pádel españoles profesionales y no profesionales. Se registraron las lesiones sufridas por 478 jugadores entre el 1 de enero y el 31 de diciembre de 2016. Se registraron datos sobre el número de lesiones, lesiones más frecuentes, distribución, tipo, ubicación, el momento en que ocurrieron y la causa de las lesiones que afectan el sistema locomotor. La tasa de lesiones en esta población fue de 2,75 lesiones por 1000 horas de exposición al riesgo. Las lesiones leves y aquellas con mecanismos de lesión intrínseca fueron las más frecuentes, y tuvieron lugar el final de la práctica deportiva. La extremidad inferior fue el área corporal más lesionada, y el tejido más lesionado fue el sistema musculo-tendinoso. A su vez, la epicondilitis fue la patología más comúnAn epidemiological study was conducted using retrospective, observational and descriptive methodologies. We sought to analyse the incidence and features of injuries sustained by professional and non-professional Spanish Padel players. In total, 478 injuries were registered in 2016 from January 1st to December 31st. We collected data on the number of injuries, the most frequent injuries, their distribution, type, location, the moment at which these occurred and the cause of the injuries affecting the locomotor system. We found that the injury rate in this population was 2.75 injuries per 1000 hours of risk exposure. The most frequent injuries were those which were mild or with mechanisms of intrinsic injury, and most occurred towards the end any given game or practice. The lower limb was the most frequently injured body area, and the most injured tissue was the muscle-tendinous system. In turn, epicondylitis was the most common patholog

Development of a Telemetry and Yield-Mapping System of Olive Harvester

Sensors, communication systems and geo-reference units are required to achieve an optimized management of agricultural inputs with respect to the economic and environmental aspects of olive groves. In this study, three commercial olive harvesters were tracked during two harvesting seasons in Spain and Chile using remote and autonomous equipment that was developed to determine their time efficiency and effective based on canopy shaking for fruit detachment. These harvesters work in intensive/high-density (HD) and super-high-density (SHD) olive orchards. A GNSS (Global Navigation Satellite System) and GSM (Global System for Mobile Communications) device was installed to track these harvesters. The GNSS receiver did not affect the driver’s work schedule. Time elements methodology was adapted to the remote data acquisition system. The effective field capacity and field efficiency were investigated. In addition, the field shape, row length, angle between headland alley and row, and row alley width were measured to determinate the optimum orchard design parameters value. The SHD olive harvester showed significant lower effective field capacity values when alley width was less than 4 m. In addition, a yield monitor was developed and installed on a traditional olive harvester to obtain a yield map from the harvested area. The hedge straddle harvester stood out for its highly effective field capacity; nevertheless, a higher field efficiency was provided by a non-integral lateral canopy shaker. All of the measured orchard parameters have influenced machinery yields, whether effective field capacity or field efficiency. A saving of 40% in effective field capacity was achieved with a reduction from 4 m or higher to 3.5 m in alley width for SHD olive harvester. A yield map was plotted using data that were acquired by a yield monitor, reflecting the yield gradient in spite of the larger differences between tree yield

Tratamiento de las fracturas de tobillo con polaina funcional conformada

Se realiza un estudio retrospectivo sobre 35 fracturas de tobillo tratadas con yeso funcional conformado en período de seguimiento de 1 año, algunas no desplazadas y otras desplazadas, pero en las que fue posible conseguir ortopédicamente o con osteosíntesis «a mínima» una correcta reducción. Para la confección del enyesado funcional conformado (YFC), se siguió el método preconizado por F. Esteve valorando clínicamente movilidad, dolor, marcha y estabilidad y radiográficamente reducción, articulación en carga y consolidación. La edad media fue de 53 años, predominando etiología casual (86% de los casos) y el tipo de fractura las de supinación. La duración del período agudo fue de 3,5 a 4 semanas, la del período funcional de 4 semanas y la del período de readaptación de 2 a 3 semanas. Los resultados, en base a los criterios clínicos y radiológicos, fueron excelentes en el 21 % de los casos, buenos en el 62%, regulares en el 10% y malos en el 7%.A total of 35 ankle fractures treated with a functional below-the-knee brace were retrospectively studied. The follow-up period was one year. There were displaced and non displaced fractures, but in all of them was possible to achieved a satisfactory reduction either orthopaedically or with a minimal osteosynthesis. Functional bellow-the-knee bracings was performed according to Esteve. Different parameters such as motion, pain, walking ability and fracture stability were clinically assesed. Fracture reduction and joint consolidation were radiographically evaluated with weight-bearig in the affected leg. The age average was 53 years. Among fractures predominated casual fall etiology (86%) and supination type. The duration of the no loading immovilization period way 3-4 weeks. The functional casting period was 4 weeks and the readaptative period was 2-3 weeks. Based on the clinical and radiological assessments, the results were excellent in a 2 1 % of cases, good in 67%, fair in 10% and poor in 7%